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Quick Search     Adv Search 2016 Vol. 33, No. 11 Published: 2016-11-21 Article          Article 2081 Influence of Hydrotalcite on Inflammatory Factors and Gastrointestinal Kinetics on Model Rats with Reflux Gastritis LI Xing-hong, ZHAO Liang DOI: 10.3969/j.issn.1671-7171.2016.11.001 【Objective】To investigate the influence of hydrotalcite (a reagent like aluminum magnesium carbonate) on inflammatory factors and gastrointestinal kinetics of model rats with reflux gastritis. 【Methods】A total of 36 SPF level Wistar rats were selected as the objects of study and randomly divided into the normal group, the model group, and the hydrotalcite group, with 12 rats in each group. Reflux gastritis model was established in both the model group and the hydrotalcite group. Rats in the hydrotalcite group were given 1ml hydrotalcite suspension for gavage administration, while rats in the normal group and the model group were given the equivalent amount of normal saline for gavage administration. The weight growth, esophageal coefficient, and score of mucosal injury of rats in the three groups were observed, and the inflammatory factors of mucosal tissues and serum gastric dynamics index were tested. 【Results】The weight growth of the model group was significantly lower than the normal group, and the esophageal coefficient and score of mucosal injury were significantly higher than those of the normal group (t=10.543, 13.247, 19.611,P<0.05). the weight growth of the hydrotalcite group was significantly higher than the model group, and the esophageal coefficient and score of mucosal injury were significantly lower than those of the model group (t=6.954, 7.562, 8.028,P<0.05). The tumor necrosis factor alpha (TNF-α), interleukin-8 (IL-8), and intercellular adhesion molecule 1(ICAM-1) of the mucosal tissues of the model group were significantly higher than in the normal group (t=3.605, 10.709, 6.603,P<0.05). The TNF-α, IL-8, and ICAM-1 of the mucosal tissues of the hydrotalcite group were significantly lower than the model group (t=2.242, 7.773, 4.864,P<0.05). The contents of serum gastrin (GAS) and motilin (MTL) of the model group were significantly lower than those of the normal group (t=3.934, 4.785,P<0.05); the contents of serum GAS and MTL of the hydrotalcite group were significantly higher than the model group (t=3.173, 3.985,P<0.05). 【Conclusion】Hydrotalcite is conductive to lowering the content of inflammatory factors of mucosal tissues, reducing the gastric mucosal damage and improving the gastrointestinal function in model rats with reflux gastritis. 2016 Vol. 33 (11): 2081-2084,2087 [Abstract] ( 197 ) HTML (1 KB)  PDF (1273 KB)  ( 131 ) 2084 Effect of Extracellular Matrix Expression on Paxillin and Vinculin in Cultured Vascular Smooth Muscle Cells HE Xie-ling, CAI Wei-jun, LIU Min,et al DOI: 10.3969/j.issn.1671-7171.2016.11.002 【Objective】To investigate the expression of the extracellular matrix (ECM) on focal adhesion (FAs) protein paxillin and vinculin in cultured vascular smooth muscle cells (SMCs).【Methods】 Rat aortic SMCs of fourth～sixth generation were grown on coverslips coated with fibronectin ( FN) or laminin (LN),or planted on Matrigel for cultivation. The expression of paxillin and vinculin was detected by confocal immunofluorescence technique, and was demostrated by the double fluorescence staining of the FAs vinculin/F-actin and paxillin/F-actin.【Results】The vinculin expression planted on FN was the lowest, and the LN was the second, and the highest expression was in Matrigel ; the cytoplasm of the vinculin on FN was more distributed ,but less on FAs; and vinculin, which grew on the LN matrix and the Matrigel, were more localized in the FAs, but less distributed in the cytoplasm. The fluorescence intensity of Vinculin was (64.72±7.18)AU/μm2,(89.82±5.11)AU/μm2,(117.19±16.99)AU/μm2 respectively in FN, LN and Matrigel, which were in turn increased, and there was statistical significance between the groups (P<0.05).The paxillin grown on FN was the highest, while that on the LN came the second, and that on Matrigel showed the lowest expression; Paxillin in Matrigel was mainly distributed in FAs, and that on FN also got a higher expression in the cytoplasm, except for that distributed on FAs. The fluorescence intensity of Paxillin was(129.87±10.22)AU/μm2,(86.59±9.90)AU/μm2,(56.32±7.54)AU/μm2,respectively in FN, LN and Matrigel, which were in turn decreased, and there was statistical significance between the groups (P<0.05).【Conclusion】Different ECM components have effect on the expression of FAs molecule: FN can up regulate the expression of paxillin and down regulate the expression of vinculin; while the LN and Matrigel can increase the expression of vinculin and decrease the expression of paxillin. 2016 Vol. 33 (11): 2084-2087 [Abstract] ( 114 ) HTML (1 KB)  PDF (2680 KB)  ( 61 ) 2088 Clinical Efficacy and Safety of Butylphthalide Combined with Vinpocetine in the Treatment of Posterior Circulation Ischemic Vertigo Caused by the Dominant Vertebral Artery GONG Jian-zu, CHENG Wei DOI: 10.3969/j.issn.1671-7171.2016.11.003 【Objective】To evaluate the efficacy and safety of butylphthalide combined with vinpocetine in the treatment of Posterior Circulation Ischemic Vertigo (PCIV) caused by the dominant vertebral artery.【Methods】Eighty-two cases of PCIV patients caused by the dominant vertebral artery were randomly divided into two groups: the control group (n=41) received vinpocetine therapy, and the experimental group (n=41) received butylphthalide combined with vinpocetine therapy. The clinical efficacy and side effects of the two groups were compared. 【Results】The cure rate and total effective rate of patients in the experimental group was 48.78% and 92.68%, respectively, and were significantly higher than for patients in the control group 29.27% and 80.49%, respectively. After treatment, the Vm of the bilateral vertebral artery (LVA, RVA), of the bilateral posterior cerebral artery (LPCA, RPCA), and of the basilar artery (BA) was significantly higher in the experimental group than in the control group. The hemorheology indexes (WBV, PV, and PAI) were significantly lower in the experimental group than in the control group, the differences between the two groups being statistically significant (P<0.05). 【Conclusion】It's safe and effective to use the combination of of butylphthalide and vinpocetine for treatment of PCIV caused by the dominant vertebral artery. The combined treatment can effectively improve the hemorheological and posterior circulation ischemic symptoms of patients. 2016 Vol. 33 (11): 2088-2091 [Abstract] ( 60 ) HTML (1 KB)  PDF (1268 KB)  ( 49 ) 2091 Analysis of Influencing Factors on Neonatal Body Weight LI Chen-bo, WANG Xi-ning, SHEN Jiang-fang,et al DOI: 10.3969/j.issn.1671-7171.2016.11.004 【Objective】 To explore the influencing factors of neonatal body weight. 【Methods】Retrospective analysis of clinical data of 6,489 pregnant women in our hospital from January 2012 to December 2014 was conducted. According to the newborn body weight, the newborn were divided into the low body mass, the normal body weight and the giant baby. The univariate and multivariate analysis of factors influencing the quality of neonates were performed.【Results】 Among 6,489 cases of pregnant women, 634 cases suffered from hypertensive disorder complicating pregnancy (HDCP) ,the incidence was 9.77%(634/6489). Logistic multivariate regression analysis showed that: HDCP, preterm labor, pre pregnancy BMI<18.5 kg/m2, weight gain during pregnancy <12 kg and smoking were risk factors for neonatal low body weight. HDCP, pre pregnancy BMI > 24 kg/m2 and weight gain during pregnancy >16 kg were risk factors of macrosomia.【Conclusion】 HDCP, premature birth, BMI before pregnancy, change of body weight and smoking are the factors influencing the quality of neonatal body. 2016 Vol. 33 (11): 2091-2095 [Abstract] ( 102 ) HTML (1 KB)  PDF (1277 KB)  ( 38 ) 2095 Incidence and Impact Factors of Sputum Crust Obstruction in ICU Patients Undergoing Artificial Airway LIANG Juan, HU Xue-hui, SUN Xin,et al DOI: 10.3969/j.issn.1671-7171.2016.11.005 【Objective】 To investigate the incidence and impact factors of sputum crust obstruction in ICU patients underwent artificial airway. 【Methods】 A total of 621 ICU patients underwent artificial airway over 24h in the hospital from January 2015 to December 2015 was selected. Patients were treated with primary disease treatment and clinical standard airway care so as to compare the incidence rate of sputum crust in patients with artificial airway under tracheal intubation and tracheotomy. Multivariate logistic regression analysis was used to confirm the risk factors for the occurrence of intra sputum crust in artificial airway. 【Results】 The incidence of sputum crust obstruction in 621 ICU patients underwent artificial airway was 9.02% (56/621). The incidence of sputum crust obstruction in endotracheal intubation and tracheotomy was 8.49%(46/542), 12.66% (10/79) respectively, there was no statistical difference (χ2=1.4621,P=0.23). Patients with severe traumatic brain injury and COPD showed higher incidence of sputum crust obstruction as 12.39% and 9.60%. Cough reflex disappearance, complicated pulmonary infection, mis-aspiration, long-time piped , no effective airway humidification and airway bleeding were independent risk factors for the blockage of sputum in artificial airway(P＜0.05).【Conclusion】 Sputum crust obstruction is a common clinical complication in ICU patients underwent artificial airway. Patients with severe traumatic brain injury and COPD are needed to strengthen preventive care. Effective prevention of risk factors and nursing help to reduce the incidence of sputum crust obstruction in ICU patients undergoing artificial airway. 2016 Vol. 33 (11): 2095-2098 [Abstract] ( 234 ) HTML (1 KB)  PDF (1287 KB)  ( 125 ) 2099 Clinical Effect of Azithromycin Combined with Doxycycline in Treatment of Nongonococcal Cervicitis SONG DOI: 10.3969/j.issn.1671-7171.2016.11.006 【Objective】 To observe and discuss the clinical effect of Azithromycin combined with Doxycycline in treatment of nongonococcal cervicitis.【Methods】 Data had been collected from 96 nongonococcal cervicitis patients in our hospital from January 2013 to December 2015. All patients were randomly divided into three groups: Azithromycin group, Doxycycline group and Azithromycin combined Doxycycline group, 32 cases in each. 2 weeks after the treatment, clinical efficacy and the negative rate of Chlamydia trachomatis (CT) and Ureaplasma urealyticum (UU) of the three groups of patients were observed.【Results】 The total effective rate of the combined group was 96.87% (31/32), significantly higher than that of the Azithromycin group 87.50%(28/32) and the Doxycycline group, 90.63% (29/32), the difference was statistically significant (P<0.05); the negative rate of CT infection, UU infection, and mixed infection of the above two in the combined group reached 94.12% (16/17), 90% (9/10) and 100% , which were significantly higher than those of Azithromycin Group and the Doxycycline Group (P<0.05).【Conclusion】 The curative effect of Azithromycin combined with Doxycycline in the treatment of non gonococcal cervicitis is significant, it is worthy of clinical application. 2016 Vol. 33 (11): 2099-2101 [Abstract] ( 93 ) HTML (1 KB)  PDF (1244 KB)  ( 88 ) 2101 Effect of Path Management on Psychological State of Patients Underwent Microsurgical operation of Petroclival Meningioma HU Yang-qiong, LIU Yue-hui, LIU Wen-zhuo,et al DOI: 10.3969/j.issn.1671-7171.2016.11.007 【Objective】To explore the effect of path management on the psychological state of patients underwent microsurgical operation of petroclival meningioma.【Methods】 One hundred and two patients underwent microsurgical operation of petroclival meningioma in our hospital from April 2013 to March 2016 were randomly divided into the control group and the observation group with 51 cases in each. The control group was treated with the routine nursing mode for nursing, while the observation group received the clinical path nursing. The self rating Depression Scale (SDS) and self rating Anxiety Scale (SAS) were used for psychological state evaluation in the two groups of patients at the time of admission and before discharge, and the average length of hospital stay and patients' satisfaction with nursing work in the two groups were compared.【Results 】The SDS, SAS score of the observation group were significantly lower than those of the control group, and the hospital stay was also less than that of the control group, but the satisfaction was higher than the control group, the difference between the two groups was statistically significant (P<0.05).【Conclusions】 The application of clinical path nursing management for patients with petroclival meningioma undergoing microsurgical treatment can relieve the adverse psychological reaction , shorten the hospitalization time, improve patient satisfaction, it is worth promoting in clinical practice. 2016 Vol. 33 (11): 2101-2103 [Abstract] ( 53 ) HTML (1 KB)  PDF (1264 KB)  ( 37 ) 2104 A Clinical Study on Vermilion Reconstruction of Bilateral Cleft Lip Using A New Trapezoidal Flap YANG DOI: 10.3969/j.issn.1671-7171.2016.11.008 【Objective】To evaluate the efficacy of vermilion reconstruction of the bilateral cleft lip using a new trapezoidal flap.【Methods】This study was conducted on 96 patients with bilateral cleft lip who came to our hospital from January 2008 to January 2014. These patients were randomly divided into group 1 and group 2; the 52 cases in group 1 underwent the modified trapezoidal flap for vermilion reconstruction while the 44 cases in group 2 were treated with the straight line closure. The shape of vermilion, whistle deformities, and Cupid's bow deformities were observed postoperatively with follow-up appointments at 7 days and 1~2 years. 【Results】At the time of the follow-up 1 to 2 years postoperative, 90 cases of children's wounds were healed, 5 cases that started with a large gap and had late treatment failed to be corrected and had postoperative high wound tension and resulting wound infection, 1 case showed nasal rupture after surgery with bilateral upper lip trapezoidal mucosal myocutaneous flap. Three cases of bilateral mixed cleft lip who undergone bilateral upper lip trapezoidal flap surgery had some asymmetrical deformities after operation. Within 1 ~ 2 years, the incidence of whistle deformity and Cupid's bow deformities in the observation group was significantly lower than that in the control group(P<0.05), but there was no significant difference between the two groups in terms of upper lip tension or length(P>0.05).【Conclusion】Vermilion reconstruction of bilateral cleft lips using the new trapezoidal flap surgery is a useful method with a high success rate, especially for the reconstruction of the vermilion, labial arch, and vermilion tubercle. Its incidence of postoperative deformities is lower than the straight suture method and is worthy of clinical application. 2016 Vol. 33 (11): 2104-2106 [Abstract] ( 66 ) HTML (1 KB)  PDF (1937 KB)  ( 44 ) 2107 Clinical Study on Bevacizumab Combined with FOLFOX4 Chemotherapy Regimen in the Treatment of Advanced Rectal Cancer HU Chun-xia, JIANG Wei-mei, LI Xiao-min,et al DOI: 10.3969/j.issn.1671-7171.2016.11.009 【Objective】To observe the clinical effect of bevacizumab combined with 5-fluorouracil (5-Fu), leucovorin (LV) and oxaliplatin (L-OHP) (FOLFOX4) chemotherapy regimen in the treatment of advanced rectal cancer. 【Methods】Eighty-six patients with advanced rectal cancer who were admitted to our hospital were selected as study subjects. According to order of hospitalization, the subjects were numbered and were randomized into a control group and an observation group, with 43 cases in each group. Both groups received FOLFOX4 first-line chemotherapy. The observation group was treated with bevacizumab in addition to this. The treatment effects,toxicity and survival rate were compared between the two groups. Both groups were followed up for 2 years. The survival rate was recorded and the quality of life was evaluated by European organization for research and treatment of cancer quality of life questionnaire (EORTC QLC-CR37 ). 【Results】① The total response rate in the observation group was higher than that in the control group (P<0.05). ② There was no significant difference in the incidence of toxic and side effects between the two groups (P>0.05). ③ After 2 years of follow-up, the overall survival rate of the observation group was higher than that of the control group (P<0.05). ④ After 3, 6, 12 and 24 months of treatment, the quality of life scores of both groups decreased (P<0.05), and the decrease in the observation group was greater than that in the control group (P<0.05). 【Conclusion】The application of bevacizumab combined with FOLFOX4 chemotherapy in treatment of advanced rectal cancer has a high total response rate, can improve the 2-year survival rate of patients and can optimize the quality of life. 2016 Vol. 33 (11): 2107-2110 [Abstract] ( 66 ) HTML (1 KB)  PDF (1267 KB)  ( 66 ) 2110 Clinical Study of Glutamine on Neonatal HIE LEI Juan-juan DOI: 10.3969/j.issn.1671-7171.2016.11.010 【Objective】To study the protection effect of glutamine on cerebral hypoxia of neonates.【Methods】Eighty neonates in our hospital with HIE from May 2014 to February 2015 were chosen as study objects, all neonates were divided into the treatment group(Group A) and the control group . According to the different dosage ,the former was re-divided into three sub-groups : A1[ glutamine 50mg/(kg·d)], A2[glutamine 75mg/(kg·d)] and A3 [glutamine 100mg/(kg·d)], 20 cases in each. The treatment effect , the Neonatal Behavioral Neurological Assessment (NABA)before and after treatment, the Neuroglobin (NGB) and the neuron-specific enolase(NSE)were compared among different groups.【Results】The effect rate of group A1 was 65.00%, A2 was 75.00%, A3 was 90.00%, the Group B was 50.00%, the difference had statistical significance(P＜0.05). After treatment, the NABA scores of different groups were increased significantly(P＜0.05), and the NABA had significant difference among different groups(P＜0.05). Before treatment, NGB and NSE had no significant difference among different groups(P＞0.05); 3d and 7d after the treatment, the NGB and NSE of neonates with HIE decreased significantly(P＜0.05), and the NGB and NSE after treatment had significant difference among the groups statistically(P＜0.05). The dose of 100 mg/ (kg·d) glutamine had the best clinical efficacy.【Conclusion】Glutamine can improve the stability of the membrane of neurons, which can protect the brain from hypoxia, the dose of 100 mg/ (kg·d) glutamine has the best clinical efficacy. 2016 Vol. 33 (11): 2110-2112 [Abstract] ( 74 ) HTML (1 KB)  PDF (1271 KB)  ( 34 ) 2113 Study on the Relationship Between AMH and PCOS in Infertile Patients with Ovulation LI Xiao-li, XUE Juan DOI: 10.3969/j.issn.1671-7171.2016.11.011 【Objective】To analyze the relationship between Anti-Mullerian hormone (AMH) and polycystic ovary syndrome (PCOS) in infertile patients with ovulation. 【Methods】A total of 50 cases of patients with PCOS were observed. At the same time, 50 healthy adult women were selected as the control group. The levels of AMH, FSH and LH were detected in the two groups. The differences in AMH levels in follicular fluid between the two groups were compared as well. Further the levels of AMH, FSH and LH were observed in PCOS patients with and without ovulation. 【Results】In the PCOS group, the serum levels of AMH and FSH were significantly higher than those of the control group, while the level of LH was significantly higher than the control group; the difference was statistically significant (P<0.05). M2 follicular fluid AMH and FSH levels were significantly higher than M1 follicular fluid levels, while LH level was significantly lower than that of M1 follicular fluid, and the difference was statistically significant (P<0.05). The levels of AMH and FSH were significantly lower in the PCOS infertility group without ovulation than those in the PCOS infertility patients with ovulation, while the LH level was significantly higher in the patients with ovulation; the difference was statistically significant (P<0.05). 【Conclusion】The level of AMH in patients with PCOS infertility is high, and the AMH level of PCOS patients without ovulation is even higher. This can be used as an indicator for clinical monitoring of PCOS infertility patients with ovulation. 2016 Vol. 33 (11): 2113-2115 [Abstract] ( 132 ) HTML (1 KB)  PDF (1271 KB)  ( 169 ) 2116 Correlation Study on Serum PCSK9 and Carotid Atherosclerosis in Patients with Primary Hypertension YANG Wei, TENG Lin, DING Jia-wang, et al DOI: 10.3969/j.issn.1671-7171.2016.11.012 【Objective】 To investigate the correlation between serum proprotein convertase subtilisin/kexin type 9 (PCSK9) and carotid atherosclerosis in primary hypertension patients. 【Methods】 320 primary hypertension patients were divided into non-carotid atherosclerosis (NCAS) group and carotid atherosclerosis (CAS) group according to CIMT. Body mass index(BMI), blood pressure, blood glucose, blood lipid and serum PCSK9 were measured. logistic multiple regression was used to analyze the correlative factors of serum PCSK-9 level and CIMT .【Results】 The levels of serum PCSK-9 in the CAS group (366.9±72.3) mg/L were significantly higher than that of the NCAS group (280.2±61.4) mg/L. The difference was statistically significant (P<0.05). Logistic multivariate regression analysis revealed that serum PCSK9 was the independent risk factor of carotid atherosclerosis in primary hypertension patients.【Conclusion】The level of serum PCSK-9 is positively correlated with CIMT in patients with primary hypertension, it could be an independent risk factor for atherosclerotic disease. 2016 Vol. 33 (11): 2116-2118 [Abstract] ( 67 ) HTML (1 KB)  PDF (1271 KB)  ( 47 ) 2119 Clinical Effects of Dexmedetomidine with Propofol in Painless Colonoscopy LIU Xiao-mei, QIN Tao DOI: 10.3969/j.issn.1671-7171.2016.11.013 【Objective】To observe the clinical applications and effects of dexmedetomidine with propofol in painless colonoscopy. 【Methods】One hundred painless colonoscopy patients in our hospital were chosen as our study subjects and, according to the prescribed anesthesia program, were divided into the control group (n=50) and observation group (n=50). Patients in the control group were given propofol in conjunction with sufentanil, while the patients in the observation group were given dexmedetomidine with propofol. The anesthetic effects and safety were compared between the two groups.【Results】 The surgery time, recovery time, and hospital stay were significantly shorter in the observation group than in the control group (P<0.05). The propofol dosage given in the observation group was much less than the dosage given to the control group (P<0.05). The preoperative VAS scores, however, were not statistically different (P>0.05). At times 0.5h, 4h, and 8h postoperation, the VAS scores were significantly lower than in the control group (P<0.05). The rate of postoperative complications in the observation group was 8.0%, significantly lower than the 24.0% rate in the control group (P<0.05). 【Conclusion】 Compared with the use of propofol and sufentanil anesthesia in painless colonoscopy, propofol with dexmedetomidine anesthesia has a superior anesthetic effect and greater safety. Therefore it is worthy for wide applications. 2016 Vol. 33 (11): 2119-2121,2124 [Abstract] ( 93 ) HTML (1 KB)  PDF (1246 KB)  ( 36 ) 2121 Value of Serum Cystatin C (Cys C) Level in Evaluation of Cardiac and Renal Function Impairment of Patients with Primary Hypertension GAO Er-xiang DOI: 10.3969/j.issn.1671-7171.2016.11.014 【Objective】To investigate the value of Serum Cystatin C (Cys C) level in the evaluation of cardiac and renal function impairment of patients with primary hypertension. 【Methods】 A total of 186 patients with primary hypertension from January 2011 to September 2014 were selected and divided into the complicated group with cardiac and renal function impairment (group A,n=63) and the non complicated group (group B,n=123),80 healthy adults who received healthy examination were selected as the control group over the same period of time. Gender, age, serum Cys C levels and other clinical indicators were compared among three groups. Simple linear correlation and multiple linear regression analysis were performed to investigate the relationship between serum Cys C levels and other clinical indicators in patients with primary hypertension. The area under receiver operating characteristic (ROC) curve was used to assess the diagnostic value of serum Cys C levels and other clinical indicators in patients with renal impairment. 【Results】 There were significant differences in systolic blood pressure (SBP), diastolic blood pressure (DBP), Cys C, triglyceride (TG), high density lipoprotein cholesterol (HDL-C), blood urea nitrogen (BUN), serum creatinine (Scr), glomerular filtration rate (GFR), micro urinary albumin (mALB), left ventricular ejection fraction (LVEF), left ventricular mass index (LVMI) among three groups (P＜0.05). Serum Cys C level was positively correlated with Scr, mALB, LVMI, and negatively correlated with GFR, LVEF (P＜0.05). The area under ROC curve of Cys C, BUN, Scr, mALB were respectively 0.75, 0.673, 0.688, 0.620. 【Conclusion】 Serum Cys C levels were significantly increased in patients with primary hypertension complicated with cardiac and renal dysfunction. Thus, Serum Cys C level could be used as one of the indexes for evaluating cardiac and renal impairment. 2016 Vol. 33 (11): 2121-2124 [Abstract] ( 94 ) HTML (1 KB)  PDF (1409 KB)  ( 36 ) 2125 Sevoflurane for Laparoscopic Cholecystectomy in Elderly Patients with Inflammatory Reaction on Respiratory Function and Operative Effect Analysis ZHU Hong-wei, LIU Ying, ZHU Jian-jun DOI: 10.3969/j.issn.1671-7171.2016.11.015 【Objective】To investigate the effect of sevoflurane on elderly laparoscopic gallbladder resection (LC) perioperative inflammatory reaction and respiratory dynamic function effect. 【Methods】One hundred and thirty cases of elderly patients taking LC surgical were retrospectively analyzed. The sample set included 69 patients who used sevoflurane anesthesia (sevoflurane group) and 61 patients who used propofol anesthesia (propofol group). Respiratory function index like tidal volume (VT), airway pressure (Paw), peak airway pressure (Ppeak), airway pressure (Pplat) and chest compliance (Compl) were measured at different time points T1 (before anesthesia), T2(after pneumoperitoneum), T3(30 minutes after surgery) and T4(pneumoperitoneum ending). The peri- and post-operative serum inflammatory factor levels (IL-6, TNF-α,IL-10 and CRP) were monitored and compared between the two groups. 【Results】At T1 and T4, the VT, Paw, Ppeak, Pplat, and Compl levels were not statistically different between the sevoflurane and propofol group patients (P>0.05). At T2 and T3, the VT and Compl values were significantly higher in the sevoflurane group than in the propfol group (P<0.05). The Paw value, however, was lower in the sevoflurane group than in the propofol group (P<0.05). Before induction of anesthesia, the IL-6, TNF-α, IL-10, and CRP level were not significantly different between the sevoflurane group and the propofol group (P>0.05). Twenty four hours after operation, the IL-6, TNF-α, IL-10, and C-reactive protein (CRP) levels significantly lower in the sevoflurane group than in the propofol group (P<0.05). 【Conclusion】Sevoflurane has little effect on the elderly LC perioperative respiratory function, however, it does reduce inflammation after operation. 2016 Vol. 33 (11): 2125-2127 [Abstract] ( 52 ) HTML (1 KB)  PDF (1273 KB)  ( 38 ) 2128 Expression of miRNA-145 in Patients with Liver Cancer Induced by Hepatitis B Liver Cirrhosis and Its Relationship with Prognosis YUAN Dong-hong, WANG Fang, TAN Yu-e ,et al DOI: 10.3969/j.issn.1671-7171.2016.11.016 【Objective】To study the expression of cancer tissue miRNA-145 in patients with liver cancer induced by Hepatitis B liver cirrhosis and its relationship with prognosis.【Methods】Seventy-four patients with liver cancer induced by hepatitis B cirrhosis who were admitted in our hospital between January 2009 and January 2012 were selected as the study objects. Cancer tissue specimens were collected from all patients during operation. The expression of miRNA-145 in tumor tissues, the real-time quantitative RT-PCR and cell proliferation were detected, and cell invasion assay was performed. According to miRNA-145 concentration , 50 nmol/L, 100 nmol/L and 150 nmol/L were sub-divided , and the control group was treated with liposome. The effect of miRNA-145 expression and its ability on proliferation of tumor cells, the impact of invasion and metastasis in patients with liver cancer induced by Hepatitis B liver cirrhosis and their relationships with prognosis were investigated and concluded.【Results】The expression levels of cancer tissues and miRNA-145 in Human hepatocellular carcinoma HepG2 cell line were higher than those in normal tissues, the difference was statistically significant (P<0.05). There was no significant difference in the relative proliferation (D490) in each group in 24 h (P>0.05); in 48h and 72h, the cell relative proliferation (D490) of miRNA-145 transfection in different concentration groups was lower than that in the liposome treated group, and the difference was statistically significant (P<0.05). The number of tumor cells through the cell membrane of the experimental group was (0.29±0.05),relatively lower than that of the liposome treated group(0.36±0.12), the difference was statistically significant (P<0.05). The survival time of patients with higher expression of miRNA-145 was longer than that in the lower expression group, and the difference was statistically significant (P<0.05).【Conclusion】The expression of miRNA145 can inhibit tumor proliferation, control tumor progression, reduce invasion and metastasis of tumor cells, and promote apoptosis of tumor cells, thus it is able to prolong the survival time of patients with liver cancer. It is worth clinical in-depth study. 2016 Vol. 33 (11): 2128-2130 [Abstract] ( 102 ) HTML (1 KB)  PDF (1273 KB)  ( 93 ) 2131 Clinical Effect and Follow-up Analysis of Different Surgical Methods in the Treatment of Varicocele ZHANG Peng-jie, YANG Fan, REN Wei,et al DOI: 10.3969/j.issn.1671-7171.2016.11.017 【Objective】To compare the clinical effect and follow-up results of different surgical methods in the treatment of varicocele. 【Methods】 Eighty-eight patients with varicocele treated in the department of urinary surgery in our hospital between January 2013 and June 2015 were selected as subjects. According to the random number table, they were divided into group A (n=46) and group B (n=42). Group A underwent low ligation of spermatic vein under the microscope while group B underwent high ligation of spermatic vein. The operation time, length of hospital stay, incidence of postoperative complications, total effective rate, recurrence rate and atrophy rate 1 year postoperatively were compared between the two groups. 【Results】The operation time of group A was longer than that of group B while the length of hospital stay was shorter than that of group B (P<0.05). The incidence rates of epididymitis, hydrocele, scrotal edema and other complications in group A (2.2%, 2.2%, 4.3%) were lower than those in group B. The total response rate in group A (97.8%) was higher than that in group B (83.3%) (P<0.05). At the end of follow-up, there was no recurrence found in group A group; the recurrence rate was lower than that in group B [9.7% (4/41)]. The atrophy rate [2.2% (1/45)] in group A was lower than that in group B [14.3% (6/41)](P<0.05). 【Conclusion】The application of low ligation of spermatic vein under the microscope in the treatment of varicocele can effectively protect the testicular artery and lymphatic tube, which is conductive to reducing postoperative complications, recurrence rate and testicular atrophy rate so that patients can recover quickly. It is of high clinical application value. 2016 Vol. 33 (11): 2131-2133 [Abstract] ( 75 ) HTML (1 KB)  PDF (1267 KB)  ( 48 ) 2134 Analysis of the Anesthesia Effect of Seven Sevoflurane in the Operation of Children with low Body Mass QIU Zheng-guo, HAN Li-feng, CHEN Bo DOI: 10.3969/j.issn.1671-7171.2016.11.018 【Objective】To investigate the anesthetic effect of seven sevoflurane in children with low body mass. 【Methods】A total of 92 cases of low-weight children who were undergoing abdominal surgery were divided using a random number table into a sevoflurane group and a ketamine group, with 46 cases in each group. In the sevoflurane group, 3% sevoflurane was used for inhalation anesthesia for the abdominal surgery. The inhalation concentration increased by 1% for each three breaths, with a maximum control of 5%. In the ketamine group, patients received 5mg / kg ketamine through intravenous anesthesia. The efficacy and safety of the two methods of anesthesia were compared. 【Results】The time of disappearance of eyelash reflex, pain disappearance time, recovery time and postoperative VAS scores were significantly lower in the sevoflurane group than in the ketamine group; the differences were statistically significant (P<0.05). The fluctuations in MAP, heart rate (HR) and oxygen saturation (SpO2) during surgery and post-operation were more obvious than in the ketamine group than in the sevoflurane group; the differences were statistically significant (P<0.05). The rate of adverse reactions in the sevoflurane group was 6.52%, significantly lower than the rate of 21.74% in the ketamine group (P<0.05). 【Conclusion】 Seven sevoflurane in children with low body mass has the advantages of quick onset of anesthesia, little effect on hemodynamics and low incidence of adverse reactions after operation. 2016 Vol. 33 (11): 2134-2136,2139 [Abstract] ( 54 ) HTML (1 KB)  PDF (1245 KB)  ( 29 ) 2136 Study on the Influence of Bifidobacterium Quadruplex Combined with Oryzanol on Serum Levels of TNF-α、IL-6 in Female Patients with Irritable Bowel Syndrome ZENG Wen DOI: 10.3969/j.issn.1671-7171.2016.11.019 【Objective】To investigate the effect of bifidobacterium quadruplex living bacterium combined with oryzanol in the treatment of irritable bowel syndrome and its influence on serum levels of TNF- alpha and IL-6. 【Methods】A total of 86 cases of patients with irritable bowel syndrome were randomly divided into a control group and an observation group, with n=43 cases in each group. The control group was given routine treatment, while the observation group was given treatment by bifidobacterium quadruple living bacterium combined with oryzanol. 【Results】 The total effective rate of the observation group was higher than that of the control group (95.35% vs 72.09%); the difference had statistical significance (P<0.01). After the treatment, the symptom severity score and frequency of symptoms score of the observation group were lower than of the control group; there was a statistically significant difference (P<0.01). After treatment, the HAMD score (10.41 ± 2.50) points, HAMA score (10.24 ± 2.68) points of the observation group were lower than HAMD (12.92 ± 3.16) score points and HAMA score (12.63 ± 3.35) points of the control group, and there was a statistically significant difference (P<0.01). After treatment, the serum levels of TNF-α (29.72 ± 11.75) pg/mL, IL-6 (11.23 ± 3.15) ng/ L of the observation group were lower than the serum levels of TNF-α (43.56 ± 12.47) pg/mL, IL-6 (17.91 ± 4.17) ng/L of the control group; the differences had statistical significance (P<0.01). 【Conclusion】The curative effect of the bifidobacterium quadruplex living bacterium combined with oryzanol in the treatment of irritable bowel syndrome was good; it can effectively improve the gastrointestinal function and the serum levels of TNF-α and IL-6 to improve the quality of life. 2016 Vol. 33 (11): 2136-2139 [Abstract] ( 96 ) HTML (1 KB)  PDF (1298 KB)  ( 117 ) 2140 Comparison of curative effect of hypertensive cerebral hemorrhage patients of different drainage treatment of large basal ganglia HU Shi-jie, LV Chao, HU Xue-an,et al DOI: 10.3969/j.issn.1671-7171.2016.11.020 【Objective】To compare the clinical efficacy of ultra-early minimally invasive puncture drainage, posterior frontal approach for aspiration and drainage of basal ganglian hematomas and small bone window CT guided drilling drainage on patients with hypertensive cerebral hemorrhage in basal ganglia.【Methods】Ninety cases of hypertensive cerebral hemorrhage in our hospital from January 2015 to January 2016 were chosen, all objects were divided into three groups according to the random grouping principle: the group of ultra-early minimally invasive puncture drainage(Group A), the group of posterior frontal approach for aspiration and drainage of basal ganglian hematomas (Group B) and the group of small bone window CT guided drilling drainage (Group C), 30 cases for each. Postoperative hematoma absorption, neurological impairment score (NIHSS score), ability of daily life score (ADL score) and postoperative complications of the three groups of patients were analyzed and compared.【Results】The hematoma size of the Group A was significantly smaller than that of the Group B and the Group C, the difference was statistically significant (P<0.05); The total absorption time of hematoma in the Group A was significantly shorter than that in the Group B and the Group C, the difference was statistically significant (P<0.05); The NIHSS score of the Group A was significantly better than that of the Group B and the Group C, and the difference was statistically significant (P<0.05),and the ADL score was significantly better than that of the Group B and the Group C, the difference was statistically significant (P<0.05); The incidence of postoperative complications in the Group A was 3.33% (1/30), which was significantly lower than that in the Group B 30.0%(9/30) and the Group C 36.67%(11/30),the difference was statistically significant (P<0.05).【Conclusion】Ultra early minimally invasive surgery for cerebral hemorrhage in basal ganglia has obvious curative effect, rapid recovery and less adverse reactions, it is worth to be widely used in clinical practice. 2016 Vol. 33 (11): 2140-2142 [Abstract] ( 54 ) HTML (1 KB)  PDF (1264 KB)  ( 74 ) 2143 Levels of hs-CRP, TB, and D-D in Patients with Cerebrovascular Disease and Their Clinical Significance FU Ya-hong, WU Xiao-lin, MA Ran-ran DOI: 10.3969/j.issn.1671-7171.2016.11.021 【Objective】 To observe the levels of the high sensitive C-reactive protein (hs-CRP), bilirubin (TB), and two D- dimer levels in patients with cerebral vascular diseases and to explore their clinical significance. 【Methods】 A total of 92 patients with cerebral vascular disease treated in our hospital from March 2014 to June 2015 were selected as our study population; the 92 patients were split into two groups. One group had 52 cases of cerebral hemorrhage, and another had 40 cases of cerebral infarction. Forty healthy adults, who were in the hospital at the same time, were selected as the control group. The differences in hs-CRP, TB, D-D, and related inflammatory cytokines were observed in the three groups. Differences between the different clinical characteristics were also monitored.【Results】The levels of hs-CRP and D-D in the patients with cerebral infarctions and cerebral hemorrhages were higher than those in the control group while the TB levels was lower than that in the control group (P<0.05). There was no significant difference in any of the three measurements between the cerebral infarction group and the cerebral hemorrhage group. IL-6, IL-10, and TNF- alpha levels of inflammatory cytokines were higher in the cerebral infarction and hemorrhage groups than in the control group (P<0.05); there were no significant differences between the two groups themselves, however. 【Conclusion】Patients with cerebral vascular diseases have higher hs-CRP and DD levels, but lower TB levels than normal patients. 2016 Vol. 33 (11): 2143-2145 [Abstract] ( 52 ) HTML (1 KB)  PDF (1270 KB)  ( 58 ) 2147 Effects of 0.125% Levobupivacaine with Different Concentrations of Sufentanil on Patient-Controlled Epidural Analgesia (PCEA) After Cesarean Section LI Wen- yan DOI: 10.3969/j.issn.1671-7171.2016.11.022 【Objective】To observe the clinical effects of 0.125% Levobupivacaine with different concentrations of sufentanil on patient-controlled epidural analgesia (PCEA) after cesarean section, and to determine the suitable concentration of sufentanil for this process. 【Methods】One hundred twenty (n=120) cases of full-term, single-fetal women who elected for cesarean section in our hospital were selected as the study subjects. The women aged 23 ~ 34 years old, weighed 58 ~ 80 kg, and had ASA class of Ⅰ or Ⅱ. According to a random number table, the 120 women were evenly divided into 3 groups (n=40 cases). Groups Ⅰ, Ⅱ, and Ⅲ, respectively, were given 0.4, 0.6, and 0.8 μg/mL of sufentanil combined with 0.125% Levobupivacaine. The loading dose was 5 mL, continuous infusion dose was 2 ml, the single drug dose was 2 ml, and the locking time was 15 min. The Visual Analogue Scale (VAS) was used to evaluate the patients' degree of pain 48 h postoperative. If the VAS score was ≥4, then the PCEA was deemed as a failure. A modified Bromage scoring system was used to evaluated the lower limb movement. Serum prolactin levels before anesthesia (T0), 24 h after surgery (T1), and 48 h after surgery (T2) were recorded along with the times of colostrum. The total number of PCEA uses, postoperative nausea, vomiting, lethargy, itching, low blood pressure, respiratory depression, bradycardia, urinary retention, and other adverse reactions were observed.【Results】The number of PCEA total uses, PCEA failure rate, and times of colostrum in groups Ⅱ and Ⅲ were lower than those in group Ⅰ. The serum prolactin levels of group Ⅱ and Ⅲ 24 h and 48 h after surgery were significantly higher than those of group Ⅰ, with a statistically significant difference (P<0.05). The number of PCEA uses, PCEA failure rate, times of colostrum, and the serum prolactin levels 24 h and 48 h after surgery were not significantly different between groups Ⅱ and Ⅲ (P>0.05). The modified Bromage scores and their changes in the three groups had no statistically significant differences (P>0.05). The incidence of postoperative adverse reaction of group Ⅲ was significantly higher than that of groups Ⅰ and Ⅱ the difference was statistically significant (P<0.05). The incidence of adverse reactions in groups Ⅰ and Ⅱ, however, had no statistically significant difference (P>0.05). 【Conclusion】It is determined that 0.6 ug/ml is the suitable concentration of sufentanil to use in conjunction with 0.125% levobupivacaine for PCEA after cesarean section. 2016 Vol. 33 (11): 2147-2150,2151 [Abstract] ( 51 ) HTML (1 KB)  PDF (1269 KB)  ( 31 ) 2149 Study on Airway Inflammation Phenotypes and Clinical Features in Asthmatic Patients LI Wen-bi DOI: 10.3969/j.issn.1671-7171.2016.11.023 【Objective】To analyze the airway inflammation phenotypes and clinical features of severe asthma compared to mild-moderate ("common") asthma. 【Methods】A total of 417 cases of asthma were retrospectively analyzed in our hospital from January 2012 to August 2015. Out of these, 43 patients were classified as the severe asthma group, and 374 patients as the common asthma group. All patients received induced sputum cell counts and pulmonary function tests, and all received fractional exhaled nitric oxide (FENO) tests. The airway inflammation phenotypes were defined and the clinical features of patients with severe asthma were studied. 【Results】①Age, BMI, weight, and induced sputum neutrophil of the two groups had no statistical significance (P>0.05). Differences in FEV1/FVC, induced sputum acidophilic granulocyte and FENO of the two groups were statistically significant (P<0.05). ② There were no differences between the severe asthma group and the common asthma group in the distributions (P>0.05). The distribution of airway inflammation phenotypes of asthma was as follows: eosinophilic subtype, mixed granulocytic subtype, neutrophilic subtype, and paucigranulocytic subtype. ③ FENO, FEV1/FVC(%) and FEV1 had significant statistical difference (P<0.05) in severe asthmatic patients with different airway inflammatory phenotypes, and the neutrophil type was the most severe type of severe asthma with lung function damage. 【Conclusion】Eosinophilic subtype is the most common airway inflammatory phenotypes of asthma. Neutrophilic subtype may be the most intractable subtype with severely damaged pulmonary function in severe asthma. 2016 Vol. 33 (11): 2149-2151 [Abstract] ( 74 ) HTML (1 KB)  PDF (1278 KB)  ( 68 ) 2152 Effect of Femtosecond Laser Assistance in Cataract Ultrasonic Emulsification Operation ZHENG Bo DOI: 10.3969/j.issn.1671-7171.2016.11.024 【Objective】To investigate the effect of femtosecond laser in cataract ultrasonic emulsification operation. 【Methods】Two hundred and eighty-two cases (297 eyes) of patients underwent cataract ultrasonic emulsification operation in our hospital from January 2014 to December 2015 were divided according to the different operation mode into femtosecond laser assisted group (the observation group,157 cases with 161 eyes) and the traditional ultrasonic phacoemulsification group (125 cases of 136 eyes).The observation group was treated with ultrasonic phacoemulsification assisted with femtosecond laser , while the control group with traditional ultrasonic phacoemulsification therapy .The process of the operation of the average ultrasonic energy(AVE), the effective phaco time(EPT), the surgical induced astigmatism 2 months postoperation(SIA), the best corrected visual acuity(BCVA), corneal endothelial cells lost rate and complications were observed and recorded. 【Results】 The average ultrasonic energy (AVE) in the process of operation of the femtosecond laser group was 6.5± 2.1% ,which was significantly less than that of the conventional phacoemulsification group 10.0±1.5%, the EPT was (6.1±2)s , which was significantly shorter than that of the control group (8.2 ±1.5)s, the difference was statistically significant (P<0.01). In the observation group, the SIA two months after operation was significantly less than that of the control group, the difference was statistically significant(P<0.05). There was no significant difference in BCVA between the two groups (P>0.05); The corneal endothelial cell loss rate in the observation group was (8.4 ±4.3)%, which was significantly lower than that of the control group (15.9 ±7.4)%, the difference was statistically significant (P<0.05); no serious complications occurred in the two groups.【Conclusion】 Femtosecond laser assistance is an effective and safe approach in cataract ultrasonic emulsification operation, which is able to reduce AVE and EPT significantly, minimize SIA and the loss rate of corneal endothelium. It is worthy of clinical popularization and application. 2016 Vol. 33 (11): 2152-2154 [Abstract] ( 49 ) HTML (1 KB)  PDF (1269 KB)  ( 48 ) 2155 Application of Sevoflurane and Remifentanil and its Effect on Inflammatory Cytokines in Obstetric General Anesthesia YE Yong-ke DOI: 10.3969/j.issn.1671-7171.2016.11.025 【Objective】To study the effects of sevoflurane combined with remifentanil in obstetric general anesthesia and its effect on inflammatory cytokines. 【Methods】 One hundred pregnant women in our obstetrics department were divided into two groups according to the chronology of their arrival: Group A and group B (n=50). Group B received propofol and remifentanil anesthesia while Group A received anesthesia with sevoflurane and remifentanil. The anesthetic effects and the impact of anesthesia on the inflammatory cytokines were observed. 【Results】 The change in mean arterial pressure (MAP) and heart rate (HR) in group A at different time points was not significantly different (P＞0.05). In group B, MAP and HR were significantly lower at the time of induction and time of delivery than before induction, 5 min after delivery, and after extubation (P<0.05). MAP and HR at the time of induction and time of delivery in group A was much higher than in group B. The levels of IL-6, IL-10, and TNF-α were significantly lower 5 min after delivery in group A than in group B (P<0.05). The breathing recovery time in group A was (10.3±1.7)min, the extubation time was (12.6±1.2) min, and the time it took to respond to the command "open your eyes" was (11.8±1.9) min. These values were lower than those of group B, which were (13.8±1.1, 18.3±2.3, 15.3±2.4) min, respectively. The differences were statistically significant (P<0.05). 【Conclusion】Sevoflurane combined with remifentanil is useful for general anesthesia in the obstetrics department. The release of inflammatory cytokines was relieved. The anesthesia stress response was less and it is worthy for clinical applications. 2016 Vol. 33 (11): 2155-2157,2159 [Abstract] ( 52 ) HTML (1 KB)  PDF (1247 KB)  ( 73 ) 2157 Clinical Significance of Bone Metabolism Biochemical Indexes Detection in High-risk Elderly Patients with Osteoporosis GU Yan DOI: 10.3969/j.issn.1671-7171.2016.11.026 【Objective】To investigate the clinical significance of bone metabolism biochemical indexes detection in high-risk elderly patients with osteoporosis (OP). 【Methods】Elderly patients with OP (group B,n=67), elderly patients with high-risk of OP (group A, n=75) and elderly patients without OP (control group, n=52) were selected as study subjects. Bone mineral density (BMD) of lumbar L2~4 and femoral neck was measured. Levels of bone metabolism indexes, including serum calcium (Ca), phosphorus (P), β-Crosslaps (β-CTX), N-terminal osteocalcin (N-MID), total collagen type I amino-terminal propeptide (PINP) and 25-hydroxy vitamin D [25-(OH) D3] were determined. 【Results】There were no significant differences in serum Ca and P between the three groups (P>0.05). P I NP and β-CTX in group B were higher than those in group A and the control group while N-MID and BMD of lumbar L2~4 and femoral neck were lower in group B than those in group A and the control group(P<0.05). There were no significant differences in other indexes (P>0.05). There was significant difference in PINP between group A and the control group (P<0.05). The 25-(OH) D3 in group B and group A were lower than that in control group (P<0.05), but there was no significant difference between group A and group B (P>0.05). 【Conclusion】Dynamic monitoring of changes of levels of PINP and 25-(OH) D3 can be used to screen elderly patients with high risk of OP. 2016 Vol. 33 (11): 2157-2159 [Abstract] ( 57 ) HTML (1 KB)  PDF (1272 KB)  ( 63 ) 2160 Clinical Efficacy of LCP Combined with MIPPO in the Treatment of Elderly Patients with Distal Tibial Fractures:30 Cases Report LIU Fan, BAO Xi-lang DOI: 10.3969/j.issn.1671-7171.2016.11.027 【Objective】To investigate the clinical value of locking compression plate (LCP) combined with Minimally Invasive Percutaneous Plate Osteosynthesis(MIPPO) in the treatment of elderly patients (>65) with distal tibial fractures. 【Methods】Sixty patients with distal tibial fractures were enrolled in this study and were randomly assigned to two groups: the observation group was treated with LCP combined with MIPPO while the control group was treated with the open fixation method. In the observation group, the suitable LCP was assigned according to the different fracture types and fracture lengths, and prebending was done according to the physiological radial degrees of each patient. After assigning the suitable LCP and completing prebending, an incision was made at the medial malleolus and plate osteosynthesis was performed; perspective alignment was fixed by screws. Patients in both groups were followed up for 24 months post-operation, and the curative effects were compared. 【Results】The intraoperative bleeding volume, operation time, and other corresponding indices were lower in the observation group than in the control group. The rate of improvement in ankle joint function was higher in the observation group than in the control group (P<0.05). The rate of post-operative complications were lower in the observation group than in the control group (P<0.05). 【Conclusion】LCP combined with MIPPO technology in the treatment of elderly patients with distal tibial fractures has a better effect and it is safer to use than the generic open fixation method-and is worthy of further clinical application. 2016 Vol. 33 (11): 2160-2162 [Abstract] ( 44 ) HTML (1 KB)  PDF (1673 KB)  ( 33 ) 2163 Application Value of Behavioral Nursing in the Rehabilitation of Elderly Patients with Cerebral Infarction LI Jing-yan DOI: 10.3969/j.issn.1671-7171.2016.11.028 【Objective】To explore the application value of behavioral nursing in the rehabilitation of elderly patients with acute cerebral infarction (ACI).【Methods】A total 105 cases of elderly patients with cerebral infarction treated in our hospital from June 2014 to October 2015 were randomly divided into a control group and an observation group. The control group was given routine nursing, while the observation group was given behavioral nursing on the basis of routine nursing care. After 4 weeks of intervention, the differences between the ability of daily life, motor function and quality of life between the two groups were compared.【Results】Before intervention, the BI (Barthel Index) scores and total scores of the two groups had no significant difference. After the intervention, the above indexes of the two groups all improved, and the total score of patients in the observation group was higher than that of the control group; the difference was statistically significant (P<0.05). Before the intervention, the FMA (Fugl-Meyer) scores of the two groups had no significant difference; after the intervention, the scores of the two groups were higher than before the intervention, and the score of the observation group increased more significantly (P<0.05). Before intervention, the quality of life score of the two groups had no significant difference; after the intervention, the index of the two groups all increased compared with that before the intervention, and the change in the observation group was more obvious than that in the control group (P<0.05). 【Conclusion】The application of behavioral nursing in the rehabilitation of elderly patients with cerebral infarction can significantly improve the exercise capacity and improve the quality of life of patients with cerebral infarction. 2016 Vol. 33 (11): 2163-2165 [Abstract] ( 64 ) HTML (1 KB)  PDF (1267 KB)  ( 84 )

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