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Predictive Value of PLR Combined with CHA2DS2-VASc Score for No-Reflow Phenomenon after PCI in STEMI Patients |
TAO Shoujian, JIA Bei |
Department of Clinical Laboratory, Xinyang Central Hospital,Xinyang Henan 464000 |
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Abstract 【Objective】 To explore the predictive value of the platelet-to-lymphocyte ratio (PLR) combined with the CHA2DS2-VASc score for the no-reflow phenomenon after percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI).【Methods】A total of 136 STEMI patients who underwent PCI were analyzed. According to the occurrence of the no-reflow phenomenon postoperatively, the patients were divided into groups. Binary logistic regression analysis was used to identify the influencing factors of reflow or no-reflow after PCI. Receiver operating characteristic (ROC) curve analysis was performed to assess the predictive value of PLR and CHA2DS2-VASc score for postoperative no-reflow.【Results】 Among the 136 patients, 31 cases (21.23%) developed the no-reflow phenomenon after PCI (no-reflow group), while the remaining 105 cases did not (reflow group). Preoperative systolic and diastolic blood pressure, interleukin-6, total stent length, PLR, and CHA2DS2-VASc score were all significantly higher in the no-reflow group compared to the reflow group (P<0.05). Logistic regression analysis showed that total stent length, PLR, and CHA2DS2-VASc score were risk factors for postoperative no-reflow. ROC curve analysis indicated that the combination of PLR and CHA2DS2-VASc score had a significantly higher area under the curve and specificity for predicting no-reflow after PCI compared to either parameter alone (P<0.05).【Conclusion】 The combination of PLR and CHA2DS2-VASc score has a high predictive value for the occurrence of no-reflow in STEMI patients after PCI and can serve as an important reference for evaluating postoperative no-reflow risk.
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Received: 14 September 2024
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