Abstract：【Objective】 To study the clinical value of five-transverse -section echocardiography ultrasound in fetal heart malformation screening.【Methods】Eight thousand one hundred and fifty-six cases of pregnant women in our hospital from January 2011 to June 2014 were selected as the research objects, the detection of five-transverse-section of the fetus heart (abdominal transverse section, heart four chamber view, left ventricular outflow tract, right ventricular outflow tract, three blood vessels - trachea view) was conducted to compare the results with those of the autopsy and the echocardiography of the newborn infants, and to analyze the abnormal karyotype . 【Results】 8,156 cases of pregnant women were successfully completed the heart five-transverse-section ultrasound examination; Congenital heart defects were detected in 43 cases, the detection rate was 0.53%; Autopsy or postnatal echocardiography of the newborn infants showed 5 cases of missed diagnosis and 3 cases of misdiagnosis, among which 2 cases of the inner cushion defect were misdiagnosed as simple ventricular septal defect(ASD), and 1 case of tetralogy of Fallot misdiagnosed as simple atrial septal defect (ASD). The specificity, sensitivity, negative predictive value and positive predictive value of the five -transverse-section Ultrasound heart examination were 99.96%(8088/8091), 88.89%(40/45), 99.93%(8088/8093) and 93.02%(40/43) respectively. Within 43 cases of fetal heart malformation, 19 cases performed chromosome karyotype examination, and abnormal karyotype was found in 9 cases.【Conclusion】 The routine prenatal heart five-transverse-section Ultrasound examination can be used to screen for fetal congenital cardiac malformation more accurately, and it is conducive to infer the fetal chromosomal abnormalities.
2016, Vol. 33 
