Abstract:【Objective】To explore the effect of abdominal pressure on cardiopulmonary resuscitation (CPR) in emergency patients. 【Methods】A total of 68 patients with cardiac arrest (CA) were randomly divided into two groups (n=34) .Patients in the control group were given traditional chest compressions to perform CPR, while patients in the observation group were given abdominal pressure CPR. The indexes of therapeutic effects and outcomes after 30 minutes of CPR in the two groups of patients were observed and compared. 【Results】The heart rate, mean arterial pressure and arterial oxygen partial pressure in the observation group were significantly better than those in the control group after 30 minutes of CPR, while the arterial carbon dioxide partial pressure were significantly decreased in the control group. The differences were statistically significant between the two groups (P<0.05). In the observation group, the CPR success rate was 67.65% (23/34) , the 24-hour survival rate was 61.76% (21/34) and the survival rate after discharge was 52.94% (18/34), which were significantly higher than those in the control group (41.18%, 14/34), 32.35% (11/34) and 26.67% (9/34),respectively. Those differences were statistically significant between the two groups (P<0.05). The incidence of complications and rib fractures in the observation group was lower than that in the control group, the difference was statistically significant (P<0.05). 【Conclusion】Compared to traditional chest compression CPR, the effect of abdominal pressure CPR has more significant effects. It is worth further clinical application.