Abstract：【Objective】To explore the role of transendoscopic microprobe ultrasound(MPS) in the classification and diagnosis of inflammatory bowel disease(IBD). 【Methods】 A total of 84 patients with IBD admitted to Meixian People's Hospital from March 2017 to March 2020 were selected as the observation group,including 58 cases of ulcerative colitis(UC)(UC group) and 26 cases of Crohn's disease(CD)(CD group). Another 84 healthy individuals who underwent physical examination during the same period were selected as the control group.All subjects underwent transendoscopic MPS examination,recorded the endoscopic characteristics of IBD,and analyzed the clinical value of MPS in differential diagnosis of IBD.【Results】 The MPS findings of UC patients under endoscopy showed a continuous distribution of mucosal lesions,with a higher incidence of "fish mouth" lesions than CD,and a lower incidence of "ear-like" lesions than CD,with significant statistical differences(P<0.05). The Kappa values of MPS for Tsuga classification and modified Baron classification in UC patients were 0.720 and 0.815,respectively,while the Kappa value for Montreal disease behavior classification in CD patients was 0.716.The comparison of total wall thickness(TWT),muscularis propria(MP),submucosa(SM),and mucosa(M) levels among the three groups showed significant statistical differences(P<0.05). The receiver operating characteristic(ROC) curve analysis showed that the AUC value of M value for UC was 0.753(95%CI=0.641-0.864,P<0.001),with a sensitivity of 0.862 and a specificity of 0.691.The AUC value of MP value for CD was 0.759(95%CI=0.592-0.926,P=0.003).【Conclusion】Transendoscopic MPS for IBD examination is helpful for the classification and diagnosis of CD and UC,which is of great value in guiding early intervention for IBD patients.
王素玲, 贾红娥, 邓召亮. 经肠镜微探头超声在炎症性肠病分型诊断中的应用价值[J]. 医学临床研究, 2023, 40(11): 1720-1722.
WANG Suling, JIA Honge, DEGN Zhaoliang. Clinical Value of Transendoscopic Microprobe Ultrasound in the Diagnosis of Inflammatory Bowel Disease. JOURNAL OF CLINICAL RESEARCH, 2023, 40(11): 1720-1722.
2023, Vol. 40 
