医学临床研究
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2026 Vol. 43, No. 9
Published: 2026-09-26
Original Articles
Original Articles
1409
Application Effect of Intervention Based on Kano Model in Patients with Diabetic Retinopathy
XU Lu,WU Chenchan,XIAO Qiong,LIU Xin
DOI: 10.3969/j.issn.1671-7171.2026.09.001
【Objective】To explore the application effect of an intervention based on the Kano model in patients with diabetic retinopathy (DR). 【Methods】A total of 120 patients with DR admitted to the First People's Hospital of Hangzhou from June 2022 to June 2025 were selected and divided into a control group and an observation group by the envelope drawing method, with 60 cases in each group. The control group received routine intervention, and the observation group received an intervention based on the Kano model. The improvement of visual function, negative emotions, and quality of life were compared between the two groups. 【Results】After the intervention, the scores of all dimensions of the visual function scale in the observation group were lower than those in the control group (P<0.05); the Hamilton Anxiety Scale (HAMA) score and the Hamilton Depression Scale (HAMD) score in the observation group were lower than those in the control group (all P<0.05); and the scores of all dimensions of the 36-Item Short Form Health Survey (SF-36) in the observation group were higher than those in the control group (all P<0.05). 【Conclusion】The intervention based on the Kano model applied to patients with DR can significantly improve their visual function, alleviate negative emotions, and enhance their quality of life, and is worthy of clinical promotion and application.
2026 Vol. 43 (9): 1409-1411 [
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1412
Clinical Efficacy of Continuous Renal Replacement Therapy Combined with Hemoperfusion in the Treatment of Sepsis
XIN Shuzhen,HU Xiaohuaa,LIU Xiaoying,DING Chaob
DOI: 10.3969/j.issn.1671-7171.2026.09.002
【Objective】 To investigate the clinical efficacy of continuous renal replacement therapy (CRRT) combined with hemoperfusion in patients with sepsis. 【Methods】A total of 80 patients with sepsis admitted to Binzhou People's Hospital from May 2023 to August 2025 were randomly assigned to the control group (treated with CRRT alone) and the observation group (treated with CRRT combined with hemoperfusion), with 40 patients in each group. The recovery time, tissue perfusion indicators, inflammatory factors, T lymphocyte subsets, health status, and mortality rate were compared between the two groups. 【Results】 Compared with the control group, the duration of mechanical ventilation and length of ICU stay were shorter in the observation group (all P<0.05). After treatment, the mean arterial pressure (MAP) was higher, and lactate level was lower in the observation group than those in the control group (all P<0.05). The levels of inflammatory factors in the observation group were lower than those in the control group (all P<0.05). The observation group exhibited higher total lymphocyte count (LYM), Th cells, and CD4
+
/CD8
+
ratios compared to the control group (all P<0.05). The acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ) score in the observation group was lower than that in the control group (P<0.05). There was no statistically significant difference in 28-day mortality between the two groups (P>0.05). 【Conclusion】 CRRT combined with hemoperfusion can effectively shorten recovery time, improve immune function, inflammatory factor levels, and health status in patients with sepsis, providing an effective therapeutic strategy for sepsis management.
2026 Vol. 43 (9): 1412-1415 [
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1416
Diagnostic Value of High-Frequency Ultrasound for Intussusception Secondary to Juvenile Polyps
TAN Bixing,HU Yuan,TANG Yiqian,LIU Jinqiao
DOI: 10.3969/j.issn.1671-7171.2026.09.003
【Objective】To explore the diagnostic value of high-frequency ultrasound for intussusception secondary to juvenile polyps. 【Methods】 The clinical data of 66 children with pathologically-confirmed intussusception secondary to juvenile polyps admitted to Children's Hospital Affiliated to Xiangya Medical School, Central South University (Hunan Provincial Children's Hospital) from January 2020 to December 2025 were collected, and the diagnostic value of high-frequency ultrasound for this disease was analyzed. 【Results】 A total of 66 cases with 67 juvenile polyps were detected by high-frequency ultrasound, including 65 cases of single polyp (65 polyps) and 1 case of multiple polyps (2 polyps). A total of 71 juvenile polyps were confirmed by surgery and colonoscopy: 62 cases of single polyp (62 polyps) and 4 cases of multiple polyps (3 cases with 2 polyps, 1 case with 3 polyps). The detection rate of high-frequency ultrasound for juvenile polyps was 94.37% (67/71). The sonographic features of intussusception secondary to juvenile polyps were as follows: typical "target-ring sign" could be seen on short-axis section, with a solid, heterogeneous hypoechoic mass located in the center or on one side of the intestinal lumen; "sleeve sign" was observed on long-axis section. The hypoechoic mass was mostly oval or quasi-circular, connected to the intestinal wall on one side through a pedicle-like hypoechoic structure. Color Doppler flow imaging revealed abundant blood-flow signals within the hypoechoic mass, with blood flow entering the mass from the intestinal wall through the slender pedicle-like structure. 【Conclusion】 High-frequency ultrasound can clearly display the number, size and blood supply of polyps in children with intussusception secondary to juvenile polyps. It can also accurately locate the specific intestinal segment and involved scope of intussusception. It can be used as the preferred imaging modality for clinical diagnosis of intussusception secondary to juvenile polyps.
2026 Vol. 43 (9): 1416-1418 [
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1419
Effects of a Health Education Program Based on Goal Attainment Theory on Psychological Status and Cardiac Function in Patients with Acute Myocardial Infarction after Percutaneous Coronary Intervention
WEI Yanan,HAN Yu
DOI: 10.3969/j.issn.1671-7171.2026.09.004
【Objective】To investigate the effects of a health education program based on goal attainment theory on the psychological status and cardiac function of patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI). 【Methods】A total of 80 patients with AMI admitted to the First Affiliated Hospital of Henan University of Science and Technology from January 2024 to June 2025 were selected and divided into a control group (receiving routine nursing intervention) and an observation group (receiving a health education program based on goal attainment theory) using a random number table method, with 40 cases in each group. Before the intervention and 6 months after the intervention, cardiac function indicators [left ventricular ejection fraction (LVEF), left ventricular end-diastolic dimension (LVEDD)], exercise tolerance [maximum distance of the 6-minute walk test (six-minute walk distance, 6MWD)], psychological status [Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS) scores], and the incidence of major adverse cardiovascular events were compared between the two groups. 【Results】Six months after the intervention, the SAS and SDS scores of both groups were lower than those before the intervention, and the above scores in the observation group were lower than those in the control group, with statistically significant differences (all P<0.05). The LVEF and 6MWD of both groups were greater than those before the intervention, and the LVEDD of both groups was lower than that before the intervention; moreover, the LVEF and 6MWD in the observation group were greater than those in the control group, and the LVEDD in the observation group was lower than that in the control group, with statistically significant differences (all P<0.05). The incidence of major adverse cardiovascular events was 7.50% (3/40) in the observation group and 20.00% (8/40) in the control group, with no statistically significant difference between the two groups (χ
2
=2.635, P=0.105). 【Conclusion】The health education program based on goal attainment theory can alleviate the anxiety and depression of AMI patients after PCI, improve their cardiac function, and enhance their exercise tolerance.
2026 Vol. 43 (9): 1419-1422 [
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1423
Predictive Value of Lung Ultrasound Scoring for Poor Prognosis in Neonatal Respiratory Distress Syndrome
GUO Fengjuan,LIANG Guosheng,BIAN Fubao,GE Jianli,ZHANG Zhiling,LI Kaizhen
DOI: 10.3969/j.issn.1671-7171.2026.09.005
【Objective】To investigate the predictive value of lung ultrasound scoring (LUS) for poor prognosis in neonatal respiratory distress syndrome (NRDS). 【Methods】A total of 50 neonates with neonatal respiratory distress syndrome admitted to Puyang Oilfield General Hospital from January 2022 to October 2025 were enrolled. According to the prognosis after 7 days of treatment, the patients were divided into the good prognosis group (n=34) and the poor prognosis group (n=16). General data were compared between the two groups. Spearman rank correlation analysis was used to evaluate the correlations of LUS with blood routine parameters, blood gas analysis parameters, and clinical grading. Receiver operating characteristic (ROC) curve analysis was used to evaluate the predictive value of LUS for poor prognosis in NRDS after 7 days of treatment. 【Results】LUS was negatively correlated with white blood cell count (P<0.05), but showed no correlation with neutrophil percentage, lymphocyte percentage, pre-treatment pH, arterial partial pressure of oxygen (PaO
2
), or clinical grading (all P>0.05). Among the 50 neonates, 34 had a good prognosis (the good prognosis group) and 16 had a poor prognosis (the poor prognosis group). There were statistically significant differences between the two groups regarding body length, body weight, whether ventilator use duration ≥7 days, LUS, and oxygenation index (all P<0.05). There were no statistically significant differences between the two groups in terms of 1-minute Apgar score, white blood cell count, neutrophil percentage, lymphocyte percentage, CRP, pre-treatment pH, or PaO
2
(all P>0.05). The area under the ROC curve of LUS for predicting poor prognosis in NRDS after 7 days of treatment was 0.692, with a sensitivity of 27.00% and a specificity of 71.00%. 【Conclusion】LUS shows no significant correlation with clinical grading in neonatal respiratory distress syndrome, but it has important clinical value in predicting poor prognosis in neonatal respiratory distress syndrome.
2026 Vol. 43 (9): 1423-1426 [
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1427
Comparison of Multislice Spiral CT Features in Patients with Different Pathological Subtypes of Primary Lung Adenocarcinoma
ZHANG Wenyan,SONG Zhenyu
DOI: 10.3969/j.issn.1671-7171.2026.09.006
【Objective】To compare the multislice spiral computed tomography (MSCT) features of patients with different pathological subtypes of primary lung adenocarcinoma. 【Methods】The clinical data of 103 patients with primary lung adenocarcinoma who were diagnosed and treated at Zhengzhou People's Hospital from January 2021 to June 2023 were retrospectively analyzed. All patients underwent chest CT scanning and were classified, according to the classification criteria of lung adenocarcinoma, into adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), and invasive adenocarcinoma (IAC). Relevant clinical data and MSCT features were compared among the three groups. 【Results】 Among the 103 patients with primary lung adenocarcinoma, 54 (52.43%) were in the AIS group, 27 (26.21%) in the MIA group, and 22 (21.36%) in the IAC group. There were no significant differences among the three groups in aspect of age, sex, or lesion location (all P>0.05). The lymph node metastasis rates in the MIA and IAC groups were 33.33% (9/27) and 86.36% (19/22), respectively, which were both higher than that in the AIS group (all P<0.05); And the lymph node metastasis rate in the IAC group was higher than that in the MIA group (P<0.05). The postoperative recurrence rates in the MIA and IAC groups were 22.22%(6/27) and 36.36%(8/22), respectively, both higher than that in the AIS group (all P<0.05); however, there was no significant difference between the MIA and IAC groups (P>0.05). The incidences of spiculation, lobulation, and vascular convergence in the IAC group were higher than those in the AIS and MIA groups (all P<0.05). There were no significant differences among the three groups in the incidences of air bronchogram and pleural indentation (all P>0.05). The mean nodule diameter and mean CT attenuation value showed a gradual increasing trend across the AIS, MIA, and IAC groups, with significant differences between each pair of groups (all P<0.05). 【Conclusion】 Patients with different pathological subtypes of primary lung adenocarcinoma exhibit significant differences in MSCT features. Understanding these characteristic imaging findings may provide clinical value for the diagnosis and treatment of patients with primary lung adenocarcinoma.
2026 Vol. 43 (9): 1427-1430 [
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1431
Application Effect of Phased-Detailed Nursing in Patients Undergoing Laparoscopic Surgery for Uterine Fibroids
WANG Jinga,LI Yukeb,ZHANG Yanlia
DOI: 10.3969/j.issn.1671-7171.2026.09.007
【Objective】 To explore the application effect of phased-detailed nursing in patients undergoing laparoscopic surgery for uterine fibroids.【Methods】 A total of 90 patients who received laparoscopic surgery for uterine fibroids in Luoyang Maternal and Child Health Hospital from May 2023 to April 2024 were selected. Patients were grouped by ball-drawing method; odd-numbered patients were assigned to the control group (receiving routine nursing), and even-numbered patients to the observation group (receiving phased-detailed nursing on the basis of routine nursing), with 45 cases in each group. The postoperative recovery, pelvic floor muscle function, quality of life [Generic Quality of Life Inventory-74 (GQOLI-74) score], and negative emotions [Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS) scores] were compared between the two groups.【Results】 After intervention, the time to get out of bed, hospital stay and gastrointestinal peristalsis recovery time in the observation group were significantly shorter than those in the control group (all P<0.05). The pelvic floor muscle strength score of the observation group was higher, while each dimension score of ICIQ-UISF was lower than those of the control group (all P<0.05). After intervention, each-dimension scores and total score of GQOLI-74 in both groups were higher than those before intervention, and the observation group achieved higher scores than the control group (all P<0.05). The SAS and SDS scores of both groups decreased after intervention, and the scores in the observation group were lower than those in the control group (all P<0.05).【Conclusion】For patients undergoing laparoscopic surgery for uterine fibroids, phased-detailed nursing can promote the recovery of physiological function and pelvic floor muscle function, improve quality of life and relieve anxiety and depression, which is worthy of further clinical promotion.
2026 Vol. 43 (9): 1431-1434 [
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1435
Effects of Family-Style Ward Combined with Doctor-Nurse Collaboration Model on Anxiety Severity and Quality of Life in Patients with Hepatocellular Carcinoma
XU Jifang,XU Fuguo
DOI: 10.3969/j.issn.1671-7171.2026.09.008
【Objective】To explore the effects of a family-style ward combined with doctor-nurse collaboration model on the anxiety severity and quality of life of patients with hepatocellular carcinoma (HCC).【Methods】A total of 87 patients with HCC admitted to Luoyang Fifth People's Hospital from June 2024 to December 2025 were selected and divided into a control group (receiving doctor-nurse collaboration model intervention on the basis of routine nursing care, n=43) and an observation group (additionally receiving family-style ward nursing intervention on the basis of the control group, n=44) using a random number table method. The severity of psychological anxiety [Self-Rating Anxiety Scale (SAS), Generalized Anxiety Disorder-7 (GAD-7), and Hamilton Anxiety Rating Scale (HAMA) scores], pain degree [Short-Form McGill Pain Questionnaire (SF-MPQ) scores], and quality of life [European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) scores] were compared between the two groups.【Results】After the intervention, the SAS, GAD-7, and HAMA scores of both groups were lower than those before the intervention, and the above scores in the observation group were lower than those in the control group, with statistically significant differences (all P<0.05). After the intervention, the Pain Rating Index (PRI), Visual Analogue Scale (VAS), and Present Pain Intensity (PPI) scores of both groups were lower than those before the intervention, and the above scores in the observation group were lower than those in the control group, with statistically significant differences (all P<0.05). After the intervention, the physical functioning, role functioning, emotional functioning, cognitive functioning, and social functioning scores of both groups were higher than those before the intervention, while the fatigue, nausea, and pain scores were lower than those before the intervention; moreover, the physical functioning, role functioning, emotional functioning, cognitive functioning, and social functioning scores in the observation group were higher than those in the control group, while the fatigue, nausea, and pain scores were lower than those in the control group, with statistically significant differences (all P<0.05).【Conclusion】The family-style ward combined with doctor-nurse collaboration model can significantly alleviate the anxiety severity and pain degree of patients with HCC and improve their quality of life.
2026 Vol. 43 (9): 1435-1438 [
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1439
Effects of Absorbable Screw Internal Fixation versus Compression Cannulated Screw Internal Fixation in the Treatment of Ankle Fracture Patients
LI Zhiqiang,CHEN Kunfeng,DONG Hui,WANG Hongqi
DOI: 10.3969/j.issn.1671-7171.2026.09.009
【Objective】 To investigate the clinical effects of absorbable screw internal fixation and compression cannulated screw internal fixation for patients with ankle fractures.【Methods】 The clinical data of 76 patients with ankle fractures treated in the Department of Emergency Trauma Surgery of First People's Hospital of Shangqiu City from October 2017 to October 2023 were retrospectively analyzed. According to different surgical procedures, the patients were divided into the control group (treated with compression cannulated screw internal fixation) and the observation group (treated with absorbable screw internal fixation), with 38 cases in each group. Operation-related indicators, ankle function scores, pain scores, functional prognosis and complication rates were compared between the two groups.【Results】 The callus formation time (31.25±5.43)d and fracture healing time (105.84±10.39) d in the observation group were significantly shorter than those in the control group [(36.27±5.52) d, (118.51±10.54) d](all P<0.05). At 3 months after operation, the ankle function score of the observation group (73.51±4.38) was significantly higher than that of the control group (69.42±4.47); the pain score (3.57±0.55) was significantly lower than that of the control group (4.12±0.57), and the functional prognosis was better in the observation group (all P<0.05). There was no statistically significant difference in the total incidence of complications between the two groups (P>0.05).【Conclusion】 For patients with ankle fractures, absorbable screw internal fixation can promote fracture healing, relieve early postoperative pain and improve early functional prognosis, with comparable safety to compression cannulated screw internal fixation.
2026 Vol. 43 (9): 1439-1442 [
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1443
Effect of Narrative Nursing Intervention Model on Lung Cancer Patients Experiencing Adverse Reactions after Immunotherapy
JIA Yanan,ZHANG Yongjing,JIN Xiaoran
DOI: 10.3969/j.issn.1671-7171.2026.09.010
【Objective】 To investigate the effect of a narrative nursing intervention model on lung cancer patients who experienced adverse reactions after treatment with immune checkpoint inhibitors. 【Methods】 A total of 66 lung cancer patients with immunotherapy-related adverse reactions (≥ grade 2 according to CTCAE) admitted from January 2024 to February 2025 were randomly divided into an observation group and a control group, with 33 patients in each group. Both groups received routine nursing care, while the observation group additionally received narrative nursing intervention. The incidence of new adverse reactions within 4 weeks after intervention, time to adverse reaction relief, anxiety and depression levels [assessed using the Hospital Anxiety Scale (HAMA-14) and Hospital Depression Scale (HAMD-17)], and self-efficacy [assessed using the Strategies Used by People to Promote Health (SUPPH) scale] were compared between the two groups. 【Results】The overall incidence of adverse reactions in the observation group was 21.21% (7/33), which was significantly lower than that in the control group [45.45% (15/33)] (P<0.05). The relief times of rash, pruritus, thyroid dysfunction, gastrointestinal diarrhea, and immune-related pneumonia were shorter in the observation group than in the control group (all P<0.05). After 4 weeks of intervention, the anxiety and depression scores in the observation group were lower than those in the control group (all P<0.05), while all dimensions of the SUPPH scores were higher than those in the control group (all P<0.05). 【Conclusion】The narrative nursing intervention model can significantly reduce the incidence of immunotherapy-related adverse reactions, shorten the duration of adverse reactions, and improve patients' anxiety, depression, and self-efficacy in lung cancer patients.
2026 Vol. 43 (9): 1443-1446 [
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1447
Effects of Electroacupuncture Combined with Duhuo Jisheng Decoction on Lumbar Function and Inflammatory Cytokines in Patients with Non-Specific Low Back Pain
ZHANG Wenying
DOI: 10.3969/j.issn.1671-7171.2026.09.011
【Objective】To explore the effects of electroacupuncture combined with Duhuo Jisheng Decoction on lumbar function and inflammatory cytokines in patients with non-specific low back pain (NLBP). 【Methods】The clinical data of 121 patients with NLBP treated at Fangcheng County Hospital of Traditional Chinese Medicine from January 2023 to January 2024 were retrospectively analyzed. According to the different treatment methods, the patients were divided into an observation group (n=62, receiving electroacupuncture combined with Duhuo Jisheng Decoction) and a control group (n=59, receiving Duhuo Jisheng Decoction alone). The degree of low back pain, lumbar function, lumbar range of motion, overall response rate, overall incidence of adverse reactions, and serum levels of tumor necrosis factor α (TNF-α), interleukin-1β (IL-1β), and nucleotide-binding domain leucine-rich repeat and pyrin domain-containing receptor 3(NLRP3) were compared between the two groups. 【Results】One month after treatment, the Visual Analogue Scale (VAS) score, Quebec Back Pain Disability Scale (QBPDS) score, and Oswestry Disability Index (ODI) score of both groups were lower than those before treatment (all P<0.05), and the above indicators in the observation group were lower than those in the control group (all P<0.05). One month after treatment, the extension range of motion and flexion range of motion of both groups were greater than those before treatment (all P<0.05), and the above indicators in the observation group were greater than those in the control group (all P<0.05). The overall response rate of the observation group was higher than that of the control group (P<0.05). One month after treatment, the serum levels of TNF-α, IL-1β, and NLRP3 in both groups were lower than those before treatment (all P<0.05), and the above indicators in the observation group were lower than those in the control group (all P<0.05). There was no statistically significant difference in the overall incidence of adverse reactions between the two groups (P>0.05). 【Conclusion】Electroacupuncture combined with Duhuo Jisheng Decoction has a definite therapeutic effect on patients with NLBP: it can improve lumbar function, alleviate low back pain, and inhibit the serum expression of TNF-α, IL-1β, and NLRP3, with a favorable safety profile.
2026 Vol. 43 (9): 1447-1450 [
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1451
Effects of Patient-Controlled Epidural Analgesia Using Ropivacaine Combined with Sufentanil on Labor Progress and Fever in Women Undergoing Labor Analgesia
ZHANG Yanxia
DOI: 10.3969/j.issn.1671-7171.2026.09.012
【Objective】To investigate the effects of patient-controlled epidural analgesia (PCEA) using ropivacaine combined with sufentanil on labor progress and fever in women undergoing labor analgesia. 【Methods】 A total of 96 women who underwent labor analgesia at Minquan County Hospital of Traditional Chinese Medicine from January 2020 to December 2023 were randomly divided into a control group and an observation group, with 48 cases in each group. Both groups received PCEA. The control group received ropivacaine alone, whereas the observation group received ropivacaine combined with sufentanil. The analgesic effects, duration of labor, mode of delivery, and neonatal Apgar scores after delivery were compared between the two groups. Oxidative stress indicators [endothelin, cortisol, and superoxide dismutase (SOD)] and inflammatory factors [interleukin-6 (IL-6), interleukin-10(IL-10), and tumor necrosis factor α (TNF-α)] were measured before analgesia and 1 h after delivery. Visual analog scale (VAS) scores and body temperature were assessed before analgesia, 1 h after analgesia, immediately after delivery, and 1 h after delivery. 【Results】Compared with the control group, the observation group had a shorter onset time of anesthesia, fewer patient-controlled analgesia administrations, and a lower dose of local anesthetic, but a longer duration of anesthesia maintenance (all P<0.05). VAS scores at 1 h after analgesia, immediately after delivery, and 1 h after delivery were lower in the observation group than in the control group (all P<0.05). The rate of vaginal delivery was higher in the observation group than in the control group, and neonatal Apgar scores at 1 and 5 min after delivery were also higher (all P<0.05). 1 h after delivery, the levels of oxidative stress indicators and inflammatory factors in both groups were higher than those before analgesia (all P<0.05); however, the levels of these markers in the observation group were lower than those in the control group (all P<0.05). Body temperatures immediately after delivery and 1 h after delivery in the observation group were lower than those in the control group (all P<0.05). 【Conclusion】PCEA with ropivacaine combined with sufentanil can effectively improve analgesic efficacy, shorten the duration of labor, alleviate postpartum oxidative stress and inflammation, and reduce the risk of elevated maternal body temperature. It is worthy of clinical application.
2026 Vol. 43 (9): 1451-1454 [
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1455
Application Effect of Hypoglycemia Risk Stratified Management Intervention Based on the Andrew Scale in Elderly Patients with Diabetes Mellitus
ZHU Mingjun
DOI: 10.3969/j.issn.1671-7171.2026.09.013
【Objective】To explore the application effect of hypoglycemia risk stratified management based on the Andrew Scale in elderly patients with diabetes mellitus.【Methods】A total of 112 elderly patients with diabetes mellitus diagnosed and treated at the First Affiliated Hospital of Henan University of Science and Technology from December 2021 to December 2024 were selected and divided into a control group and an observation group using a random number table method, with 56 cases in each group. The control group received routine nursing management intervention, and the observation group received hypoglycemia risk stratified management intervention based on the Andrew Scale. The incidence of hypoglycemia, mastery of hypoglycemia knowledge, glycemic indicators [fasting plasma glucose (FPG), 2-hour postprandial plasma glucose (2hPPG), glycosylated hemoglobin], and nursing satisfaction were compared between the two groups.【Results】The incidence of hypoglycemia in the observation group was lower than that in the control group, and nursing satisfaction was higher than that in the control group, with statistically significant differences (all P<0.05). After nursing, the scores of mastery of knowledge regarding the causes, symptoms, harms, management, and prevention of hypoglycemia in both groups were higher than those before nursing, and the scores in the observation group were higher than those in the control group, with statistically significant differences (all P<0.05). After nursing, the levels of FPG, 2hPPG, and glycosylated hemoglobin in both groups were lower than those before nursing, and the levels in the observation group were lower than those in the control group, with statistically significant differences (all P<0.05).【Conclusion】The hypoglycemia risk stratified management intervention based on the Andrew Scale applied to elderly patients with diabetes mellitus can effectively control blood glucose levels and reduce the incidence of hypoglycemia, as well as improve patients' mastery of hypoglycemia knowledge and nursing satisfaction.
2026 Vol. 43 (9): 1455-1458 [
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1459
Effects of Knowledge-Attitude-Practice Transitional Intervention on Pulmonary Function and Parental Care Ability in Children with Severe Pneumonia Treated by Fiberoptic Bronchoscope Bronchoalveolar Lavage
LIU Hejinga,YAO Chuanb,LIANG Jinlingc
DOI: 10.3969/j.issn.1671-7171.2026.09.014
【Objective】 To explore the effects of knowledge-attitude-practice (KAP) transitional intervention on pulmonary function and parental care ability in children with severe pneumonia treated by fiberoptic bronchoscope bronchoalveolar lavage.【Methods】 A total of 92 children with severe pneumonia who received fiberoptic bronchoscope bronchoalveolar lavage in First People's Hospital of Nanyang City from February 2021 to February 2024 were selected and divided into the observation group (receiving knowledge-attitude-practice transitional intervention) and the control group (receiving routine intervention) by random number table method, with 46 cases in each group. The rehabilitation effect, pulmonary function indicators [forced expiratory volume in one second (FEV
1
), forced vital capacity (FVC), and FEV
1
/FVC ratio], inflammatory factors [interleukin-6 (IL-6), tumor necrosis factor α (TNF-α) and C-reactive protein (CRP)], parental negative emotions, parental care ability and complication incidence were compared between the two groups.【Results】 After intervention, the symptom relief time of children in the observation group was shorter than that in the control group (P<0.05). One week after intervention, FEV
1
, FVC and FEV
1
/FVC in the observation group were higher than those in the control group (all P<0.05). Two weeks after intervention, the levels of IL-6, TNF-α and CRP in children of the observation group were lower than those in the control group (P<0.05); the score of parental negative emotions was lower while the score of parental care ability was higher in the observation group than in the control group (P<0.05). The total incidence of complications in the observation group was lower than that in the control group (P<0.05).【Conclusion】 Knowledge-attitude-practice transitional intervention exerts positive effects on rehabilitation of children with severe pneumonia after fiberoptic bronchoscope bronchoalveolar lavage. It can effectively improve children’s pulmonary function and enhance parental care ability.
2026 Vol. 43 (9): 1459-1462 [
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1463
Efficacy of Huisheng Oral Liquid Combined with Osimertinib in the Treatment of Patients with Advanced Non-Small Cell Lung Cancer
CHEN Qingpo
DOI: 10.3969/j.issn.1671-7171.2026.09.015
【Objective】 To evaluate the efficacy of Huisheng Oral Liquid combined with osimertinib in the treatment of patients with advanced non-small cell lung cancer (NSCLC). 【Methods】 A total of 72 patients with advanced NSCLC admitted from May 2020 to August 2022 were randomly divided into a control group and an observation group, with 36 cases in each group. The control group received oral osimertinib alone, while the observation group received Huisheng Oral Liquid in addition to osimertinib. Clinical efficacy, tumor marker levels [cyto-keratin 19 fragment antigen 21-1(CYFRA21-1), neuron-specific enolase (NSE), and squamous cell carcinoma antigen (SCCAg)], immune function indices (CD4
+
T cells, CD8
+
T cells, CD3
+
T cells), and adverse drug reactions were compared between the two groups before and after treatment. Patients were followed up for 3 years, and overall survival (OS) and progression-free survival (PFS) were compared between the two groups. 【Results】 After treatment, the objective response rate and overall response rate in the observation group were significantly higher than those in the control group (P<0.05). The levels of CYFRA21-1, NSE, and SCCAg in the observation group were significantly lower than those in the control group (P<0.05). The observation group showed higher CD4
+
and CD3
+
levels and lower CD8
+
levels compared to the control group (P<0.05). The overall incidence of adverse reactions was lower in the observation group than in the control group (P<0.05). The median OS and PFS were significantly longer in the observation group than in the control group (P<0.05). 【Conclusion】 Huisheng Oral Liquid combined with osimertinib can significantly improve the efficacy in patients with advanced NSCLC, reduce tumor marker levels, enhance immune function, alleviate side effects, and improve survival outcomes.
2026 Vol. 43 (9): 1463-1465 [
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1466
Pathogen Distribution and Drug Resistance Analysis in Patients with Type 2 Diabetes Mellitus Complicated by Urinary Tract Infection
JIA Weiwei
DOI: 10.3969/j.issn.1671-7171.2026.09.016
【Objective】 To investigate the pathogen distribution and drug-resistance characteristics in patients with type 2 diabetes mellitus (T2DM) complicated by urinary tract infection. 【Methods】 A total of 120 T2DM patients complicated with urinary tract infection admitted to Jiyuan People's Hospital from January 2022 to December 2025 were enrolled. The patients were divided into group A (asymptomatic urinary tract infection) and group B (symptomatic urinary tract infection), with 60 cases in each group. Urine routine tests were performed for all patients. The two groups were compared in terms of age, gender, blood-glucose control and urine-culture results. The distribution characteristics of pathogens were analyzed, and the drug resistance of major pathogens was compared between the two groups. 【Results】 Statistically significant differences were found between the two groups in age, gender composition, fasting blood-glucose, glycosylated hemoglobin (HbA1c), blood urea nitrogen (BUN) and serum creatinine (Scr) (all P<0.05). A total of 48 strains of pathogens were isolated in group A and 59 strains in group B. Gram-negative bacteria were predominant in both groups: 34 Gram-negative strains (including 14 strains of Escherichia coli) in group A, and 41 Gram-negative strains (including 29 strains of Escherichia coli) in group B. Fourteen and eighteen Gram-positive strains were isolated from group A and group B respectively, among which 5 strains and 16 strains were Enterococcus faecalis. Drug-resistance analysis showed that Escherichia coli from both groups presented high resistance to ampicillin, piperacillin and cotrimoxazole; group B showed significantly higher resistance to piperacillin and cotrimoxazole than group A (all P<0.05). Enterococcus faecalis in both groups had high resistance to tetracycline, and the resistance rate in group B was higher than that in group A (P<0.05). 【Conclusion】 Both asymptomatic and symptomatic urinary tract infections in T2DM patients are mainly caused by Gram-negative bacteria, predominantly Escherichia coli, which shows high resistance to ampicillin, piperacillin and cotrimoxazole. For Gram-positive bacteria represented by Enterococcus faecalis, high tetracycline resistance is observed.
2026 Vol. 43 (9): 1466-1469 [
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1470
Influencing Factors of Hyponatremia in Patients with Non-Severe Traumatic Brain Injury
FAN Shuai,KONG Lingchang,ZHANG Dongwei
DOI: 10.3969/j.issn.1671-7171.2026.09.017
【Objective】 To explore the influencing factors of hyponatremia in patients with non-severe traumatic brain injury (non-sTBI).【Methods】 A total of 82 patients with non-sTBI admitted to Zhengzhou Hospital of Traditional Chinese Medicine from January 2018 to October 2024 were enrolled. They were divided into hyponatremia group (n=30) and non-hyponatremia group (n=52) according to the occurrence of hyponatremia. Clinical data were compared between the two groups. Multivariate Logistic regression analysis was performed to identify the influencing factors for hyponatremia in non-sTBI patients.【Results】 The proportions of patients with GCS score ≤12, skull-base fracture, subarachnoid hemorrhage, fever, vomiting and dehydrant use in the hyponatremia group were significantly higher than those in the non-hyponatremia group (all P<0.05). Multivariate Logistic regression analysis demonstrated that GCS score ≤12, skull-base fracture, subarachnoid hemorrhage, fever, vomiting and dehydrant use were risk factors for hyponatremia in non-sTBI patients (all P<0.05).【Conclusion】 GCS score ≤12, skull-base fracture, subarachnoid hemorrhage, fever, vomiting and dehydrant use are risk factors for hyponatremia in patients with non-severe traumatic brain injury. Clinicians should timely identify high-risk patients for hyponatremia and implement targeted interventions.
2026 Vol. 43 (9): 1470-1473 [
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1474
Comparison of the Effects of Esketamine and Dexmedetomidine Anesthesia in Elderly Patients Undergoing Lower Limb Fracture Surgery
HENG Lei,WANG Han,LI Jinjin
DOI: 10.3969/j.issn.1671-7171.2026.09.018
【Objective】To investigate the effects of esketamine and dexmedetomidine (Dex) anesthesia in elderly patients undergoing lower limb fracture surgery. 【Methods】 A total of 90 elderly patients with lower limb fractures admitted to Taikang County People's Hospital from January 2021 to January 2023 were randomly divided into an observation group (receiving esketamine anesthesia) and a control group (receiving Dex anesthesia), with 45 patients in each group. The anesthetic effects, perioperative indicators, and incidence of adverse reactions were compared between the two groups. Heart rate (HR) and mean arterial pressure (MAP) were recorded before anesthesia (T
0
), 5 min after anesthesia (T
1
), 30 min after anesthesia (T
2
), and at the end of surgery (T
3
). Pain status [assessed by the Visual Analogue Scale (VAS)] and cognitive function [assessed by the Mini-Mental State Examination (MMSE) score] were evaluated before and after surgery. 【Results】There were no statistically significant differences between the two groups in the excellent and good anesthesia rate, operation time, or anesthesia duration (all P>0.05). The recovery time and post-anesthesia care unit (PACU) stay time in the observation group were shorter than those in the control group (P<0.05). No significant differences were observed in HR or MAP between the two groups at T
0
and T
1
(all P>0.05). In the observation group, HR and MAP at T
2
and T
3
showed no significant differences compared with those at T
0
and T
1
(P>0.05). In the control group, HR and MAP at T
2
and T
3
were lower than those at T
0
and T
1
(P>0.05), while HR and MAP at T
2
and T
3
in the observation group were higher than those in the control group (P<0.05). After treatment, VAS scores in both groups were significantly lower than those before treatment (P<0.05), but there was no significant difference between the groups (P>0.05). The MMSE score in the observation group after treatment was higher than that before treatment. Also, the MMSE score in the observation group after treatment was higher than that in the control group (P<0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05). 【Conclusion】 Both esketamine and Dex anesthesia are safe and effective for elderly patients undergoing lower limb fracture surgery. However, esketamine anesthesia is beneficial for postoperative recovery, provides more stable hemodynamics, and may contribute to improving cognitive function.
2026 Vol. 43 (9): 1474-1477 [
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1478
Effects of Intravenous Thrombolysis with Alteplase on Serum sCD163 and ANGPTL3 Levels in Patients with Acute Cerebral Infarction
WANG Yachan,CHEN Yufei,WANG Qiuju
DOI: 10.3969/j.issn.1671-7171.2026.09.019
【Objective】To investigate the effects of intravenous thrombolysis with alteplase on serum soluble CD163 (sCD163) and angiopoietin-like protein 3 (ANGPTL3) levels in patients with acute cerebral infarction (ACI). 【Methods】Eighty patients with ACI admitted to our hospital between August 2021 and August 2024 were enrolled as the observation group, while 80 healthy individuals undergoing physical examinations during the same period were selected as the control group. According to the National Institutes of Health Stroke Scale (NIHSS) score at admission, patients in the observation group were classified into the mild group (n=35) and severe group (n=45). Based on the modified Rankin Scale score at 3 months after thrombolysis, patients were further divided into the favorable-prognosis group (n=56) and poor-prognosis group (n=24). Serum sCD163 and ANGPTL3 concentrations were measured. Spearman correlation analysis was performed to evaluate the associations of these biomarkers with the severity of neurological impairment. Receiver operating characteristic (ROC) curves were constructed to assess the predictive value for prognosis after thrombolysis. 【Results】 Before thrombolysis, serum sCD163 and ANGPTL3 levels were higher in the observation group than in the control group; and the levels of serum sCD163 and ANGPTL3 in the severe group were higher than those in the mild group (P<0.05). Both serum sCD163 and ANGPTL3 biomarkers were positively correlated with the severity of neurological impairment (P<0.05). Levels of sCD163 and ANGPTL3, both before and after thrombolysis, were higher in the poor-prognosis group than in the favorable-prognosis group (P<0.05). ROC analysis showed that the combined assessment of sCD163 and ANGPTL3 yielded an area under the curve of 0.952 for predicting prognosis after thrombolysis, with a sensitivity of 95.8% and a specificity of 98.2%, outperforming either marker alone (P<0.05). 【Conclusion】 Serum sCD163 and ANGPTL3 levels are elevated in patients with ACI and they are associated with the severity of neurological impairment and clinical prognosis.
2026 Vol. 43 (9): 1478-1480 [
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1481
Application of Multidisciplinary Team Collaboration Combined with AIDET Communication Model in Perioperative Period of Patients Undergoing TRI-PCI
YANG Kaili,LIU Xiaopeng
DOI: 10.3969/j.issn.1671-7171.2026.09.020
【Objective】To investigate the application effect of multidisciplinary team (MDT) collaboration combined with the AIDET communication model in the perioperative period of patients with coronary heart disease undergoing transradial approach for percutaneous coronary intervention (TRI-PCI). 【Methods】A total of 116 patients with coronary heart disease who underwent TRI-PCI in Luoyang Dongfang People's Hospital from May 2022 to May 2025 were selected. Patients were divided into a control group and an observation group by the random number table method, with 58 cases in each group. Patients in the control group received routine perioperative nursing, while those in the observation group received MDT combined with the AIDET communication model intervention on the basis of the control group. The puncture conditions (puncture success rate, puncture time, radial artery spasm, local hematoma, radial artery occlusion, and time to removal of hemostatic compression), coagulation function indicators [prothrombin time (PT), D-dimer (D-D), and fibrinogen degradation products (FDP)], and the incidence of postoperative complications were compared between the two groups. 【Results】There were no statistically significant differences in the incidences of radial artery spasm, local hematoma, or radial artery occlusion between the two groups (all P>0.05). The puncture success rate in the observation group was higher than that in the control group, while puncture time and time to removal of hemostatic compression were shorter than those in the control group, with statistically significant differences (all P<0.05). After intervention, PT, D-D, and FDP levels in both groups were lower than those before intervention; and the above indicators in the observation group were lower than those in the control group, with statistically significant differences (all P<0.05). The incidence of postoperative complications in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). 【Conclusion】MDT collaboration combined with the AIDET communication model can significantly optimize the quality of perioperative management in patients undergoing TRI-PCI, enhance the puncture success rate, improve coagulation function, and reduce the incidence of postoperative complications.
2026 Vol. 43 (9): 1481-1484 [
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1485
Application and Effect of Solution-Focused Model Intervention in Patients with Arrhythmia
YANG Yanan,LI Ting,HAN Yuanli
DOI: 10.3969/j.issn.1671-7171.2026.09.021
【Objective】To investigate the application effect of solution-focused mode intervention in patients with arrhythmia. 【Methods】A total of 102 patients with arrhythmia admitted to Kaifeng Central Hospital from October 2024 to December 2025 were selected. They were divided into a control group (receiving routine nursing intervention) and an observation group (receiving solution-focused mode intervention) by the random number table method, with 51 patients in each group. The cardiac function indicators [left ventricular end-diastolic diameter (LVEDD), ratio of peak early diastolic mitral flow velocity to peak atrial systolic flow velocity (E/A), left ventricular ejection fraction (LVEF), left ventricular end-systolic volume index (LVESVI)], coping styles [Coping Style Questionnaire (CSQ) scores], self-care ability [Exercise of Self-Care Agency Scale (ESCA) scores], and quality of life [China Questionnaire of Quality of Life in Patients with Cardiovascular Diseases (CQQC) scores] were compared between the two groups before and after intervention. 【Results】After 3 months of intervention, LVEF in both groups was higher than that before intervention, while LVEDD, E/A, and LVESVI were lower than those before intervention. LVEF in the observation group was higher than that in the control group, while LVEDD, E/A, and LVESVI were lower than those in the control group, with statistically significant differences (all P<0.05). The scores of self-blame, fantasy, and retreat in both groups were lower than those before intervention, while the scores of help-seeking, problem-solving, and rationalization were higher than those before intervention; the scores of self-blame, fantasy, and retreat in the observation group were lower than those in the control group, while the scores of help-seeking, problem-solving, and rationalization were higher than those in the control group, with statistically significant differences (all P<0.05). The scores of health knowledge, self-care skills, self-concept, and self-responsibility in both groups were higher than those before intervention, and the above scores in the observation group were higher than those in the control group, with statistically significant differences (all P<0.05). The scores of medical condition, disease condition, physical strength, general life, psychosocial status, and work status in both groups were higher than those before intervention, and the above scores in the observation group were higher than those in the control group, with statistically significant differences (all P<0.05). 【Conclusion】 Solution-focused mode intervention is helpful to improve cardiac function, enhance self-care ability and quality of life, and promote positive coping styles in patients with arrhythmia.
2026 Vol. 43 (9): 1485-1488 [
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1489
Predictive Value of Echocardiography Combined with D-Dimer for Acute Pulmonary Embolism in Patients with Chronic Obstructive Pulmonary Disease
ZHANG Hang,ZHAO Bing,GAO Yafei
DOI: 10.3969/j.issn.1671-7171.2026.09.022
【Objective】To explore the predictive value of echocardiography combined with D-dimer for acute pulmonary embolism in patients with chronic obstructive pulmonary disease (COPD).【Methods】A total of 112 patients with COPD admitted to Luoyang Central Hospital from January 2021 to January 2024 were selected and divided into an observation group (those who developed acute pulmonary embolism, n=29) and a control group (those who did not develop acute pulmonary embolism, n=83) according to whether acute pulmonary embolism occurred. All patients underwent echocardiography after admission. The pulmonary artery diameter, right ventricular diameter, right atrial diameter, right ventricular performance index, and D-dimer level were compared between the two groups. Multivariate logistic regression analysis was used to analyze the risk factors for acute pulmonary embolism in patients with COPD, and the receiver operating characteristic (ROC) curve was used to evaluate the efficacy of echocardiography combined with D-dimer in predicting acute pulmonary embolism in patients with COPD.【Results】The pulmonary artery diameter, right ventricular diameter, and right atrial diameter of the patients in the observation group were all greater than those in the control group, and the right ventricular performance index and D-dimer level were higher than those in the control group, with statistically significant differences (all P<0.05). Multivariate logistic regression analysis showed that a larger pulmonary artery diameter, right ventricular diameter, and right atrial diameter, as well as a higher right ventricular performance index and D-dimer level, were all risk factors for acute pulmonary embolism in patients with COPD (all P<0.05), and the area under the curve of echocardiography combined with serum D-dimer level detection for predicting acute pulmonary embolism in patients with COPD was 0.975.【Conclusion】Echocardiography combined with serum D-dimer level detection has high efficacy in predicting acute pulmonary embolism in patients with COPD, and can provide a reference for the diagnosis and treatment of patients with COPD.
2026 Vol. 43 (9): 1489-1492 [
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1493
Effects of Pharmacy-Nursing Management Intervention on Medication Compliance and Self-Care Ability in Elderly Patients with Polypharmacy
WANG Jianing,WANG Kaixuan,GUO Yu
DOI: 10.3969/j.issn.1671-7171.2026.09.023
【Objective】 To explore the effects of pharmacy-nursing management intervention on medication compliance and self-care ability in elderly patients with polypharmacy. 【Methods】 A total of 86 elderly in-hospital patients with multiple comorbidities admitted to Zhoukou Orthopedic Hospital from January 2021 to January 2023 were selected. The patients were divided into the control group (receiving routine medication management) and the observation group (receiving pharmacy-nursing management intervention) by random number table method, with 43 cases in each group. Medication compliance, self-care ability and quality of life were compared between the two groups, and adverse drug reactions during medication were recorded. 【Results】 After 3-month intervention, the MMAS-8 scores of both groups were higher than those before intervention, and the observation group obtained higher scores than the control group (all P<0.05). The scores of self-care skill, self-care responsibility, self-concept and health knowledge level in both groups increased after intervention; the above-mentioned scores in the observation group were higher than those in the control group (all P<0.05). The 36-Item Short Form Health Survey(SF-36) scores of both groups improved after intervention, and the observation group was superior to the control group (all P<0.05). The incidence of adverse reactions in the observation group was 20.93% (9/43), which was lower than 51.16% (22/43) in the control group (χ
2
=8.524,P=0.0035). 【Conclusion】 Pharmacy-nursing management intervention can help improve medication compliance, self-care ability and quality of life, and reduce the risk of adverse reactions in elderly patients with polypharmacy.
2026 Vol. 43 (9): 1493-1495 [
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1496
The Effect of Family Empowerment Model on Immune Function and Treatment Compliance in Patients Undergoing Hematopoietic Stem Cell Transplantation
YANG Juanjuan
DOI: 10.3969/j.issn.1671-7171.2026.09.024
【Objective】 To explore the effect of family empowerment model on immune function and treatment compliance in patients undergoing hematopoietic stem cell transplantation (HSCT). 【Methods】A total of 86 HSCT patients admitted to Nanyang Central Hospital from June 2022 to June 2025 were enrolled and divided into observation group and control group by random number table method, with 43 cases in each group. The control group received routine nursing during the peri-transplantation period of HSCT, while the observation group received family empowerment model intervention on the basis of routine nursing. The immune function indicators (CD4
+
, CD8
+
, CD4
+
/CD8
+
ratio), treatment compliance, Connor-Davidson Resilience Scale (CD-RISC) scores, and Revised Piper Fatigue Scale (RPFS) scores for cancer-related fatigue were compared between the two groups before intervention and at 6 months after intervention. 【Results】At 6 months after intervention, CD8
+
levels decreased while CD4
+
levels and CD4
+
/CD8
+
ratio increased in both groups compared with baseline; the observation group had lower CD8
+
level and higher CD4
+
level and CD4
+
/CD8
+
ratio than the control group, with statistically significant differences (all P<0.05). The scores of medication adherence including taking medicine on time and persistent medication were elevated in both groups after intervention, and these scores were higher in the observation group (all P<0.05). The scores of tenacity, strength, optimism, family support and interpersonal assistance were higher after intervention in both groups, and the observation group achieved higher scores than the control group (all P<0.05). The scores of cognition-emotion, affection, behavior, severity and sensory dimension of fatigue were reduced in both groups after intervention, and the observation group showed lower scores than the control group (all P<0.05). 【Conclusion 】 Family empowerment model can improve immune function, enhance treatment compliance and psychological resilience, and relieve cancer-related fatigue in HSCT patients.
2026 Vol. 43 (9): 1496-1499 [
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1500
Effect of Double-Tract Folded Jejunal Interposition and Esophagojejunostomy Roux-en-Y Anastomosis on Postoperative Gastroesophageal Reflux and Gastrointestinal Function in Patients with Tumor of Gastroesophageal Junction
WANG Shuisheng,ZHAO Chunlin,JIN Xiaoran,GAO Lei
DOI: 10.3969/j.issn.1671-7171.2026.09.025
【Objective】To investigate the effects of double-tract folded jejunal interposition and Roux-en-Y esophagojejunostomy on gastroesophageal reflux and gastrointestinal function in patients with tumor of gastroesophageal junction. 【Methods】The clinical data of 86 patients with tumor of gastroesophageal junction who underwent total gastrectomy at Zhengzhou Central Hospital Affiliated to Zhengzhou University and The First Affiliated Hospital of Zhengzhou University from March 2023 to March 2024 were retrospectively analyzed. According to different digestive tract reconstruction methods, the patients were divided into a control group (Roux-en-Y esophagojejunostomy) and an observation group (double-tract folded jejunal interposition), with 43 cases in each group. The perioperative indicators, gastroesophageal reflux, postoperative gastrointestinal function recovery indicators (time to recovery of bowel sounds, time to relief of gastrointestinal discomfort, time to first defecation), nutritional indicators [total protein (TP), albumin (Alb), hemoglobin (Hb)], and the incidence of postoperative complications were compared between the two groups. 【Results】There were no statistically significant differences in the time of digestive tract reconstruction, intraoperative blood loss, postoperative extubating time, time to first oral intake, time to first flatus, or length of hospital stay between the two groups (all P>0.05). The GerdQ scores at 1, 3, and 6 months after surgery in both groups were lower than those before surgery, and these GerdQ scores in the observation group were lower than those in the control group, with statistically significant differences (all P<0.05). At 6 months after surgery, the proportion of patients diagnosed with reflux esophagitis by endoscopy in both groups was lower than that before surgery, and the proportion in the observation group was lower than that in the control group, with statistically significant differences (all P<0.05). The time to recovery of bowel sounds, time to relief of gastrointestinal discomfort, and time to first defecation in the observation group were shorter than those in the control group, with statistically significant differences (all P<0.05). At 6 months after surgery, the serum levels of TP, Alb, and Hb in both groups were higher than those before surgery, and these levels in the observation group were higher than those in the control group, with statistically significant differences (all P<0.05). The total incidence of postoperative complications in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). 【Conclusion】In patients with tumor of gastroesophageal junction undergoing total gastrectomy, the perioperative indicators of double-tract folded jejunal interposition and traditional Roux-en-Y esophagojejunostomy are comparable. However, double-tract folded jejunal interposition can offer better anti-reflux effect, promote gastrointestinal function recovery, improve nutritional status, and reduce the incidence of complications.
2026 Vol. 43 (9): 1500-1503 [
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1504
Effect of a Family-Involved Individualized Nursing Plan on Convulsions in Children
ZHANG Doudou,TIAN Fei,CUI Yufeng
DOI: 10.3969/j.issn.1671-7171.2026.09.026
【Objective】To investigate the application of a family-involved individualized nursing plan in pediatric convulsions. 【Methods】A total of 100 children with convulsions admitted to Luoyang Maternity and Child Health Care Hospital from January 2023 to April 2025 were enrolled. They were divided into the control group (receiving routine nursing) and the observation group (receiving a family-involved individualized nursing plan in addition to routine nursing) using a random number table method, with 50 children in each group. The frequency and severity of convulsions, nursing adherence, quality of life [Pediatric Quality of Life Inventory Version 4.0 Generic Core Scales (PedsQL 4.0)], and recurrence rate of convulsions were compared between the two groups before intervention and 3 months after intervention. 【Results】After 3 months of intervention, the frequency and severity scores of convulsions in the observation group were lower than those in the control group, and the differences were statistically significant (all P<0.05). The nursing adherence scores in both groups were higher than those before intervention, while the nursing adherence scores in the observation group was higher than that in the control group, with statistically significant differences (all P<0.05). The scores of physical functioning, social functioning, emotional functioning, and role functioning in both groups were higher than those before intervention, and the above dimension scores in the observation group were higher than those in the control group, with statistically significant differences (P<0.05). After 3 months of intervention, the recurrence rate of convulsions in the observation group was significantly lower than that in the control group, and the difference was statistically significant (P<0.05). 【Conclusion】The family-involved individualized nursing plan has a favorable application effect in pediatric convulsions, which improves children's quality of life and nursing adherence.
2026 Vol. 43 (9): 1504-1507 [
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1508
Efficacy of Evolocumab Combined with Rosuvastatin in Patients with Cerebral Infarction Complicated with Intracranial and Extracranial Arterial Stenosis
DONG Peng,LIU Jieyi,LIU Ye,WU Minlu
DOI: 10.3969/j.issn.1671-7171.2026.09.027
【Objective】To analyze the clinical efficacy of combined application of evolocumab and rosuvastatin for patients suffering from cerebral infarction accompanied by intracranial and extracranial arterial stenosis. 【Methods】A total of 88 patients with cerebral infarction and intracranial and extracranial arterial stenosis treated from June 2023 to June 2025 were enrolled. Patients were divided into the control group and the observation group, with 44 cases in each group, according to treatment regimens. The control group received rosuvastatin monotherapy alone, while the observation group adopted the combined therapy of evolocumab and rosuvastatin. Clinical efficacy, blood lipid levels before and after treatment, relief time of clinical symptoms and incidence of adverse reactions were compared between two groups. 【Results】The observation group obtained higher overall clinical effective rate than the control group (all P<0.05). After treatment, the levels of total cholesterol (TC), triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) decreased, and high-density lipoprotein cholesterol (HDL-C) increased in the observation group compared to the control group, with significant differences(all P<0.05). The observation group showed obviously shorter relief time of various clinical symptoms (all P<0.05). No significant difference existed in the total incidence of adverse reactions between two groups (P>0.05). 【Conclusion】Combined treatment with both evolocumab and rosuvastatin improves therapeutic effect obviously, optimizes blood lipid metabolism effectively and shortens symptom relief time safely in patients with cerebral infarction complicate with intracranial and extracranial arterial stenosis.
2026 Vol. 43 (9): 1508-1510 [
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1511
Serum α-Hydroxybutyrate Dehydrogenase and Lactate Dehydrogenase Levels as Predictors of Prognosis in Patients with Intracerebral Hemorrhage
ZHANG Weiwei,CHANG Hui,SHI Zhipeng
DOI: 10.3969/j.issn.1671-7171.2026.09.028
【Objective】 To investigate the predictive value of serum α-hydroxybutyrate dehydrogenase (α-HBDH) and lactate dehydrogenase (LDH) levels for the prognosis of patients with intracerebral hemorrhage (ICH). 【Methods】 The clinical data of 101 patients with ICH admitted to Jinshui District General Hospital of Zhengzhou from March 2019 to March 2022 were retrospectively studied. According to their survival status within 28 days after admission, the patients were divided into a favorable-prognosis group (survivors) and an unfavorable-prognosis group (deaths). General clinical data and serum α-HBDH and LDH levels were compared between the two groups. Multivariate Logistic regression analysis was performed to identify factors associated with prognosis in patients with ICH. Receiver operating characteristic (ROC) curves were used to evaluate the predictive value of serum α-HBDH and LDH levels for prognosis in patients with ICH. 【Results】 Among the 101 patients with ICH, 77 survived within 28 days (the favorable-prognosis group) and 24 died (the unfavorable-prognosis group), yielding a mortality rate of 23.76% (24/101). There were no statistically significant differences between the two groups in terms of sex, age, body mass index, level of consciousness at admission, history of hypertension, history of hyperlipidemia, history of diabetes mellitus, fever at admission, time from onset to admission, treatment regimen, respiratory rate, or platelet count (all P>0.05). The unfavorable-prognosis group had a greater hemorrhage volume, a higher proportion of patients with multiple organ failure, and higher serum α-HBDH and LDH levels than the favorable-prognosis group (all P<0.05). Multivariate Logistic regression analysis showed that hemorrhage volume, multiple organ failure, and serum α-HBDH and LDH levels were independent risk factors for poor prognosis in patients with ICH (all P<0.05). ROC curve analysis showed that the area under the curve (AUC), sensitivity, and specificity of the combined α-HBDH and LDH model for predicting prognosis in patients with ICH were higher than those of either marker alone (all P<0.05). 【Conclusion】 Serum α-HBDH and LDH levels are closely associated with the prognosis of patients with ICH, and their combined detection provides greater predictive value for prognosis than either marker alone.
2026 Vol. 43 (9): 1511-1514 [
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1515
Effects of Green-Model Health Education on Post-Partum Sexual Life Quality and Pelvic Floor Function of Primiparas
LI Yang
DOI: 10.3969/j.issn.1671-7171.2026.09.029
【Objective】 To explore the effects of Green-model health education on post-partum sexual life quality and pelvic floor function of primiparas.【Methods】 A total of 310 primiparas who delivered in Zhengzhou Second People's Hospital from January 2023 to January 2025 were selected and divided into the control group and the observation group by random number table method, with 155 cases in each group. The control group received routine post-partum health education, while the observation group received Green-model health education on the basis of the control group. Pelvic floor function (Modified Oxford Grading Scale, MOS grade) and sexual life quality (Female Sexual Function Index, FSFI score) were compared between the two groups before and after intervention.【Results】 Before intervention, there was no statistically significant difference in MOS grade between the two groups of primiparas (P>0.05). After intervention, the rate of normal recovery of pelvic floor muscle function in the observation group was 83.23% (129/155), which was significantly higher than 56.77% (88/155) in the control group (P<0.05). Before intervention, there were no statistically significant differences in all dimensions of FSFI scores between the two groups (all P>0.05). After intervention, all-dimension FSFI scores of both groups were higher than those before intervention, and each dimension FSFI score in the observation group was higher than that in the control group, with statistically significant differences (all P<0.05).【Conclusion】 Green-model health education can effectively promote the recovery of pelvic floor function and improve post-partum sexual life quality of primiparas.
2026 Vol. 43 (9): 1515-1517 [
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1518
Application Effect of Self-Care Theory Combined with Predictive Strategy in the Management of Postpartum Urinary Retention
WANG Panpan,ZHOU Qin,WEN Zhiqi
DOI: 10.3969/j.issn.1671-7171.2026.09.030
【Objective】 To explore the application effect of self-care theory combined with predictive strategy in the management of postpartum urinary retention. 【Methods】A prospective controlled trial was conducted. A total of 120 puerperae who delivered in Zhengzhou Central Hospital Affiliated to Zhengzhou University from January 2022 to December 2023 were enrolled and divided into a control group (receiving routine nursing care) and an observation group (receiving nursing care based on self-care theory combined with predictive strategy) according to admission order, with 60 cases in each group. The incidence of postpartum urinary retention, bladder function, psychological status [assessed by the Edinburgh Postnatal Depression Scale (EPDS) and the Self-Perceived Burden Scale (SPBS) score], and the overall incidence of complications were compared between the two groups. 【Results】After the intervention, the overall incidence of postpartum urinary retention and the residual urine volume in the observation group were significantly lower than those in the control group (P<0.05); the time to first voiding was significantly shorter, and the single voided volume and maximum urinary flow rate were significantly higher than those in the control group (P<0.05). After the intervention, the EPDS and SPBS scores of both groups decreased significantly compared with their baseline levels, with the observation group scoring significantly lower than the control group (all P<0.05). The overall incidence of complications in the observation group was significantly lower than that in the control group (P<0.05). 【Conclusion】The application of self-care theory combined with predictive strategy in the management of postpartum urinary retention can effectively reduce the incidence of urinary retention, improve bladder function, promote psychological well-being, and lower the incidence of complications.
2026 Vol. 43 (9): 1518-1521 [
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