Abstract：【Objective】To analyze the sleep disorder and its influencing factors in elderly patients with type 2 diabetes mellitus (T2DM) and osteoporosis (OP). 【Methods】A total of 136 elderly patients with T2DM and OP from January 2016 to February 2018 were enrolled for the study as OP group. 150 elderly T2DM patients without OP were randomly selected as non-OP group and 100 healthy elderly during the same period were randomly selected as control group. The score of Pittsburgh Sleep Inventory Index (PSQI) were compared among three groups, and the relationship between clinical data and sleep disorder were analyzed in the three groups. 【Results】The scores and total scores of PSQI in the OP group and the NOP group were significantly higher than those in the CN group. The scores and total scores of subjective sleep disorder, sleep quality and sleep efficiency in the OP group were significantly higher than those in the NOP group (P<0.05). The incidence of sleep disorder in the OP group was 74.3% (101/136), significantly higher than that in the NOP group and the CN group (60.7%,35.0%) (P<0.05). In the OP group, the incidence of sleep disorders in patients with age ≤70 years, divorce or widowhood, duration of T2DM > 15 years, HbA1c > 9.0%, diabetic neuropathy, insulin use, pain sites (≥3), moderate and severe pain, muscle spasm, spinal deformity, severe OP and other patients increased significantly, while the incidence of sleep disorders in patients treated with anti-OP decreased significantly (P<0.05). Multivariate logistic regression analysis showed that the duration of T2DM>15 years, HbA1c > 9.0%, moderate to severe pain and severe OP were independent risk factors for sleep disorders (P<0.05). 【Conclusion】The sleep status of elderly patients with T2DM and OP is poor, about 3/4 of them have sleep disorders. The duration of T2DM>15 years, HbA1c>9.0%, moderate and severe pain and severe OP are independent risk factors for sleep disorders in elderly patients with T2DM and OP.
张红敏, 杨媚, 唐颖, 刘勋, 周唯妮, 张兴渝, 乐曦. 老年2型糖尿病伴骨质疏松患者的睡眠质量及其影响因素[J]. 医学临床研究, 2019, 36(3): 426-429.
ZHANG Hong-min, YANG Mei, TANG Ying, et al. Analysis of Sleep Quality and its Influencing Factors in Elderly Patients with Type 2 Diabetes Mellitus and Osteoporosis. JOURNAL OF CLINICAL RESEARCH, 2019, 36(3): 426-429.
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2019, Vol. 36 
