Abstract:【Objective】 To compare the clinical efficacy of percutaneous kyphoplasty (PKP) and percutaneous vertebroplasty (PVP) in the treatment of osteoporotic vertebral compression fractures (OVCF). 【Methods】 A total of 76 patients with OVCF were divided into the PKP group (41 cases) and the PVP group (35 cases) according to different operation methods. Clinical efficacy was compared between the two groups. 【Results】 Compared to before operation, the height of anterior vertebral body in both groups were higher after operation, and the kyphosis Cobb angle and visual analogue scale (VAS) were lower(P<0.05). Compared to before treatment, the Oswestry disability index (ODI) scores of the two groups decreased significantly 1 month after treatment, and the Japanese Orthopaedic Association (JOA) low back pain scores increased significantly (P<0.05). Compared to the PVP group, ODI scores of the PKP group decreased significantly, and the JOA scores increased significantly (P<0.05). Compared to the PVP group, the PKP group had higher anterior vertebral height, lower kyphosis Cobb angle, lower bone cement leakage rate, and higher bone cement injection volume and average treatment cost (P<0.05). There was no significant difference in the incidence of adjacent vertebral fracture and postoperative VAS score between the two groups (P>0.05). 【Conclusion】 Both PKP and PVP can safely and effectively improve the clinical efficacy of OVCF patients and relieve the pain of patients. Compared to PVP, PKP has higher treatment cost, but it can better restore the vertebral shape, improve the vertebral height, and reduce the occurrence of bone cement leakage.
张善成. 经皮椎体后凸成形术与经皮椎体成形术治疗骨质疏松性椎体压缩骨折的疗效对比[J]. 医学临床研究, 2021, 38(5): 740-742.
ZHANG Shan-cheng. Comparison of PVP and PKP in the Treatment of OVCF. JOURNAL OF CLINICAL RESEARCH, 2021, 38(5): 740-742.
[1] CAO Z, WANG G, HUI W, et al. Percutaneous kyphoplasty for osteoporotic vertebral compression fractures improves spino-pelvic alignment and global sagittal balance maximally in the thoracolumbar region[J].PLoS One,2020,15(1):e0228341. [2] 吕昊,彭和兵,司捷.低黏度PKP与高黏度PVP治疗骨质疏松性椎体压缩骨折的疗效比较[J].中国中医骨伤科杂志,2020,28(3):44-47. [3] 方忠,贺宝荣,郝定均,等.新型冠状病毒肺炎疫情防控期间骨质疏松性椎体压缩骨折诊疗策略专家共识[J].中华创伤杂志,2020,36(2):117-123. [4] 李青松,章玉冰,陶学顺, 等.PVP与PKP手术治疗Genant3级骨质疏松性椎体压缩骨折:术后延迟性椎体高度丢失的比较[J].颈腰痛杂志,2019,40(3):297-300. [5] 李峰,涂善志,庞争取.经皮椎体后凸成形术对骨质疏松性椎体压缩骨折患者术后血清leptin、APN水平及预后的影响[J].医学临床研究,2018,35(9):1804-1806. [6] 白云鹤,杨红艳,倪杨明.经横突上缘椎弓根外侧路径单侧PVP术治疗L1~L3骨质疏松性椎体压缩骨折[J].颈腰痛杂志,2020,41(3):348-350. [7] COZZOLINO M. Variables associated with endometriosis-related pain: A pilot study using a visual analogue scale[J].Rev Bras Ginecol Obstet,2019,41(3):170-175. [8] ISHIBASHI Y, ADACHI N, KOGA H, et al. Japanese Orthopaedic Association (JOA) clinical practice guidelines on the management of anterior cruciate ligament injury - Secondary publication[J].J Orthop Sci,2020,25(1):6-45. [9] BUDIONO G R, MCCAFFREY M H, PARR W C H, et al. Development of a multivariate prediction model for successful oswestry disability index changes in L5/S1 anterior lumbar interbody fusion for degenerative disc disease[J].World Neurosurg,2021,148(1):e1-e9. [10] 尹思,刘伟,杜恒,等.经皮椎体后凸成形术治疗中上胸椎骨质疏松性椎体压缩骨折[J].临床骨科杂志,2020,23(2):157-160. [11] 唐晶晶,何嘉辉,梁梓扬,等.PKP治疗有无裂隙骨质疏松椎体压缩骨折骨水泥渗漏比较[J].中国矫形外科杂志,2020,28(20):1825-1829. [12] 李凯明,王尚全,李玲慧, 等.囊袋技术与经皮穿刺椎体后凸成形治疗胸腰椎骨质疏松性压缩骨折:评价改善伤椎术后cobb角及减少骨水泥渗漏的Meta分析[J].中国组织工程研究,2020,24(4):650-656. [13] 马玉泉,周建伟,迟成.经皮穿刺脊柱后凸成形术治疗新鲜和陈旧骨质疏松性椎体压缩骨折的临床效果比较[J].中国医刊,2020,55(1):56-60. [14] DIALLO M, KOUITCHEU R, TOUTA A, et al. Percutaneous kyphoplasty using expandable SpineJack® implant for the treatment of osteoporotic vertebral fractures[J].Pan Afr Med J,2020,35(1):136. [15] GRIFFONI C, LUKASSEN JNM, BABBI L, et al. Percutaneous vertebroplasty and balloon kyphoplasty in the treatment of osteoporotic vertebral fractures: a prospective randomized comparison[J].Eur Spine J,2020,29(7):1614-1620.