Effect of Botulinum Toxin Type A Combined with Routine Rehabilitation on Balance Ability and Daily Living Ability of Children with Spastic Hemiplegic Cerebral Palsy
Abstract：【Objective】To investigate the effect of botulinum toxin a combined with routine rehabilitation therapy on balance ability and daily living ability of children with spastic hemiplegic cerebral palsy. 【Methods】A total of 57 children with spastic hemiplegia treated in the rehabilitation center of Hunan children's Hospital from January 2017 to June 2020, including 38 males and 19 females, was divided into control group (n=26, given routine rehabilitation treatment) and observation group (n=31, injected with botulinum toxin a combined with routine rehabilitation treatment) according to the wishes of their families. The children in the two groups were treated for 3 months. The spasticity degree, balance ability and quality of life of the two groups were evaluated by comprehensive spasticity scale (CCS), Berg Balance Scale (BBS) and modified Barthel index scale before and after treatment. 【Results】 Before treatment, there was no significant difference between the two groups (P>0.05); After treatment, the scores of comprehensive spasm scale in the two groups were lower than those before treatment, and the observation group was lower than that in the control group, the difference was statistically significant (mean P<0.05). Before treatment, there was no significant difference in Berg Balance Scale score and ADL score between the two groups (P>0.05); After treatment, the Berg Balance Scale score and ADL score of the two groups were higher than those before treatment, and the observation group was higher than that of the control group, the difference was statistically significant (mean P<0.05). 【Conclusion】 Botulinum toxin a combined with routine rehabilitation treatment for children with spastic hemiplegic cerebral palsy can significantly improve the balance function and daily living ability of children with spastic hemiplegic cerebral palsy, with high safety, which can be popularized in clinic.
袁丽平, 何金华, 胡继红, 刘华, 段雅琴, 王益梅. A型肉毒毒素联合常规康复治疗对脑瘫所致痉挛型偏瘫患儿平衡能力及日常生活能力的影响[J]. 医学临床研究, 2021, 38(10): 1497-1499.
YUAN Li-ping, HE Jin-hua, HU Ji-hong, et al. Effect of Botulinum Toxin Type A Combined with Routine Rehabilitation on Balance Ability and Daily Living Ability of Children with Spastic Hemiplegic Cerebral Palsy. JOURNAL OF CLINICAL RESEARCH, 2021, 38(10): 1497-1499.
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2021, Vol. 38 
