Abstract：【Objective】 To detect the levels of IgG, IgE and CA19-9 in patients with AIP, and to evaluate the diagnostic value of single and combined detection for AIP. 【Methods】 From January 2016 to June 2020, 112 patients with pancreatitis in our hospital were selected, including 54 patients with acute pancreatitis (AP group), 23 patients with chronic pancreatitis (CP Group), 35 patients with type 1 AIP (AIP group), and 30 healthy volunteers (control group) in our hospital during the same period, The sensitivity and specificity of IgG4, IgE and CA19-9 in the diagnosis of AIP were detected by drawing the receiver operating curve.【Results】 There was no significant difference in serum IgG1, IgG2 and IgG3 levels among the four groups (P>0.05); The serum IgG4 levels of the four groups were significantly higher than those of the control group (P<0.05). There were significant differences in serum IgG, CA19-9 and IgE levels among the four groups (P<0.05). The serum IgG levels in the AP group, the CP Group and the AIP group were higher than those in the control group, and the Serum CA19-9 and IgE levels in the AIP group were higher than those in the AP group, the CP Group and the control group. ROC curve was drawn. The results showed that the sensitivity and specificity of combined detection of IgG4, IgE and CA19-9 were 87.3% and 94.1% respectively, which were higher than those of single detection of each index.【Conclusion】 The levels of IgG4, IgE and CA19-9 in AIP patients were higher than those in AP and CP patients. The combined detection of the three can improve the sensitivity and specificity in the diagnosis of AIP.
朱峰波, 杨莹, 李秋霞. IgG、IgE、CA19-9单独或联合检测对自身免疫性胰腺炎的诊断价值分析[J]. 医学临床研究, 2021, 38(5): 743-746.
ZHU Feng-bo, YANG Ying, LI Qiu-xia. Diagnostic Value of IgG, IgE and CA19-9 in Autoimmune Pancreatitis. JOURNAL OF CLINICAL RESEARCH, 2021, 38(5): 743-746.
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2021, Vol. 38 
