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| Curative Effect of Laparoscope in Treating Endometriosis Combined with Infertility and Factors Affecting Pregnancy after Operation |
| LIANG Xiu-wen, JI Xin-mei |
| Department of Gynecology, People's Hospital of Longhua New District, Shenzhen 518109, China |
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Abstract 【Objective】To investigate the curative effect of laparoscope in treating endometriosis combined with infertility and factors affecting pregnancy after the operation. 【Methods】A total of 70 patients who received laparoscopic operation in the treatment of ovarian endometriosis complicated with infertility were selected as the observation group and sixty cases of endometriosis with infertility who received conservative abdomen-open surgery were recruited as the control group. Clinical data, outcomes of surgery, and factors affecting the postoperative pregnancy of the two groups were analyzed. 【Results】The durations of the operation and the first postoperative exsufflation of the observation group were shorter than those of the control group, with statistically significant difference (P<0.05). Postoperative complications of the two groups were not statistically significant different (P>0.05). During the 2 years of follow-up after surgery, the pregnancy rate of the observation group was higher than that of the control group (P<0.05). Univariate analysis showed that postoperative pregnancy rate of the observation group was closely related to factors including the R-AFS staging, postoperative tubal patency, postoperative combined medication and treatment for assisting pregnancy. Multivariate stepwise logistic regression results showed that treatment for assisting pregnancy, postoperative combined medication and tubal patency after the surgery were independent factors affecting postoperative pregnancy of patients with ovarian endometriosis complicated with infertility who were treated by laparoscopic operation. 【Conclusion】 Laparoscopic surgery for endometriosis complicated with infertility has advantages of less injury and rapid recovery. To effectively improve the patient's postoperative pregnancy rate, it is of great significance to ensure tubal patency, timely combination of medication and other appropriate ways to boost the pregnancy.
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[1] 王珺. 影响子宫内膜异位症不孕患者腹腔镜手术后妊娠率的多因素分析[J].中国微创外科杂志, 2012, 12(2): 108-111.
[2] 赵文龙, 张信美. 促性腺激素释放激素激动剂治疗腹腔镜下保守手术后中重度子宫内膜异位症效果观察[J].中国现代医生, 2014, 52(13):68-70.
[3] 俞丹华. 巨噬细胞移动抑制因子、血管生成素-2、血管内皮生长因子在子宫内膜异位症中的意义[J].临床和实验医学杂志, 2015(2):101-103.
[4] 比丽克孜·艾克木, 克比努尔·艾则孜. 宫腹腔镜联合药物治疗子宫内膜异位症并不孕症的疗效及相关影响因素分析[J].实用临床医学, 2013, 14(6):76-77.
[5] 毛邱娴. 不同术式治疗深部浸润性肠道子宫内膜异位症的临床疗效[J].中国生育健康杂志, 2015, 26(2): 152-153.
[6] Zhou J, Chaudhry H, Zhong Y,et al. Dysregulation in microRNA expression in peripheral blood mononuclear cells of sepsis patients is associated with immunopathology.[J]. Cytokine,2015, 71(1):89-100.
[7] 李焱, 张震宇, 刘崇东. 子宫内膜异位症合并不孕患者腹腔镜术后药物治疗妊娠结局分析[J].实用妇产科杂志, 2015, 31(1): 53-56.
[8] 武玉莲. 宫腹腔镜联合治疗输卵管阻塞不孕症50例临床研究[J].中国临床医生杂志, 2015, 43(1):76-78.
[9] 李明远. 宫腔镜下输卵管插管通液术治疗不孕不育患者的临床疗效[J].中国实用医药, 2015, 10(22):199-200.
[10] 黄静莹. 分析腹腔镜保守手术对输卵管妊娠并存输卵管病变患者术后生育能力产生的影响[J].中国实用医药, 2015, 10(10):106-108.
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2017, Vol. 34 
