|
|
|
| Correlation between Heart Rate Variability , Blood Pressure Variability and Vascular Injury in Patients with Essential Hypertension |
| LIAO Die, ZHOU Hua |
| Department of Cardiovascular and Cerebrovascular, Hospital of Traditional Chinese Medicine Lehan, Sichuan 614000, China |
|
|
|
Abstract 【Objective】 To investigate the correlation between heart rate variability, blood pressure variability and vascular injury in patients with essential hypertension.【Methods】The clinical data of 405 patients with essential hypertension admitted to our hospital from June 2013 to June 2016 were retrospectively analyzed. According to their brachial ankle pulse wave velocity (baPWV), the patients were divided into baPWV normal group (baPWV < 14 m/s,n=267) and baPWV raising group (baPWV=14 m/s,n=138). All patients were monitored with 24 h dynamic electrocardiogram, and the heart rate variability was analyzed using time domain and frequency domain analysis; Ambulatory blood pressure was monitored in all the patients, and the heart rate variability and blood pressure variability were compared between the two groups to analyze the correlation with vascular injury.【Results】The standard deviation (SDANN) of the mean value of RR interval of every 5 min in patients thebaPWV normal group was higher than that in the baPWV raising group; Low frequency (LF), high frequency (HF), low frequency / high frequency (LF/HF), night / day heart rate (nHR/dHR) was lower than that of the baPWV raising group, the difference was statistically significant (P<0.05).24 h average pulse pressure (24hPP), 24 h mean systolic blood pressure (24hSBP), daytime average systolic blood pressure (dSBP), the mean pressure (dPP), nocturnal mean systolic blood pressure (nSBP), 24 h systolic blood pressure standard deviation (24hSSD) of the BaPWV normal group were lower than those of the baPWV raising group, the rate of nocturnal systolic blood pressure (SBPF) was higher than that of the baPWV raising group, the difference was statistically significant (P<0.05). LF, LF/HF, nHR/dHR, 24hPP and 24hSSD showed significant positive correlation with baPWV (P<0.05). 【Conclusion】LF, LF/HF, nHR/dHR, 24hPP and 24hSSD are significantly positively correlated with baPWV in patients with essential hypertension, which means that heart rate variability and blood pressure variability are significantly correlated with vascular injury in patients with essential hypertension.
|
|
Received: 07 July 2016
|
|
|
|
|
|
[1] Tocci G, Cicero AF, Salvetti M,et al. Attitudes and preferences for the clinical management of hypertension and hypertension-related cardiac disease in general practice: results of the Italian Hypertension and Heart Survey[J].J Human Hypertension,2015,29(7):409-416.
[2] Sherstnev VV,Gruden MA, Elistratova EI,et al. Molecular markers of arterial hypertension in patients with normotony, pre-hypertension and hypertension[J].Bulletin Experimental Biol Med,2015,158(5):604-606.
[3] 张永红,赵仁华,薛元明,等.2型糖尿病合并高血压对自主及周围神经病变的影响研究[J].中国全科医学,2013,16(7):752-754.
[4] 王宁,刘傲亚,余振球,等.高血压患者同型半胱氨酸与脉搏波传导速度关系的研究[J].心肺血管病杂志,2016,35(4):282-284.
[5] 郭琳,聂连涛,李中健,等.高血压前期与自主神经功能改变关系分析[J].中国全科医学,2014,17(34):4087-4089.
[6] 赵刚,李四海,谭熙,等.原发性高血压患者自主神经功能与动脉硬化的相关性[J].中华心血管病杂志,2016,44(3):226-230.
[7] 郭大英,戴肖松,姚艳.左心室肥厚与心率变异性及室性心律失常的相关性[J].医学临床研究,2009,26(10):1931-1933.
[8] 吴俊兰,周璇,马斌武,等.老年高血压患者动态血压与脉搏波传导速度的相关性[J].中国老年学杂志,2015,17(5):1218-1220.
[9] 王伟,刘红军,赵春丽,等.正常体质量中青年轻中度高血压人群脉搏波传导速度变化[J].中国基层医药,2015,11(11):1620-1622.
[10] 陈炳伟,王志广,党爱民,等.颈-股脉搏波速度与冠状动脉病变严重程度关系的研究[J].中国循环杂志,2015,30(4):326-330.
[11] Chen HF, Chang-Quan H, You C, et al.The circadian rhythm of arterial blood pressure in Alzheimer disease (AD) patients without hypertension[J].Blood Press,2013,22(2):101-105.
[12] 侯艳杰,李娜.心率变异性在冠心病患者和冠心病合并高血压患者中应用价值的比较[J].临床和实验医学杂志,2016,15(4):325-327.
[13] 徐燕,王梦琳,高旭光,等.原发性高血压患者血压变异性和颈动脉粥样硬化的相关性研究[J].中国全科医学,2013,16(11):1206-1209.
[14] 沈安娜,郑德仲,胡兆霆,等.原发性高血压患者昼夜节律与自主神经功能及心肌能量消耗的相关性[J].南方医科大学学报,2014,34(5):713-717.
(本文编辑:张兴珍) [收稿日期] 2016-07-07
|
|
|
|
2017, Vol. 34 
