Abstract：【Objective】To investigate the relationship between spine related parameters, clinical characteristics of senile osteoporosis (SOP) and the risk of osteoporotic fracture. 【Methods】A total82 cases of elderly of patients in our hospital from April 2018 to April 2020 were selected as the research objects (observation group); In addition, 82 patients with SOP in our hospital during the same period were selected as the control group. Before treatment, the basic data of gender, age, body mass index (BMI), residential area, smoking, drinking, outdoor sports, family fracture history, previous fracture history, education level, bone mineral density, and spinal parameters [thoracic kyphosis angle (TK), thoracolumbar kyphosis angle (TLK), lumbar lordosis angle (LL)] were collected, ROC was used to analyze the value of bone mineral density, TK, TLK and LL in predicting of of patients with SOP, and then the difference information between the two groups was included in the multivariate logistic regression analysis for quantitative evaluation, so as to determine the risk factors of of of patients with SOP. 【Results】 There was no significant difference in gender, living area, family fracture history and education level between the two groups (P>0.05); The proportion of patients with age ≥ 75 years old, BMI < 18.5 kg/m2, smoking, drinking, no outdoor exercise and previous fracture history in the observation group was significantly higher than that in the control group (P<0.05); The levels of TK and TLK in the observation group were significantly higher than those in the control group, and the levels of bone mineral density and LL in the observation group were significantly lower than those in the control group (P<0.05). ROC analysis confirmed that bone mineral density, TK, TLK and LL could be used to predict of in patients with SOP, AUC were 0.716, 0.882, 0.863 and 0.831 respectively (mean P<0.05). Multivariate logistic regression analysis confirmed that age ≥ 75 years old, BMI < 18.5 kg/m2, smoking, drinking, no outdoor sports, previous history of fracture, BMD ≤ 0.695 g/cm2, TK ≥ 33.550 °,TLK≥23.985 °and LL≤31.450°. It was the risk factor of patients with SOP (P<0.05).【Conclusion】 There are many risk factors for of in patients with SOP, among which TK, TLK and LL are the important risk factors, and clinicians should pay close attention to them.
刘凯, 张小军, 丁涛. 脊柱相关参数和老年骨质疏松症临床特征与老年骨质疏松性骨折发生风险的关系研究[J]. 医学临床研究, 2021, 38(6): 834-837.
LIU Kai, ZHANG Xiao-jun, DING Tao. Relationship between Spine Related Parameters, Clinical Characteristics of Senile Osteoporosis and Risk of Osteoporotic Fracture in the Elderly. JOURNAL OF CLINICAL RESEARCH, 2021, 38(6): 834-837.
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2021, Vol. 38 
