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Quick Search     Adv Search 2017 Vol. 34, No. 4 Published: 2017-04-30 Article          Article 625 Study on the Relationship between Serum Vitamin D level and Blood Cholesterol in Healthy Pregnant Women TIAN Yi-ming, WU Dong-mei, GAO Guo-qin,et al DOI: 10.3969/j.issn.1671-7171.2017.04.001 【Objective】To evaluate the relationship between serum vitamin D level and blood cholesterol in healthy pregnant women at 24~28 weeks of gestation.【Methods】Ninety-one healthy pregnant women with 24~28 weeks gestation were enrolled as the experimental group, and sixty-three non-gestational healthy women were recruited as the control group. All cases were from our hospital from May 2012 to August 2013. General information (name, age, height, weight, gestational weeks) and clinical data (triglyceride/TG, low-density lipoprotein cholesterol/LDL-C, high-density lipoprotein cholesterol/HDL-C, total cholesterol/TC and serum vitamin D [25 (OH) D] levels were collected, and the relation between blood cholesterol and serum vitamin D was analyzed.【Results】There was no significant difference between the experimental group and the control group (P>0.05). The BMI of the experimental group was significantly higher than that of the control group (P<0.001). The level of serum 25 (OH) D in the experimental group was significantly lower than that in the control group (P<0.001), while levels of serum TG, TC, HDL-C and LDL-C were significantly higher than those in the control group (P<0.05). The level of 25 (OH) D in the experimental group was significantly negatively correlated with TC (r=-0.397,P=0.039) and LDL-C (r=-0.301,P=0.041). However, it did not show significant correlation with age, BMI, TG, and HDL-C (P>0.05).【Conclusion】Serum vitamin D level is significantly related to the blood cholesterol in women at middle gestational period. 2017 Vol. 34 (4): 625-627 [Abstract] ( 134 ) HTML (1 KB)  PDF  (0 KB)  ( 18 ) 628 Clinical Efficacy of Atorvastatin on Diabetic Patients with Hypertension and its Effects on Urinary β2-MG, SCr and HbAlc Levels JIANG Li-hua, HAN Xiao-jun, SU Ru-ting DOI: 10.3969/j.issn.1671-7171.2017.04.002 【Objective】To investigate the clinical effects of atorvastatin in the treatment of diabetic patients with hypertension and its effects on levels of urine β2 microglobulin (β2-MG), serum creatinine (Scr) and glycosylated hemoglobin (HbA1c). 【Methods】Eighty-six patients with diabetes and hypertension were randomly divided into the control group and the observation group, with 43 cases in each group. The control group was given conventional symptomatic treatment, while the observation group was additionally treated with atorvastatin. The therapeutic effects were compared between the two groups. The changes of levels of urine β2-MG, Scr, HbA1c, total cholesterol (TC), triacylglycerol (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), high-sensitivity C reactive protein (hs-CRP), and interleukin -6 (IL-6) before and after treatment were determined; the incidence of adverse reactions was statistically analyzed. 【Results】 The total effective rate was 95.35% (41/43) in the observation group, which was higher than that in the control group (79.70%, 34/43); the difference was statistically significant (χ2=5.107,P=0.023). Before treatment, the indexes showed no significant differences between the two groups (P>0.05). After treatment, the levels of β2-MG, Scr, HbA1c, TC, LDL-C, IL-6, and hs-CRP decreased P<0.05)-the decrease in the observation group was greater than that in the control group (all P<0.05). 【Conclusion】 Atorvastatin is effective in the treatment of diabetic patients with hypertension. It can reduce the levels of blood lipids and inflammatory factors as well as improve renal function. 2017 Vol. 34 (4): 628-631,634 [Abstract] ( 142 ) HTML (1 KB)  PDF  (0 KB)  ( 14 ) 631 Pharmacokinetic Research of Cefathiamidine for Patients with Hysterectomy under Lumbar-epidural Anesthesia Based on the Urine Drug Method SHE Zhi-hua, WU Wei DOI: 10.3969/j.issn.1671-7171.2017.04.003 【Objective】To provide references for clinical administration, the excretion of cefathiamidine in patients with hysterectomy under lumbar-epidural anesthesia was studied.【Methods】Thirteen eligible patients with hysterectomy under lumbar-epidural anesthesia, ASA grade Ⅰ~Ⅲ, were selected. The operation lasted about 3 hours. Cefathiamidine was intravenously dripped in patients with hysterectomy under lumbar-epidural anesthesia for one hour; urine samples from 0~1 h、1~2 h、2~3 h、3~4 h、and 4~5 h after drug administration were collected and measured with HPLC-UV. WinNonlin6.1 software package was used for pharmacokinetic analysis.【Results】T1/2β in the lumbar-epidural anesthesia group was 1.95±0.97h, whereas T1/2β in the non-anesthesia group was (1.12±0.44)h. There was a significant difference between lumbar-epidural anesthesia group and the non-anesthesia group(P<0.05). The urinary average excretion rate of cefathiamidine detected within 0~6 hours showed that the peak was at 1.5 hours after the drug was administered in both the anesthesia and non-anesthesia groups. The average excretion rate of cefathiamidine in non-anesthesia condition was higher than that in anesthesia conditions. The average cumulative excretion rate of cefathiamidine in urine of the non-anesthesia group was significantly faster than that of the anesthesia group.【Conclusion】 T1/2β of cefathiamidine in lumbar-epidural anesthesia group was significantly higher than non-anesthesia group. This indicates that the body's stress response caused by anesthesia, perioperative medication, and surgical trauma could affect the excretion of drugs in the body and prolong the drug's half-life. 2017 Vol. 34 (4): 631-634 [Abstract] ( 108 ) HTML (1 KB)  PDF  (0 KB)  ( 14 ) 635 Effect of different storage duration of Urine Specimens on Urinary Sediment Related Indexes HOU Ling, CHENG Jun-li, LIU Reng,et al DOI: 10.3969/j.issn.1671-7171.2017.04.004 【Objective】 To investigate the effect of different storage duration of urine specimens on urinary sediment in routine urine test. 【Methods】The urinary sediment were collected and related indexes detected at 1h, 2h, 4h and 6h of storage. The changes in morphology of red blood cells were observed at different time points. 【Results】Under 4℃ room temperature , the red blood cell count, urinary cast count and macrocyte count after 4h and 6h of storage were significantly lower than those at immediate collection while lysed erythrocytes were increased (P<0.05). Under room temperature and 4℃, the white blood cell count after 6h of storage was significantly lower than that at immediate collection (P<0.05). The epithelial cell count and microcyte count showed no significant differences at different time points (P>0.05). 【Conclusion】The storage duration of urine specimens has great effect on the examination results of urinary sediment. It is suggested that the examination be completed within 4h after collection of specimens . The storage temperature has little effect on red blood cells, white blood cells and urinary cast count. 2017 Vol. 34 (4): 635-637,640 [Abstract] ( 85 ) HTML (1 KB)  PDF  (0 KB)  ( 16 ) 637 Correlation Study between Heart Rate Variability and Short Ventricular Tachycardia in Patients with Chronic Heart Failure TAO Zhen-zhu, OU Bai-qing, DENG Ting-zhi DOI: 10.3969/j.issn.1671-7171.2017.04.005 【Objictive】To monitor heart rate variability (HRV) and non sustained ventricular tachycardia (NSVT) in patients with chronic heart failure (CHF) by by prolonged Holter(72h ) and analyze their correlation.【Methods】The clinical data of 80 patients with chronic heart failure admitted to Hunan People's Hospital from March 2016 to September 2016 were selected, and their continuous 72h dynamic electrocardiogram was monitored, and they were divided into NSVT group (n=30) and no NSVT group according to whether NSVT was detected; the differences between the HRV indicators, and correlation between NSVT and HRV indexes at 24 h, 48 h, 72 h were analyzed.【Results】The time domain indexes in the SVT group were lower than those without NSVT group, but the difference of only 24 h standard deviation (SDNN) of all sinus R-R interval of the two groups was statistically significant (P<0.01); There was no significant difference between the two groups in the low frequency power (VLF), low frequency power (LF) and high frequency power (HF) in the frequency domain(mean P＞0.05), NSVT in the group LF/HF was significantly higher than that in the NSVT group, the difference was statistically significant (P<0.05).The time domain and frequency domain indexes of HRV were significantly correlated with SDNN, LF/HF and NVST at 24 h and 72 h, respectively; 48 h SDNN ,root mean square of successive differences (RMSSD), PNN50 and LF/HF were significantly corelated with NSVT; SDNN and NSVT were only moderately correlated with NSVT in 48 h, Other indicators were associated with NSVT lowly. With the aggravation of heart failure, the detection rate of NSVT showed an increasing trend, and the SDNN value was decreased, the difference of NYHA cardiac function grade Ⅱ,Ⅲ and Ⅳ was statistically significant (P<0.01).【Conclusion】HRV is correlated with NSVT in CHF patients by 72h Holter, and the decrease of SDNN and the increase of LF/HF can be predictors of NSVT to evaluate the prognosis of patients with heart failure. 2017 Vol. 34 (4): 637-640 [Abstract] ( 54 ) HTML (1 KB)  PDF  (0 KB)  ( 17 ) 641 Meta-Analysis of Sleep Quality for Hospitalized Patients in China DING Jiu-hong, GUO Wen-hui, CAI Yi-min,et al DOI: 10.3969/j.issn.1671-7171.2017.04.006 【Objective】To evaluate the effect on the quality of sleep in hospitalized patients. 【Methods】Data related to sleep quality of hospitalized patients were retrieved from different resources (CNKI,VIP,Wanfang and Duxiu) and collected from 1990 to 2016. RevMan5.3 software was used for statistical processing. 【Results】A total of 5 articles were included in the meta-analysis. The results showed that Pittsburgh sleep quality index scale (PSQI) scores in the experimental group was higher than those in the control group [random effects model, WMD=3.2,95%CI (2.21,4.18),P<0.001]. Scores of seven dimensions in PSQI of the experimental group were higher than those of the control group. 【Conclusion】The sleep quality of hospitalized patients was worse than that of non-hospitalized healthy examinees. 2017 Vol. 34 (4): 641-644 [Abstract] ( 62 ) HTML (1 KB)  PDF  (0 KB)  ( 16 ) 645 Short-term Prognosis of Anterior Cruciate Ligament Combined with Meniscus Injury Treated by Arthroscopic Surgery ZENG Zhao-chi, CHEN Bin, YANG Bo,et al DOI: 10.3969/j.issn.1671-7171.2017.04.007 【Objective】To analyze short-term prognosis of arthroscopic surgery for the treatment of anterior cruciate ligament (ACL) combined with meniscus injury in youth and to explore its clinical application value. 【Methods】A total of 129 cases of youth with ACL and meniscus injury from May 2014 to May 2016 were collected for the study. Patients were classified according to O 'annr FLF and were all treated by arthroscopic surgery. Subjective evaluation of knee scores based on the criteria of international knee document committee council (IKDC) and Lysholm were recorded at preoperation and at 3 months postoperation. Clinical efficacy and short-term prognosis among patients with different meniscus injuries were compared and statistically analyzed.【Results】Arthroscopy was successfully implemented on all 129 patients (open surgery was not necessary), and the postoperative recovery was good (phaseⅠhealing of incision) at the 3-month follow-up. No serious complications occurred. The scores of both IKDC and Lysholm among patients with different O 'annr FLF classifications were higher at 3-moth postoperation than those at preoperation; the differences were statistically significant (P<0.05). The patients' knee activities restored to normal within 3 months after surgery without pain, swelling or joint lock symptoms. Patients with longitudinal crack knees according to O 'annr FLF classification had better results compared to those of other classifications, and the difference was statistically significant (P<0.05). 【Conclusion】Arthroscopic surgery on different classifications of ACL combined with meniscus injury can achieve very good short-term prognosis without serious complications. It is a safe and effective way to treat ACL with meniscus injury in youth. 2017 Vol. 34 (4): 645-648 [Abstract] ( 71 ) HTML (1 KB)  PDF  (0 KB)  ( 16 ) 648 Effect of Sufentanil on Anesthesia of Painless Artificial Abortion and Hemodynamics BAI Wen-jun, MA Tao DOI: 10.3969/j.issn.1671-7171.2017.04.008 【Objective】To investigate the effect of sufentanil on anesthesia of painless artificial abortion, the degree of uterine pain and hemodynamics.【Methods】One hundred and forty cases of artificial abortion were randomly divided into sufentanil group (group A) and fentanyl group (group B), each with 80 cases; the anesthetic effect of the two groups,the mean arterial pressure (MAP) , heart rate(HR), arterial blood pressure saturation (SpO2) and respiratory rate (RR) before anesthesia, after anesthesia (T1), 2min (T2), expanding Palace (T3), surgery (T4) and postoperative changes of uterine pain were compared.【Results】The monitoring values of MAP, HR, SpO2, RRv of the two groups of patients at T1 were not significantly different (P>0.05); The MAP, HR, SpO2, RR values of group A at T1 and T2 were higher than those of group B (P<0.05); In group A, the effect of anesthesia was 81.25%, which was significantly higher than that in group B (67.50%), and the difference between the two groups was significant (P<0.05);At each time point after operation, the VAS scores of the patients in the group A were lower than those in the group B (P<0.05), and the Ramsay score 5min post operation of the group A was better than that of the group B (P<0.05).【Conclusion】The application of sufentanil in painless artificial abortion has the advantages of good anesthetic effect, little influence on hemodynamics of patients, and good sedative and analgesic effect. 2017 Vol. 34 (4): 648-650 [Abstract] ( 66 ) HTML (1 KB)  PDF  (0 KB)  ( 15 ) 651 Changes and Differential Diagnosis of Biochemical Markers related to Tuberculous and Malignant Pleural Effusion ZHANG Ning, WANG Ke, ZHANG Xia DOI: 10.3969/j.issn.1671-7171.2017.04.009 【Objective】To investigate the changes in biochemical markers between tuberculous pleural effusion (TPE) and malignant pleural effusion (MPE) for their significance in making differential diagnosis. 【Methods】A total of 92 pleural effusion cases were collected from January 2012 to January 2016 at our hospital. Among them, there were 52 cases of TPE and 40 cases of MPE. At admission, 5ml of pleural effusions was harvested by pleural biopsy. Routine examination of pleural effusion (white blood cells, lymphocytes, neutrophils, eosinophils, mesothelial / tissue cells, total protein, lactate dehydrogenase, glucose) and cytokines [IL-1β, IL-10, IL-13, IFN-gamma, chemokines interferon inducible protein 10 (IP-10), basic fibroblasts Cell growth factor (bFGF)]were tested. 【Results】The number of white blood cells in pleural effusion was significantly higher in TPE patients than in MPE patients (P<0.05). However, in MPE and TPE patients, the number of pleural effusion lymphocytes, neutrophils, eosinophils, mesothelial, Lactate dehydrogenase (LDH) and glucose were not statistically significant. The levels of IL-1β, IP-10, IL-13 and IFN-γ in tuberculous pleural effusion were significantly higher than those in malignant pleural effusion. The level of bFGF in malignant pleural effusion was significantly higher than that in tuberculous pleural effusion. There were no significant differences in IL-10 levels in both pleural fluids. ROC curve analysis showed that when the optimal thresholds were 5.5 pg/mL for IL-1β, 4005 pg/mL for IP-10, 7.9 pg/mL for IL-13, 100.5 pg/mL for IFN-γ and 2.4 pg/mL for bFGF (P<0.05), which was valuable in the diagnosis of tuberculous and malignant pleural effusion. 【Conclusion】The changes of IL-1β, IP-10, IL-13, IFN-γ and bFGF have important differential diagnostic value in tuberculous and malignant pleural effusion. 2017 Vol. 34 (4): 651-654,657 [Abstract] ( 54 ) HTML (1 KB)  PDF  (0 KB)  ( 14 ) 654 Relationship Study Between the Heat Shock Protein 70 (HSP70) and Activation of TLR4 Signaling Pathway in Peripheral Blood Mononuclear Cells In Unstable Angina Pectoris Patients SHENG Fu-qiang, HE Mao-rong, ZHANG Mei-lin, et al DOI: 10.3969/j.issn.1671-7171.2017.04.010 【Objective】To evaluate relationship between the heat shock protein 70 (HSP70) and the activation of TLR4 signaling pathway in peripheral blood mononuclear cells in unstable angina pectoris (UAP) patients.【Methods】The clinical data of 30 patients with UAP and 30 cases with stable angina pectoris (SAP) who were admitted to our hospital from December 2014 to March 2016 were selected and divided into UAP group and SAP group . At the same time, 30 patients with suspected acute coronary syndrome (ACS) who were admitted to our hospital in the same period of time were selected as control group who showed a normal coronary artery after coronary angiography. The levels of HSP70 in peripheral blood serum and monocyte NF-κB p65 levels were detected by ELISA.Flow cytometry was used to detect the expression of TLR4 in peripheral blood mononuclear cells of each group, and the correlation of the parameters of each group was analyzed by order.【Results】Levels of HSP70, the positive rate of TLR4 expression in monocytes and the monocyte nuclear protein NF-κB p65 in the UAP group were higher than those in the SAP group and the control group, the difference was statistically significant (mean P<0.05); the positive expression rate of TLR4 in peripheral blood mononuclear cells of the SAP group was significantly higher than that of the control group, the difference was statistically significant (P<0.05). The HSP70 level in peripheral blood serum of the UAP group was significantly correlated with the positive expression rate of TLR4 and the nuclear protein NF-κB p65 (P<0.05) ; the positive expression rate of TLR4 was significantly correlated with the nuclear protein NF-κB p65 (P<0.05); There was no significant correlation on the above indexes between the SAP group and the control group (22) (P>0.05).【Conclusion】HSP70 may be involved in the activation of TLR4 signaling pathway in peripheral blood mononuclear cells of UAP patients, through the expression of monocyte TLR4 receptor. 2017 Vol. 34 (4): 654-657 [Abstract] ( 72 ) HTML (1 KB)  PDF  (0 KB)  ( 16 ) 658 CT Image Measurement and its Clinical Significance of Vertebral Height in Patients with Thoracolumbar Burst Fracture GUO Ke-miao, LI Jing DOI: 10.3969/j.issn.1671-7171.2017.04.011 【Objective】To investigate the significance of the degree of vertebral height loss and the degree of recovery of vertebral body height after operation and the clinical significance by measuring the size of the gap left by the bone defect in the thoracolumbar spine burst fracture before and after operation in CT images.【Methods】A retrospective review was made based on imaging material of forty patients who accepted posterior restoration and instrumentation through pedicle-screw implant technique because of thoracic or lumbar spine burst fracture. The preoperative and postoperative computed tomography (CT) scans were performed for each case, mid-sagittal or para-mid-sagittal scans were selected to measure the preoperative minimal residual vertebral body height (Pre-VBH), postoperative maximal vertebral body height restoration ( Po-VBH) and the maximal vertical gap-height (GH) within the restored vertebral body; the relationship between GH and Pre-VBH, Po-VBH was analyzed. At the same time, 15 cases of internal fixation fracture caused by nonunion of vertebral fracture were analyzed retrospectively in order to explore the critical value of the percentage of vertebral compression, because of the too large gap in the vertebral body resulting in fracture nonunion.【Results】 Preoperative minimal residual vertebral body height (Pre-VBH) ranged from 20.8% to 60%, averaged 48.2%; postoperative maximal vertebral body height restoration (Po-VBH) was 71.5%~127.3%, averaged 93.3%; difference between Po-VBH and Pre-VBH was 21.4%~79.1%, averaged 45.7%; the maximal vertical gap-height (GH) within the restored vertebral body was 19.3%~76.7%, averaged 45.3%. Statistical analysis demonstrated there was no significant difference between the value of Po-VBH minus Pre-VBH and the value of GH. The value of gap-height in restored vertebral body measured and calculated in 15 failed cases of bone nonunion ranged from 44.5% to 67.5%. 【Conclusion】 Accompanying the restoration of compressed vertebral body height, there is always vertical gap left within the fractured vertebral body, the height of vertical gap is nearly equal to postoperative maximal vertebral body height restoration (Po-VBH) minus Preoperative minimal residual vertebral body height (Pre-VBH),which can facilitate us to formulate a formula: postoperative gap height (GH)≌(Po-VBH)- (Pre-VBH). If the value of the gap-height within restored vertebral body is 44.5% more than the height of vertebral body after fracture reduction, bone nonunion may be an inevitable result for thoracic or lumbar burst fracture. 2017 Vol. 34 (4): 658-663 [Abstract] ( 85 ) HTML (1 KB)  PDF  (0 KB)  ( 14 ) 663 Clinical Research on Ten Blindly Ginseng and Astragalus Capsule in the Failure of Two Qi Type of Digestive Tract Malignant Tumor after Chemotherapy WU Wen-bo, SUN Li-zheng DOI: 10.3969/j.issn.1671-7171.2017.04.012 【Objective】 To explore the clinical effects of Ten blindly ginseng and astragalus capsule on the two qi type of digestive tract malignant tumor after chemotherapy. 【Methods】 Ninety cases of patients with the failure of two qi type of digestive tract malignant tumor treated in our hospital were selected and were divided randomly into the observation group and the control group,45 cases in each group. The two groups of patients were given chemotherapy treatment. The control group was given with the shark liver alcohol drug for treatment, while the observation group was given with shark liver alcohol plus ten blindly ginseng and astragalus capsule drug therapy. The quality of life, the main side reactions of drug and the decrease in the white blood cell count of the two groups were compared. 【Results】The total effective rate of the observation group 73.33% (33/45) was higher than that the control group 42.22% (19/45) (P<0.05); White blood cells of the two groups decreased on the different degrees after treatment, but the decrease ratio in the control group was obviously higher than that of the observation group, the difference was significant (P<0.05). The quality of life of patients in the observation group was obviously higher than that of the control group after treatment (P<0.05). 【Conclusion】The Ten blindly ginseng and astragalus capsule can reduce the side effects on patients with the failure of two qi type of digestive tract malignant tumor after chemotherapy by improving the quality of life of patients and is worth clinical application . 2017 Vol. 34 (4): 663-665 [Abstract] ( 59 ) HTML (1 KB)  PDF  (0 KB)  ( 16 ) 666 Study on Ectopic Bone Formation of Osteoblastic-Induced hUCMSCs Composite with nHA/PA66 Material CHEN Gang, LIAO Qian-de, HU You-wei,et al DOI: 10.3969/j.issn.1671-7171.2017.04.013 【Objective】To explore the ability of ectopic bone formation of osteoblastic-induced hUCMSCs composite with nHA/PA66 material in nude mouse back and provide theories foundation for further large animal experiments of bone tissue engineering.【Methods】Human umbilical cord mesenchymal stem cells were seeded into nHA/PA66 scaffolds and cultured in vitro; HUCMSCs suspension, nHA/PA66 scaffold material, osteogenic-induced hUCMSCs and nHA/PA66 scaffold composite were implanted into the dorsal muscle pouch of nude mice; the ectopic bone formation was observed. The expression of HE staining and osteocalcin immunohistochemical staining were observed after operation, and the osteogenic ability was observed by scanning electron microscope.【Results】Neither osteoblastic-induced hUCMSCs nor nHA/PA66 material were sclerotized in the muscular pouch of nude mouse back. The osteoblastic-induced hUCMSCs + nHA/PA66 were maturely sclerotized in large amount,the material partly degradated.【Conclusion】 The biological properties of the composites prepared by the combination of hUCMSCs and nHA/PA66 scaffolds in the nude mice have ectopic osteogenesis. 2017 Vol. 34 (4): 666-670,672 [Abstract] ( 64 ) HTML (1 KB)  PDF  (0 KB)  ( 15 ) 670 Characteristics of Color Doppler Ultrasonography and Its Diagnostic Value of Thyroid Carcinoma ZHONG Xiao-li, ZENG Hui-fen, SONG Xiu-lian,et al DOI: 10.3969/j.issn.1671-7171.2017.04.014 【Objective】 To investigate the characteristics of color Doppler ultrasonography (CDFI) in the differential diagnosis of thyroid carcinoma. 【Methods】A retrospective analysis of the CDFI data of 137 patients (169 nodules) which were confirmed by pathological examination in our hospital. Among them, there were 82 cases (101 nodules) of thyroid carcinoma and 55 patients (68 nodules) with benign thyroid nodules. CDFI features of thyroid carcinoma nodules and benign nodules were compared to reveal its diagnostic value to identify benign and malignant nodules.【Results】The rate of nodal fuzzy boundaries, calcification rate, low echo rate, grade Ⅱ~Ⅲ blood flow rate, rate of resistance index (RI)<0.7, lymph node enlargement rate were 61.39%, 76.24%, 74.26%, 66.34%, 62.38%, 45.54%, respectively, in thyroid cancer nodules. These were higher than those of the benign nodules 16.18%, 27.94%, 26.47%, 25%, 35.29%, 11.76%, respectively. The differences were statistically significant (P<0.05). Thyroid cancer nodules appeared 35.64% of halo rate and 31.68% of rear attenuation rate, which were lower than those of benign nodules (75%, 55.88%, respectively) and the difference was statistically significant (P<0.05). The sensitivity of CDFI in differential diagnosis of thyroid cancer nodules was 77.23%, the specificity was 80.88%, and the missed diagnosis rate was 22.77%, the misdiagnosis rate was 19.12%.【Conclusion】There are significant differences in CDFI features between benign and malignant thyroid nodules, which is of great value in the differential diagnosis of thyroid carcinoma. 2017 Vol. 34 (4): 670-672 [Abstract] ( 44 ) HTML (1 KB)  PDF  (0 KB)  ( 13 ) 673 Correlation between Heart Rate Variability , Blood Pressure Variability and Vascular Injury in Patients with Essential Hypertension LIAO Die, ZHOU Hua DOI: 10.3969/j.issn.1671-7171.2017.04.015 【Objective】 To investigate the correlation between heart rate variability, blood pressure variability and vascular injury in patients with essential hypertension.【Methods】The clinical data of 405 patients with essential hypertension admitted to our hospital from June 2013 to June 2016 were retrospectively analyzed. According to their brachial ankle pulse wave velocity (baPWV), the patients were divided into baPWV normal group (baPWV < 14 m/s,n=267) and baPWV raising group (baPWV=14 m/s,n=138). All patients were monitored with 24 h dynamic electrocardiogram, and the heart rate variability was analyzed using time domain and frequency domain analysis; Ambulatory blood pressure was monitored in all the patients, and the heart rate variability and blood pressure variability were compared between the two groups to analyze the correlation with vascular injury.【Results】The standard deviation (SDANN) of the mean value of RR interval of every 5 min in patients thebaPWV normal group was higher than that in the baPWV raising group; Low frequency (LF), high frequency (HF), low frequency / high frequency (LF/HF), night / day heart rate (nHR/dHR) was lower than that of the baPWV raising group, the difference was statistically significant (P<0.05).24 h average pulse pressure (24hPP), 24 h mean systolic blood pressure (24hSBP), daytime average systolic blood pressure (dSBP), the mean pressure (dPP), nocturnal mean systolic blood pressure (nSBP), 24 h systolic blood pressure standard deviation (24hSSD) of the BaPWV normal group were lower than those of the baPWV raising group, the rate of nocturnal systolic blood pressure (SBPF) was higher than that of the baPWV raising group, the difference was statistically significant (P<0.05). LF, LF/HF, nHR/dHR, 24hPP and 24hSSD showed significant positive correlation with baPWV (P<0.05). 【Conclusion】LF, LF/HF, nHR/dHR, 24hPP and 24hSSD are significantly positively correlated with baPWV in patients with essential hypertension, which means that heart rate variability and blood pressure variability are significantly correlated with vascular injury in patients with essential hypertension. 2017 Vol. 34 (4): 673-676,679 [Abstract] ( 79 ) HTML (1 KB)  PDF  (0 KB)  ( 15 ) 676 Comparison of Interim Efficacy of Different Surgical Procedures in the Treatment of Ossification of Posterior Longitudinal Ligament of Cervical Spine WANG Shuai, LI Xian-zhou, GUO Hong-min,et al DOI: 10.3969/j.issn.1671-7171.2017.04.016 【Objective】To explore the interim efficacy of different surgical procedures in the treatment of ossification of posterior longitudinal ligament of cervical spine. 【Methods】Ninety-three cases of ossification of posterior longitudinal ligament of cervical spine treated in our hospital from January 2013 to January 2016 were selected. Twenty-seven patients underwent anterior cervical vertebral subtotal resection combined with bone grafting internal fixation as group A. 34 patients underwent posterior single open-door vertebral canal enlargement laminoplasty as group B, and 32 patients underwent total internal fixation with vertebral decompression and lateral mass screw fixation as group C. The Japanese Orthopedic Association (JOA) 17-point method was used to evaluate patients' neurological function and JOA scores before and 1 month after operation. (ROM) percentages and visual analogue scale (VAS) were compared between the three groups after one month. 【Results】The neurologic improvement was found : Excellent in 4 patients (14.8%), Good in 7 patients (25.9%), Fair in 12 patients (44.4%) and Poor in 4 patients (14.8%); 6 patients(17.6%) were found Excellent in the group B, 12 cases (35.2%) Good, 11 cases (32.4%) Fair and 5 cases (14.7%) Poor. The Group C found Excellent in 7 cases (21.9%), Good in 10 cases (31.3%), Fair in 11 cases(34.4% and Poor in 4 cases (12.5%). Neurological improvement rate of three groups of patients was equivalent ; the level of the group A was lower , the difference was statistically significant (P<0.05). Comparison of the incidence of axial symptoms, ROM percentage and VAS score of the three groups of patients found that the group C had lower incidence of axial symptoms, higher ROM percentile and lower VAS score, the difference was statistically significant (P<0.05).【Conclusion】Posterior cervical spine surgery is recommended for patients with ossification of the posterior longitudinal ligament of the cervical spine. The internal fixation of vertebral lamina decompression and lateral mass screw fixation can improve the rate of neurological improvement and decrease the degree of pain. 2017 Vol. 34 (4): 676-679 [Abstract] ( 65 ) HTML (1 KB)  PDF  (0 KB)  ( 17 ) 680 Clinical Efficacy of Sequential Chemoradiotherapy and Concurrent Chemoradiotherapy in the Treatment of Advanced Gastric Cancer LIN Xiao-ming, LIANG Rong, LI Shu-hui,et al DOI: 10.3969/j.issn.1671-7171.2017.04.017 【Objective】To investigate the clinical efficacy of sequential chemoradiotherapy and concurrent chemoradiotherapy in the treatment of advanced gastric cancer.【Methods】 One hundred and sixty patients with gastric cancer after radical operation were randomly divided into two groups, the observation group was treated with adjuvant chemotherapy after the 4 cycles of intensity modulated radiation therapy, the control group was treated with radiotherapy and chemotherapy at the same time, the efficacy of the two groups were compared between the two groups.【Results】The survival rate of the observation group was 87.50%, 76.25%,53.75%(43/80) respectively, which were significantly higher than those in the control group (73.75%, 60%,37.50%) (P<0.05);There was no significant difference in the incidence of complications such as fever, gastrointestinal reaction, liver and kidney dysfunction in the observation group compared with the control group (P>0.05). In the observation group, the recurrence rate was 26.25% (21/80), which was significantly lower than that in the control group (40/80), and the difference was significant (P<0.05).【Conclusion】In the treatment of advanced gastric cancer, sequential radiotherapy is more effective than the concurrent radiotherapy and chemotherapy, and the recurrence rate is low, so it is worthy of popularization and application. 2017 Vol. 34 (4): 680-681 [Abstract] ( 55 ) HTML (1 KB)  PDF  (0 KB)  ( 14 ) 682 Clinic Effects of Serum and Cerebrospinal Fluid Procalcitonin (PCT) Detection in Central Nervous System Treatment of Infectious Diseases ZHANG Qing-sheng, LI Shu-fang, ZENG Wen-gang DOI: 10.3969/j.issn.1671-7171.2017.04.018 【Objective】 To investigate clinic effects of serum and cerebrospinal fluid procalcitonin (PCT) detection in central nervous system treatment of infectious diseases. 【Methods】 Sixty cases of patients for treatment of encephalitis were selected as the observation group (20 cases of the viral, 20 cases of the suppurative and 20 cases of the tuberculosis ) , at the same time 20 cases of headache patients who were hospitalized but excluded encephalitis were selected as the control group. All patients were detected in the serum and CSF PCT concentration on admission, 3d and 7 d after treatment. At the same time, cerebrospinal fluid cell number and other relevant data were recorded.【Results】 The serum PCT concentration of the suppurative encephalitis group was significantly higher than that in other groups, the difference was statistically significant (P<0.05); after treatment, serum PCT concentration of the suppurative encephalitis group decreased, the difference was statistically significant (P<0.05); before and after treatment, the differences of serum and cerebrospinal fluid PCT concentration of the viral encephalitis group and the tuberculous meningitis group were not statistically significant (P>0.05); no linear correlation existed between serum and cerebrospinal fluid PCT,but there was a linear relationship between the serum and the number of cells in cerebrospinal fluid. 【Conclusion】 The change of concentration of serum PCT can be used as an important diagnosis indicator of viral meningitis, purulent meningitis and tuberculous meningitis, and can also be used to guide the clinical treatment and estimate disease monitoring. But the medical value of cerebrospinal fluid PCT is not obvious. 2017 Vol. 34 (4): 682-685,687 [Abstract] ( 36 ) HTML (1 KB)  PDF  (0 KB)  ( 13 ) 685 Efficacy of Tacrolimus Combined with Glucocorticoid in Patients with Nephrotic Syndrome and its Effect on Inflammatory Factors TANG Jie DOI: 10.3969/j.issn.1671-7171.2017.04.019 【Objective】 To investigate the efficacy of tacrolimus combined with glucocorticoid in the treatment of nephrotic syndrome and the effect on the inflammatory factors. 【Methods】Eighty-six patients with nephrotic syndrome were randomly divided into the experimental group and the control group with 43 cases in each group. Both groups were treated with glucocorticoid, while the experimental group was additionally treated with tacrolimus. The blood lipids [triglyceride (TG), serum total cholesterol (TC), low- density lipoprotein (LDLC), high-density lipoprotein (HDLC)], inflammatory factors [interleukin -1 (IL-1), interleukin -6 (IL-6), tumor necrosis factor alpha (TNF-α)], renal function [blood urea nitrogen (BUN), serum creatinine (SCr), 24h urine protein quantitation] and adverse drug reactions were observed before and after treatment. 【Results】Before treatment, all showed no significant differences between the two groups (P>0.05); After treatment, TG, TC, LDLC, IL-1, IL-6, TNF-α, BUN, SCr and 24h urine protein quantitation decreased significantly while HDLC increased significantly; After treatment, TG, TC, LDLC, IL-1, IL-6, TNF-α, BUN, SCr, 24h urinary protein in the experimental group were significantly lower than those in the control group, HDLC increased significantly, and the difference was significant (P<0.05). There was no significant difference in the incidence of adverse drug reactions between the two groups (P>0.05).【Conclusion】 Tacrolimus combined with glucocorticoid in the treatment of nephrotic syndrome can significantly reduce the expression of inflammatory factors and improve the renal function of patients by effectively regulating the blood lipid levels. 2017 Vol. 34 (4): 685-687 [Abstract] ( 79 ) HTML (1 KB)  PDF  (0 KB)  ( 16 ) 688 Effect of Huachansu (Cinobufacini)Capsule Combined with Hepatic Arterial Infusion Chemoembolization in Patients with Liver Cancer YE Lu, YANG Li, MU Dan,et al DOI: 10.3969/j.issn.1671-7171.2017.04.020 【Objective】 To investigate the effect of cinobufacini capsules combined with hepatic arterial infusion chemoembolization in patients with liver cancer. 【Methods】Sixty-eight patients with hepatocellular carcinoma treated in our hospital were randomly divided into group A and group B, 34 cases in each. On the basis of TACE, the Group A was treated with the cinobufacini capsules, and the Group B underwent hepatic artery TACE only. The changes of plasma fibrinogen (FIB), tumor markers, clinical efficacy and quality of life were compared between the two groups before and after treatment.【Results】 There was no significant difference in FIB content between the two groups before treatment (P>0.05), and no significant difference existed in FIB content in the Group A before and after treatment (P>0.05) ; The FIB content in the group B was significantly higher than that before treatment, and was even significantly higher than that in the Group A (mean P<0.05). After treatment, the Cytokeratin 19 fragments, CEA, NSE concentrations of the two groups were significantly lower than those before treatment, and the difference was significant (P<0.05). It showed no significant difference between the three indexes of the Group A and the Group B after treatment (P>0.05).The disease control rate of the Group A was 77.5% (26/34), which was significantly higher than that of the Group B 67.6% (23/34); The incidence of pain and fatigue in the Group A was significantly lower than that in the Group B (P<0.05).【Conclusion】Cinobufacini capsules combined with TACE can improve the hypercoagulable state of blood in patients, which is beneficial for the treatment of cancer, improve the control rate of disease and improve the life quality of patients. 2017 Vol. 34 (4): 688-690,692 [Abstract] ( 79 ) HTML (1 KB)  PDF  (0 KB)  ( 15 ) 690 Comparison of the Anesthetic Effects between Simple Propofol and Propofol Combined with Fentanyl in Endoscopic Retrograde Cholangiopancreatography WANG Hui, CHENG Yong-jun, XU Shen DOI: 10.3969/j.issn.1671-7171.2017.04.021 【Objective】To compare the anesthetic effects between propofol and propofol combined with fentanyl in endoscopic retrograde cholangiopancreatography (ERCP). 【Methods】One hundred patients undergoing ERCP were randomized into two groups with 50 cases in each group. The observation group received propofol combined with fentanyl anesthesia while the control group received simple propofol anesthesia. The anesthetic effects were compared between the two groups. 【Results】The excellent rate of anesthesia in the observation group (96.00%) was significantly higher than that in the control group (76.00%) (P<0.05). There were no significant differences in the hemodynamics (HR, MAP, SpO2) of the observation group at different time points (P>0.05). On the other hand, the HR and MAP of the control group during the operation (at T2) were significantly lower than before the induction of anesthesia (at T0) (P<0.05). The extinction time of consciousness and time of consciousness recovery of the observation group were significantly shorter than those of the control group, and dosage of propofol was significantly less (P<0.05). The incidence of respiratory depression in the observation group (4.00%) was significantly lower than that in the control group (16.00%) (P<0.05) while there were no significant differences in hypotension and bradycardia (P>0.05). 【Conclusion】The anesthetic effect of propofol combined with fentanyl in ERCP was significantly better than that of propofol, and it can effectively maintain the stability of hemodynamics and reduce the dosage of propofol. 2017 Vol. 34 (4): 690-692 [Abstract] ( 63 ) HTML (1 KB)  PDF  (0 KB)  ( 14 ) 693 Effects of Concurrent Chemoradiotherapy and Sequential Radiotherapy and Chemotherapy on Progression-free Survival in Patients with Non-small Cell Lung Cancer BIE Zhi-xin, GUO Jun DOI: 10.3969/j.issn.1671-7171.2017.04.022 【Objective】To analyze the effect of concurrent chemoradiotherapy and sequential chemoradiotherapy on progression free survival in patients with limited Non-small-cell Carcinoma (NSCLC) induced by chemotherapy. 【Methods】One hundred and eight patients with NSCLC in our hospital were selected as the research object, the patients were randomly divided into group A and group B, each group with 54 cases. The group A received concurrent chemotherapy, the group B was treated with sequential chemotherapy. The adverse reaction rate, the therapeutic effect, the median survival after three cycles of treatment and quality of life score index were compared with between the two groups of patients.【Results】1.The curative effect of the group A was much higher than that of the group B (P<0.05); 2.The median progression free survival in group A was significantly higher than that in group B (P<0.05); 3.The incidence of adverse reactions in the group A was significantly lower than that in the group B (P<0.05); 4. Before treatment, there was no significant difference in quality of life between the two groups (P>0.05). After the treatment of the three cycle, the quality of life score of the group A was significantly higher than that of the group B (P<0.05).【Conclusion】Concurrent chemoradiotherapy can significantly improve the quality of life of patients with NSCLC, which has less adverse reactions and higher quality of life scores. 2017 Vol. 34 (4): 693-695 [Abstract] ( 54 ) HTML (1 KB)  PDF  (0 KB)  ( 14 ) 696 Clinical Efficacy and Side effects of Epirubicin, Oxaliplatin and Capecitabine in the Treatment of Advanced Gastric Cancer LIN Yan,DUAN Chun-yan, WANG Qiao-lin,et al DOI: 10.3969/j.issn.1671-7171.2017.04.023 【Objective】To investigate the clinical efficacy and side effects of epirubicin, oxaliplatin and capecitabine in the treatment of advanced gastric cancer.【Methods】Eighty cases of patients with gastric cancer treated in our hospital after first-line treatment with poor results and progressive disease were given with second-line treatment.The patients were divided into group A and group B according to the different methods of medication, the Group A was given epirubicin + oxaliplatin + capecitabine (mEXO) treatment, the group B was given irinotecan + 5- fluorouracil + leucovorin (FOLFIRI) treatment, the efficacy and toxicity of two groups were compared.【Results】The disease control rate was 42.5% (17/40) in the Group A, and that of the control group was 47.5%(19/40), there was no significant difference between the two groups (P>0.05); However, the incidence of blood toxicity, diarrhea and Ⅰ~Ⅱperipheral neurotoxicity in patients of the Group B were significantly higher than those in the Group A, and the difference was statistically significant (P<0.05).【Conclusion】If the they can withstand, patients with advanced gastric cancer may use epirubicin, oxaliplatin combined with capecitabine as second-line chemotherapy after the first-line chemotherapy proves to be ineffective. The effect is exact, the side effect is small, and is worthy of clinical treatment. 2017 Vol. 34 (4): 696-698,701 [Abstract] ( 59 ) HTML (1 KB)  PDF  (0 KB)  ( 15 ) 698 Effect of Insulin Resistance on Endocrine Metabolism and Ovarian Ultrasound Features in Patients with PCOS WANG Hai-yan, YU Zhan-feng DOI: 10.3969/j.issn.1671-7171.2017.04.024 【Objective】To investigate the effect of insulin resistance (IR) on endocrine metabolism and ovarian ultrasound features in patients with polycystic ovary syndrome (PCOS), and to analyze the relationships between the two. 【Methods】A total of 120 patients with PCOS were divided into IR - PCOS group (with IR,n=65) and NIR - PCOS group (without IR,n=55). The related indicators of endocrine metabolism [serum estradiol (E2), luteinizing hormone (LH), follicle stimulating hormone (FSH), total cholesterol (TC), fasting insulin (Fins)] were detected. The transvaginal ultrasound was performed to analyze related characteristic indexes [number of vesicles, ovarian volume (OV), number of follicles (NF)]. The correlation between endocrine metabolism and ovarian ultrasound indexes was analyzed. 【Results】Compared to the NIR - PCOS group, the levels of fasting plasma glucose (FPG), triglyceride (TG), Fins, TC, and LH in IR - PCOS group were significantly higher (P<0.05), while FSH level was significantly lower (P<0.05). There was no significant difference between two groups in terms of other endocrine metabolism indexes, such as E2 (P>0.05). The number of vesicles, NF, OV, and vascularization flow index (VFI) were significantly higher than those in the NIR- PCOS group (P<0.05), while there were no significant differences in ovarian stromal area (SA) or the ratio of ovarian stroma / total area (SA/TA) between the two groups (P>0.05). Correlation analysis showed that the number of vesicles, NF, and OV were positively correlated with PFG, Fins, TC, and LH (P<0.05) and negatively correlated with FSH (P<0.05). There was no correlation between other ultrasound characteristic indexes and other endocrine indexes in IR - PCOS group. 【Conclusion】IR can increase the risk of endocrine metabolic disorders in patients with PCOS and change the characteristics of ovarian ultrasound. The endocrine metabolism showed a certain correlation with ovarian ultrasound features in patients with IR-PCOS. 2017 Vol. 34 (4): 698-701 [Abstract] ( 39 ) HTML (1 KB)  PDF  (0 KB)  ( 12 ) 702 Influential Factors and Intervention Measures of Choosing Cesarean Section in Primipara DENG De-juan DOI: 10.3969/j.issn.1671-7171.2017.04.025 【Objective】To explore the factors influencing cesarean section in primipara and the intervention measures. 【Methods】The clinical data of 1280 primiparous women who were delivered in our hospital from January 2013 to December 2015 were analyzed. The incidence of cesarean section and related influential factors in the first three years were analyzed, and nursing interventions were established. 【Results】A total of 1,280 cases of primiparous women, 580 cases (45.31%) chose cesarean section. The rates of cesarean section in 2013, 2014 and 2015 were 31.17%, 42.35% and 59.57% respectively. The univariate analysis showed that the factors influencing the cesarean section of the primiparas included the age of the primipara, the BMI, the maternal education level, the husband's educational level, the family annual income, the medical insurance method, the complication of pregnancy, Childbirth education and past medical history. Multivariate Logisitc analysis showed that maternal age> 35 years, maternal BMI> 25 kg/m2, maternal education level junior high school or below, her husband education level junior high school or below, annual family income≥ 50,000 RMB and pregnancy complications were risk factors of the choice of cesarean section , while prenatal education of natural childbirth was the protective factor of cesarean section. 【Conclusion】In recent years, the rate of cesarean section is higher, and the factors influencing the cesarean section are related to the physical condition of the parturient, the education level of the mother and her husband, the family income and so on. Clinical practice should be combined with the actual situation of the nursing intervention. 2017 Vol. 34 (4): 702-704 [Abstract] ( 47 ) HTML (1 KB)  PDF  (0 KB)  ( 15 ) 705 Comparison of the Short-term Efficacy and Stress Reactions in Patients with Gastric Cancer Treated by Laparoscopic Surgery and Open Surgery WANG Jing-dong, ZHANG Tao, Adili,et al DOI: 10.3969/j.issn.1671-7171.2017.04.026 【Objective】 To compare the short-term efficacy and stress reactions in patients with gastric cancer treated by laparoscopic surgery and open surgery. 【Methods】The data of 128 patients with gastric cancer treated by D2 radical resection were retrospectively analyzed. They were divided into the laparoscopic group (A,n=68) and the open group (B,n=60) according to different surgical methods. The postoperative complications, short-term efficacy and stress reactions before surgery, 1 and 5days after surgery were compared between groups. 【Results】The number of dissected lymph nodes was (21.36±7.69), distance from the near end to tumor margin was (4.86±0.94) cm and the distance from the distal end to tumor margin was (4.32±0.76) cm, while those of the group B were (22.36±9.26)、(5.08±1.02)cm and (4.51±0.84)cm, respectively, the two groups showed no significant differences (P>0.05). One day after surgery, serum IL-6 and CRP levels increased significantly(P<0.05), and then decreased at d5 post operation(P<0.05), while IL-10 decreased at d1 after surgery(P<0.05)and then increased at d5 (P<0.05), and the changes of the group A were significantly lower than those of the group B (P<0.05).【Conclusion】 The effects of both laparoscopic surgery and open surgery are good in the treatment of gastric cancer but the former is more minimally invasive and patients can recover fast, and it has little effect on the stress reactions in patients as well. 2017 Vol. 34 (4): 705-707,710 [Abstract] ( 39 ) HTML (1 KB)  PDF  (0 KB)  ( 14 ) 707 Study on Preoperative SIADH after Cervical Spinal Cord Injury without Fracture and Dislocation QIU Min, FU Qin DOI: 10.3969/j.issn.1671-7171.2017.04.027 【Objective】To investigate the outcomes of surgery in patients' treatments who have syndrome of inappropriate secretion of antidiuretic (SIADH) after cervical spinal cord injury without fracture and dislocation. 【Methods】Twenty-six patients with cervical spinal cord injury without fracture and dislocation who received surgery in our department from September 2010 to September 2014 were retrospectively analyzed. Frankel classification and Japanese Orthopedic Association (JOA) scores were recorded to estimate the level of spinal cord injury. Before surgery, Frankel grade A had 12 cases and grade B had 14 cases. All patients underwent spinal decompression surgery. The time of SIADH after injury, serum sodium, urine sodium, plasma osmotic pressure, urine osmotic pressure and final result were summarized and analyzed. 【Results】 All twenty-six patient were followed up between twelve and thirty-seven months, average twenty-six months. In the last follow-up, eight cases belonged to Frankel classification grade A and eighteen cases belonged to grade B (or below B). JOA score was 11.6±3.1 in the last follow-up and the rate of improvement was 78.2%. The time of SIADH was 4~10 days after injury and time of recovery was 28.4±13.8 days. 【Conclusion】 The spinal decompression surgery was safe and reliable for the patients with cervical spinal cord injury without fracture and dislocation, however, special attention should be paid to SIADH during the perioperative period. Early diagnosis and early treatment (sodium intake and fluid infusion restriction) can lead to effective treatment of SIADH. 2017 Vol. 34 (4): 707-710 [Abstract] ( 52 ) HTML (1 KB)  PDF  (0 KB)  ( 16 ) 711 Curative Effect of Laparoscope in Treating Endometriosis Combined with Infertility and Factors Affecting Pregnancy after Operation LIANG Xiu-wen, JI Xin-mei DOI: 10.3969/j.issn.1671-7171.2017.04.028 【Objective】To investigate the curative effect of laparoscope in treating endometriosis combined with infertility and factors affecting pregnancy after the operation. 【Methods】A total of 70 patients who received laparoscopic operation in the treatment of ovarian endometriosis complicated with infertility were selected as the observation group and sixty cases of endometriosis with infertility who received conservative abdomen-open surgery were recruited as the control group. Clinical data, outcomes of surgery, and factors affecting the postoperative pregnancy of the two groups were analyzed. 【Results】The durations of the operation and the first postoperative exsufflation of the observation group were shorter than those of the control group, with statistically significant difference (P<0.05). Postoperative complications of the two groups were not statistically significant different (P>0.05). During the 2 years of follow-up after surgery, the pregnancy rate of the observation group was higher than that of the control group (P<0.05). Univariate analysis showed that postoperative pregnancy rate of the observation group was closely related to factors including the R-AFS staging, postoperative tubal patency, postoperative combined medication and treatment for assisting pregnancy. Multivariate stepwise logistic regression results showed that treatment for assisting pregnancy, postoperative combined medication and tubal patency after the surgery were independent factors affecting postoperative pregnancy of patients with ovarian endometriosis complicated with infertility who were treated by laparoscopic operation. 【Conclusion】 Laparoscopic surgery for endometriosis complicated with infertility has advantages of less injury and rapid recovery. To effectively improve the patient's postoperative pregnancy rate, it is of great significance to ensure tubal patency, timely combination of medication and other appropriate ways to boost the pregnancy. 2017 Vol. 34 (4): 711-714 [Abstract] ( 42 ) HTML (1 KB)  PDF  (0 KB)  ( 15 ) 714 Influence of Blood Glucose Monitoring on the Prognosis of Esophageal Cancer Surgery in Elderly Patients with High Blood Glucose HUANG Chang-ru, HUANG Ji-ju, WANG Xiao-bin DOI: 10.3969/j.issn.1671-7171.2017.04.029 【Objective】To explore the clinical effect of blood glucose monitoring on the prognosis of elderly patients that have undergone esophageal cancer operation. 【Methods】A total of eighty-two patients with esophageal cancer surgery in elderly patients with high blood glucose from June 2011 to June 2016 in our hospital were recruited as the research subject. They were randomly divided into the observation group and the control group, with 41 cases in each. Patients in the observation group received blood glucose monitoring and management to put blood glucose under control, while patients in the control group only received routine management. Blood glucose, white blood cell, C reactive protein (CRP), incision drainage and anastomotic leakage, complications, and mortality were recorded. 【Results】The incidence of postoperative complications was 14.63% (6/41) in the observation group, which was significantly lower than that in the control group (63.41%, 26/41). There were no deaths in the observation group and 2 cases of death in the control group. The incisional drainage of the observation group was better than that of the control group. The levels of blood glucose, CRP and white blood cells in the observation group were lower than those in the observation group; the difference was statistically significant (P<0.05).【Conclusion】Monitoring of blood glucose has a significant impact on the prognosis of elderly esophageal cancer patients with high blood glucose level. It can significantly reduce the incidence of complications and deaths in elderly patients with hyperglycemia. 2017 Vol. 34 (4): 714-716 [Abstract] ( 51 ) HTML (1 KB)  PDF  (0 KB)  ( 15 ) 717 Effect of Self-Efficacy Nursing Management on Clinical Symptoms and Quality of Life in Aged Patients with Peptic Ulcer YAN Yun-xia DOI: 10.3969/j.issn.1671-7171.2017.04.030 【Objective】To investigate the effect of self-efficacy nursing interventions on clinical symptoms and quality of life in elderly patients with peptic ulcer.【Methods】A total of 120 cases of elderly patients with peptic ulcer from January 2015 to December 2015 were divided into the observation group (n=60) and the control group (n=60). Patients in the control group were given with routine clinical nursing care alone, while the observation group patients were given additional self-efficacy management with routine nursing care. Clinical symptoms, changes in self-efficacy, and quality of life were compared between the two groups before and after intervention. 【Results】The abdominal pain, belching, acid reflux, bloating and other clinical symptom scores of the observation group were lower than those of the control group (P<0.05). The level of self-efficacy score of the observation group was higher than that of the control group (P<0.05). The overall score of life quality and scores in different dimensions (social, psychology, physiology, environment) were higher in the observation group than in the control groups (P<0.05). 【Conclusion】Self-efficacy nursing interventions can effectively improve clinical symptoms of elderly patients with peptic ulcer and increase life quality as well. 2017 Vol. 34 (4): 717-719 [Abstract] ( 38 ) HTML (1 KB)  PDF  (0 KB)  ( 15 )

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