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Quick Search     Adv Search 2026 Vol. 43, No. 8 Published: 2026-08-26   1233 Effect of Phased Rehabilitation Training in Patients Undergoing Arthroscopic LARS Artificial Ligament Reconstruction YANG Nan, YU Jiangfei, LI Li, SONG Ying, JIN Yigao, ZHU Peili, DONG Yijun DOI: 10.3969/j.issn.1671-7171.2026.08.001 【Objective】 To evaluate the effectiveness of a phased rehabilitation program in patients undergoing arthroscopic LARS artificial ligament reconstruction. 【Methods】 A total of 78 patients who underwent arthroscopic anterior cruciate ligament (ACL) reconstruction with LARS artificial ligament at Nanyang Hospital of Traditional Chinese Medicine from January 2023 to September 2025 were enrolled and randomly divided into an observation group and a control group, each consisting of 39 patients. The control group received standard postoperative care, routine rehabilitation exercises, and health education, while the observation group received a phased rehabilitation program in addition to the same interventions as the control group. Postoperative visual analog scale (VAS) scores, Lysholm knee function score (Lysholm score), manual muscle testing (MMT) grades, knee circumference, swelling resolution time, and adverse events were compared between the two groups immediately after surgery and at 3 months postoperatively. 【Results】 At 3 months post-surgery, both groups showed decreased VAS scores and improved Lysholm scores; however, the observation group had significantly lower VAS scores and higher Lysholm scores than the control group (all P<0.05). Compared to immediately after surgery, MMT grades in both groups got improved, and the observation group demonstrated better MMT grades than the control group (all P<0.05). At 3 months post-surgery, the observation group had smaller knee circumference and shorter swelling resolution time than the control group (all P<0.05). The overall incidence of adverse reactions in the observation group was lower than that in the control group (P<0.05). 【Conclusion】 In patients undergoing arthroscopic LARS artificial ligament reconstruction, a phased rehabilitation program can significantly reduce pain, promote recovery of knee function and muscle strength, decrease knee circumference, shorten swelling resolution time, and is associated with high safety. 2026 Vol. 43 (8): 1233-1236 [Abstract] ( 6 ) HTML (1 KB)  PDF (1177 KB)  ( 1 ) 1237 Effects of Perioperative Team-Based Interpersonal Psychological Support Intervention on Psychological Status and Coping Styles in Patients Undergoing Vitrectomy LI Yanfei, MA Yanling, ZHANG Yuxin, LI Xiang DOI: 10.3969/j.issn.1671-7171.2026.08.002 【Objective】 To explore the effects of perioperative team-based interpersonal psychological support intervention on psychological status and coping styles in patients undergoing vitrectomy. 【Methods】 This was a prospective randomized controlled trial. A total of 90 patients receiving vitrectomy in Henan Provincial People's Hospital from January 2023 to November 2025 were enrolled and divided into the control group and the observation group by random number table method, with 45 cases in each group. The control group received routine perioperative psychological intervention, while the observation group received perioperative team-based interpersonal psychological support intervention. Psychological status and coping styles of the two groups were compared on the day of admission and one week after discharge. 【Results】 At one week after discharge, the anxiety score, depression score and total score of both groups were lower than those on admission (all P<0.05); moreover, the anxiety score, depression score and total score in the observation group were lower than those in the control group (all P<0.05). At one week after discharge, the positive confrontation score of both groups increased compared with admission (all P<0.05), whereas resignation and avoidance scores decreased (all P<0.05). The observation group obtained higher positive confrontation score (P<0.05) and lower resignation and avoidance scores than the control group(all P<0.05). 【Conclusion】 Perioperative team-based interpersonal psychological support intervention can effectively improve psychological status and enhance coping capacity in patients undergoing vitrectomy. 2026 Vol. 43 (8): 1237-1240 [Abstract] ( 4 ) HTML (1 KB)  PDF (1177 KB)  ( 1 ) 1241 Effectiveness of a Remote Management Model Based on Electronic Stethoscopes in Preschool Children with Recurrent Wheezing in Remote Areas ZHANG Yanhan, LI Jinying, LI Julong, ZHANG Jing, FU Peihua, LIN Feng, LI Shuangqiang, LI Hengzhi, ZHANG Qiaozhen, WANG Juan DOI: 10.3969/j.issn.1671-7171.2026.08.003 【Objective】 To evaluate the effectiveness of a remote management model based on electronic stethoscopes in preschool children with recurrent wheezing in remote areas. 【Methods】 A total of 66 preschool children with recurrent wheezing who visited People's Hospital of Gongshan County, Nujiang Prefecture of Yunnan between February 2024 and February 2025 were selected as study subjects and randomly divided into a control group and an observation group, each comprising 33 cases. The control group received routine follow-up and standard management measures, while the observation group received the same interventions plus a remote management model based on electronic stethoscopes. Over a 12-month follow-up period, we compared the number of wheezing episodes, respiratory infections, days of systemic corticosteroid use, hospitalizations, outpatient and emergency visits due to wheezing, average monthly medical costs, and average monthly total healthcare-related expenses between the two groups. Additionally, we assessed the Children's Respiratory and Asthma Control Test (TRACK) scores and the Pediatric Quality of Life Inventory (PedsQLTM4.0) scores. 【Results】 At the end of follow-up, the observation group showed significantly fewer wheezing episodes, respiratory infections, outpatient/emergency visits, and hospitalizations than the control group (all P<0.05). The observation group also had significantly shorter duration of systemic corticosteroid use and lower average monthly medical and total healthcare-related costs compared to the control group (all P<0.05). Furthermore, TRACK and PedsQLTM4.0 scores in the observation group were significantly higher than those in the control group (all P<0.05). 【Conclusion】 The remote management model based on electronic stethoscopes enables continuous monitoring and standardized care for preschool children with recurrent wheezing in remote areas, effectively reducing wheezing episodes and healthcare resource utilization, improving disease control, and enhancing quality of life, thus demonstrating significant clinical value. 2026 Vol. 43 (8): 1241-1244 [Abstract] ( 7 ) HTML (1 KB)  PDF (1180 KB)  ( 2 ) 1245 Levels of Peripheral Blood Treg Cells and NF-κB-p65 in Patients with Parkinson's Disease and their Clinical Significance Wang Yachan, Chen Yufei, Wang Qiuju DOI: 10.3969/j.issn.1671-7171.2026.08.004 【Objective】 To investigate the levels of peripheral blood Treg cells and nuclear factor-κB p65 (NF-κB-p65) and their clinical significance in patients with Parkinson's disease (PD). 【Methods】 A total of 82 PD patients admitted to the Ninth People's Hospital of Zhengzhou from April 2019 to July 2022 were enrolled and divided into good-prognosis group (n=57) and poor-prognosis group (n=25) according to their prognosis. Flow cytometry was used to detect the level of Treg cells, and reverse transcription-polymerase chain reaction (RT-PCR) was applied to detect NF-κB-p65 level. The prognostic influencing factors of PD patients were analyzed, and the predictive value of Treg cells and NF-κB-p65 for poor prognosis in PD patients was evaluated. 【Results】 The levels of hypoxia-inducible factor-1α (HIF-1α), interleukin-1β (IL-1β) and NF-κB-p65 in the poor-prognosis group were higher, while Treg cell level was lower than those in the good-prognosis group (all P<0.05). Binary Logistic regression analysis showed that HIF-1α, IL-1β and NF-κB-p65 were risk factors for poor prognosis in PD patients (all P<0.05), whereas Treg cell was a protective factor (P<0.05). Pearson correlation analysis demonstrated that poor prognosis of PD patients was positively correlated with HIF-1α, IL-1β and NF-κB-p65 (r=0.529, 0.537, 0.602, all P<0.05), and negatively correlated with Treg cells (r=-0.504, P<0.05). Receiver operating characteristic curve analysis indicated that the combined detection of HIF-1α, IL-1β, NF-κB-p65 and Treg cells possessed high predictive value for poor prognosis of PD patients (area under the curve＞0.9). 【Conclusion】 Low expression of peripheral blood Treg cells and over-expression of inflammatory factor NF-κB-p65 before treatment may suggest poor post-treatment prognosis in PD patients, which can serve as indicators for poor prognosis of PD patients. 2026 Vol. 43 (8): 1245-1248 [Abstract] ( 5 ) HTML (1 KB)  PDF (1242 KB)  ( 1 ) 1249 Efficacy and Safety of Ticagrelor Combined with Atorvastatin in Patients with Coronary Heart Disease Complicated with Hyperlipidemia ZHU Xiaoli, ZHU Suzhen, LI Danli, WANG Bo, YANG Enbo DOI: 10.3969/j.issn.1671-7171.2026.08.005 【Objective】 To investigate the efficacy and safety of ticagrelor combined with atorvastatin in patients with coronary heart disease (CHD) complicated with hyperlipidemia. 【Methods】 A total of 104 patients with CHD complicated with hyperlipidemia treated at Sanguanmiao Zhengshang Road Community Health Service Center, the Second Affiliated Hospital of Zhengzhou University from January 2023 to March 2025 were enrolled and divided into the control group (atorvastatin treatment) and the observation group (ticagrelor combined with atorvastatin treatment) by random number table method, with 52 cases in each group. Clinical efficacy, blood-lipid levels [high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), triglyceride (TG), total cholesterol (TC)], cardiac function indicators [cardiac output, left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVDD)], laboratory indicators [vascular endothelial growth factor (VEGF), high-sensitivity C-reactive protein (hs-CRP), homocysteine (Hcy)] and incidence of adverse reactions were compared between the two groups. 【Results】 After 6-month follow-up, the total clinical effective rate of the observation group was 92.31% (48/52), which was higher than 76.92% (40/52) of the control group (χ2=4.727, P<0.05). After treatment, serum levels of LDL-C, TG and TC decreased, while serum HDL-C level increased in both groups (all P<0.05). There were no significant inter-group differences in HDL-C, LDL-C, TG and TC after treatment (all P>0.05). After treatment, cardiac output and LVEF increased, whereas LVDD decreased in both groups; the observation group had higher cardiac output and LVEF and lower LVDD compared with the control group (all P<0.05). After treatment, serum VEGF level increased, while hs-CRP and Hcy levels decreased in both groups. The observation group presented higher VEGF level and lower hs-CRP and Hcy levels than the control group (all P<0.05). The incidence of adverse reactions was 9.62% (5/52) in the observation group and 11.54% (6/52) in the control group, without statistically significant difference (χ2=0.102, P>0.05). 【Conclusion】 Ticagrelor combined with atorvastatin achieves favorable efficacy for patients with coronary heart disease complicated with hyperlipidemia. It can effectively improve cardiac function and enhance vascular repair capacity with good safety profile. 2026 Vol. 43 (8): 1249-1252 [Abstract] ( 6 ) HTML (1 KB)  PDF (1185 KB)  ( 1 ) 1253 Efficacy of Lacosamide Tablets Combined with Levetiracetam Tablets in the Treatment of Drug-Resistant Focal Epilepsy SUI Ruibin, GUO Cancan, XUE Hongfei, GAO Lan, YANG Yahong, FAN Jinlin, GUO Dayun DOI: 10.3969/j.issn.1671-7171.2026.08.006 【Objective】 To investigate the efficacy of lacosamide tablets combined with levetiracetam tablets in the treatment of drug-resistant focal epilepsy (DRE) and the impact on patients' cognitive function. 【Methods】 A total of 80 patients with DRE admitted to Zhengzhou Central Hospital Affiliated to Zhengzhou University from January 2022 to December 2024 were randomly divided into an observation group and a control group, with 40 patients in each group. Patients in both groups continued to take their original antiepileptic drug regimens. The control group was additionally treated with levetiracetam tablets, while patients in the observation group received lacosamide tablets combined with levetiracetam tablets. Both groups were treated continuously for 6 months. Clinical efficacy, seizure frequency before and after treatment, cognitive function [assessed by the Mini-Mental State Examination (MMSE) score and Montreal Cognitive Assessment (MoCA) score], and serum levels of S-100β protein and neuron-specific enolase (NSE) were compared between the two groups. 【Results】 The total clinical response rate in the observation group (95.00%) was higher than that in the control group (75.00%) (P<0.05). After treatment, seizure frequency and serum levels of S-100β and NSE decreased(all P<0.05), while MMSE and MoCA scores increased in both groups compared with those before treatment (all P<0.05). Moreover, the improvements in the above indicators were more significant in the observation group than in the control group (all P<0.05). 【Conclusion】 Lacosamide tablets combined with levetiracetam tablets can effectively improve clinical efficacy, reduce seizure frequency, improve cognitive function, and decrease serum S-100β and NSE levels in patients with DRE. The therapeutic efficacy of the combined therapy is superior to that of levetiracetam monotherapy. 2026 Vol. 43 (8): 1253-1255 [Abstract] ( 6 ) HTML (1 KB)  PDF (1161 KB)  ( 1 ) 1256 Efficacy of Atorvastatin Combined with Mechanical Thrombectomy in Patients with Acute Ischemic Stroke with Large Vessel Occlusion ZHOU Fugao DOI: 10.3969/j.issn.1671-7171.2026.08.007 【Objective】 To investigate the efficacy of atorvastatin combined with mechanical thrombectomy in patients with acute ischemic stroke with large-vessel occlusion (AIS-LVO). 【Methods】 The clinical data of 102 patients with AIS-LVO admitted to Luoyang Xinlicheng Hospital from January 2022 to December 2024 were retrospectively analyzed. Patients were divided into the control group (mechanical thrombectomy) and the observation group (atorvastatin combined with mechanical thrombectomy) according to treatment regimens, with 51 cases in each group. Clinical efficacy, incidence of vascular restenosis, blood lipid indicators [total cholesterol (TC), triglyceride (TG)], inflammatory factors [interleukin-8 (IL-8), high-sensitivity C-reactive protein (hs-CRP), tumor necrosis factor α (TNF-α)], neurological function [modified Rankin Scale (mRS) score], prognosis and incidence of adverse reactions were compared between the two groups. 【Results】 The total effective rate of the observation group was higher than that of the control group (P<0.05). The incidence of vascular restenosis in the observation group was lower than that in the control group (P<0.05). After treatment, serum levels of TC, TG, IL-8, hs-CRP and TNF-α decreased in both groups, and were lower in the observation group (all P<0.05). At 8-week follow-up after treatment, the observation group obtained lower mRS score and better prognosis compared with the control group (all P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups (P>0.05). 【Conclusion】 Atorvastatin combined with mechanical thrombectomy yields favorable efficacy for AIS-LVO. It can reduce the incidence of vascular restenosis, improve blood lipid profiles, decrease inflammatory factor levels, ameliorate neurological function and prognosis, with satisfactory safety. 2026 Vol. 43 (8): 1256-1259 [Abstract] ( 5 ) HTML (1 KB)  PDF (1189 KB)  ( 1 ) 1260 Effects of Adipose-Derived Stem Cell Conditioned Medium on Proliferation and Apoptosis of Human Frozen Shoulder Joint Capsular Fibroblasts and its Related Mechanism HUANG Xinji, LUO Shengcheng, ZHANG Cheng, WENG Xiaojun DOI: 10.3969/j.issn.1671-7171.2026.08.008 【Objective】 To investigate the effects of adipose-derived stem cell conditioned medium (ADSC-CM) on the proliferation and apoptosis of human frozen shoulder capsular fibroblasts and its underlying mechanism. 【Methods】 ADSC-CM was prepared in vitro. Primary human frozen shoulder capsular fibroblasts were cultured and identified. According to different cell interventions, cells were divided into control group (group A1), agonist group (group B1), ADSC-CM group (group C1), and ADSC-CM plus agonist group (group D1). After intervention, fibroblast proliferation and apoptosis, reactive oxygen species (ROS) level, and the expression levels of fibrosis-related proteins in transforming growth factor-β1/Smad (TGF-β1/Smad) signaling pathway were detected in each group. 【Results】 Compared with group A1, group C1 exhibited decreased fibroblast proliferation, increased apoptosis, reduced ROS content, and significantly down-regulated protein expression of collagen Ⅰ/Ⅲ, TGF-β1 and phosphorylated Smad2 (p-Smad2) (P<0.05). Group D1 showed similar inhibitory effects to group B1 (P<0.05), and the agonist could partially reverse the regulatory effect of ADSC-CM. 【Conclusion】 By down-regulating the expression of fibrosis-related proteins in the TGF-β1/Smad pathway, ADSC-CM inhibits fibroblast proliferation, induces fibroblast apoptosis and reduces intracellular ROS level, thereby exerting anti-fibrotic effects. It can provide experimental evidence for the treatment of patients with frozen shoulder. 2026 Vol. 43 (8): 1260-1264 [Abstract] ( 6 ) HTML (1 KB)  PDF (1507 KB)  ( 1 ) 1265 Efficacy of Kuntai Capsule Adjuvant to Hormone Replacement Therapy in the Treatment of Premature Ovarian Failure FAN Lili DOI: 10.3969/j.issn.1671-7171.2026.08.009 【Objective】 To investigate the efficacy of Kuntai capsule as adjuvant therapy to hormone replacement therapy for premature ovarian failure. 【Methods】 A total of 100 patients with premature ovarian failure treated in the 83rd Group Army Hospital of the Chinese People's Liberation Army from January 2024 to December 2025 were enrolled and divided into control group (hormone replacement therapy) and observation group (Kuntai capsule combined with hormone replacement therapy) according to different treatment regimens, with 50 cases in each group. Hormone levels including estradiol (E2), follicle-stimulating hormone (FSH) and luteinizing hormone (LH), modified Kupperman index score, endometrial thickness, ovarian ultrasound indicators [mean ovarian diameter (MOD), antral follicle count (AFC), peak systolic velocity (PSV) of ovarian artery, resistance index (RI) and pulsatility index (PI)], and incidence of adverse reactions were compared between the two groups. 【Results】 After treatment, the level of E2 in the observation group was higher than that in the control group (P<0.05), while the levels of FSH and LH were lower than those in the control group (all P<0.05). After treatment, the modified Kupperman index score of the observation group was lower and endometrial thickness was thicker compared with the control group (all P<0.05). MOD, AFC and ovarian artery PSV in the observation group were higher (all P<0.05), whereas ovarian artery RI and PI were lower (all P<0.05). There was no statistically significant difference in the total incidence of adverse reactions between the two groups (P>0.05). 【Conclusion】 Adjuvant treatment with Kuntai capsule combined with hormone replacement therapy can promote the recovery of hormone levels and improve ovarian function in patients with premature ovarian failure, with favorable safety profile. 2026 Vol. 43 (8): 1265-1267 [Abstract] ( 6 ) HTML (1 KB)  PDF (1163 KB)  ( 1 ) 1268 Predictive Value of Serum Prealbumin, Serum Amyloid A and Soluble Triggering Receptor Expressed on Myeloid Cells-1 for Prognosis in Patients with Severe Acute Pancreatitis ZHANG Wenyu, CAI Lingle, ZHANG Chen, ZHAO Guanlei DOI: 10.3969/j.issn.1671-7171.2026.08.010 【Objective】 To investigate the predictive efficacy of serum prealbumin (PA), serum amyloid A (SAA) and soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) for the prognosis of patients with severe acute pancreatitis (SAP). 【Methods】 A total of 121 patients with SAP admitted to our hospital from January 2023 to December 2025 were enrolled. Serum levels of PA, SAA and sTREM-1 were detected after admission. Prognosis was evaluated based on 28-day mortality after admission: 32 deceased patients classified as poor prognosis (the death group) and 89 surviving patients classified as good prognosis (the survival group). Clinical data were compared between the two groups, and prognostic influencing factors were analyzed. Receiver operating characteristic (ROC) curve was adopted to analyze the predictive value of related indicators for patient prognosis. 【Results】 The serum PA level in the poor prognosis group was significantly lower than that in the good prognosis group, while the levels of SAA and sTREM-1 in the poor prognosis group were markedly higher than those in the good prognosis group (P<0.05). The APACHE Ⅱ score and the proportion of complicated with multiple organ failure in the poor prognosis group were higher, whereas the proportion of mechanical ventilation was lower compared to the good prognosis group (P<0.05). Multivariate stepwise Logistic regression analysis revealed that PA was an independent protective factor for prognosis, while SAA, sTREM-1, APACHE Ⅱ score and multiple organ failure were independent risk factors (P<0.05). ROC curve analysis demonstrated that the combined detection of PA, SAA and sTREM-1 yielded a sensitivity of 90.60%, specificity of 91.00% and area under the curve of 0.934 for predicting patient prognosis, which were superior to the predictive performance of each single indicator (P<0.05). 【Conclusion】 Serum PA is an independent protective factor for the prognosis of SAP patients, and SAA and sTREM-1 are independent risk factors. Combined detection of the three biomarkers can effectively predict the prognostic outcomes of SAP patients. 2026 Vol. 43 (8): 1268-1271 [Abstract] ( 5 ) HTML (1 KB)  PDF (1244 KB)  ( 1 ) 1272 Effects of Enteral Nutrition Combined with Parenteral Nutrition Support on Immune Function and Nutritional Indicators in Patients Undergoing Radical Gastrectomy for Gastric Cancer WU Wenxue, QI Yan, TAO Guoqiang, WANG Wei, WANG Yue DOI: 10.3969/j.issn.1671-7171.2026.08.011 【Objective】 To investigate the effects of enteral nutrition (EN) combined with parenteral nutrition (PN) support on immune function and nutritional indicators in patients undergoing radical gastrectomy for gastric cancer. 【Methods】 A total of 80 patients who underwent radical gastrectomy for gastric cancer in Shanghai Pudong New District Punan Hospital from January 2023 to August 2025 were selected and divided into observation group and control group by random number table method, with 40 cases in each group. All patients received radical gastrectomy for gastric cancer. After surgery, the control group was given PN support, while the observation group received EN combined with PN support. Post-operative gastrointestinal function recovery time, defecation time, length of hospital stay and postoperative complications were compared between the two groups. The levels of albumin, prealbumin, hemoglobin, fasting blood glucose, insulin, immunoglobulin A (IgA), immunoglobulin G (IgG) and immunoglobulin M (IgM) were compared before and after operation. 【Results】 The gastrointestinal function recovery time, defecation time and length of hospital stay in the observation group were significantly shorter than those in the control group (all P<0.05). On postoperative day 7, there were no statistically significant differences in albumin, prealbumin, hemoglobin, fasting blood glucose and insulin in the observation group compared with preoperative levels (all P>0.05). In the control group, albumin, prealbumin and hemoglobin were significantly lower than preoperative values (all P<0.05), while fasting blood glucose and insulin were significantly higher than preoperative values (all P<0.05). The observation group had significantly higher albumin, prealbumin and hemoglobin (all P<0.05), and significantly lower fasting blood glucose and insulin (all P<0.05) compared with the control group. On postoperative day 7, IgA, IgG and IgM levels in both groups were significantly higher than preoperative levels, and those in the observation group were higher than in the control group (all P<0.05). The total incidence of postoperative complications was 22.50% (9/40) in the observation group and 27.50% (11/40) in the control group, with no statistically significant difference (χ2=0.267, P>0.05). 【Conclusion】 EN combined with PN support can improve postoperative immune function and nutritional status in patients with gastric cancer after radical gastrectomy, without increasing the incidence of postoperative complications. 2026 Vol. 43 (8): 1272-1275 [Abstract] ( 6 ) HTML (1 KB)  PDF (1183 KB)  ( 1 ) 1276 Predictive Value of Epicardial Adipose Tissue Thickness for Chronic Heart Failure in Patients with Type 2 Diabetes Mellitus YANG Zhenyu DOI: 10.3969/j.issn.1671-7171.2026.08.012 【Objective】 To investigate the predictive value of epicardial adipose tissue (EAT) thickness for chronic heart failure (CHF) in patients with type 2 diabetes mellitus (T2DM). 【Methods】 The clinical data of 120 patients with T2DM admitted to Anyang People's Hospital from May 2022 to May 2024 were retrospectively analyzed. Among them, 52 patients who developed CHF during follow-up were assigned to the observation group, and 68 patients without CHF were assigned to the control group. Glucose metabolic indicators [fasting plasma glucose (FPG), 2-hour postprandial plasma glucose (2hPG), glycated hemoglobin (HbA1c), fasting insulin (FINS)], EAT thickness and coronary artery disease burden (Gensini score) were compared between the two groups. Logistic regression was used to analyze the influencing factors for CHF in T2DM patients, and receiver operating characteristic (ROC) curve was adopted to evaluate the clinical predictive value of EAT thickness for CHF in T2DM patients. 【Results】 The levels of FPG, 2hPG and HbA1c in the observation group were higher, while FINS level was lower than those in the control group (all P<0.05). EAT thickness and Gensini score in the observation group were higher than those in the control group (all P<0.05). Logistic regression analysis demonstrated that FPG, FINS, EAT thickness and Gensini score were influencing factors for CHF in T2DM patients (all P<0.05). ROC curve analysis showed that the area under the curve of EAT thickness for predicting CHF in T2DM patients was 0.895 (95%CI:0.600-0.823), with a sensitivity of 88.76%, specificity of 88.24% and Youden index of 0.670. 【Conclusion】 EAT thickness presents favorable predictive value for CHF in T2DM patients and can be applied for clinical risk assessment. 2026 Vol. 43 (8): 1276-1278 [Abstract] ( 6 ) HTML (1 KB)  PDF (1211 KB)  ( 1 ) 1279 Value of MRI Combined with CTA or CT in Differentiating Vascular Parkinsonism from Idiopathic Parkinson's Disease BA Jiwei, WANG Huai, YANG Xiaohua, ZHANG Xiaojing DOI: 10.3969/j.issn.1671-7171.2026.08.013 【Objective】 To explore the differential value of magnetic resonance imaging (MRI) combined with computed tomography angiography (CTA) or CT for vascular Parkinsonism (VP) and idiopathic Parkinson's disease (PD). 【Methods】 The clinical data of 50 patients with VP (VP group) and 50 patients with PD (PD group) treated in Xuchang Wanrong Hospital of Traditional Chinese Medicine and Rehabilitation from May 2021 to May 2023 were retrospectively analyzed. All patients underwent MRI, CT or CTA examinations. The width of the midbrain-pontine sulcus, midbrain diameter, and the ratio of midbrain-pontine sulcus width to midbrain diameter were compared between the two groups. Lesions in the subcortical white matter, basal ganglia and thalamus were also compared. Receiver operating characteristic (ROC) curve was adopted to analyze the diagnostic performance of MRI combined with CT or CTA for identifying VP. 【Results】 The midbrain-pontine sulcus width and the ratio of midbrain-pontine sulcus width to midbrain diameter in the PD group were lower than those in the VP group, with statistically significant differences (all P<0.05). No significant difference was found in midbrain diameter between the two groups (P>0.05). The detection rates of lesions in subcortical white matter, basal ganglia and thalamus in the VP group were higher than those in the PD group, and the differences were statistically significant (all P<0.05). ROC curve analysis showed that the area under the curve (AUC) of MRI was 0.799 with a Youden index of 0.497; the AUC of CTA or CT was 0.834 with a Youden index of 0.615; the AUC of MRI combined with CTA or CT reached 0.951, which was significantly higher than that of MRI alone and CTA or CT alone (all P<0.05). 【Conclusion】 MRI combined with CTA or CT possesses high clinical value in the differential diagnosis of PD and VP, which is worthy of clinical promotion. 2026 Vol. 43 (8): 1279-1282 [Abstract] ( 7 ) HTML (1 KB)  PDF (1357 KB)  ( 1 ) 1283 Correlation between the Expression of Autophagy-Related Proteins in Fetal Membrane Tissues and Adverse Pregnancy Outcomes in Pregnant Women with Gestational Hypertension XIA Wenxiang, ZHENG Beibei, LIU Na DOI: 10.3969/j.issn.1671-7171.2026.08.014 【Objective】 To explore the correlation between the expression of autophagy-related proteins in fetal membrane tissues and adverse pregnancy outcomes in pregnant women with gestational hypertension. 【Methods】 A total of 86 pregnant women with gestational hypertension who received regular prenatal examinations in Dancheng County Maternal and Child Health Hospital from May 2020 to May 2023 were enrolled as the observation group and further divided into good-outcome subgroup and adverse-outcome subgroup according to pregnancy outcomes. Another 86 normal pregnant women receiving regular prenatal examinations during the same period were selected as the control group. Clinical data of all subjects were collected. Immunohistochemical staining was used to detect the expression of autophagy-related proteins Beclin-1, microtubule-associated protein 1 light chain 3-Ⅱ (LC3-Ⅱ) and sequestosome-1 (p62) in fetal membrane tissues. Risk factors for adverse pregnancy outcomes in patients with gestational hypertension were screened, and the predictive value of Beclin-1, LC3-Ⅱ and p62 expression in fetal membranes for adverse pregnancy outcomes was analyzed. 【Results】 The expression levels of Beclin-1 and LC3-Ⅱ in fetal membrane tissues of the observation group were higher than those of the control group (all P<0.05), while p62 level was lower (P<0.05). Among the 86 patients with gestational hypertension, 32 cases developed adverse pregnancy outcomes. The 24-hour urinary protein quantification, serum uric acid, vascular endothelial growth factor (VEGF), Beclin-1, LC3-Ⅱ, and the proportions of CD3+, CD56+, CD68+ positive cells in the adverse-outcome subgroup were higher than those in the good-outcome subgroup (all P<0.05), whereas p62 level was lower (P<0.05). 24-hour urinary protein quantification, serum uric acid, VEGF, Beclin-1, LC3-Ⅱ, p62, CD3+, CD56+ and CD68+ were influencing factors for adverse pregnancy outcomes in gestational hypertension (P<0.05). The area under the curve values of Beclin-1, LC3-Ⅱ, p62 and their combination for evaluating adverse pregnancy outcomes were 0.803, 0.792, 0.821 and 0.889, respectively. 【Conclusion】 Abnormal expression of Beclin-1, LC3-Ⅱ and p62 in fetal membrane tissues is correlated with adverse pregnancy outcomes in patients with gestational hypertension, which can assist in assessing the risk of adverse pregnancy outcomes. 2026 Vol. 43 (8): 1283-1286 [Abstract] ( 7 ) HTML (1 KB)  PDF (1247 KB)  ( 1 ) 1287 Clinical Study on the Combined Treatment of Anatomical Hemorrhoidectomy with Semi-Closed Suturing and Mucosal Ligation above Hemorrhoid for Mixed Hemorrhoids LU Wei, ZHU Guangyan, LI Ruihao DOI: 10.3969/j.issn.1671-7171.2026.08.015 【Objective】 To investigate the clinical efficacy of anatomical hemorrhoidectomy with semi closed suture combined with stapled mucosal ligation for the treatment of mixed hemorrhoids. 【Methods】 Clinical data of 86 patients with mixed hemorrhoids admitted to the Department of Surgery, Dayu Health Center of Jiyuan, from May 2023 to September 2024 were retrospectively analyzed. The patients were divided into an observation group and a control group according to the surgical method, with 43 cases in each group. The control group received conventional Milligan Morgan hemorrhoidectomy (external dissection and internal ligation), while the observation group was treated with anatomical hemorrhoidectomy with semi closed suture combined with stapled mucosal ligation. The two groups were compared in terms of stress response indicators [cortisol (Cor), adrenocorticotropic hormone (ACTH)], anorectal manometric parameters [anal resting rectal pressure (ARRP), anal maximum contractile pressure (AMCP), anal resting pressure (ARP)], postoperative complication rate, and pain intensity assessed by Visual Analogue Scale (VAS) at 6 h, 12 h, and 24 h postoperatively. 【Results】 At 1 day after surgery, serum Cor and ACTH levels in both groups were significantly higher than their preoperative levels (all P<0.05), however, there were no statistically significant differences between the two groups (all P>0.05). The VAS scores in the observation group at 6 h, 12 h, and 24 h postoperatively were all lower than those in the control group, with statistically significant differences (all P<0.05). At 1 month after surgery, ARRP, AMCP, and ARP in both groups were higher than the preoperative values, and the observation group showed significantly higher values than the control group (all P<0.05). The complication rate in the observation group was 9.30% (4/43), which was significantly lower than that in the control group [25.58% (11/43), χ2=3.957, P<0.05]. 【Conclusion】 Anatomical hemorrhoidectomy with semi closed suture combined with stapled mucosal ligation for treatment of mixed hemorrhoids can effectively alleviate stress responses, reduce postoperative pain, improve anorectal manometric function, and decrease the incidence of postoperative complications. 2026 Vol. 43 (8): 1287-1290 [Abstract] ( 5 ) HTML (1 KB)  PDF (1185 KB)  ( 1 ) 1291 Application Effect of an Intervention Model Based on the Broaden-and-Build Theory of Gratitude in Patients with Cervical Cancer ZHANG Wangli DOI: 10.3969/j.issn.1671-7171.2026.08.016 【Objective】 To explore the application effect of an intervention model based on the broaden-and-build theory of gratitude in patients with cervical cancer. 【Methods】 A total of 146 patients with cervical cancer admitted to First Affiliated Hospital of Henan University of Science and Technology from January 2022 to December 2023 were enrolled and randomly divided into an observation group and a control group using a random number table, with 73 patients in each group. The control group received routine nursing intervention, whereas the observation group received the intervention model based on the broaden-and-build theory of gratitude in addition to routine nursing. The two groups were compared before intervention and at 3 months after intervention in terms of nutritional status [hemoglobin (Hb), serum albumin (ALB), and prealbumin (PAB)], gratitude level [Gratitude Questionnaire-6 (GQ-6) score], self-care ability [Exercise of Self-Care Agency Scale (ESCA) score], fear of recurrence [Concerns About Recurrence Scale (CARS) score], and quality of life [European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) score]. 【Results】 After intervention, the levels of Hb, ALB, and PAB in the observation group were higher than those in the control group (all P<0.05). The GQ-6 score, ESCA score, and all dimensions of the EORTC QLQ-C30 in the observation group were higher than those in the control group, whereas the scores of all dimensions of CARS were lower than those in the control group (all P<0.05). 【Conclusion】 The intervention model based on the broaden-and-build theory of gratitude can significantly improve the nutritional status, psychological health, and quality of life of patients with cervical cancer, and enhance their self-care ability by alleviating their fear of cancer recurrence. 2026 Vol. 43 (8): 1291-1294 [Abstract] ( 6 ) HTML (1 KB)  PDF (1181 KB)  ( 1 ) 1295 Clinical Efficacy and Safety of Phloroglucinol Combined with Pantoprazole in the Treatment of Abdominal Pain Patients with Acute Gastroenteritis JIANG Peng DOI: 10.3969/j.issn.1671-7171.2026.08.017 【Objective】 To evaluate the clinical efficacy and safety of pantoprazole combined with phloroglucinol in the treatment of abdominal pain associated with acute gastroenteritis. 【Methods】 Clinical data of 104 patients with abdominal pain due to acute gastroenteritis treated at Henan Hongli Hospital from March 2023 to October 2024 were retrospectively analyzed. Patients were divided into a control group and an observation group according to the treatment received, with 52 cases in each group. The control group received pantoprazole alone, while the observation group received phloroglucinol in addition to pantoprazole. The clinical efficacy, serum levels of inflammatory cytokines [interleukin-6 (IL-6) and interleukin-8 (IL-8)], clinical indices, and adverse reactions were compared between the two groups.【Results】 After treatment, the overall response rate in the observation group was 98.08% (51/52), which was significantly higher than that in the control group [86.54%(45/52); χ2=4.875, P=0.027]. The time to relief of abdominal pain and the duration of medication use in the observation group were significantly shorter than those in the control group (both P<0.05). After treatment, serum IL-6 and IL-8 levels in the observation group were significantly lower than those in the control group (both P<0.05). The total incidence of adverse reactions in the observation group was 7.69% (4/52), compared with 13.46% (7/52) in the control group, but the difference was not statistically significant (χ2=0.915, P=0.339).【Conclusion】 Pantoprazole combined with phloroglucinol shows good clinical efficacy in treating abdominal pain due to acute gastroenteritis, as it suppresses inflammatory responses, shortens treatment duration, and exhibits a favorable safety profile. 2026 Vol. 43 (8): 1295-1297 [Abstract] ( 5 ) HTML (1 KB)  PDF (1158 KB)  ( 1 ) 1298 Correlation Analysis of Hepatitis B Serological Markers, Viral Load, and Liver Fibrosis Markers in Patients with Hepatitis B CHEN Yaohua, YUAN Linchao, LI Lin DOI: 10.3969/j.issn.1671-7171.2026.08.018 【Objective】 To investigate the correlation of liver fibrosis markers with hepatitis B serological markers (HBV five markers) and HBV-DNA viral load in patients with hepatitis B, and to evaluate their clinical significance. 【Methods】 A total of 137 patients with hepatitis B admitted between April 2024 and April 2025 were enrolled, including 113 patients with chronic hepatitis B (44 mild, 48 moderate, and 21 severe cases) and 24 patients with liver cirrhosis. HBV-DNA viral load and liver fibrosis markers, including procollagen type Ⅲ peptide (PCⅢ), type Ⅳ collagen (CⅣ), laminin (LN), and hyaluronic acid (HA), were compared among different patient groups. The levels of liver fibrosis markers were further analyzed according to HBV-DNA viral load. Spearman correlation analysis was performed to assess the correlations of HBV-DNA viral load, and liver fibrosis markers. 【Results】 The HBV-DNA viral load and the levels of PCⅢ, CⅣ, LN, and HA in patients with chronic hepatitis B were significantly lower than those in patients with liver cirrhosis (P<0.05). The levels of PCⅢ, CⅣ, LN, and HA were significantly correlated with HBV-DNA viral load in patients with hepatitis B (P<0.05). Patients in the HBeAg-positive chronic infection (high infectivity, named "Da Sanyang") group had significantly higher levels of PCⅢ, CⅣ, LN, and HA than the other hepatitis B groups (P<0.05). Correlation analysis showed that HBV-DNA viral load were positively correlated with liver fibrosis markers (P<0.05). 【Conclusion】 Hepatitis B serological markers and HBV-DNA viral load are closely associated with the degree of liver fibrosis in patients with hepatitis B. Active viral replication is strongly associated with the progression of liver fibrosis, particularly in patients with Da Sanyang. 2026 Vol. 43 (8): 1298-1301 [Abstract] ( 5 ) HTML (1 KB)  PDF (1182 KB)  ( 1 ) 1302 Application Effect of Mind Map Teaching Method Combined with Case Analysis Method in Ophthalmology Teaching ZHU Lijuan, WANG Yajuan, WANG Lili, DONG Shuqian DOI: 10.3969/j.issn.1671-7171.2026.08.019 【Objective】 To explore the application effect of mind map teaching combined with case analysis in ophthalmology teaching. 【Methods】 A total of 90 students receiving clinical internship in the First Affiliated Hospital of Zhengzhou University from November 2023 to November 2024 were selected and divided into a control group (receiving traditional teaching) and an observation group (receiving mind map teaching combined with case analysis) by random number table method, with 45 students in each group. The objective assessment scores, clinical risk identification ability, teaching outcomes, and students' teaching satisfaction were compared between the two groups. 【Results】 After teaching, students in the observation group obtained significantly higher scores in theoretical knowledge, skill operation and case analysis than those in the control group (all P<0.05). The scores of medical safety awareness and risk identification ability in the observation group were higher than those in the control group (all P<0.05). The scores of disease-related knowledge mastery, expansion of disease-related knowledge, improvement of learning interest, improvement of self-learning ability, and improvement of problem-analysis ability in the observation group were higher than those in the control group (all P<0.05). The teaching satisfaction of students in the observation group was significantly higher than that in the control group (P<0.05). 【Conclusion】 Mind map teaching method combined with case analysis method can improve assessment scores, clinical risk identification ability, and teaching outcomes of ophthalmology interns, enhance their learning interest and self-learning ability, and increase teaching satisfaction. 2026 Vol. 43 (8): 1302-1305 [Abstract] ( 4 ) HTML (1 KB)  PDF (1175 KB)  ( 1 ) 1306 Efficacy of Recombinant Human Interferon α-1b Combined with Budesonide in the Treatment of Children with Upper Respiratory Tract Infection and its Influence on Inflammatory Factors LI Xiaole DOI: 10.3969/j.issn.1671-7171.2026.08.020 【Objective】 To explore the efficacy of nebulized recombinant human interferon α-1b combined with budesonide in children with upper respiratory tract infection and its effect on inflammatory factors. 【Methods】 A total of 132 children with upper respiratory tract infection treated in Wugang Traditional Chinese Medicine Hospital from January 2023 to May 2025 were enrolled and randomly divided into control group and observation group by random number table method, with 66 cases in each group. The control group received nebulized budesonide, while the observation group was treated with nebulized budesonide combined with recombinant human interferon α-1b. The time for symptom resolution, adverse reactions, as well as the levels of inflammatory factors and immunoglobulins before and after treatment were compared between the two groups. 【Results】 After treatment, the resolution time of fever, cough, wheezing and rales in the observation group were shorter than those in the control group (all P<0.05). After treatment, serum immunoglobulin A (IgA), immunoglobulin G (IgG) and immunoglobulin M (IgM) levels in the observation group were higher than those in the control group (all P<0.05), whereas serum immunoglobulin E (IgE) level was lower. After treatment, serum interleukin-2 (IL-2) and interferon γ (IFN-γ) levels in the observation group were higher (all P<0.05), while serum interleukin-4 (IL-4) and interleukin-10 (IL-10) levels were lower (all P<0.05). The total incidence of adverse reactions in the observation group was 6.06%, which was significantly lower than 25.76% in the control group (P<0.05). 【Conclusion】 Nebulized recombinant human interferon α-1b combined with budesonide can shorten symptom resolution time, effectively regulate serum immunoglobulin and inflammatory factor levels, and presents favorable safety in children with upper respiratory tract infection. 2026 Vol. 43 (8): 1306-1308 [Abstract] ( 5 ) HTML (1 KB)  PDF (1162 KB)  ( 1 ) 1309 Effect of Naoxintong Capsule Combined with Dual Antiplatelet Therapy of Aspirin and Clopidogrel on Quality of Life in Patients with Cerebral Infarction during the Convalescent Stage HUANG Yingying, YANG Qingcheng DOI: 10.3969/j.issn.1671-7171.2026.08.021 【Objective】 To investigate the effect of Naoxintong Capsule combined with dual antiplatelet therapy of aspirin and clopidogrel (DAPT) on the quality of life in patients with cerebral infarction during the convalescent stage. 【Methods】 A total of 120 patients with cerebral infarction in the convalescent stage admitted from June 2022 to December 2024 were randomly divided into a control group (treated with aspirin and clopidogrel) and an observation group (treated with Naoxintong Capsule in addition to the control regimen), with 60 cases in each group. The therapeutic efficacy, self-care ability [Modified Barthel Index (MBI)], quality of life [Stroke Impact Scale (SIS)], and neurological function [National Institutes of Health Stroke Scale (NIHSS)] were compared between the two groups before treatment and at 1 and 3 months after treatment.【Results】 The overall response rate in the observation group was significantly higher than that in the control group (P<0.05). At 1 and 3 months after treatment, the MBI and SIS scores in the observation group were significantly higher than those in the control group(all P<0.05), while the NIHSS score in the observation group was significantly lower than that in the control group(P<0.05).【Conclusion】 Naoxintong Capsule combined with aspirin and clopidogrel DAPT can improve the overall response rate, enhance self-care ability and quality of life, and promote neurological recovery in patients with cerebral infarction during the convalescent stage. 2026 Vol. 43 (8): 1309-1311 [Abstract] ( 5 ) HTML (1 KB)  PDF (1164 KB)  ( 1 ) 1312 Application Effect of Plasma Exchange Combined with Short-Term Intensive Immunoglobulin Therapy in Severe Autoimmune Encephalitis DONG Peng, LIU Ye, WU Minlu, LIU Jieyi DOI: 10.3969/j.issn.1671-7171.2026.08.022 【Objective】 To explore the application effect of plasma exchange combined with short-term intensive immunoglobulin therapy in patients with severe autoimmune encephalitis (AE). 【Methods】 A total of 102 patients with severe AE treated in the 905th Hospital of PLA Navy were randomly divided into the control group and the observation group, with 51 cases in each group. Patients in the control group received short-term intensive immunoglobulin therapy, while those in the observation group were additionally treated with plasma exchange in addition to that in the control group. The time to symptom resolution, serum inflammatory factor levels, immune function indicators (CD3+, CD4+, CD8+) before and after treatment, and the incidence of adverse reactions were compared between the two groups. 【Results】 The time to resolution of various symptoms in the observation group was significantly shorter than that in the control group (all P<0.05). After treatment, the levels of serum inflammatory factors in the observation group were lower than those in the control group(all P<0.05), and the improvement of immune function indicators was superior to the control group (all P<0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05). 【Conclusion】 Plasma exchange combined with short-term intensive immunoglobulin therapy can significantly shorten the time to symptom resolution, reduce serum inflammatory factor levels and improve immune function in patients with severe AE, while demonstrating a favorable safety profile. 2026 Vol. 43 (8): 1312-1314 [Abstract] ( 5 ) HTML (1 KB)  PDF (1157 KB)  ( 1 ) 1315 Predictive Value of the AST/ALT Combined with Cholinesterase for Progression to Cirrhosis in Patients with Alcoholic Liver Disease YANG Fei, ZHANG Gaiyun DOI: 10.3969/j.issn.1671-7171.2026.08.023 【Objective】 To investigate the predictive value of the aspartate aminotransferase (AST)/alanine aminotransferase (ALT) combined with serum cholinesterase (ChE) for progression to cirrhosis in patients with alcoholic liver disease (ALD). 【Methods】 A total of 98 patients with ALD admitted between January 2023 and June 2024 were categorized into a cirrhosis group (n=35) and a non-cirrhosis group (n=63) according to whether cirrhosis developed. Additionally, 50 healthy volunteers were enrolled as the control group. Differences in the AST/ALT and ChE levels among the three groups were compared, and their correlations with liver stiffness measurement (LSM) and Child-Pugh class were analyzed. Receiver operating characteristic (ROC) curves were constructed to evaluate the predictive performance of these indicators for progression to cirrhosis. 【Results】 The serum AST/ALT in the cirrhosis group was higher, whereas the ChE level in the cirrhosis group was lower than those in the non-cirrhosis and control groups (all P<0.05). The serum AST/ALT was higher in patients with Child-Pugh class C than in those with class A or B (P<0.05). LSM values in the inferior segments of the right anterior and posterior hepatic lobes were higher in the cirrhosis group than in the non-cirrhosis group (P<0.05). Pearson correlation analysis showed that the AST/ALT was positively correlated with LSM in the above hepatic regions and Child-Pugh class, whereas ChE was negatively correlated with those hepatic regions and Child-Pugh class (P<0.05). The combination of the serum AST/ALT and ChE yielded an area under the curve (AUC) of 0.919 for predicting progression to cirrhosis in patients with ALD, with a sensitivity of 88.6% and a specificity of 79.4%. 【Conclusion】 An elevated AST/ALT and reduced ChE level are closely associated with cirrhotic progression in patients with ALD. The combined assessment of both AST/ALT and ChE can effectively predict the risk of cirrhosis and provide reference for early clinical intervention. 2026 Vol. 43 (8): 1315-1318 [Abstract] ( 7 ) HTML (1 KB)  PDF (1237 KB)  ( 1 ) 1319 Application Efficacy of Nifedipine Controlled-Release Tablets Combined with Fosinopril Sodium Tablets in Elderly Hypertensive Patients in Community Settings ZHAO Chunlei DOI: 10.3969/j.issn.1671-7171.2026.08.024 【Objective】 To explore the application efficacy of nifedipine controlled-release tablets combined with fosinopril sodium tablets in elderly hypertensive patients in community settings. 【Methods】 The clinical data of 80 elderly hypertensive patients treated at Kangqiao Community Health Service Center, Pudong New Area, Shanghai from September 2021 to September 2024 were retrospectively analyzed. Patients were divided into the control group (treated with fosinopril sodium tablets) and the observation group (treated with nifedipine controlled-release tablets combined with fosinopril sodium tablets) according to medication regimens, with 40 cases in each group. The clinical efficacy, diastolic blood pressure, systolic blood pressure, blood pressure control rate, renal function and incidence of adverse reactions were compared between the two groups. 【Results】 The total clinical effective rate of the observation group was 95.00% (38/40), which was higher than 72.50% (29/40) of the control group (χ2=7.440, P<0.05). After treatment, diastolic blood pressure and systolic blood pressure decreased in both groups, and were lower in the observation group than in the control group (all P<0.05). The diastolic blood pressure control rate, systolic blood pressure control rate and dual blood pressure control rate in the observation group were higher than those in the control group (all P<0.05). After treatment, blood urea nitrogen and urinary microalbumin levels declined in both groups, and were lower in the observation group (all P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups (P>0.05). 【Conclusion】 Nifedipine controlled-release tablets combined with fosinopril sodium tablets achieve favorable efficacy for elderly hypertensive patients in community settings. It can effectively improve blood pressure control rate and ameliorate renal function with good safety profile. 2026 Vol. 43 (8): 1319-1321 [Abstract] ( 5 ) HTML (1 KB)  PDF (1160 KB)  ( 1 ) 1322 Predictive Value of D-Dimer-to-Fibrinogen Ratio for Progressive Cerebral Infarction GUO Yanli, LIU Shuang, LEI Pei DOI: 10.3969/j.issn.1671-7171.2026.08.025 【Objective】 To investigate the predictive value of the D-dimer-to-fibrinogen ratio (DFR) at admission for progressive cerebral infarction. 【Methods】 A total of 92 patients with acute cerebral infarction admitted to our hospital from February 2022 to May 2025 were enrolled. The levels of D-dimer and fibrinogen were measured at admission, and the DFR was calculated. The National Institutes of Health Stroke Scale (NIHSS) scores were assessed at admission and 72 h after admission. Progressive cerebral infarction was defined as an increase of ≥4 points in the NIHSS score within 72 h (the progression group). The differences in DFR between the progression group and non-progression group were compared. Multivariate Logistic regression analysis was performed to evaluate the correlation between DFR and progressive cerebral infarction. Receiver operating characteristic (ROC) curves were plotted to assess the predictive performance of DFR. 【Results】 Among the 92 patients, 22 developed progressive cerebral infarction, accounting for 23.91%. The DFR in the progression group was significantly higher than that in the non-progression group (P<0.05). Multivariate logistic regression analysis showed that, after adjustment for confounding factors including age, baseline NIHSS score, history of atrial fibrillation, and intravenous thrombolysis, DFR ≥0.27 remained an independent predictor of progressive cerebral infarction (OR=4.908, P<0.05). ROC curve analysis showed that the AUC of DFR for predicting progressive cerebral infarction within 72 h was 0.859 and the optimal cutoff value was 0.27, with a sensitivity of 77.3% and a specificity of 78.6%. 【Conclusion】 An elevated DFR at admission is associated with an increased risk of progressive cerebral infarction within 72 h. DFR has certain predictive value for progressive cerebral infarction and may serve as an auxiliary indicator for early risk stratification in patients with acute cerebral infarction. 2026 Vol. 43 (8): 1322-1325 [Abstract] ( 5 ) HTML (1 KB)  PDF (1223 KB)  ( 1 ) 1326 Effect of Different Administration Routes of Gastrodin Combined with Piracetam on Prognosis in Patients with Acute Cerebral Infarction WANG Chen DOI: 10.3969/j.issn.1671-7171.2026.08.026 【Objective】 To investigate the effects of different administration routes of gastrodin combined with piracetam on the prognosis of patients with acute cerebral infarction (ACI). 【Methods】 A total of 94 patients with ACI admitted to Luodian Town Health Center of Runan County from August 2022 to August 2024 were randomly divided into an observation group and a control group, with 47 patients in each group. The observation group received intravenous infusion of gastrodin combined with piracetam, while the control group received intramuscular injection of gastrodin combined with piracetam. Clinical efficacy, incidence of adverse reactions, hemorheological parameters, inflammatory factor levels before and after treatment, and follow-up outcomes at 3 months, including activities of daily living [Activities of Daily Living Scale (ADL) score], neurological function [National Institutes of Health Stroke Scale (NIHSS) score], were compared between the two groups. 【Results】 The overall effective rate in the observation group was 93.62%, which was significantly higher than 78.72% in the control group (P<0.05). After treatment, the levels of low-shear whole blood viscosity, high-shear whole blood viscosity, and plasma viscosity in the observation group were significantly lower than those in the control group (P<0.05). The levels of interleukin-2 (IL-2), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) in the observation group were significantly lower than those in the control group (P<0.05). The total incidence of adverse reactions in the observation group was lower than that in the control group, but the difference was not statistically significant (P>0.05). After 3 months of follow-up, the NIHSS score in the observation group was lower, while the ADL were higher than those in the control group (P<0.05). 【Conclusion】 Gastrodin combined with piracetam is effective and relatively safe for the treatment of ACI. However, intravenous administration provides better therapeutic efficacy and prognosis than intramuscular injection. 2026 Vol. 43 (8): 1326-1328 [Abstract] ( 5 ) HTML (1 KB)  PDF (1160 KB)  ( 1 ) 1329 Effect of Comprehensive Auricular Point Therapy on Pain Severity and Sleep-Wake Disorders in Patients with Cervicogenic Headache SANG Weiqun, NIU Chaoyang, WANG Zhaojuan, HU Wenjing, LIU Lili DOI: 10.3969/j.issn.1671-7171.2026.08.027 【Objective】 To analyze the effect of comprehensive auricular point therapy on pain degree and sleep-wake disorder in patients with cervical episodic headache (CEH). 【Methods】 A total of 60 CEH patients treated in our hospital from July 2023 to January 2025 were randomly divided into the control group and the observation group, with 30 cases in each group. The control group received routine nursing, and the observation group received routine nursing combined with comprehensive auricular point therapy (auricular vein bloodletting, auricular point pricking, and auricular point pressing with cowherb seed). The pain degree [headache duration, headache frequency, Visual Analogue Scale (VAS)], cervical spine function [Neck Disability Index (NDI), Range of Motion (ROM)], sleep-wake disorder [Pittsburgh Sleep Quality Index (PSQI)] and quality of life were compared between the two groups before and after intervention. 【Results】 After 4 weeks of intervention, the headache duration of the observation group was shorter than that of the control group, and the headache frequency, VAS score, NDI score, cervical ROM score and each dimension score of PSQI were lower than those of the control group (all P<0.05). The total nursing satisfaction rate of the observation group was significantly higher than that of the control group (P<0.05). 【Conclusion】 Comprehensive auricular point therapy can effectively shorten the headache duration, reduce headache frequency and pain degree, improve cervical spine activity and sleep quality, and enhance nursing satisfaction in CEH patients, which is worthy of clinical promotion. 2026 Vol. 43 (8): 1329-1332 [Abstract] ( 6 ) HTML (1 KB)  PDF (1182 KB)  ( 1 )

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