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Quick Search     Adv Search 2018 Vol. 35, No. 7 Published: 2018-07-31 Orignal Article          Orignal Article 1249 Effect of Different Cardiac Rehabilitation Modes on Quality of Life and Mental State after Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction and Diabetes Mellitus WANG Jun-ling, ZHANG Jian-xiu DOI: 10.3969/j.issn.1671-7171.2018.07.001 【Objective】To compare and analyze the effects of different cardiac rehabilitation models on the quality of life and psychological status of patients with acute myocardial infarction and diabetes after interventional therapy.【Methods】A total of 98 patients with acute myocardial infarction combined with diabetes from January 2016 to September 2017 were selected and divided into 49 cases in the observation group and 49 cases in the control group according to the random table method. The two groups were treated by percutaneous coronary intervention (PCI). The control group received traditional rehabilitation, and the observation group adopted the new mode of cardiac rehabilitation. The changes of heart function, survival treatment, mental state and cardiopulmonary function in two groups before and after rehabilitation were compared.【Results】After rehabilitation, LVEF increased and LVSD and LVDD decreased (the observation group: t=15.042, 19.935, 13.303, t=12.540, 8.895, 7.051, P < 0.05), and the LVEF in the observation group was higher than that of the control group, while LVSD and LVDD were lower than the control group ( t=4.526, 10.862, 6.573, P < 0.05). The two groups increased the environmental, social, psychological, physiological, and total sensory scores after the two groups (observation group: t=31.272, 28.836, 25.815, 25.390, 23.325, t=14.162, 12.223, 19.745, 19.395, 17.399, P < 0.05), and the field of environmental, social relations, and psychology of the observation group after rehabilitation. The scores in the field, physiology and general feeling were higher than those in the control group ( t=13.247, 10.018, 9.657, 7.648, 8.102, P < 0.05). The scores of SAS and SDS in the two groups were reduced (the observation group: t=18.873, 22.187, the control group: t=14.350, 10.897, P < 0.05), and the SAS and SDS scores in the observation group were lower than those of the control group ( t=6.845, 14.759, P < 0.05). The increase of VO2max/HR and METmax after rehabilitation in the two groups (observation group: t =16.743, 12.688, control group: t=7.231, 7.889,P < 0.05), VO2max/HR and METS in the observation group were higher than those of the control group ( t=9.674, 6.651,P < 0.05).【Conclusion】The new model of cardiac rehabilitation can obviously improve the survival quality of patients with acute myocardial infarction combined with diabetes interventional therapy, and it can improve the mental state of the patients, which is worthy of clinical study. 2018 Vol. 35 (7): 1249-1251 [Abstract] ( 37 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1252 Treatment of Myasthenia Gravis with Small Thymoma by Thoracoscopic Extended Thymectomy ZHANG Xiao-he, QI Guo-yan, ZHANG Tai-ming, et al DOI: 10.3969/j.issn.1671-7171.2018.07.002 【Objective】To investigate the operation, prognosis and curative effect of thoracoscopic thymic enlargement in the treatment of patients with myasthenia gravis (MG) complicated with microthymoma and thymic hyperplasia.【Methods】 A total of 84 patients with MG who were admitted to our hospital from July 2012 to July 2016 were enrolled. The patients were divided into the small thymoma group ( n =46) and the thymic hyperplasia group( n =38)according to the combination of microthymoma or thymic hyperplasia. All patients underwent thoracoscopic thymectomy, and the surgical results of the two groups were observed and the prognosis was followed up for 6 months. Univariate analysis was performed on the relationship between patients' general data, thymic pathology type and curative effect, and logistic regression model was used to analyze the influencing factors.【Results】For the general data, the effect of age less than 40 years was significantly better than that of those older than 40 years old. The operation time, intraoperative blood loss, total length of incision, drainage tube retention time, hospitalization time and other basic conditions were compared between the two groups. The difference was not statistically significant ( P > 0.05). There was no significant difference in postoperative complications between the two groups ( P > 0.05). After follow-up for 6 months, the postoperative pathological thymic hyperplasia group was better than the small thymoma group. In the logistic regression model, age was still the most important factor in comparison with postoperative pathology.【Conclusion】By logistic regression analysis, the patients with MG complicated with small thymoma had severe symptoms before operation. The effect of thoracoscopic extended resection on MG with microthymoma was positive, but the effect of operation was a little worse than that of patients with thymus hyperplasia, and there was no difference in postoperative complications. It is worth popularizing and applying in clinic because of the quick recovery after operation. 2018 Vol. 35 (7): 1252-1255 [Abstract] ( 50 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1256 Iron Overload in Children with Thalassemia and its Relationship with Thyroid Function ZHANG Yang, FANG Min-chao, LIAO Ying-jin, et al DOI: 10.3969/j.issn.1671-7171.2018.07.003 【Objective】 To explore the relationship between iron overload and thyroid function in children with thalassemia . 【Methods】 From June 2014 to June 2017, 118 children with thalassemia were selected to detect serum ferritin (SF), free triiodothyronine (FT3) and serum free thyroid hormone (FT4). The level of thyroid stimulating hormone (TSH) was observed and the relationship between iron overload and hypothyroidism was analyzed.【Results】 Among the 118 children with thalassemia who received regular blood transfusion and iron removal, 53 had no iron overload (44.92%), 65 had iron overload (55.08%), and the serum FT3 ,FT4 of iron overload children was significantly lower than that of non-iron overload children. The prevalence of hypothyroidism was significantly higher than that of children without iron overload ( P < 0.05).【Conclusion】 Children with thalassemia may be accompanied by iron overload after transfusion, and iron overload may increase the incidence of complications of hypothyroidism to a certain extent. 2018 Vol. 35 (7): 1256-1257 [Abstract] ( 29 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1258 Application of Orem Self-care Model in Nursing Care of Patients with Advanced Lung Cancer Wu Li-na, YAO Hai-rong, WANG Ying, et al DOI: 10.3969/j.issn.1671-7171.2018.07.004 【Objective】To explore the effect of nursing measures based on Orem self-care mode in the nursing of patients with advanced lung cancer.【Methods】One hundred and twenty-eight patients with advanced lung cancer admitted in our hospital from April 2016 to November 2017 were randomly divided into two groups: the observation group and the control group. The control group was given routine nursing care. The observation group was given Orem nursing care model on the basis of the control group and both groups intervened for 1 month. The scores of hospital anxiety and depression scale (Hospital Anxiety and Depression Scale), Pittsburgh sleep quality index and lung cancer core quality of life (Quality of life group of cancer patients QLQ-C43) before and after nursing were compared between the two groups.【Results】There was no significant difference between the two groups at admission ( P > 0.05). After one month of nursing care, the scores of HADS+ PSQI in both groups were significantly lower than those in the control group, and the scores of the functional area and the general health state in the QLQ-C43 score of the two groups were all increased, and the scores of the symptom areas were lower in the observation group than in the control group. The range of changes in the observation group was better than that in the control group, and the difference was statistically significant ( P < 0.05).【Conclusion】The nursing intervention of Orem self-care model can effectively relieve the psychological burden of patients with advanced lung cancer and improve their sleep quality and quality of life. It is worthy of clinical application. 2018 Vol. 35 (7): 1258-1261 [Abstract] ( 30 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1262 Effect of Compound Kushen Injection Combined with Radiotherapy and Chemotherapy on Cervical Cancer CAI Tao, SUN Lan-Zheng, WANG Ting, et al DOI: 10.3969/j.issn.1671-7171.2018.07.005 【Objective】To evaluate the effect of compound Kushen injection combined with radiotherapy and chemotherapy on cervical cancer. 【Methods】The clinical data of 105 patients with cervical cancer who were treated in our hospital from June 2015 to January 2017 were collected. According to different treatment regimens, patients were divided into the single-use group and the combined group. The single-use group consisted of 52 cases who were given concurrent radiotherapy and chemotherapy, while the combined group of 53 cases received the compound Kushen injection plus chemoradiotherapy. T lymphocyte subsets, natural killer cells (NK) and serum tumor antigens [insulin-like growth factor-2 (IGF-2), squamous cell carcinoma-associated antigens were observed before and after treatment for 3 courses. SCC and cytokeratin 19 fragment antigen (CYFRA21-1)] were measured before treatment and after 3 courses of treatment. The therapeutic efficacy and safety between the two groups were evaluated and compared. 【Results】The total effective rate of the combined group was 52.83% (28/53), which was significantly higher than that of the single-use group, which was 32.69% (17/52). The incidence of adverse reactions was 47.17% (25/53) in the combined group, which was lower than in the single-use group, which was 75.00% (39/52). The difference was statistically significant ( P < 0.05). The levels of CD3+, CD4+, CD4+/CD8+ and NK in the combined group were higher than those in the single-use group, and the differences were statistically significant ( P < 0.05). The CD8+ level in the combined group was lower than that in the single-use group ( P < 0.05). After treatment, the levels of IGF-2, SCC and CYFRA21-1 in the combined group were lower than those in the single-use group ( P < 0.05). 【Conclusion】The application of Kushen injection combined with radiotherapy and chemotherapy in patients with cervical cancer is effective in promoting the enhancement of cellular immune function, reducing the level of tumor antigen and reducing the occurrence of adverse reaction. 2018 Vol. 35 (7): 1262-1264 [Abstract] ( 26 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1265 Effect of Adjuvant Therapy with Compound Hongdoushan Capsules on Peripheral Blood T Lymphocyte Subsets and Vascular Endothelial Growth Factors in Patients with Ovarian Cancer Treated with Chemotherapy YU Jing, YE Lin-yan DOI: 10.3969/j.issn.1671-7171.2018.07.006 【Objective】To investigate the effect of adjuvant therapy with Compound Hongdoushan Capsules on peripheral blood T lymphocyte subsets and vascular endothelial growth factors (VEGF) in patients with ovarian cancer treated by chemotherapy after operation. 【Methods】 A total of 88 cases of patients with ovarian cancer treated in our hospital during March 2012 to April 2016 were selected and randomly divided into the control group and the observation group by the random number table method, with 44 cases in each group. Both groups were treated with radical resection of ovarian cancer combined with postoperative chemotherapy, and patients in the observation group were additionally treated with Compound Hongdoushan Capsules. The therapeutic effects were compared between the two groups, and changes of levels of T lymphocyte subsets such as CD3+, CD4+, CD8+, and CD4+/CD8+ in peripheral blood were detected before and after treatment. The changes of VEGF, interleukin -6 (IL-6), interleukin -8 (IL-8), and tumor necrosis factor α (TNF-α) levels were determined before and after treatment, and the incidence of side effects in the two groups was statistically analyzed. 【Results】 The total remission rate of the observation group was higher than that of the control group ( P < 0.05). Before treatment, there was no significant difference in the levels of CD3+, CD4+, CD8+, CD4+/CD8+, IL-6, IL-8, TNF-α, and VEGF between the two groups ( P > 0.05). After treatment, the levels of CD3+, CD4+, and CD4+/CD8+ in the observation group were higher than those in the control group, and the levels of IL-6, IL-8, TNF-α and VEGF in the observation group were lower than those in the control group ( P < 0.05). The incidence rates of grade Ⅰ~Ⅱ gastrointestinal reactions, hematuria, and WBC count decline in the observation group were lower than those in the control group ( P < 0.05). 【Conclusion】The adjuvant therapy with Compound Hongdoushan Capsules has synergistic effects in the chemotherapy of ovarian cancer. It can optimize the effects of chemotherapy, improve the immune function and reduce the side effects. 2018 Vol. 35 (7): 1265-1267 [Abstract] ( 46 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1268 Effects of Different Anesthetic Depths on Stress Injury, Circulatory System and Postoperative Cognitive Function in Children under General Anesthesia OU Ming-ling DOI: 10.3969/j.issn.1671-7171.2018.07.007 【Objective】 To investigate the effect of different depths of anesthesia under bispectral index (BIS) monitoring on stress response, circulatory system and postoperative cognitive function in children receiving general anesthesia. 【Method】 One hundred and fifty cases of children undergoing elective operation under total intravenous anesthesia were divided into group A and group B. The BIS value in the group A was maintained at 40~50 while that in the group B was maintained at < 50~60. The hemodynamic indexes, stress reaction indexes ,MMSE and anaenf esthesia effect at different time points were compared between the two groups. 【Results】At time of completing operation(T3) and 1 day after operation(T5), there was no significant difference in heart rate (HR) and mean arterial pressure (MAP) between the two groups ( P > 0.05). The levels of plasma endothelin-1 (ET-1) and adrenocorticotropic hormone (ACTH), C-reactive protein (CRP) in the group A were significantly lower than those in the group B ( P < 0.05). The scores of MMSE at 24 hours after operation in both groups were significantly lower than those at 1 hour before operation ( P < 0.05), but there was no significant difference in MMSE scores between the two groups at different time points ( P > 0.05), and no significant adverse reactions occurred in both groups.【Conclusion】The hemodynamic stability of children with general intravenous anesthesia is effectively maintained under different anesthetic depths monitored by BIS. The effects of different anesthetic depths on cognitive function of children are similar, but the effect of BIS 40~50 on stress response is less than that of < 50~60. 2018 Vol. 35 (7): 1268-1270 [Abstract] ( 33 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1271 Effects of Different Positions under General Anesthesia on Hemodynamics and Respiratory Dynamics in Patients Undergoing Laryngeal Mask Airway Assisted Ventilation YONG Ji-zhi DOI: 10.3969/j.issn.1671-7171.2018.07.008 【Objective】To investigate the effect of lithotomy position and horizontal position on hemodynamics, respiratory mechanics and incidence of adverse reactions in patients with laryngeal mask airway(LMA) assisted ventilation under general anesthesia. 【Methods】Eighty-eight cases of patients were divided into lithotomy position group(group A) and horizontal position group(group B). Changes of hemodynamic parameters before induction of anesthesia (T0), 1min (T1), 30min (T2) and 60min (T3) after LMA mask insertion and at extubation (T4) were recorded. Changes of respiratory mechanics at T1, T2 and T3 were recorded. 【Results】The heart rate (HR) and mean arterial pressure (MAP) at T2 in the two groups were significantly lower than those of T0 ( P < 0.05),there was no significant difference of HR and MAP between the two groups at the same time point ( P > 0.05). The peak inspiratory pressure, plateau pressure, peak expiratory flow, inspiratory resistance, expiratory resistance and work of breathing in the two groups increased gradually over time while peak inspiratory flow, expiratory end partial pressure of carbon dioxide (PETCO2), dynamic compliance and static compliance decreased gradually. At T2 and T3, the peak inspiratory pressure, plateau pressure, inspiratory resistance, expiratory resistance and work of breathing of the group A were significantly lower than those of the group B ( P < 0.05). At T1, T2 and T3, the peak inspiratory flow, peak expiratory flow, dynamic compliance and static compliance of the group A were significantly higher than those of the group B ( P < 0.05). There was no significant difference in PETCO2 between the two groups ( P > 0.05), and there was no significant difference in the incidence of adverse reactions between the two groups ( P > 0.05). 【Conclusion】Under general anesthesia, both of lithotomy position and horizontal position of LMA ventilation on hemodynamics shows no significant difference between the two positions ,but the effect of horizontal position on respiratory dynamics is significantly less, and there were no serious adverse reactions under the two kinds of positions. 2018 Vol. 35 (7): 1271-1273 [Abstract] ( 40 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1274 Effect of Psychological Intervention in Combination with Herbal Fumigation on Stress Reaction and Sensory Disturbance of Patients Undergoing Procedures for Prolapsed Hemorrhoids (PPH) LI Juan DOI: 10.3969/j.issn.1671-7171.2018.07.009 【Objective】To investigate the effect of psychological intervention in combination with herbal fumigation on stress reaction and sensory disturbance of patients undergoing procedures for prolapsed hemorrhoids (PPH).【Methods】A total of 124 cases of patients with sensory disturbance after PPH who were admitted to our hospital from January 2015 to June 2016 were selected as the research subjects and divided into the observation group and the control group using the random number table method, with 62 cases in each group. All the patients received conventional antibiotics for infection prevention and pain-killing treatment. Patients in the control group were also given traditional Chinese herbal fumigation, while patients in the observation group received psychological intervention on the basis of the control group. The scores of physiological stress reaction and sensory disturbance, clinical efficacy and other indicators between the two groups were compared.【Results】The effective rate in the observation group was 91.94%, which was significantly higher than that of 75.81% in the control group ( P < 0.05). The levels of serum 5-hydroxytryptamine (5-HT), prostaglandin E2 (PGE2) and histamine (HA) were significantly lower than those in control group ( P < 0.05). The scores of pain, fall-swell and urination disorder were significantly lower than those in control group as well ( P < 0.01).【Conclusion】Psychological intervention in combination with herbal fumigation can help to relieve the physiological stress reaction of patients undergone PPH, improve the postoperative sensory disturbance, and enhance the clinical efficacy. 2018 Vol. 35 (7): 1274-1276 [Abstract] ( 26 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1277 Effect of Paclitaxel Cisplatin Chemotherapy Combined with Three-dimensional Conformal Radiotherapy on Postoperative Recurrence and Metastasis in Patients with Cervical Cancer undergoing Radical Resection FANG Lin, LI Rong, LUO Juan DOI: 10.3969/j.issn.1671-7171.2018.07.010 【Objective】To investigate the effect of paclitaxel (PTX) and cisplatin (DDP) (TP) combined with concurrent three dimensional conformal radiation therapy(3D-CRT) on recurrence and metastasis in patients with cervical cancer after radical hysterectomy. 【Methods】Eighty-four cases of patients with cervical cancer were retrospectively analyzed. Both groups were treated by radical hysterectomy for cervical cancer. After operation, 40 cases undergoing concurrent radiochemotherapy were included into group A, while 44 cases undergoing radiotherapy alone were divided into group B. The A group was treated with TP chemotherapy and 3D-CRT , while the group B was treated with 3D-CRT . The curative effect and incidence of side effects were compared between the two groups. And the recurrence rate, metastasis rate and survival rate were statistically analyzed. 【Results】The complete remission rate and the objective effective rate in the group A (30% and 82.50%) were significantly higher than those in the group B (11.36% and 61.36%) (P< 0.05). the incidence rates of different grades of gastrointestinal reactions, bone marrow suppression, radiation cystitis and grade Ⅰ~Ⅱ platelet count decline in the group A were slightly higher than those in the group B ( P > 0.05). The recurrence rates and metastasis rates in the group A were slightly lower than those in the group B 2 years and 3 years after operation ( P > 0.05). The 3-year survival rate and the total survival time of the group A were higher or longer than those of the group B ( P < 0.05). 【Conclusion】 TP chemotherapy with concurrent 3D-CRT can improve the effect of tumor control and prolong the survival time of patients. 2018 Vol. 35 (7): 1277-1279 [Abstract] ( 27 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1280 Application and Diagnostic Value of MRI and CT in the Diagnosis of Hepatoma Adenoma YU Xiao-ping, HAO Yin-yin, ZHANG Yong DOI: 10.3969/j.issn.1671-7171.2018.07.011 【Objective】To explore the diagnostic value of MRI and CT in hepatoma adenoma(HCA). 【Methods】Fifty-six cases of suspected hepatocellular carcinoma underwent MRI and CT examination. The value of CT, MRI and their combined detection in diagnosis of hepatocellular adenoma was analyzed by receiver operating characteristic curve (ROC). 【Results】(1) The pathological diagnosis of 45 cases of liver cell adenoma in 56 cases, (2) the sensitivity, specificity, and accuracy of CT in the diagnosis of hepatocellular adenoma were 81.82%, 80%, 80.36%; the sensitivity, specificity and accuracy of MRI diagnosis of hepatocellular adenoma were 91.11%, 63.64%, 85.71%; the sensitivity, specificity, accuracy of CT+MRI diagnosis of liver cell adenoma were 97.78%, 72.73%, 93.62%; AUCCT+MRI>AUCCT( Z=2.356,P =0.019), AUCCT+MRI>AUCMRI( Z=1.612,P =0.107), AUCMRI>AUCCT( Z=1.556,P =0.120). 【Conclusion】CT scanning analysis and MRI scan have certain differential diagnostic value for hepatocellular adenoma. The combined detection can improve the accuracy of diagnosis. 2018 Vol. 35 (7): 1280-1282 [Abstract] ( 39 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1283 Clinical Observation of Guanxin Tongluo Decoction in the Treatment of Senile Acute Myocardial Infarction MA Xiao-mei DOI: 10.3969/j.issn.1671-7171.2018.07.012 【Objective】 To investigate the clinical effect of Guanxin Tongluo recipe in the treatment of senile acute myocardial infarction (AMI). 【Methods】The clinical data of 62 elderly patients with AMI were collected from June 2015 to May 2017. According to the random number table method, they were divided into observation group and control group with 31 cases in each group. The control group was treated with clopidogrel orally on the basis of routine treatment, while the observation group was treated with Guanxin Tongluo decoction on the basis of routine treatment. The clinical efficacy and the level of growth differentiation factor-15 (GDF-15) were observed and recorded in both groups. Left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), (SV), effective cardiac output (CO), cardiac index (CI) and left ventricular ejection fraction (LVEF) were measured by color ultrasound. 【Results】 After treatment, the total effective rate in the observation group was 96.77% (30/31), which was significantly higher than that in the control group (61.29%) (19/31), and the difference was statistically significant (χ2=3.757) (P< 0.05). After treatment, the level of LVEDVV/LVESV in the observation group was significantly lower than that in the control group (P< 0.05), SV and LVEF levels were significantly higher than those in the control group, the difference was statistically significant (mean P < 0.05), and there was no significant difference in the levels of CO and CI between the two groups ( P > 0.05). After treatment, the serum GDF-15 level in the observation group was significantly lower than that in the control group [(873.68± 88.62)g/L vs (1037.25± 97.38) g/L]( P < 0.05). 【Conclusion】The application of Guanxin Tongluo recipe in the treatment of elderly patients with AMI can significantly reduce the level of serum GDF-15 and improve the ventricular remodeling and cardiac function of the patients. 2018 Vol. 35 (7): 1283-1285 [Abstract] ( 36 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1286 Effect of Docetaxel Combined with Capecitabine and Oxaliplatin on Serum Levels of Tumor Markers in Patients with Advanced Gastric Cancer ZHANG Nu, WANG Jing, CHEN Zhen-lin, et al DOI: 10.3969/j.issn.1671-7171.2018.07.013 【Objective】To investigate the effect of docetaxel combined with capecitabine and oxaliplatin on serum levels of tumor markers in patients with advanced gastric cancer. 【Methods】Sixty patients with advanced gastric cancer were analyzed retrospectively. According to different chemotherapy regimens, the patients were divided into FOLFOX group (group A ,calcium folinate +5- fluorouracil + oxaliplatin, n=28) and group DOX (group B,docetaxel + capecitabine + oxaliplatin, n =32). The effects of chemotherapy were compared between the two groups, and changes of serum levels of tumor markers carbohydrate CA125, CEA,TPS,CA199, CYFRA21-1 in the two groups before and after treatment were monitored. The changes of serum levels of IL-2, TNF-α, VEGF and NO were compared between the two groups before and after treatment. 【Results】①The total remission rate of the group B was slightly higher than that of the group A ( P > 0.05). ②Before chemotherapy, there were no statistically significant differences between the two groups in levels of CA125, CEA, TPS, CYFRA21-1, CA199, IL-2, TNF-α, VEGF and NO ( P > 0.05), after treatment, the above indexes were decreased in the two groups ( P < 0.05), and the levels of tumor markers in the group B were lower than those in the group A ( P < 0.05). ③The incidence of side effects in the group B was slightly lower than that in the group A ( P > 0.05). 【Conclusion】The total remission rate of patients with advanced gastric cancer treated by DOX chemotherapy is high and the tolerance of patients is good. Meanwhile, the regimen can decrease the levels of serum tumor markers, inflammation and vascular endothelial factors. 2018 Vol. 35 (7): 1286-1288 [Abstract] ( 42 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1289 Clinical Effect and Influence of Lock Plate and Anatomical Plate Fixation on Ankle Function in the Treatment of Pilon Fracture DUAN Xian-bin, LU Xiao-hu, PEI Zhi-jie DOI: 10.3969/j.issn.1671-7171.2018.07.014 【Objective】To compare the clinical effect of lock plate and anatomical plate fixation in the treatment of Pilon fracture, and to analyze its influence on ankle function. 【Methods】A total of 80 patients with Pilon fracture were selected as study subjects. They were divided into the control group and the observation group, with 40 cases in each group. All patients underwent open reduction and internal fixation. The control group was subjected to anatomic plate fixation, while the observation group received lock plate fixation. The surgical indicators, the incidence of complications, clinical curative effect and ankle joint function related index before and after the treatment of two groups were compared. 【Results】The operation time, intraoperative blood loss, healing time and length of hospital stay in the observation group were less than those in the control group; the differences were statistically significant(P< 0.05).The postoperative complication rate of the observation group was obviously less than that of the control group; the difference was statistically significant(P< 0.05). The total effective rate in the observation group was higher than that in the control group with statistical significance (P< 0.05).The different values of ankle height, width and depth of patients in the two groups after treatment were lower than those before treatment. In addition, these ankle joint function indicators in the observation group after treatment were significantly less than those in the control group, and the differences were statistically significant (P< 0.05). 【Conclusion】Compared to anatomic plate fixation, lock plate internal fixation in the treatment of Pilon fracture is less traumatic to the body, causes fewer postoperative complications, has better efficacy, results in better recovery of ankle joint function, and is worthy of clinical application. 2018 Vol. 35 (7): 1289-1291 [Abstract] ( 23 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1292 Effect ticagrelor and clopidogrel on platelet function and platelet inhibition in patients with ACS after PCI ZHENG Yan-e, LUO Hui, YANG Hang, et al DOI: 10.3969/j.issn.1671-7171.2018.07.015 【Objective】To investigate and compare the effect of ticagrelor and clopidogrel on platelet function and platelet inhibition in patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI). 【Methods】A total of 106 cases of ACS patients undergoing elective PCI in the hospital were divided into the ticagrelor group and the clopidogrel group by random number table method, 53 cases in each group. The maximum platelet aggregation rate (MPAR) and plasma P2Y12 response uni (PRU) were compared. The resistance to antiplatelet drugs in 24 hours after PCI was determined with arachidonic acid (AA) and adenosine diphosphate (ADP) as activators. All patients were followed up for 1 year after operation, the incidence of clinical end point events was recorded, and adverse drug reactions were statistically analyzed. 【Results】 24 hours and 7 days after operation, MPAR and PRU were lower in ticagrelor group than clopidogrel group ( P < 0.05). ADP inhibition rate was higher in ticagrelor group than clopidogrel group, and the proportion of ADP inhibitor < 30% was significantly lower in ticagrelor group than clopidogrel group (3.77% vs 32.08%) ( P < 0.05). The incidence of clinical end point events in ticagrelor group in 1 year after operation was lower than that in clopidogrel group (11.32% vs 33.96%) (χ2=7.756, P < 0.05). The incidence of adverse drug reactions showed no significant difference between the two groups (16.98% vs 13.21%) (χ2=0.294, P > 0.05). 【Conclusion】Ticagrelor is superior to clopidogrel in inhibiting platelet aggregation after PCI in patients with ACS, and the incidence of tigrilol resistance is lower, which could reduce the incidence of clinical endpoint events and had high safety. 2018 Vol. 35 (7): 1292-1295 [Abstract] ( 37 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1295 Influence of Empathy Nursing Combined with Relaxation Training on Anxiety, Depression, and Sleep Quality of COPD Patients DAI Jin-lan, HAN Ying, CHEN Qian DOI: 10.3969/j.issn.1671-7171.2018.07.016 【Objective】 To investigate the effect of empathy nursing in combination with relaxation training on anxiety-depression mood and sleep quality of patients with chronic obstructive pulmonary disease (COPD). 【Methods】A total of 114 cases of COPD patients hospitalized from July 2016 to June 2017 were selected as the research subjects, and divided into the observation group and the control group according to the random number table method, with 57 cases in each group. Patients in control group were given routine nursing, while patients in observation group were given empathy nursing in combination with relaxation training in addition to regular nursing. After 8 weeks of follow-up interventions, the anxiety-depression mood and sleep quality of patients in the two groups were evaluated by the self-rating anxiety scale (SAS), self-rating depression scale (SDS) ,and Pittsburgh sleep quality index (PSQI). 【Results】 The scores of SAS and SDS in observation group were significantly lower than those in the control group ( P < 0.05), and the scores of PSQI such as fall-sleep time and sleeping time were significantly lower than those in the control group ( P < 0.05, P < 0.01). 【Conclusion】Empathy nursing in combination with relaxation training can help to improve anxiety-depression mood and sleep quality of COPD patients, and enhance the physical and mental comfort level. 2018 Vol. 35 (7): 1295-1297 [Abstract] ( 40 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1298 Effect of Negative Pressure Drainage Combined with Recombinant Human Growth Hormone on Elderly Diabetic Foot WU Xiao-hua, XU Jin-chuan, LV Jing-mei, et al DOI: 10.3969/j.issn.1671-7171.2018.07.017 【Objective】 To investigate the effect of negative pressure and recombinant human growth hormone on senile diabetic foot. 【Methods】One hundred and two senile diabetic foot patients were randomly divided into observation group and control group with 51 cases in each group. The patients in the control group were treated with negative pressure drainage, and the patients in the observation group were treated with recombinant human growth hormone on the basis of the control group. The curative effect, wound healing, hospital stay, pain improvement and serum levels of insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) were compared between the two groups before and after treatment. 【Results】 The total effective rate of treatment in the observation group was 94.12, which was significantly higher than that in the control group (76.47%), and the difference was statistically significant ( P < 0.05). The granulation tissue thickness and wound healing time in the observation group were better than those in the control group ( P < 0.05). The time of hospitalization in the observation group was shorter than that in the control group ( P < 0.05). The levels of serum IGF-1 and IGFBP-3 in the control group were not significantly changed before and after treatment ( P > 0.05), and the levels of serum IGF-1 and IGFBP-3 in the observation group increased after treatment ( P < 0.05) and were higher than those in the control group ( P < 0.05). 【Conclusion】 Negative pressure of wound combined with recombinant human growth hormone is effective in treating senile diabetic foot patients. It can promote wound healing and increase serum IGF-1 and IGFBP-3 levels, which is worthy of clinical application. 2018 Vol. 35 (7): 1298-1300 [Abstract] ( 22 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1301 Changes of T Cell Immune Function in Patients with Liver Cancer Treated by Minimally Invasive Interventional Therap YI Ze-jun, WU Jian-ping DOI: 10.3969/j.issn.1671-7171.2018.07.018 【Objective】To study the clinical effect of minimally invasive interventional therapy on hepatocellular carcinoma and its influence on T cell immune function in patients.【Methods】A total of 40 liver cancer patients who treated by transcatheter arterial chemoembolization and 40 patients with liver cancer who treated by radiofrequency ablation in our hospital between January 2014 and December 2017 were categorized group A and group B, respectively. The clinical data of the two groups were analyzed retrospectively, and the clinical efficacy, T cell immune function index, postoperative complications, liver function index, postoperative pain score and quality of life score were compared between the two groups.【Results】In terms of clinical efficacy, there was no significant difference in objective remission rate and total effective rate between the two groups( P > 0.05). Compared to that in group A, the serum ALT level in group B was significantly higher ( P < 0.05). After operation, the CD3+ and CD4/CD8 of the two groups were lower than those before the operation( P < 0.05), while the CD3+ and CD4/CD8 in group B were higher than those in the group A ( P < 0.05). There was no significant difference in the incidence of postoperative complications between the two groups ( P > 0.05). The scores at 8h, 12h, 24h and 48h after operation in group B were lower than those in group A ( P < 0.05). After operation, the quality of life scores in both groups were significantly higher than those before the operation ( P < 0.05), but that in group B was higher than that in group A ( P < 0.05).【Conclusion】The use of radiofrequency ablation in the treatment of liver cancer patients can reduce the interference of interventional therapy on the immune function of T cells and liver function as much as possible on the premise of interventional therapy, which is beneficial to alleviating postoperative pain and improving the quality of life. 2018 Vol. 35 (7): 1301-1303 [Abstract] ( 30 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1304 Comparison between Transcallosal Transchoroidal Approach and Krause Approach to Resect Posterior Third Ventricular and Pineal Region Tumors LIAO Xin-bin, LIU Jing-ping DOI: 10.3969/j.issn.1671-7171.2018.07.019 【Objective】To investigate the surgical outcomes of transcallosal transchoroidal approach and Krause approach to resect posterior third ventricular and pineal region tumors. 【Methods】Retrospective analysis of clinical data of patients with posterior third ventricle and pineal region tumors admitted to our hospital from March 2007 to October 2013 were studied, which included 54 cases of posterior third ventricular and pineal region tumors treated by the Krause approach and 20 cases of posterior third ventricular and pineal region tumors treated by the transcallosal transchoroidal approach. All the patients were assessed by MRI in less than 3 days after operation. 【Results】In the transcallosal transchroidal approach group, 20 patients underwent total resection of the tumor with 1 case (5.00%) coma due to frontal lobe hematoma. There were no deaths during surgery. However, there were 2 cases of postoperative hydrocephalus (10.00%) who underwent ventriculo-peritoneal shunt surgery. In the Krause approach group, 50 cases (92.58%) of posterior third ventricular and pineal region tumors were totally resected and 4 cases (7.4%) underwent subtotal resection, with 2 (3.70%) deaths and 4 (7.41%) comas. There were still 4 cases (7.41%) of hydrocephalus after operation, and endoscopic three-ventricle ostomy (ETV) and ventriculo-peritoneal shunt (VPS) were used.【Conclusion】 Both the transcallosal transchoroidal approach and Krause approach are good choices for pineal region tumors removal. The transcallosal transchoroidal approach is more appropriate for third ventricular tumor, while the Krause approach is more suitable for tumors located in the pineal region. 2018 Vol. 35 (7): 1304-1307 [Abstract] ( 42 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1308 Analysis of Changes of Plasma Lipoprotein a and Related Apolipoproteins in Patients with Coronary Heart Disease LI Zhao-qi, WANG Dong, XIAO Shao-wu DOI: 10.3969/j.issn.1671-7171.2018.07.020 【Objective】To investigate the changes and clinical significance of lipoprotein a [Lp (A)] and ApoA-1,ApoB in patients with coronary heart disease. 【Methods】 Sixty-five patients with coronary heart disease treated in our hospital from January 2016 to April 2017 were retrospectively analyzed. Data (observation group), while 65 healthy volunteers who were examined in our hospital at the same time were classified as control group. The clinical data and laboratory results of all subjects were collected from the inpatient electronic medical record system to collect age, sex, whether or not they were suffering from chronic diseases such as hypertension, diabetes and hyperlipidemia. The plasma levels of Lp(A), ApoA-1, ApoB and ApoB/ApoA-1 were compared between the two groups. The predictive value of the above laboratory indexes for coronary heart disease (CHD) was evaluated by the (ROC) curve of the operating characteristics of the subjects. 【Results】The serum Lp (A), ApoB, ApoB/ ApoA-1 level in the observation group was significantly higher than that in the control group ( P < 0.05), and the serum ApoA-1 level in the observation group was lower than that in the control group, but the difference was not statistically significant ( P > 0.05). The evaluation of ROC curve showed that ApoB/ApoA-1 was the most effective in the diagnosis of coronary heart disease. The AUC (95%CI) of ROC curve was 0.81(0.74~0.89)and 0.78(0.70~0.86). The optimal diagnostic critical value value of Lp(A),ApoB, ApoB/ApoA-1 was 156.4 mg/L, 0.83 g/L ,1.15. Logistic regression analysis showed that Lp(A)> 156.4 mg/L, ApoB> 0.83 g/L, ApoB/ApoA-1> 1.15 were independent risk factors of coronary heart disease.【Conclusions】The high level of Lp(A), ApoB, ApoB/ApoA-1 in patients with coronary heart disease (CHD) is a potential clinical marker for the diagnosis of CHD. Lp(A)> 0.83 g/L and ApoB/ApoA-1> 1.15 are independent risk factors for coronary heart disease. 2018 Vol. 35 (7): 1308-1310 [Abstract] ( 30 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1311 Effect of Vocational Rehabilitation Training on Self-Care Ability and Social Function of Patients with Convalescent Schizophrenia AN Chun, PAN Mei, XIANG Qin, et al DOI: 10.3969/j.issn.1671-7171.2018.07.021 【Objective】To investigate the effect of vocational rehabilitation training on self-care ability and social function of patients with convalescent schizophrenia. 【Methods】A total of 96 cases of patients with convalescent schizophrenia admitted to our hospital from May 2016 to April 2017 were selected as the research subjects and were randomly divided into the observation group and the control group according to the admission time, with 48 cases in each group. Patients in the control group were given routine drug therapy, work, recreational therapy, basic life skills training, etc., while patients in the observation group were given vocational rehabilitation training in addition to activities of the control group. The activity of daily living scale (ADL) was used to assess the self-care ability, and the inpatient psychosis rehabilitation observe scale (IPROS) was used to assess the social function. 【Results】The scores on the physical self-maintenance scale and instrumental self-care ability in observation group were significantly higher than those in control group ( t=5.805~10.299, P < 0.051). The scores of work and recreational therapy, activities of daily living, social skills, daintily sanitation ability, concern/interest, and the total score were significantly higher than those in control group ( t=4.013~8.500, P < 0.05). 【Conclusion】Vocational rehabilitation training can help to enhance the self-care ability and improve social function of patients with convalescent schizophrenia. Research on rehabilitation training programs should be strengthened to give greater effect. 2018 Vol. 35 (7): 1311-1313 [Abstract] ( 39 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1314 Clinical Analysis of 23 Patients with Neonatal Necrotizing Enterocolitis Complicated with Hirschsprung's Disease SU Jia-hong, YANG Liu-cheng, HU Xiao-hua, et al DOI: 10.3969/j.issn.1671-7171.2018.07.022 【Objective】To investigate the clinical features of patients with neonatal necrotizing enterocolitis (NEC) complicated with Hirschsprung's disease (HD). 【Methods】The clinical data of 289 children with NEC who were admitted to Zhongshan Bo'ai Hospital affiliated to Southern Medical University from January 2010 to December 2017 were retrospectively analyzed. Among them, there were 23 cases of NEC combined with HD. The gestational age, birth weight, feeding style, gender, age of onset, clinical manifestations, laboratory findings, and abdominal X-ray findings of children with NEC combined with HD were collected.【Results】A total of 23 NEC patients with HD accounted for 7.95% (23/289) , of the patients, including 17 males and 6 females, with a mean gestational age of 35.6± 3.7 weeks. Patients enrolled in this study ( n =23) were 14 predominantly term infants (60.9%, 14/23) and 9 premature infants. None of the 23 patients had history of asphyxia/hypoxia or delayed meconium excretion. There were 2 patients of Bell stageⅠ, 4 patients of Bell stage Ⅱ and 14 patients of Bell stage Ⅲ, respectively. There were 11 patients with fever and 2 patients with low temperature.All 23 patients had abdominal distention, of whom 21 patients had history of vomiting and 11 patients had gastrointestinal hemorrhage, accounting for 91.3% and 47.8% respectively. There were 9 cases (39.1%) with swollen redness of abdominal wall, 13 cases (56.3%) with abdominal wall tenderness and 11 cases (47.8%) with peristaltic sound disappearance. One patient was found with gas feces ejection during rectum examination. In 23 patients, there were 8 cases (34.8%) with pneumoperitoneum, 6 cases (26.1%)with intestinal wall pneumatosis, 18 cases (78.3%) with intestinal stiffness, 16 cases (69.6%) with intestinal wall thickening, 2 cases(8.7%) with colon dilatation, 16 cases(69.6%) with intestinal obstruction, and 4 cases (17.4%) with hepatic portal venous gas. Treatment and prognosis: Symptoms of 6 patients of Bell stage Ⅰ and stage Ⅱ patients were improved after conservative treatment; 17 children of Bell stage Ⅲ received surgery. In total, 21 cases were cured, 1 case quitted treatment, and 1 case died. 【Conclusion】It is not uncommon for children with NEC to have HD. The presentations and imaging manifestations are not specific. Rectal biopsy is an important means of diagnosis. Early diagnosis is useful for surgical options and prognosis. 2018 Vol. 35 (7): 1314-1316 [Abstract] ( 38 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1317 Effect of the Uterine Parceled Suture in Preventing Postpartum Hemorrhage of Cesarean Section PEI Hai-Yan DOI: 10.3969/j.issn.1671-7171.2018.07.023 【Objective】To investigate the effectiveness and safety of the uterine parceled suture in the treatment of postpartum hemorrhage with cesarean section. 【Methods】A total of 80 cases of postpartum hemorrhage with caesarean section in our hospital from January 2013 to December 2014 were enrolled as the research subjects. According to the random number table method, patients were randomly divided into the observation group and the control group with 40 cases in each group.The control group was given with stuffing gauze to stop bleeding, while the observation group was treated with uterine parceled suture to stop bleeding. The situation of perioperative period, clinical efficacy and postoperative complications were compared between the two groups. 【Results】The operation time, intraoperative bleeding volume, the amount of 24h postoperative vaginal bleeding, and hospitalization time in the observation group were lower than those in the control group ( P < 0.05).The total effective rate in the observation group was 97.50%, which was significantly higher than in the control group 85.55% ( P < 0.05);The postoperative complication rate in the observation group was 5.00%, which was significantly lower than 22.50% in the control group ( P < 0.05). 【Conclusion】Uterine parceled suture in the treatment of cesarean section postpartum hemorrhage is effective.It can shorten the hospitalization time, reduce the incidence of postoperative complications.It is worthy of clinical application. 2018 Vol. 35 (7): 1317-1319 [Abstract] ( 30 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1320 Clinical Efficacy of Two Administrations of Bromocriptine in the Treatment of Female Hyperprolactinemia Infertility XU Xiao-hong, ZHANG Lei, LI Ning, et al DOI: 10.3969/j.issn.1671-7171.2018.07.024 【Objective】To investigate the clinical efficacy of two administrations of bromocriptine in the treatment of female hyperprolactinemia (HPRL) infertility.【Methods】A total of 87 cases of HPRL patients admitted from May 2014 to May 2016 in our hospital were retrospectively divided into control group and observation group according to the way of administration of bromocriptine. The control group was treated with oral bromocriptine treatment while the observation group were treated by vaginal administration of bromocriptine . Clinical symptoms, serum follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), prolactin (PRL) levels, ovulation rate, pregnancy rate, abortion rate and adverse reaction rate after treatment in the two groups were compared. 【Results】The number of patients with rare menstruation, amenorrhea, galactorrhea, hirsutism and headache in two groups after treatment was lower than that before treatment ( P < 0.05). After treatment, the levels of FSH and E2 in two groups were higher than those before treatment, while the levels of LH and PRL were lower than those before treatment ( P < 0.05).However, no significant differences were shown between the two groups ( P > 0.05). There were no significant differences in ovulation rate, pregnancy rate and abortion rate between the two groups ( P > 0.05). The adverse reaction rate in the observation group was lower than that in the control group ( P < 0.05). 【Conclusion】Oral and vaginal administration of bromocriptine are effective in treating female hyperprolactinemia infertility. It can improve the serum sex hormone levels and control the level of serum PRL. However, the incidence of adverse reactions to vaginal administration is low, which is worthy of clinical application. 2018 Vol. 35 (7): 1320-1322 [Abstract] ( 32 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1323 Effects of Different Pre-hospital Emergency Care for Patients with Acute Myocardial Infarction and the Effect on Patients' Satisfaction ZHOU Wei-tian, WEN Jun-jie, LIANG Bo-wen DOI: 10.3969/j.issn.1671-7171.2018.07.025 【Objective】To analyze the effects of different pre-hospital emergency care for acute myocardial infarction(AMI) and its influence on the patients' satisfaction. 【Methods】A total of 140 patients with AMI were randomly divided into two groups, 70 cases in each group. The control group was treated by routine pre-hospital emergency care . The observation group was given treatment first, then transshipment o, and the effect of treatment and satisfaction between the two groups were compared.【Results】The time from onset to admission of the study group was (38.42± 11.35) min, which was significantly longer than that of the control group (16.76± 7.58) min ( P< 0.01).The total effective rate and survival rate of the study group were 98.57%(69/70) and 97.14%(68/70), respectively, which were higher than those of in the control group (85.71%(60/70) and 82.86%(58/70), P < 0.05). All of the vital signs of the study group were significantly better than those of in the control group ( P < 0.05). In addition, the patients' satisfaction score in the study group was significantly higher than that in the control group ( P < 0.05). 【Conclusion】Different methods of pre-hospital emergency care have different effects on patients with AMI. The treatment-first and transportation-later approach can effectively improve the clinical treatment effect and the survival rate of the patients, and it is helpful to improve the patient's satisfaction, and it may be widely used and popularized. 2018 Vol. 35 (7): 1323-1324 [Abstract] ( 38 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1325 Effect of Comprehensive Intervention on Postoperative Infection Prevention in Otolaryngology Patients LUO Hui-xia, HUANG He DOI: 10.3969/j.issn.1671-7171.2018.07.026 【Objective】To investigate the effect of comprehensive intervention on postoperative infection prevention in otolaryngology (ENT) patients. 【Methods】The subjects were selected from 82 cases of otorhinolaryngology patients undergoing elective surgery in our hospital from January 2015 to December 2016.Of them, 41 patients admitted from January 2015 to December 2015 were selected as the control group and 41 patients from January 2016 to December 2016 were treated as the observation group. The control group was given only perioperative routine nursing intervention while the observation group was given comprehensive nursing intervention for the prevention of postoperative otolaryngology infection. The prevention effect of postoperative infection was compared between the two groups. 【Results】The postoperative infection rate in the observation group was 4.88% (2/41), which was significantly lower than that in the control group 26.83% (11/41) ( P < 0.05). There was no significant difference in the number of colonies of preoperative pathogens between the two groups before operation ( P > 0.05).However, the number of colonies of pathogens in the two groups increased at 10 minutes after operation and at the end of surgery. In the observation group, the numbers of colonies of pathogens at 10 min after operation and at the end of surgery were lower than those of the control group at the same time points ( P < 0.05). The average antibiotic use time, hospitalization time and hospitalization cost in the observation group were significantly lower than those in the control group ( P < 0.05). The satisfaction rate of nursing service in the observation group was 95.12% (39/41), which was significantly higher than that in the control group 75.61%, (31/41) ( P < 0.05). 【Conclusion】 The comprehensive nursing intervention for infection prevention in otolaryngology patients can effectively reduce the incidence of postoperative infection, shorten the length of hospital stay, and improve patient satisfaction is high. So it is worth popularizing and applying. 2018 Vol. 35 (7): 1325-1328 [Abstract] ( 24 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1329 Effect of Continual Nursing Intervention Based on Network Platform on Postnatal Maternal Self-care Ability and Parental Behavior of Primipara LUO Fang-fang, ZHANG Shu-lin DOI: 10.3969/j.issn.1671-7171.2018.07.027 【Objective】To explore the effect of continual nursing intervention based on network platform on postnatal maternal self-care ability and parental behavior, and to provide reference for extending the continuity nursing intervention methods for primipara. 【Methods】A total of 132 patients who were successfully discharged from our hospital between July 2015 to June 2016 were selected as study subjects. Patients were randomly divided into the treatment group and the control group by random number table method, with 66 cases in each group. The control group was given routine discharge guidance. The treatment group was given continual nursing intervention based on network platform. Through 4 months of follow-up, the ability of self-care and nursery effects were compared between the two groups. 【Results】The scores of primipara's psychological adjustment, puerperal health, abnormal symptoms, postpartum diet, neonatal feeding were significantly higher in the treatment group than in the control group ( P < 0.05). Neonatal massage, neonatal bathing, correct neonatal umbilical care, and breastfeeding rate were significantly higher in the observation group than in the control group, while the neonatal prevalence rate was significantly lower than the control group ( P < 0.05). 【Conclusion】Continual nursing intervention based on network platform can help improve postnatal maternal self-care ability, enhance the effectiveness of neonatal care and breast-feeding, and reduce the prevalence of neonatal diseases. 2018 Vol. 35 (7): 1329-1331 [Abstract] ( 30 ) HTML (1 KB)  PDF  (0 KB)  ( 1 ) 1332 Effect of Serum Inflammatory Factors on Restenosis after PCI in AMI Patients Wu Jun DOI: 10.3969/j.issn.1671-7171.2018.07.028 【Objective】 To investigate the effect of changes of serum inflammatory factors on restenosis after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI). 【Methods】 The clinical data of 120 patients with AMI from March 2015 to March 2016 were analyzed retrospectively. According to the results of coronary angiography, the patients were divided into restenosis group ( n =41) and non-restenosis group ( n =79). The serum levels of vascular endothelial growth factor (VEGF), hypersensitive C-reactive protein (hs-CRP), pregnancy-associated protein A (PAPP-A), matrix metalloproteinase-9 (MMP-9) and interleukin-10 (IL-10) were measured and compared between the two groups. 【Results】The levels of serum total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) in the restenosis group were significantly higher than those in the non restenosis group. The serum high density lipoprotein cholesterol (HDL-C) level was significantly lower in the restenosis group than in non restenosis group ( P < 0 05). There was no significant difference in the serum levels of VEGF hs-CRP PAPP-AMP 9 IL-10 between the restenosis group and the non-restenosis group before operation ( P > 0.05), and on the third and 7th day after operation, the serum levels of VEGF hs-CRP PAPP-AMP 9 IL-10 in the restenosis group were significantly higher than those in the non-restenosis group ( P < 0.05). 【Conclusion】The level of IL-10 in serum VEGF, hs-CRP, PAPP-A,MMP- 9 and IL-10 in patients with AMI after PCI is increased, which has a certain effect on the occurrence of restenosis. 2018 Vol. 35 (7): 1332-1334 [Abstract] ( 27 ) HTML (1 KB)  PDF  (0 KB)  ( 1 )

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