Abstract：【Objective】To explore the clinical value of two-dimensional combined with four-dimensional ultrasound in prenatal diagnosis of fetus congenital heart malformation.【Methods】From September 2011 to September 2015, 4642 cases of the middle and late pregnant women who received prenatal examination were randomly selected from in our hospital. Prenatal examination of pregnant women was performed by two-dimensional ultrasound at first, then, the fetuses with suspected malformation under two-dimensional ultrasound were examined by four-dimensional ultrasonography again. By analyzing and comparing the two methods of two-dimensional ultrasound and two-dimensional combined with four-dimensional ultrasound, the clinical value of the two methods was determined by the different accuracy of fetal malformation diagnosis.【Results】By follow-up, congenital heart malformations were found in 89 fetuses out of 4681 fetuses, the incidence rate was 1.9%. In 89 fetal malformations, 70 fetuses with congenital heart malformations were examined by two-dimensional ultrasound. Among them, 16 cases were missed or misdiagnosed; a total of 78 fetuses with congenital heart malformations were examined by two-dimensional ultrasound combined with four-dimensional ultrasound, and 11 cases were missed or misdiagnosed. The diagnostic accuracy of two-dimensional ultrasound combined with four-dimensional ultrasonography was significantly higher than that of two-dimensional ultrasound (P<0.05) .【Conclusion】Ultrasonography is an effective method for prenatal diagnosis of fetal congenital heart malformations. Four dimensional ultrasonography can be a useful supplement to two-dimensional ultrasound. Combination of two kinds of ultrasound examination can significantly improve the accuracy of diagnosis of fetal congenital heart malformations, and effectively reduce the incidence of misdiagnosis and leakage.
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2017, Vol. 34 
