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Quick Search     Adv Search 2026 Vol. 43, No. 7 Published: 2026-07-26   1057 Application Effect of the PRECEDE Model Based on Action Research Method in Patients with Obstructive Sleep Apnea Syndrome CAO Guofang, FAN Cuihua DOI: 10.3969/j.issn.1671-7171.2026.07.001 【Objective】 To evaluate the effectiveness of PRECEDE model intervention based on action research method in patients with obstructive sleep apnea syndrome (OSAHS). 【Methods】 A total of 88 OSAHS patients admitted to our hospital from January 2022 to December 2024 were randomly divided into a control group (receiving routine care) and an observation group (receiving PRECEDE model intervention based on action research method), with 44 patients in each group. The respiratory disturbance index (AHI), daytime sleepiness level (Epworth Sleepiness Scale, ESS score), treatment adherence (daily use time of continuous positive airway pressure, CPAP device), general self-efficacy scale (GSES) scores, and quality of life (Sleep Apnea Quality of Life Index, SAQLI scores) were compared between the two groups. 【Results】 After intervention, the observation group showed significantly lower AHI and ESS scores than the control group, while it exhibited longer daily CPAP usage time, as well as higher GSES and SAQLI subscale scores compared to the control group, all differences were statistically significant (P<0.05). 【Conclusion】 PRECEDE model intervention based on action research method effectively improves sleep breathing conditions in OSAHS patients, reduces daytime sleepiness, enhances CPAP treatment adherence, self-efficacy, and quality of life. It is worthy of clinical promotion and application. 2026 Vol. 43 (7): 1057-1060 [Abstract] ( 47 ) HTML (1 KB)  PDF (1192 KB)  ( 6 ) 1061 Clinical Value of Combined Detection of CA125, CEA and BNP in Early Diagnosis of Left Heart Failure HAN Kaiwu, SHI Bian, LYU Huimei DOI: 10.3969/j.issn.1671-7171.2026.07.002 【Objective】 To explore the clinical application value of combined detection of carbohydrate antigen 125 (CA125), carcinoembryonic antigen (CEA) and brain natriuretic peptide (BNP) for early identification of left heart failure (LHF). 【Methods】 A total of 78 patients with early LHF admitted to the hospital from January 2021 to June 2024 were enrolled as the observation group, and 85 healthy volunteers undergoing physical examination during the same period were selected as the control group. Levels of CA125, CEA, BNP and cardiac function indicators including left ventricular ejection fraction (LVEF) and left ventricular end-diastolic volume (LVEDV) were compared between the two groups. Pearson correlation analysis was used to analyze the correlation among above indexes. Receiver operating characteristic (ROC) curve was adopted to evaluate the diagnostic efficacy of single and combined detection of CA125, CEA and BNP in early LHF. 【Results】 The levels of CA125, CEA and BNP in the observation group were significantly higher than those in the control group (P<0.05). LVEF in the observation group was obviously lower, while LVEDV was markedly higher than that in the control group (P<0.05). Pearson correlation analysis showed CA125, CEA and BNP were negatively correlated with LVEF and positively correlated with LVEDV (P<0.05). ROC curve analysis revealed combined detection of the three indexes presented the optimal diagnostic efficiency, with an area under the curve of 0.979, a sensitivity of 96.2% and a specificity of 96.5%. 【Conclusion】 The combined detection of CA125, CEA and BNP possesses important clinical significance for early diagnosis of LHF, and it can provide reference basis for clinical early intervention. 2026 Vol. 43 (7): 1061-1063 [Abstract] ( 41 ) HTML (1 KB)  PDF (1308 KB)  ( 7 ) 1064 Effects of Tongdu Tiaoshu Fuyang Tuina Combined with Basic Intervention on Growth and Quality of Life in Children with Short Stature LI Ya, LIN Lin, LI Cancan DOI: 10.3969/j.issn.1671-7171.2026.07.003 【Objective】 To investigate the effects of Tongdu Tiaoshu Fuyang Tuina combined with basic intervention on physical growth and quality of life in children with short stature. 【Methods】 A total of 60 children with short stature admitted to our hospital from June 2022 to June 2023 were enrolled and divided into control group and observation group by random number table, with 30 cases in each group. The control group received health education and intensive nutritional support, while the observation group was treated with Tongdu Tiaoshu Fuyang Tuina on the basis of the above basic interventions. The clinical efficacy, height increment, growth velocity, insulin-like growth factor-1 level, TCM syndrome scores and quality of life scores were compared between the two groups. 【Results】 The total clinical effective rate of the observation group was 86.67% (26/30), which was significantly higher than 46.67% (14/30) of the control group (χ2=10.800, P<0.05). The height increment and annual growth velocity in the observation group were superior to those of the control group (P<0.05). After treatment, serum insulin-like growth factor-1 levels increased and TCM syndrome scores decreased in both groups; the observation group obtained higher IGF-1 levels and lower TCM scores than the control group (P<0.05). The scores of school functioning, emotional functioning, physical functioning and social functioning were elevated in both groups after treatment, and the observation group achieved significantly higher scores (P<0.05). 【Conclusions】 Tongdu Tiaoshu Fuyang Tuina combined with basic intervention can significantly improve clinical efficacy, accelerate height growth, relieve TCM symptoms of spleen-kidney yang deficiency, and elevate the overall quality of life of children with short stature. 2026 Vol. 43 (7): 1064-1067 [Abstract] ( 30 ) HTML (1 KB)  PDF (1200 KB)  ( 4 ) 1068 Composition Analysis and Clinical Characteristics of 117 Cases of Urinary Calculi in Turpan Region Hasiyetiguli Maimaiti, LI Yong, SONG Xiaohang, LYU Wei DOI: 10.3969/j.issn.1671-7171.2026.07.004 【Objective】 To analyze the composition and clinical data of urinary calculi in patients from Turpan region, clarify the compositional characteristics and distribution rules of urinary calculi in this area, and provide a basic reference for clinical prevention and treatment. 【Methods】 A retrospective analysis was conducted on the clinical data of 118 patients with urinary tract stones admitted to the department of urology, Turpan People's Hospital, from June 2024 to October 2025. The stone compositions were detected using infrared spectroscopy. The overall distribution characteristics of stone components were analyzed, and comparisons were made regarding the detection rates of stone components, the sites of stone occurrence between different genders, and the distribution of major stone components across different age groups. 【Results】 After excluding 1 unqualified specimen, 117 valid samples were included. Calcium oxalate was the main component of the stones, with the detection rates of calcium oxalate monohydrate (76.07%, 89 cases), carbonate apatite (40.17%, 47 cases), and calcium oxalate dihydrate (37.61%, 44 cases), which were all higher than 30%. The detection rate of calcium oxalate monohydrate in females (87.50%) was significantly higher than that in males (70.13%), with a statistically significant difference (P<0.05). Mixed stones were the main type (58.97%), of which the most common combination was calcium oxalate monohydrate + calcium oxalate dihydrate + carbonate apatite (34.78%). Among simple -component stones, calcium oxalate monohydrate was dominant (68.75%). Patients were mainly aged 31-60 years (71.79%), and ureteral stones accounted for the highest proportion (68.38%) in the location of stone occurrence. There were no statistically significant differences in age distribution and stone location between different genders (P>0.05). 【Conclusion】 Urinary calculi in Turpan region are mainly composed of calcium oxalate, with a high proportion of mixed stones. The incidence characteristics are closely related to the local hot and arid climate and dietary habits. Individualized prevention and treatment plans should be formulated clinically based on stone composition and patient characteristics. 2026 Vol. 43 (7): 1068-1071 [Abstract] ( 35 ) HTML (1 KB)  PDF (1199 KB)  ( 4 ) 1072 Preoperative Differential Diagnostic Value of Serum Markers Combined with Conventional Ultrasound and Contrast-Enhanced Ultrasound for Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma JING Xiaoyun, FENG Shaoyang, XU Keke DOI: 10.3969/j.issn.1671-7171.2026.07.005 【Objective】 To explore the preoperative differential diagnostic value of serum markers combined with conventional ultrasound and contrast-enhanced ultrasound (CEUS) for hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). 【Methods】 A total of 124 patients with hepatocellular carcinoma (HCC group) and 116 patients with intrahepatic cholangiocarcinoma (ICC group) admitted to our hospital from January 2022 to November 2024 were enrolled. The levels of alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA), carbohydrate antigen 125 (CA125) and carbohydrate antigen 19-9 (CA19-9) were detected in both groups. All patients underwent conventional ultrasound and CEUS examinations. The serum marker levels, conventional ultrasonic features, CEUS manifestations and quantitative parameters were compared between the two groups. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the preoperative differential diagnostic efficacy of combined detection for HCC and ICC. 【Results】 The AFP level of the HCC group was higher than that of the ICC group, while the levels of CEA, CA125 and CA19-9 were lower in the HCC group (P<0.05). Statistically significant differences were observed between the two groups in conventional ultrasonic signs including irregular lesion shape, lesion echo, blurred boundary, bile duct dilatation and portal vein tumor thrombus (P<0.05). Significant intergroup differences were also found in CEUS features such as irregular shape, blurred boundary, homogeneous arterial phase enhancement and portal phase enhancement pattern (P<0.05). The arrival time and time to peak of the HCC group were longer than those of the ICC group (P<0.05). ROC curve analysis showed that the sensitivity, specificity and area under the curve (AUC) of combined serum markers, conventional ultrasound and CEUS for preoperative differentiation were 96.0%, 95.7% and 0.974 respectively, which were superior to single indicator detection. 【Conclusions】 The combined application of serum markers, conventional ultrasound and CEUS presents high sensitivity and specificity in the preoperative differentiation of HCC and ICC, which can effectively improve preoperative diagnostic accuracy and provide strong evidence for clinical diagnosis. 2026 Vol. 43 (7): 1072-1075 [Abstract] ( 34 ) HTML (1 KB)  PDF (1340 KB)  ( 4 ) 1076 Effect of Xingnao Kaiqiao Acupuncture Combined with Tongluo Jiejing Decoction on Motor Function and Muscle Tone in Patients with Stroke ZHANG Wenying DOI: 10.3969/j.issn.1671-7171.2026.07.006 【Objective】 To investigate the effect of Xingnao Kaiqiao acupuncture combined with Tongluo Jiejing decoction on motor function and muscle tone in patients with stroke. 【Methods】 Ninety-six stroke patients were randomly assigned into an observation group and a control group, with 48 cases in each. Patients in the control group received conventional rehabilitation exercises, while those in the observation group received Xingnao Kaiqiao acupuncture and Tongluo Jiejing decoction in addition to conventional rehabilitation. Neurological function [National Institutes of Health Stroke Scale (NIHSS)], motor function [upper extremity Fugl-Meyer Assessment (FMA)], balance status [Berg Balance Scale (BBS)], muscle tone [Composite Spasticity Index (CSI) and Modified Ashworth Scale (MAS)], traditional Chinese medicine (TCM) syndrome scores, and 6 minute walk speed and distance were compared between the two groups before treatment and at 1 and 4 weeks after treatment. 【Results】 After treatment, the observation group showed significantly lower NIHSS, CSI, MAS scores, and TCM syndrome scores compared to the control group, whereas BBS and FMA scores, as well as 6 minute walking speed and distance, were significantly improved (P<0.05 for all). 【Conclusion】 The combination therapy of Xingnao Kaiqiao acupuncture and Tongluo Jiejing decoction effectively alleviates spasticity and improves clinical outcomes in stroke patients. 2026 Vol. 43 (7): 1076-1078 [Abstract] ( 29 ) HTML (1 KB)  PDF (1240 KB)  ( 6 ) 1079 Application Effect of Arthroscopy-Assisted Minimally Invasive Reduction and Internal Fixation in Patients with Tibial Plateau Fractures ZHOU Zhixun, HUANG Shen, ZHOU Daoguang, DENG Xuguang, WEI Kunhuan, QIU Shanqin, ZHAI Jinhua, MO Ningfang DOI: 10.3969/j.issn.1671-7171.2026.07.007 【Objective】 To explore the application effect of arthroscopy-assisted minimally invasive reduction and internal fixation for patients with tibial plateau fractures. 【Methods】 A total of 80 patients with tibial plateau fractures admitted to our hospital from May 2021 to May 2025 were selected and divided into control group and observation group according to different surgical methods, with 40 cases in each group. The control group received open reduction and internal fixation, while the observation group was treated with arthroscopy-assisted minimally invasive reduction and internal fixation. Perioperative indicators (operation time, intraoperative blood loss, time to get out of bed after operation, time of full weight-bearing after operation), postoperative knee swelling, knee flexion and extension range of motion, knee joint function [American Knee Society (AKS) score] and complications were compared between the two groups. 【Results】 The operation time, time to get out of bed and full weight-bearing time of the observation group were shorter than those of the control group, and intraoperative blood loss was less (P<0.05). Postoperative knee swelling in the observation group was milder, and the maximum flexion and extension angles were larger than those in the control group (P<0.05). The knee score and function score of AKS in the observation group were higher than those in the control group (P<0.05). The total incidence of complications in the observation group was lower than that in the control group (P<0.05). 【Conclusions】 Arthroscopy-assisted minimally invasive reduction and internal fixation can reduce intraoperative blood loss and postoperative knee swelling, accelerate early functional recovery and improve knee joint function with fewer complications, which possesses high clinical application value for tibial plateau fractures. 2026 Vol. 43 (7): 1079-1082 [Abstract] ( 33 ) HTML (1 KB)  PDF (1198 KB)  ( 9 ) 1083 Effect of Nutritional Support Therapy Combined with Multilevel Health Education on Intervention in Patients with Pulmonary Tuberculosis Complicated with Diabetes Mellitus WEI Suxia, YANG Yuying, ZHANG Aihua DOI: 10.3969/j.issn.1671-7171.2026.07.008 【Objective】 To explore the intervention effect of nutritional support therapy combined with multi-level health education in patients with pulmonary tuberculosis and diabetes mellitus. 【Methods】 From June 2023 to June 2025, 90 patients with pulmonary tuberculosis complicated by diabetes mellitus who were treated in our hospital were selected and divided into the control group (using conventional intervention) and the observation group (using nutritional support therapy combined with multi-level health education), with 45 cases in each group. The nutritional status [albumin (ALB), hemoglobin (Hb)], blood glucose [fasting blood glucose (FPG), 2-hour postprandial blood glucose (2hPG)], tuberculosis-related stigma [score of the tuberculosis patient stigma scale (TSS)], and knowledge, attitude and behavior level [self-management knowledge, attitude and behavior (KAB) evaluation simplified scale (DSKAB-SF)] of the two groups were compared. 【Results】 After the intervention, the ALB and Hb levels of the observation group were higher than those of the control group (P<0.05), while the FPG and 2hPG levels were lower than those of the control group (P<0.05). The scores of each dimension of TSS in the observation group were lower than those of the control group (P<0.05), and the scores of each dimension of DSKAB-SF in the observation group were higher than those of the control group (P<0.05). 【Conclusion】 Nutritional support therapy combined with multi-level health education can improve the nutritional level of patients with pulmonary tuberculosis complicated by diabetes mellitus, lower blood glucose levels, reduce stigma, improve knowledge, attitude and behavior level, and promote the recovery of patients. 2026 Vol. 43 (7): 1083-1086 [Abstract] ( 34 ) HTML (1 KB)  PDF (1196 KB)  ( 17 ) 1087 Efficacy of Percutaneous Transluminal Carotid Angioplasty and Stenting in Treatment of Patients with Internal Carotid Artery Stenotic Cerebral Infarction WEI Liren DOI: 10.3969/j.issn.1671-7171.2026.07.009 【Objective】 To explore the efficacy of percutaneous transluminal carotid angioplasty and stenting (PTCAS) in the treatment of patients with internal carotid artery stenotic cerebral infarction. 【Methods】 A total of 100 patients with internal carotid artery stenotic cerebral infarction admitted from June 2023 to June 2025 were randomly divided into the control group and the observation group, with 50 cases in each group. The control group received simple carotid artery stenting, while the observation group was treated with PTCAS. Perioperative indicators, hemorheological parameters including fibrinogen (FIB), platelet aggregation rate (PAgT) and hematocrit (HCT), serological indicators including malondialdehyde (MDA), N-terminal pro-B-type natriuretic peptide (NT-proBNP) and osteopontin (OPN), neurological function assessed by National Institutes of Health Stroke Scale (NIHSS), activity of daily living evaluated by Barthel Index (BI), and the incidence of complications were compared between the two groups before and after treatment. 【Results】 The operation time of the observation group was longer than that of the control group, while the time to get out of bed and hospital stay were shorter than those of the control group (all P<0.05). After treatment, the levels of FIB, PAgT, HCT, MDA, NT-proBNP and OPN in the observation group were significantly lower than those in the control group (P<0.05). The NIHSS score of the observation group was lower, the BI score was higher, and the total incidence of complications was lower compared to the control group (P<0.05). 【Conclusion】 For patients with internal carotid artery stenotic cerebral infarction, PTCAS can reduce the incidence of complications, improve hemorheological indexes, promote the recovery of neurological function, and enhance patients' quality of life. 2026 Vol. 43 (7): 1087-1089 [Abstract] ( 34 ) HTML (1 KB)  PDF (1240 KB)  ( 6 ) 1090 Clinical Efficacy of Nebulized Acetylcysteine Combined with Bi-Level Positive Airway Pressure Ventilation in Patients with Acute Respiratory Distress Syndrome LIU Qiuhong, LI Chen, LIANG Xiacun, ZHOU Jinqiao DOI: 10.3969/j.issn.1671-7171.2026.07.010 【Objective】 To investigate the clinical efficacy of nebulized acetylcysteine combined with bi-level positive airway pressure (BiPAP) ventilation in the treatment of patients with acute respiratory distress syndrome (ARDS). 【Methods】 A total of 80 ARDS patients admitted to our hospital from January 2020 to July 2024 were enrolled and divided into the observation group (n=41) and the control group (n=39) according to different therapeutic regimens. The control group received BiPAP ventilation alone, while the observation group was given additional nebulized acetylcysteine on the basis of BiPAP treatment. The therapeutic effects of the two groups were compared. 【Results】 The total effective rate of the observation group was significantly higher than that of the control group (P<0.05). After 14 days of treatment, the levels of arterial partial pressure of oxygen (PaO2) and superoxide dismutase (SOD) in the observation group were higher, while malondialdehyde (MDA), arterial partial pressure of carbon dioxide (PaCO2) and fraction of inspired oxygen (FiO2) were lower than those of the control group (P<0.05). After 14 days of treatment, forced expiratory volume in the first second (FEV1), maximal voluntary ventilation (MMV) and FEV1/forced vital capacity (FEV1/FVC) of the observation group were superior to the control group (P<0.05). The levels of CD4+ and CD4+/CD8+ in the observation group were higher, and CD8+ was lower than the control group after 14 days (P<0.05). There was no statistically significant difference in the total incidence of adverse reactions between the two groups (P>0.05). 【Conclusions】 Nebulized acetylcysteine combined with BiPAP ventilation can improve pulmonary function and immune function in ARDS patients without increasing the risk of adverse reactions. 2026 Vol. 43 (7): 1090-1093 [Abstract] ( 30 ) HTML (1 KB)  PDF (1203 KB)  ( 4 ) 1094 Comparative Study on Diagnostic Value and Radiation Dose of Tomosynthesis versus Full Digital Radiography in Radial Head Fracture BA Jiwei, WANG Huaixin, YANG Xiaohua, ZHANG Xiaojing DOI: 10.3969/j.issn.1671-7171.2026.07.011 【Objective】 To compare the diagnostic value and radiation dose of tomosynthesis and full digital radiography for the classification of radial head fractures. 【Methods】 The clinical data of 201 patients with radial head fractures treated in the two hospitals from February 2020 to February 2022 were retrospectively analyzed, with the final clinical diagnosis as the gold standard. Among them, there were 83 cases of Mason type Ⅰ fractures, 77 cases of Mason type Ⅱ fractures and 41 cases of Mason type Ⅲ fractures. All patients underwent tomosynthesis and full digital radiography. The two imaging modalities were compared in terms of fracture detection rate, diagnostic performance for radial head fracture classification, image quality of bone structure and surrounding soft tissues, as well as radiation exposure. 【Results】 Tomosynthesis achieved a significantly higher fracture detection rate than full digital radiography (P<0.05). The overall diagnostic sensitivity of tomosynthesis for radial head fractures was statistically superior to full digital radiography (P<0.05). For Mason type Ⅱ and Ⅲ fractures, tomosynthesis showed significantly higher diagnostic sensitivity (P<0.05). Tomosynthesis yielded a significantly higher excellent visualization rate of bone structures and a better excellent/good rate of surrounding soft tissues (P<0.05). In addition, tomosynthesis delivered significantly lower radiation dose than full digital radiography (P<0.05). 【Conclusions】 Compared with full digital radiography, tomosynthesis has higher diagnostic value for radial head fracture classification, and it can optimize image quality while reducing radiation exposure. 2026 Vol. 43 (7): 1094-1097 [Abstract] ( 29 ) HTML (1 KB)  PDF (1196 KB)  ( 33 ) 1098 Effects of Donepezil Combined with Citicoline on Cognitive Function, Inflammatory Factors, and Neurotrophic Factors in Patients with Vascular Dementia GUO Fangli, LI Jianbo, ZHANG Jundong DOI: 10.3969/j.issn.1671-7171.2026.07.012 【Objective】 To investigate the effects of donepezil combined with citicoline on cognitive function, inflammatory factors, and neurotrophic factor expression in patients with vascular dementia (VAD). 【Methods】 A total of 98 patients with VAD were randomly divided into a control group (treated with donepezil alone) and an observation group (treated with both donepezil and citicoline), with 49 patients in each group. Clinical efficacy between the two groups was compared. 【Results】 After treatment, levels of neuron-specific enolase and nerve growth factor were lower in the observation group than in the control group, while brain-derived neurotrophic factor was higher (P<0.05). Levels of C-reactive protein, tumor necrosis factor-alpha, and interleukin-6 in the observation group were significantly lower than those in the control group(P<0.05). The observation group showed a higher score of the Mini-Mental State Examination (MMSE) and a lower score of the Clinical Dementia Rating Scale-Sum of Boxes (CDR-SB) compared to the control group (P<0.05). Clinical efficacy in the observation group was significantly higher in the control group (P<0.05), while there was no statistically significant difference in the incidence of complications between the two groups (P>0.05). 【Conclusion】 Combined treatment with donepezil and citicoline shows significant efficacy and good safety in treating VAD. It effectively reduces inflammatory factor levels, improves neurotrophic factor expression, alleviates dementia severity, and promotes recovery of neurological function. 2026 Vol. 43 (7): 1098-1100 [Abstract] ( 26 ) HTML (1 KB)  PDF (1245 KB)  ( 16 ) 1101 Efficacy of Evolocumab Versus Ezetimibe in the Treatment of Elderly Patients with Coronary Heart Disease Complicated with Hyperlipidemia TANG Enming, TAO Lewei, CHEN Wenzhe DOI: 10.3969/j.issn.1671-7171.2026.07.013 【Objective】 To investigate the clinical efficacy of evolocumab and ezetimibe and their influences on blood lipid levels in elderly patients with coronary heart disease (CHD) combined with hyperlipidemia. 【Methods】 A total of 152 elderly patients with CHD and hyperlipidemia admitted to our hospital from March 2023 to February 2024 were enrolled and divided into observation group and control group by random number table, with 76 cases in each group. The control group received ezetimibe on the basis of routine treatment, while the observation group was additionally given evolocumab combined with ezetimibe. The clinical efficacy, carotid ultrasound indicators, incidence of adverse reactions and laboratory parameters including low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), triglyceride (TG), soluble intercellular adhesion molecule-1 (sICAM-1), N-terminal pro-brain natriuretic peptide (NT-proBNP) and homocysteine (Hcy), procalcitonin (PCT) were compared between the two groups. 【Results】 After treatment, the total effective rate of the observation group was 97.37% (74/76), which was higher than 88.16% (67/76) of the control group (P<0.05). The serum levels of LDL-C, TC, TG, sICAM-1, NT-proBNP, Hcy and PCT in both groups decreased after treatment, and the observation group showed significantly lower levels than the control group (P<0.05). Carotid intima-media thickness and plaque area were reduced, and the number of plaques decreased in both groups after treatment; the observation group had thinner intima-media thickness, smaller plaque area and fewer plaques compared with the control group (P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups (P>0.05). 【Conclusions】 Combined therapy of evolocumab and ezetimibe can effectively reduce blood lipid levels, improve vascular endothelial and cardiac function with favorable safety profile in elderly patients with coronary heart disease complicated with hyperlipidemia. 2026 Vol. 43 (7): 1101-1104 [Abstract] ( 25 ) HTML (1 KB)  PDF (1207 KB)  ( 4 ) 1105 Value of High-Frequency Ultrasound-Guided Core Needle Biopsy Combined with Tumor Markers in Diagnosing Benign and Malignant Breast Masses DONG Yan DOI: 10.3969/j.issn.1671-7171.2026.07.014 【Objective】 To evaluate the diagnostic value of high-frequency ultrasound-guided core needle biopsy combined with tumor marker testing for distinguishing benign from malignant breast masses. 【Methods】 A total of 98 patients with breast masses admitted to our hospital between January 2021 and June 2025 were enrolled. Among them, 51 patients diagnosed with breast cancer by postoperative pathological examination were assigned to the observation group, and 47 patients with benign breast lesions were assigned to the control group. All patients underwent high-frequency ultrasound-guided core needle biopsy and measurement of carbohydrate antigen 125 (CA125), carbohydrate antigen 15-3 (CA15-3), and alpha-fetoprotein (AFP) levels. The diagnostic performance of the combination of high-frequency ultrasound-guided core needle biopsy with CA125, CA15-3, and AFP was assessed using receiver operating characteristic (ROC) curves. 【Results】 High-frequency ultrasound-guided core needle biopsy revealed 47 cases of breast cancer and 44 cases of benign breast lesions. The levels of CA125, CA15-3, and AFP in the observation group were significantly lower than those in the control group (P<0.05). ROC curve analysis showed that the sensitivity and specificity of high-frequency ultrasound-guided core needle biopsy combined with detection of CA125, CA15-3, and AFP for diagnosing benign versus malignant breast masses were 94.1% and 97.9%, respectively, with an area under the ROC curve (AUC) of 0.982. 【Conclusion】 The combination of high-frequency ultrasound-guided core needle biopsy with CA125, CA15-3, and AFP testing significantly improves the sensitivity and specificity in diagnosing the nature of breast masses and holds substantial clinical value. 2026 Vol. 43 (7): 1105-1107 [Abstract] ( 24 ) HTML (1 KB)  PDF (1306 KB)  ( 5 ) 1108 Efficacy of Cardiac Exercise Rehabilitation Combined with Tolvaptan in Patients with Heart Failure HUANG Hui, YANG Shengyong DOI: 10.3969/j.issn.1671-7171.2026.07.015 【Objective】 To explore the clinical efficacy of cardiac exercise rehabilitation (CER) combined with tolvaptan in patients with heart failure (HF). 【Methods】 A total of 105 HF patients admitted to the Cardiac Rehabilitation Department of our hospital from February 2023 to October 2024 were selected and divided into three groups by random number table, with 35 cases in each group. Control group A received conventional anti-heart failure therapy plus CER intervention; Control group B received conventional anti-heart failure therapy plus tolvaptan intervention; Observation group received conventional anti-heart failure therapy combined with both CER and tolvaptan intervention. Cardiac function indicators [left ventricular ejection fraction (LVEF), New York Heart Association (NYHA) cardiac function classification, brain natriuretic peptide (BNP), N-terminal pro-brain natriuretic peptide (NT-proBNP)], pulmonary function indicators [forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), percutaneous arterial oxygen saturation (SpO2)], clinical symptoms [Medical Research Council (MRC) dyspnea scale score, 24-hour urine volume, 6-minute walking distance (6MWD)], biochemical indicators [serum sodium (Na+), serum potassium (K+), serum creatinine (SCr), blood urea nitrogen (BUN)] and the incidence of adverse cardiovascular events were compared among the three groups before and after treatment. 【Results】 After treatment, LVEF increased, NYHA classification, serum BNP and NT-proBNP levels decreased in all three groups, with statistically significant intergroup differences (P<0.05). FVC and SpO2 of the three groups were significantly improved compared with baseline, FEV1/FVC rose markedly (P<0.05); the improvement of FVC and SpO2 in observation group was superior to two control groups (P<0.05). The MRC scores of all groups declined, and observation group had lower scores than the two controls (P<0.05). The 24-hour urine volume of control group A and B decreased after treatment (P<0.05), while that of observation group increased and was significantly higher than the two controls (P<0.05). The 6MWD of observation group increased obviously and was longer than the two controls (P<0.05). Serum Na+ of all three groups elevated after treatment with significant intergroup differences (P<0.05). Serum SCr decreased in each group (P<0.05), without statistical difference between groups (P>0.05). BUN levels dropped in all groups and showed significant intergroup differences (P<0.05). There was no significant difference in the incidence of adverse cardiovascular events among three groups (P>0.05). 【Conclusions】 CER combined with tolvaptan can improve cardiac function, relieve clinical symptoms and optimize biochemical indicators in heart failure patients with favorable safety profile and reduced readmission rate. 2026 Vol. 43 (7): 1108-1112 [Abstract] ( 25 ) HTML (1 KB)  PDF (1232 KB)  ( 4 ) 1113 Value of Combined Detection of Epstein-Barr Virus Antibodies, EBV-DNA Load and Lymphocyte Subsets in the Diagnosis of Infectious Mononucleosis in Children CHEN Yaohua, YUAN Linchao, LI Lin DOI: 10.3969/j.issn.1671-7171.2026.07.016 【Objective】 To investigate the value of combined detection of Epstein-Barr virus (EBV) antibodies, EBV-DNA load, and lymphocyte subsets in the diagnosis of infectious mononucleosis (IM) in children. 【Methods】 A total of 82 children with IM admitted to our hospital were enrolled as the observation group, while 80 healthy children undergoing routine physical examinations during the same period were included as the control group. The levels of EBV antibodies, EBV-DNA load, and lymphocyte subsets were compared between the two groups. Receiver operating characteristic (ROC) curves were constructed to evaluate the diagnostic value of EBV antibodies, EBV-DNA load, and lymphocyte subsets, alone and in combination, for IM in children. 【Results】 The positive rates of EBV capsid antigen immunoglobulin G (EBV-CA-IgG), EBV capsid antigen immunoglobulin M (EBV-CA-IgM), and EBV-DNA load in the observation group were significantly higher than those in the control group (P<0.05). The levels of CD3+ and CD8+ cells were significantly higher, whereas CD4+ cells and the CD4+/CD8+ ratio were significantly lower in the observation group than in the control group (P<0.05). ROC analysis showed that the combined detection of EBV antibodies, EBV-DNA load, and lymphocyte subsets achieved a sensitivity of 93.9%, a specificity of 95.0%, and an area under the curve (AUC) of 0.985 for diagnosing IM in children. 【Conclusion】 Combined detection of EBV antibodies, EBV-DNA load, and lymphocyte subsets can improve the diagnostic accuracy of infectious mononucleosis in children and has high clinical application value. 2026 Vol. 43 (7): 1113-1115 [Abstract] ( 28 ) HTML (1 KB)  PDF (1324 KB)  ( 4 ) 1116 Application Value of Serum Amyloid A and Prealbumin in Evaluating Therapeutic Efficacy and Prognosis of Patients with Acute Respiratory Infection FAN Linpeng, LU Ling, GUO Yunbo DOI: 10.3969/j.issn.1671-7171.2026.07.017 【Objective】 To explore the application value of serum amyloid A (SAA) and prealbumin (PA) levels in evaluating therapeutic efficacy and prognosis of patients with acute respiratory infection (ARI). 【Methods】 A total of 500 patients with ARI treated in our hospital from February 2023 to February 2025 were retrospectively analyzed. According to pathogen test results, patients were divided into viral infection group (n=238) and bacterial infection group (n=262). Based on disease severity, they were classified into mild group (n=182), moderate group (n=149) and severe group (n=169). In accordance with clinical outcomes, patients were divided into good prognosis group (n=407) and poor prognosis group (n=93). The levels of SAA and PA in each group were detected and compared. Receiver operating characteristic (ROC) curve analysis was used to evaluate the predictive efficiency of SAA and PA for the severity of ARI. Logistic regression analysis was adopted to identify influencing factors of poor prognosis in ARI patients. 【Results】 The level of SAA in bacterial infection group was higher than that of viral infection group, while PA level was lower, with statistically significant differences (P<0.05). As the severity of ARI aggravated, SAA level increased progressively and PA level decreased gradually, and intergroup differences were statistically significant (P<0.05). ROC curve analysis showed that combined detection of SAA and PA exhibited superior predictive efficiency for ARI severity compared with single indicator (P<0.05). The proportions of patients with bacterial infection, severe illness and lower respiratory tract infection were higher in poor prognosis group (P<0.05). Inflammatory indicators including SAA and white blood cell (WBC) count, C-reactive protein (CRP) were significantly higher, while PA was markedly lower in poor prognosis group (all P<0.05). Infection type, disease severity, infection site, SAA level, PA level, WBC count and CRP were independent influencing factors for poor prognosis of ARI patients. 【Conclusions】 The changes of serum SAA and PA levels possess important clinical value in judging therapeutic efficacy and predicting prognosis of patients with acute respiratory infection. 2026 Vol. 43 (7): 1116-1119 [Abstract] ( 29 ) HTML (1 KB)  PDF (1279 KB)  ( 4 ) 1120 Efficacy of Neoadjuvant Chemotherapy Combined with Surgery in Patients with Resectable and Borderline Resectable Pancreatic Cancer JIANG Dongrong DOI: 10.3969/j.issn.1671-7171.2026.07.018 【Objective】 To investigate the clinical efficacy of neoadjuvant chemotherapy combined with surgery in patients with resectable and borderline resectable pancreatic cancer. 【Methods】 A total of 70 patients with pancreatic cancer were enrolled in this study. Thirty-five patients who underwent surgery alone were assigned to the control group, while 35 patients who received neoadjuvant chemotherapy followed by surgery were assigned to the observation group. Perioperative outcomes and survival rates at 1 and 3 years postoperatively were compared between the two groups. 【Results】 There were no statistically significant differences between the two groups in terms of perioperative indicators including tumor diameter, surgical procedure, operative time, postoperative hospital stay, and postoperative complications (P>0.05). The 1-year and 3-year postoperative survival rates in the observation group were significantly higher than those in the control group, and the overall survival time in the observation group was significantly longer than that in the control group (P<0.05). In addition, the overall metastasis rate and local recurrence rate after surgery in the observation group were significantly lower than those in the control group (P<0.05). 【Conclusion】 Neoadjuvant chemotherapy combined with surgery is safe and feasible for patients with resectable and borderline resectable pancreatic cancer and does not increase perioperative risks. Moreover, it can significantly improve postoperative survival rates, prolong survival time, and effectively reduce local recurrence and distant metastasis rates, demonstrating substantial clinical value. 2026 Vol. 43 (7): 1120-1122 [Abstract] ( 25 ) HTML (1 KB)  PDF (1311 KB)  ( 6 ) 1123 Clinical Efficacy of Guizhi Fuling Pills Combined with Compound Gossypol Acetate Tablets in the Treatment of Patients with Endometriosis ZHANG Xin, ZHU Yan, LU Gaochuan DOI: 10.3969/j.issn.1671-7171.2026.07.019 【Objective】 To explore the clinical efficacy of Guizhi Fuling Pills combined with compound gossypol acetate tablets in patients with endometriosis (EMT). 【Methods】 The clinical data of 109 patients with EMT admitted to The Eighth People's Hospital of Shanghai from March 2021 to October 2023 were retrospectively analyzed. Patients were divided into the observation group (n=55) and the control group (n=54) according to different therapeutic regimens. The control group was treated with compound gossypol acetate tablets alone, while the observation group received Guizhi Fuling Pills on the basis of the control group. Both groups were treated for 3 months. TCM syndrome scores, clinical efficacy, ovarian function indicators [estradiol (E2), follicle-stimulating hormone (FSH), luteinizing hormone (LH)], inflammation-related indicators [interleukin-1β (IL-1β), high mobility group box protein B1 (HMGB1), matrix metalloproteinase-9 (MMP-9), macrophage migration inhibitory factor (MIF)], fetal liver kinase-1 (Flk-1), vascular endothelial growth factor (VEGF) and incidence of adverse reactions were compared between the two groups. 【Results】 After treatment, the total TCM syndrome score, primary syndrome score and secondary syndrome score of the observation group were lower than those of the control group (P<0.05). The total effective rate of the observation group was higher than that of the control group (P<0.05). The serum levels of E2, FSH and LH in the observation group were significantly lower than those in the control group after treatment (P<0.05). The serum levels of IL-1β, HMGB1, MMP-9, MIF, Flk-1 and VEGF in the observation group were all lower than those in the control group after treatment (P<0.05). There was no statistically significant difference in the total incidence of adverse reactions between the two groups (P>0.05). 【Conclusions】 The combined regimen of Guizhi Fuling Pills and compound gossypol acetate tablets has definite therapeutic effects on EMT patients. It can improve ovarian and vascular endothelial function, alleviate inflammatory response, reduce the levels of Flk-1 and MMP-9, with favorable safety. 2026 Vol. 43 (7): 1123-1126 [Abstract] ( 31 ) HTML (1 KB)  PDF (1208 KB)  ( 4 ) 1127 Efficacy of Qingyi Decoction Combined with Ulinastatin and Somatostatin in the Treatment of Acute Pancreatitis FU Guifang, QIU Yazhan DOI: 10.3969/j.issn.1671-7171.2026.07.020 【Objective】 To investigate the clinical efficacy of Qingyi Decoction combined with ulinastatin and somatostatin for patients with acute pancreatitis. 【Methods】 A total of 76 patients with acute pancreatitis admitted to Xinxian People's Hospital from July 2022 to July 2024 were enrolled and divided into observation group and control group by random number table method, with 38 cases in each group. The control group received combined treatment of ulinastatin and somatostatin; on the basis of the control group, the observation group was additionally given Qingyi Decoction. Traditional Chinese medicine (TCM) symptom scores and laboratory indicators including C-reactive protein (CRP), procalcitonin (PCT), interleukin-6 (IL-6), gastric inhibitory polypeptide (GIP), vasoactive intestinal peptide (VIP), lipase and amylase, as well as overall clinical efficacy were compared between the two groups before and after treatment. 【Results】 After treatment, the scores of TCM symptom scores in both groups were lower than those before treatment, and the observation group had lower scores than the control group (P<0.05). The serum levels of CRP, PCT, IL-6, amylase, lipase, GIP and VIP in both groups decreased after treatment, with significantly lower levels in the observation group compared with the control group (P<0.05). The total clinical effective rate of the observation group was higher than that of the control group (P<0.05). 【Conclusions】 Qingyi Decoction combined with ulinastatin and somatostatin can significantly relieve clinical symptoms, improve pancreatic function indicators and suppress inflammatory response in patients with acute pancreatitis, with superior therapeutic effect to single western medicine regimen. 2026 Vol. 43 (7): 1127-1129 [Abstract] ( 25 ) HTML (1 KB)  PDF (1241 KB)  ( 7 ) 1130 Effect of Qufeng Juanyin Decoction on Pulmonary Function and Inflammatory Factors in Children with Bronchial Asthma XIAO Yanshan DOI: 10.3969/j.issn.1671-7171.2026.07.021 【Objective】 To investigate the effects of Qufeng Juanyin Decoction on pulmonary function and inflammatory factors in children with bronchial asthma. 【Methods】 A total of 120 children diagnosed with bronchial asthma from January 2022 to January 2024 were selected as study subjects and randomly divided into an observation group and a control group (with 60 cases in each group) using a random number table method. The control group received treatment with fluticasone propionate inhaler combined with oral pediatric lung cough granules, while the observation group received the same regimen plus Qufeng Juanyin Decoction. Clinical efficacy, symptom resolution time, overall adverse reaction rate, and changes in pulmonary function indicators (peak expiratory flow, PEF; forced expiratory volume in one second, FEV1; FEV1/forced vital capacity, FVC), as well as levels of inflammatory factors [eosinophils(EOS); interleukin-6(IL-6); interleukin-17(IL-17); interleukin-22(IL-22)] before and after treatment, were compared between the two groups. 【Results】 The overall control rate in the observation group was significantly higher than that in the control group (P<0.05). After treatment, the observation group showed shorter durations for symptom resolution including cough, dyspnea, and wheezing compared to the control group (P<0.05). Additionally, PEF, FEV1, and FEV1/FVC values in the observation group were higher (P<0.05), while EOS, IL-6, IL-17, and IL-22 levels in the observation group were lower (P<0.05)than those in the control group. There was no statistically significant difference in the overall incidence of adverse reactions between the two groups (P>0.05). 【Conclusion】 Adding Qufeng Juanyin Decoction in addition to conventional therapy significantly improves clinical outcomes in children with bronchial asthma, effectively alleviates symptoms such as shortness of breath and coughing, enhances pulmonary function, reduces inflammation, and demonstrates high safety, making it worthy of clinical application and promotion. 2026 Vol. 43 (7): 1130-1133 [Abstract] ( 46 ) HTML (1 KB)  PDF (1202 KB)  ( 7 ) 1134 Application Effect of Dexmedetomidine Combined with Fentanyl in Comfort-Oriented Dental Implant Surgery WU Junli, FAN Duanyang DOI: 10.3969/j.issn.1671-7171.2026.07.022 【Objective】 To investigate the clinical efficacy of dexmedetomidine (Dex) combined with fentanyl anesthesia in comfort-oriented dental implant surgery. 【Methods】 A total of 60 patients undergoing dental implant surgery were randomly assigned to a control group and an observation group, with 30 patients in each group. Patients in the control group received the conventional anesthesia regimen, while those in the observation group received dexmedetomidine combined with fentanyl in addition to the conventional regimen. Perioperative indicators, analgesic efficacy, patient and physician satisfaction, and the incidence of adverse reactions were compared between the two groups. 【Results】 The anesthesia duration and post-anesthesia care unit (PACU) observation time were significantly longer in the observation group than in the control group(P<0.05), and the Ramsay sedation score was significantly higher in the observation group (P<0.05). The postoperative 2-hour Numeric Rating Scale (NRS) pain score was significantly lower in the observation group than in the control group(P<0.05). Both patient satisfaction and physician satisfaction scores in the observation group were significantly higher than those in the control group (P<0.05). There was no statistically significant difference in the overall incidence of adverse reactions between the two groups (P>0.05). 【Conclusion】 Dexmedetomidine combined with fentanyl can significantly improve the sedative and analgesic effects in patients undergoing comfort-oriented dental implant surgery, with a favorable safety profile. 2026 Vol. 43 (7): 1134-1136 [Abstract] ( 24 ) HTML (1 KB)  PDF (1175 KB)  ( 9 ) 1137 Diagnostic Value of hs-CRP Combined with NLR for Urosepsis after Urinary Calculus Surgery LUO Rongtuan, YU Quanfeng, GAO Ke DOI: 10.3969/j.issn.1671-7171.2026.07.023 【Objective】 To investigate the diagnostic value of high-sensitivity C-reactive protein (hs-CRP) combined with neutrophil-to-lymphocyte ratio (NLR) for urosepsis in patients after urinary calculus surgery. 【Methods】 A total of 80 patients who underwent urinary calculus surgery in our hospital from October 2020 to December 2024 were enrolled. According to the postoperative diagnosis of urosepsis, the patients were divided into sepsis group (n=26) and non-sepsis group (n=54). The baseline data, hs-CRP and NLR levels were compared between the two groups. Univariate and multivariate Logistic regression analyses were used to analyze the related factors of postoperative urosepsis. Receiver operating characteristic (ROC) curves were plotted to analyze the diagnostic efficacy of hs-CRP, NLR alone and their combination. 【Results】 There were statistically significant differences in gender, surgical approach, stone diameter, positive urine culture, operation time, NLR and hs-CRP levels between the two groups (P<0.05). Multivariate Logistic regression analysis showed that NLR, hs-CRP, surgical approach and positive urine culture were influencing factors of postoperative urosepsis (P<0.05). ROC curve analysis showed that the area under curve (AUC), sensitivity and specificity of hs-CRP were 0.937, 92.3% and 84.9% respectively; those of NLR were 0.876, 92.3% and 71.9% respectively; the combined detection achieved an AUC of 0.952, sensitivity of 92.3% and specificity of 90.4%. 【Conclusions】 Combined detection of hs-CRP and NLR has high diagnostic value for urosepsis after urinary calculus surgery, which can be used as effective indicators for early clinical identification of this complication. 2026 Vol. 43 (7): 1137-1139 [Abstract] ( 26 ) HTML (1 KB)  PDF (1302 KB)  ( 6 ) 1140 Efficacy of Huopu Xialing Decoction Combined with Tiaojing Decoction in the Treatment of Patients with Polycystic Ovary Syndrome of Kidney Deficiency and Phlegm-Dampness Type LI Yanling DOI: 10.3969/j.issn.1671-7171.2026.07.024 【Objective】 To evaluate the clinical efficacy of Huopu Xialing Decoction combined with Diaojing Decoction in treating patients with polycystic ovary syndrome (PCOS) of the kidney deficiency and phlegm-damp type. 【Methods】 A retrospective analysis was conducted on clinical data from 97 patients with PCOS of the kidney deficiency and phlegm-damp type who were admitted to our hospital between June 2022 and June 2023. Patients were divided into a control group (treated with drospirenone-ethinyl estradiol tablets, n=49) and an observation group (treated with the same medication plus Huopu Xialing Decoction combined with Diaojing Decoction, n=48). The therapeutic effects, TCM syndrome scores, menstrual recovery, gynecological ultrasound indicators, sex hormone levels, and adverse reactions were compared between the two groups. 【Results】 The therapeutic effect in the observation group was superior to that in the control group (P<0.05). After treatment, the TCM syndrome scores for main and secondary symptoms, visual analog scale (VAS) scores for dysmenorrhea, and endometrial thickness were all lower in the observation group than in the control group. While resistance index (RI) and follicle diameter were higher, and menstrual cycle length was shorter in the observation group than in the control group. The differences were statistically significant (P<0.05). Post-treatment, follicle-stimulating hormone (FSH) level was higher in the observation group, while testosterone and luteinizing hormone (LH) levels were lower compared to the control group, with statistically significant differences (P<0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05). 【Conclusion】 Huopu Xialing Decoction combined with Diaojing Decoction is effective in improving TCM syndrome, menstrual cycle, and endometrial thickness, while reducing testosterone and LH levels, thereby enhancing therapeutic outcomes with high safety. 2026 Vol. 43 (7): 1140-1143 [Abstract] ( 30 ) HTML (1 KB)  PDF (1204 KB)  ( 9 ) 1144 Diagnostic Value of Related Parameters of Three-Dimensional Arterial Spin Labeling Imaging for Cognitive Dysfunction in Patients with Ischemic Leukoaraiosis TONG Xiangsha, ZHAN Haohui, HU Gefan DOI: 10.3969/j.issn.1671-7171.2026.07.025 【Objective】 To investigate the diagnostic value of three-dimensional arterial spin labeling (3D-ASL) for cognitive dysfunction in patients with ischemic leukoaraiosis (ILA). 【Methods】 According to the Montreal Cognitive Assessment (MoCA) scores, 85 patients with ILA were divided into a cognitive dysfunction group (Group A, n=30) and a normal cognitive function group (Group B, n=55).3D-ASL was performed to obtain cerebral blood flow (CBF) values in whole-brain regions of interest (ROIs). Multivariate logistic regression analysis was used to identify factors associated with cognitive dysfunction in patients with ILA. Receiver operating characteristic (ROC) curve analysis was conducted to evaluate the diagnostic performance for cognitive dysfunction in ILA patients. 【Results】 Compared with Group B, Group A had significantly higher age, proportion of grade 3 ILA, homocysteine (Hcy), and fibrinogen (FIB) levels, while C-reactive protein (CRP) levels and CBF values in the whole brain, periventricular region, and subcortical region were significantly lower (all P<0.05). Multivariate logistic regression analysis showed that age, ILA grade, Hcy, and FIB were risk factors for cognitive dysfunction in patients with ILA (P<0.05), whereas CRP and CBF values in the whole brain, periventricular region, and subcortical region were protective factors (P<0.05). ROC curve analysis demonstrated that the combined detection of whole-brain, periventricular, and subcortical CBF values yielded an area under the curve (AUC) of 0.959, with significantly better diagnostic performance than any single indicator alone. 【Conclusion】 Age, ILA grade, Hcy, FIB, CRP, and CBF levels are important factors affecting cognitive function in patients with ILA. The combined assessment of CBF values in the whole brain, periventricular region, and subcortical region provides higher diagnostic value for cognitive dysfunction in patients with ILA. 2026 Vol. 43 (7): 1144-1147 [Abstract] ( 25 ) HTML (1 KB)  PDF (1285 KB)  ( 4 ) 1148 Correlation between Carotid Ultrasound Parameters, Relative Expression of Plasma miR-146a and miR-214 and Coronary Heart Disease in Patients with Hyperlipidemia MA Liping, CHEN Jing, ZHAO Wei DOI: 10.3969/j.issn.1671-7171.2026.07.026 【Objective】 To explore the correlation between carotid ultrasound parameters, relative expression levels of plasma miR-146a, miR-214 and coronary heart disease (CHD) in patients with hyperlipidemia. 【Methods】 A total of 90 hyperlipidemic patients with suspected high risk of CHD admitted to the two hospitals from July 2022 to July 2024 were enrolled. According to coronary angiography results, patients were divided into observation group (complicated with CHD, n=68) and control group (without CHD, n=22). General data, laboratory indicators including triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), miR-146 and miR-214, as well as carotid ultrasound parameters including intima-media thickness (IMT), and carotid Crouse plaque score ambulatory arterial stiffness index (AASI) were compared between the two groups. Influencing factors for CHD in hyperlipidemic patients were analyzed, and a prediction model based on carotid ultrasound indicators and plasma miR-146a, miR-214 expression was constructed and verified. 【Results】 There was no significant difference in TG and HDL-C levels between the two groups (P>0.05). TC, IMT, AASI, carotid Crouse plaque score, miR-146a and miR-214 in the observation group were significantly higher than those in the control group (P<0.05). Logistic regression analysis showed that TC (OR=4.483), IMT(OR=19.739), AASI (OR=2.854), carotid Crouse plaque score (OR=4.999), miR-146a (OR=12.849) and miR-214 (OR=3.438) were risk factors for CHD in hyperlipidemic patients (P<0.05). ROC curve analysis demonstrated that the combined model had a sensitivity of 0.868, specificity of 0.955 and AUC of 0.964 for predicting CHD. 【Conclusions】 Carotid ultrasound parameters and relative expression of plasma miR-146a, miR-214 are correlated with the occurrence of CHD in hyperlipidemic patients. The established comprehensive prediction model has favorable predictive efficiency and can assist in evaluating the risk of CHD. 2026 Vol. 43 (7): 1148-1151 [Abstract] ( 27 ) HTML (1 KB)  PDF (1451 KB)  ( 8 ) 1152 Experience Summary of Ureteroscopic Holmium Laser Lithotripsy under Local Anesthesia for Ureteral Calculi HE Yujie, PENG Yang, WANG Ziming, ZHANG Dingrong, REN Lin, ZENG Zhiheng, LI Hao, YU Bin, WANG Huan DOI: 10.3969/j.issn.1671-7171.2026.07.027 【Objective】 To explore the feasibility and safety of ureteroscopic holmium laser lithotripsy (URSL) under local anesthesia in the treatment of ureteral calculi. 【Methods】 The clinical data of 52 patients with ureteral calculi who received URSL under local anesthesia in The Third People’s Hospital of Hunan Province from January 2023 to September 2025 were retrospectively analyzed. Perioperative indicators, surgical outcomes, postoperative complications and patient satisfaction were compared. 【Results】 The average stone diameter of the 52 patients was (7.12±3.36) mm. All operations were completed under local anesthesia, including 42 cases of rigid ureteroscopic holmium laser lithotripsy and 10 cases of flexible ureteroscopic holmium laser lithotripsy. The mean operative time was (13.27±6.17) min; the operative time of male patients [(19.71±6.52) min] was significantly longer than that of female patients [(11.13±5.01) min] (P<0.05). The average intraoperative VAS score was (2.67±2.89) points, and the mean intraoperative VAS score of males [(5.50±1.50) points] was higher than that of females [(1.66±1.99) points] (P<0.05). The incidence of moderate to severe intraoperative pain in males was 72.22% (13/18), which was higher than 23.53% (8/34) in females (P<0.05). No severe intraoperative or postoperative complications occurred, and the early stone clearance rate reached 100%. The average satisfaction score of female patients was statistically higher than that of males (P<0.05). 【Conclusions】 URSL under local anesthesia is safe and efficient for ureteral calculi, especially suitable for mid and distal ureteral stones. Benefiting from anatomical advantages, female patients experience milder pain and shorter operation time with higher satisfaction, and can be taken as the priority recommended population. 2026 Vol. 43 (7): 1152-1155 [Abstract] ( 30 ) HTML (1 KB)  PDF (1206 KB)  ( 25 ) 1156 Comparison of Application Effects between Transradial and Transfemoral Approaches in Digital Subtraction Angiography and Cerebral Artery Stenting ZHANG Na DOI: 10.3969/j.issn.1671-7171.2026.07.028 【Objective】 To compare the clinical effects of transradial and transfemoral approaches in digital subtraction angiography (DSA) and cerebral artery stenting. 【Methods】 A total of 118 patients who underwent cerebral DSA and cerebral artery stenting in our hospital from March 2023 to March 2024 were enrolled and divided into the observation group (61 cases, transradial approach) and the control group (57 cases, transfemoral approach) according to different access routes. Operation time, puncture time, postoperative recovery time, contrast medium dosage, fluoroscopy time, success rates of puncture and cerebral angiography, image acquisition parameters and incidence of complications were compared between the two groups. 【Results】 There was no significant difference in contrast medium dosage between the two groups (P>0.05). The observation group had shorter operation time, puncture time and postoperative recovery time but longer fluoroscopy time than the control group (P<0.05). The success rate of cerebral angiography was higher while the puncture success rate was lower in the observation group (P<0.05). No statistically significant differences were found in CD, DAP, cine DAP, fluoroscopic DAP and frame number between two groups (P>0.05). The incidence of complications in the observation group was significantly lower than that of the control group (P<0.05). 【Conclusions】 Compared with the transfemoral approach, the transradial approach has no obvious influence on the dosage of contrast medium. It can shorten operation, puncture and postoperative recovery time, achieve higher angiography success rate and lower complication risk. 2026 Vol. 43 (7): 1156-1159 [Abstract] ( 27 ) HTML (1 KB)  PDF (1231 KB)  ( 4 )

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