手术治疗无骨折脱位颈脊髓损伤合并抗利尿激素分泌失调综合征的疗效观察

doi:10.3969/j.issn.1671-7171.2017.04.027

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Abstract 【Objective】To investigate the outcomes of surgery in patients' treatments who have syndrome of inappropriate secretion of antidiuretic (SIADH) after cervical spinal cord injury without fracture and dislocation. 【Methods】Twenty-six patients with cervical spinal cord injury without fracture and dislocation who received surgery in our department from September 2010 to September 2014 were retrospectively analyzed. Frankel classification and Japanese Orthopedic Association (JOA) scores were recorded to estimate the level of spinal cord injury. Before surgery, Frankel grade A had 12 cases and grade B had 14 cases. All patients underwent spinal decompression surgery. The time of SIADH after injury, serum sodium, urine sodium, plasma osmotic pressure, urine osmotic pressure and final result were summarized and analyzed. 【Results】 All twenty-six patient were followed up between twelve and thirty-seven months, average twenty-six months. In the last follow-up, eight cases belonged to Frankel classification grade A and eighteen cases belonged to grade B (or below B). JOA score was 11.6±3.1 in the last follow-up and the rate of improvement was 78.2%. The time of SIADH was 4~10 days after injury and time of recovery was 28.4±13.8 days. 【Conclusion】 The spinal decompression surgery was safe and reliable for the patients with cervical spinal cord injury without fracture and dislocation, however, special attention should be paid to SIADH during the perioperative period. Early diagnosis and early treatment (sodium intake and fluid infusion restriction) can lead to effective treatment of SIADH.

Key words： Spinal Cord Injuries/CO Spinal Cord Injuries/SU Inappropriate ADH Syndrome/CO Inappropriate ADH Syndrome/SU Dislocations

Received: 30 October 2015

PACS:

R651.21

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	QIU Min
	FU Qin

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QIU Min,FU Qin. Study on Preoperative SIADH after Cervical Spinal Cord Injury without Fracture and Dislocation[J]. JOURNAL OF CLINICAL RESEARCH, 2017, 34(4): 707-710.

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http://www.jcr.net.cn/EN/10.3969/j.issn.1671-7171.2017.04.027 OR http://www.jcr.net.cn/EN/Y2017/V34/I4/707

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(本文编辑:邓丽萍) [收稿日期] 2015-10-30

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