揿针埋植联合黄连温胆汤加减方治疗女性更年期综合征合并睡眠障碍患者的疗效

doi:10.3969/j.issn.1671-7171.2025.01.031

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摘要【目的】探讨揿针埋植联合黄连温胆汤加减方治疗女性更年期综合征(CMS)合并睡眠障碍患者的疗效。【方法】96例女性CMS合并睡眠障碍患者,随机分为对照组和观察组,每组48例。对照组口服艾司唑仑治疗,观察组采用揿针埋植联合黄连温胆汤加减方治疗。比较两组临床疗效、治疗前后血清激素[雌二醇(E₂)、卵泡刺激素(FSH)、黄体生成素(LH)]水平、中医证候积分及睡眠质量[匹兹堡睡眠质量指数量表(PSQI)]评分。【结果】治疗后,两组患者中医证候积分、FSH水平及PSQI评分低于治疗前(P<0.05),E₂水平高于治疗前(P<0.05);观察组总有效率及E₂水平高于对照组,中医证候积分、FSH水平及PSQI评分低于对照组(P<0.05)。【结论】揿针埋植联合黄连温胆汤加减方治疗可显著提高女性CMS合并睡眠障碍患者的疗效及E₂水平,同时降低中医证候积分、血清FSH水平及PSQI评分,其临床疗效优于艾司唑仑。

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	张丽敏
	刘敏
	朱培育

关键词 ：更年期综合征, 睡眠障碍, 黄连温胆汤, 针刺疗法

Abstract：【Objective】 To explore the efficacy of auricular acupoint pressing(press-needle implantation) combined with a modified Huanglian Wendan Decoction in treating female patients with climacteric syndrome (CMS) accompanied by sleep disorders.【Methods】Ninety-six female patients with CMS and sleep disorders were randomly divided into a control group and an observation group, with 48 patients in each group. The control group was treated with oral estazolam, while the observation group received auricular acupoint pressing(press-needle implantation) combined with a modified Huanglian Wendan Decoction. Clinical efficacy, serum hormone levels [estradiol (E₂), follicle-stimulating hormone (FSH), luteinizing hormone (LH)], Traditional Chinese Medicine (TCM) syndrome scores, and sleep quality [Pittsburgh Sleep Quality Index (PSQI)] were compared between the two groups before and after treatment.【Results】 After treatment, the TCM syndrome scores, FSH levels, and PSQI scores of both groups were lower than before treatment (P<0.05), and E₂ levels were higher than before treatment (P<0.05). The total effective rate and E₂ levels in the observation group were higher than those in the control group, while TCM syndrome scores, FSH levels, and PSQI scores were lower than those in the control group (P<0.05).【Conclusion】 Auricular acupoint pressing combined with a modified Huanglian Wendan Decoction can significantly improve the efficacy and E₂ levels in female patients with CMS and sleep disorders, while reducing TCM syndrome scores, serum FSH levels, and PSQI scores. Its clinical efficacy is superior to that of estazolam.

Key words： Climacteric Syndrome Sleep Disorders Huanglian Wendantang Acupuncture Therapy

收稿日期: 2024-04-18

中图分类号:

R271.116

引用本文:

张丽敏, 刘敏, 朱培育. 揿针埋植联合黄连温胆汤加减方治疗女性更年期综合征合并睡眠障碍患者的疗效[J]. 医学临床研究, 2025, 42(1): 109-111.
ZHANG Limin, LIU Min, ZHU Peiyu. Efficacy of Auricular Acupoint Pressing Combined with Modified Huanglian Wendan Decoction in Treating Female Climacteric Syndrome with Sleep Disorders. JOURNAL OF CLINICAL RESEARCH, 2025, 42(1): 109-111.

链接本文:

http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2025.01.031 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2025/V42/I1/109