Abstract：【Objective】To investigate the clinical features of single umbilical artery (SUA) with cardiovascular malformations. 【Methods】A total of 112 fetuses with SUA were retrospectively analyzed. Clinical data and ultrasound images were collected to investigate complication with cardiovascular malformations and pregnancy outcomes. 【Results】Among the 112 SUA patients, simple SUA occurred in 80 cases(71.4%) and SUA complicated with other structural malformations were seen in 32 cases (28.6%),of which 25 cases(25/32,22.3%) were combined with cardiovascular malformations including 18 cases of severe complex malformations. No abnormal chromosome findings were shown in all 25 cases of SUA with cardiovascular malformations. However,20 cases were induced labor and 5 live births (2 cases of ventricular septal defect and 3 cases of ventricular septal defect with left superior vena cava were diagnosed by prenatal and postnatal ultrasound follow-up). The cardiovascular malformations in the top three places were ventricular septal defect (17/25, 68%), persistent left superior vena cava (6/25, 24%) and persistent arterial trunk (5/25, 20%). 【Conclusions】The most common malformations in SUA is cardiovascular malformation, which is so complicated types and poor prognosis. The diagnosis of fetal structural abnormalities during pregnancy, especially in the second trimester, is important for early intervention and reduction of birth defects.
李巧荣, 龙湘党, 姚穗, 王莉萍, 申建华, 郭叶青. 112例单脐动脉胎儿合并心血管畸形情况及其妊娠结局分析[J]. 医学临床研究, 2019, 36(10): 1881-1883.
LI Qiao-rong, LONG Xiang-dang, YAO Sui,et al. Analysis of Cardiovascular Malformations and Pregnancy Outcomes in 112 Fetuses of Single Umbilical Artery. JOURNAL OF CLINICAL RESEARCH, 2019, 36(10): 1881-1883.
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2019, Vol. 36 
