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Analysis of the Anesthesia Effect of Seven Sevoflurane in the Operation of Children with low Body Mass |
QIU Zheng-guo, HAN Li-feng, CHEN Bo |
Department of Anesthesiology,XD Group Hospital,Xi'an 710077,Shaanxi |
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Abstract 【Objective】To investigate the anesthetic effect of seven sevoflurane in children with low body mass. 【Methods】A total of 92 cases of low-weight children who were undergoing abdominal surgery were divided using a random number table into a sevoflurane group and a ketamine group, with 46 cases in each group. In the sevoflurane group, 3% sevoflurane was used for inhalation anesthesia for the abdominal surgery. The inhalation concentration increased by 1% for each three breaths, with a maximum control of 5%. In the ketamine group, patients received 5mg / kg ketamine through intravenous anesthesia. The efficacy and safety of the two methods of anesthesia were compared. 【Results】The time of disappearance of eyelash reflex, pain disappearance time, recovery time and postoperative VAS scores were significantly lower in the sevoflurane group than in the ketamine group; the differences were statistically significant (P<0.05). The fluctuations in MAP, heart rate (HR) and oxygen saturation (SpO2) during surgery and post-operation were more obvious than in the ketamine group than in the sevoflurane group; the differences were statistically significant (P<0.05). The rate of adverse reactions in the sevoflurane group was 6.52%, significantly lower than the rate of 21.74% in the ketamine group (P<0.05). 【Conclusion】 Seven sevoflurane in children with low body mass has the advantages of quick onset of anesthesia, little effect on hemodynamics and low incidence of adverse reactions after operation.
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Received: 08 June 2016
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[1] 熊虹飞, 刘鸿涛, 田妍静,等.七氟烷不同吸入深度在小儿全麻诱导中的应用[J].山西医科大学学报, 2015, 46(4):375-378. [2] 田鹏声, 张全意, 张朝宾,等. 比较七氟烷吸入复合应用喉罩与氯胺酮基础麻醉在麻醉诱导中的有效性和安全性[J].中国循环杂志, 2014,29(7):537-539. [3] Liang P,Zhou C,Li KY,et al. Effect of flumazenil on sevoflurane requirements for minimum alveolar anesthetic concentrationawake and recovery status[J].Int J Clin Exp Med,2014, 7(3):673-679. [4] 张晓芳, 张丽香. 低出生体质量儿相关危险因素及预后分析[J].中国药物与临床, 2014,14(11):1565-1567. [5] 倪玮峰, 杨海宁, 施岳柱,等. 芬太尼复合七氟烷在小儿短小手术麻醉中的效果评价[J].海军医学杂志, 2014,35(5):411-412. [6] 曹译匀, 陈瑾, 李红萍,等. 七氟烷吸入联合瑞芬太尼静脉麻醉用于小儿气管异物取出术的效果观察[J].宁夏医科大学学报, 2013, 35(7):798-800. [7] Negargar S, Peirovifar A, Mahmoodpoor A,et al.Hemodynamic parameters of lowflow isoflurane and lowflow sevoflurane anesthesia during controlled ventilation with laryngeal mask airway[J].Anesthesiol Pain Med,2014, 4(5):15. [8] Zarmina Ehsan MD, Mohamed Mahmoud MD, Shott SR,et al.The effects of anesthesia and opioids on the upper airway: A systematic review[J].Laryngoscope,2016, 126(1):270-284. |
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