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医学临床研究  2021, Vol. 38 Issue (10): 1497-1499    DOI: 10.3969/j.issn.1671-7171.2021.10.016
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A型肉毒毒素联合常规康复治疗对脑瘫所致痉挛型偏瘫患儿平衡能力及日常生活能力的影响
袁丽平, 何金华, 胡继红, 刘华, 段雅琴, 王益梅
湖南省儿童医院,湖南 长沙 410007
Effect of Botulinum Toxin Type A Combined with Routine Rehabilitation on Balance Ability and Daily Living Ability of Children with Spastic Hemiplegic Cerebral Palsy
YUAN Li-ping, HE Jin-hua, HU Ji-hong, et al
Hunan Children's Hospital,Changsha 410007,China
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摘要 【目的】探讨A型肉毒毒素联合常规康复治疗对脑瘫所致痉挛型偏瘫患儿平衡能力及日常生活能力的影响。【方法】选取2017年1月至2020年6月在湖南省儿童医院康复中心治疗的57例痉挛型偏瘫患儿,其中男38例,女19例,根据家属意愿将其分成对照组(n=26,给予常规康复治疗)和观察组(n=31,注射A型肉毒毒素联合常规康复治疗),两组患儿共治疗3个月。采用综合痉挛量表(CCS)、Berg平衡量表(BBS)与改良Barthel指数量表评估两组患儿治疗前后痉挛程度、平衡能力及生活质量。【结果】治疗前,两组患儿CCS评分比较,差异无统计学意义(P>0.05);治疗后,两组患儿CCS评分均低于治疗前,且观察组低于对照组,差异均有统计学意义(均P<0.05)。治疗前,两组患儿BBS评分、日常生活能力评分比较,差异无统计学意义(P>0.05);治疗后,两组患儿的BBS评分、日常生活能力评分均高于治疗前,且观察组高于对照组,差异均有统计学意义(均P<0.05)。【结论】对痉挛型偏瘫脑瘫患儿采用A型肉毒毒素联合常规康复治疗,可明显改善痉挛型偏瘫脑瘫患儿的平衡功能及日常生活能力,且安全性高,可在临床上推广使用。
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关键词 脑性瘫痪/康复肉毒毒素类/治疗应用医院康复日常生活活动儿童    
Abstract:【Objective】To investigate the effect of botulinum toxin a combined with routine rehabilitation therapy on balance ability and daily living ability of children with spastic hemiplegic cerebral palsy. 【Methods】A total of 57 children with spastic hemiplegia treated in the rehabilitation center of Hunan children's Hospital from January 2017 to June 2020, including 38 males and 19 females, was divided into control group (n=26, given routine rehabilitation treatment) and observation group (n=31, injected with botulinum toxin a combined with routine rehabilitation treatment) according to the wishes of their families. The children in the two groups were treated for 3 months. The spasticity degree, balance ability and quality of life of the two groups were evaluated by comprehensive spasticity scale (CCS), Berg Balance Scale (BBS) and modified Barthel index scale before and after treatment. 【Results】 Before treatment, there was no significant difference between the two groups (P>0.05); After treatment, the scores of comprehensive spasm scale in the two groups were lower than those before treatment, and the observation group was lower than that in the control group, the difference was statistically significant (mean P<0.05). Before treatment, there was no significant difference in Berg Balance Scale score and ADL score between the two groups (P>0.05); After treatment, the Berg Balance Scale score and ADL score of the two groups were higher than those before treatment, and the observation group was higher than that of the control group, the difference was statistically significant (mean P<0.05). 【Conclusion】 Botulinum toxin a combined with routine rehabilitation treatment for children with spastic hemiplegic cerebral palsy can significantly improve the balance function and daily living ability of children with spastic hemiplegic cerebral palsy, with high safety, which can be popularized in clinic.
Key wordsCerebral Palsy/RH    Botulinum Toxins/TU    Hospitals, Convalescent    Activities of Daily Living    Child
收稿日期: 2021-03-11     
中图分类号:  R742.3  
引用本文:   
袁丽平, 何金华, 胡继红, 刘华, 段雅琴, 王益梅. A型肉毒毒素联合常规康复治疗对脑瘫所致痉挛型偏瘫患儿平衡能力及日常生活能力的影响[J]. 医学临床研究, 2021, 38(10): 1497-1499.
YUAN Li-ping, HE Jin-hua, HU Ji-hong, et al. Effect of Botulinum Toxin Type A Combined with Routine Rehabilitation on Balance Ability and Daily Living Ability of Children with Spastic Hemiplegic Cerebral Palsy. JOURNAL OF CLINICAL RESEARCH, 2021, 38(10): 1497-1499.
链接本文:  
http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2021.10.016     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2021/V38/I10/1497
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