胃癌腹腔镜手术与开腹手术近期疗效及机体应激性反应比较

doi:10.3969/j.issn.1671-7171.2017.04.026

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Abstract 【Objective】 To compare the short-term efficacy and stress reactions in patients with gastric cancer treated by laparoscopic surgery and open surgery. 【Methods】The data of 128 patients with gastric cancer treated by D₂ radical resection were retrospectively analyzed. They were divided into the laparoscopic group (A,n=68) and the open group (B,n=60) according to different surgical methods. The postoperative complications, short-term efficacy and stress reactions before surgery, 1 and 5days after surgery were compared between groups. 【Results】The number of dissected lymph nodes was (21.36±7.69), distance from the near end to tumor margin was (4.86±0.94) cm and the distance from the distal end to tumor margin was (4.32±0.76) cm, while those of the group B were (22.36±9.26)、(5.08±1.02)cm and (4.51±0.84)cm, respectively, the two groups showed no significant differences (P>0.05). One day after surgery, serum IL-6 and CRP levels increased significantly(P<0.05), and then decreased at d5 post operation(P<0.05), while IL-10 decreased at d₁ after surgery(P<0.05)and then increased at d₅ (P<0.05), and the changes of the group A were significantly lower than those of the group B (P<0.05).【Conclusion】 The effects of both laparoscopic surgery and open surgery are good in the treatment of gastric cancer but the former is more minimally invasive and patients can recover fast, and it has little effect on the stress reactions in patients as well.

Key words： Stomach Neoplasms/SU Laparoscopy Treatment Outcome Stress

Received: 07 December 2016

PACS:

R735.2

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http://www.jcr.net.cn/EN/10.3969/j.issn.1671-7171.2017.04.026 OR http://www.jcr.net.cn/EN/Y2017/V34/I4/705