双侧上唇改良梯形黏膜肌皮瓣术中应用罗库溴铵对唇腭裂患儿修复效果及术后肌松残余发生率的影响

doi:10.3969/j.issn.1671-7171.2019.06.004

摘要
图/表
参考文献(15)
相关文章 (15)

全文: PDF (0 KB) HTML (1 KB)
输出: BibTeX | EndNote (RIS)

摘要 【目的】探讨双侧上唇改良梯形黏膜肌皮瓣术中应用罗库溴铵对唇腭裂患儿修复效果及术后肌松残余发生率的影响。【方法】选择2015年1月至2019年1月在本院诊治的唇腭裂患儿80例,按随机数表法分为观察组和对照组,每组40例。对照组患儿采用双侧上唇改良梯形黏膜肌皮瓣术治疗,观察组患儿在对照组基础上加用罗库溴铵治疗。比较两组患儿的治疗效果、起效时间、抽搐恢复时间、恢复指数及家长满意度。【结果】两组患儿治疗效果比较差异无统计学意义(P>0.05);观察组患儿麻醉起效时间、抽搐恢复时间以及恢复指数显著低于对照组;家长满意度显著高于对照组,其差异均有统计学意义(P<0.05)。【结论】双侧上唇改良梯形黏膜肌皮瓣术中应用罗库溴铵对唇腭裂患儿修复效果较好,术后肌松残余发生率较低,家长满意度较高。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章

关键词 ：唇裂/外科学, 儿童, 修复外科手术

Abstract：【Objective】To investigate the effect of rocuronium on the repair of cleft lip and palate and the incidence of residual muscle relaxation in bilateral upper lip modified trapezoidal mucosal myocutaneous flaps.【Methods】Eighty children with cleft lip and palate were selected from January 2015 to January 2019. They were randomly divided into observation group and control group with 40 cases in each group. The control group was treated with bilateral upper lip modified trapezoidal mucosal myocutaneous flaps, while the observation group was treated with rocuronium on the basis of the control group. The treatment effect, onset time, convulsion recovery time, recovery index and parents'satisfaction were compared between the two groups.【Results】There was no significant difference in the therapeutic effect between the two groups (P>0.05); the onset time of anesthesia, convulsion recovery time and recovery index in the observation group were significantly lower than those in the control group; the satisfaction degree of parents was significantly higher than that in the control group, and the difference was statistically significant (P < 0.05).【Conclusion】The application of rocuronium bromide in bilateral upper lip modified trapezoidal mucosal myocutaneous flaps is effective in repairing cleft lip and palate in children. The incidence of residual muscle relaxation after operation is low and parents'satisfaction is high.

Key words： Cleft Lip/SU Child Reconstructive Surgical Procedures

收稿日期: 2019-04-04

PACS:

R782.21

基金资助:青年科学基金项目(编号:2017YFC1103300)

通讯作者: **,E-mail:306628787@qq.com

引用本文:

谢群, 胡强, 张瑞瑞, 山超, 杨靖, 刘丹丹, 鲁巧云. 双侧上唇改良梯形黏膜肌皮瓣术中应用罗库溴铵对唇腭裂患儿修复效果及术后肌松残余发生率的影响[J]. 医学临床研究, 2019, 36(6): 1050-1052.
XIE Qun, HU Qiang, ZHANG Rui-rui,et al. Effect of Rocuronium on the Repair of Cleft Lip and Palate and the Incidence of Residual Muscle Relaxation after Operation in Bilateral Upper Lip Modified Trapezoidal Mucosal Myocutaneous Flaps. JOURNAL OF CLINICAL RESEARCH, 2019, 36(6): 1050-1052.

链接本文:

http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2019.06.004 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2019/V36/I6/1050

[1] 潘孟雄,毛峻武,马韬,等.面动脉黏膜肌皮瓣修复舌及口底肿瘤切除后缺损疗效观察[J].中国修复重建外科杂志,2017,31(4):461-464.
[2] 张伟,刘宁,陈方文,等.改良胸大肌肌皮瓣在复发性头颈癌挽救性手术缺损重建中的应用[J].中国口腔颌面外科杂志,2017,15(4):357-360.
[3] 康定鑫, 饶裕泉, 姬斌, 等. 七氟烷和地氟烷对患儿术中罗库溴铵药效动力学的影响[J].中华医学杂志, 2017, 97(6):429.
[4] 吕杰. 罗库溴铵与苯磺顺阿曲库铵麻醉对腹部手术患儿肌松效果及血流动力学的影响[J].医学理论与实践, 2017,4(14):2109-2110.
[5] 刘洁,余琼,王英伟.椎管内巨大肿瘤切除术中突发硬膜下血肿麻醉处理一例[J].临床麻醉学杂志,2017,33(5):519.
[6] 王暖,魏金升.罗库溴铵与顺式阿曲库铵在全麻气管插管中的临床应用价值比较[J].世界最新医学信息文摘,2017,17(53):70-72.
[7] 冯冰冰. 改良皮肤入路肌皮瓣法睑袋整复术的效果观察[J].海南医学, 2014,4(17):2592-2594.
[8] 潘颖丹, 刘艺琴, 肖立伟. 替牙期唇腭裂患儿的正畸治疗[J].国际口腔医学杂志, 2017, 44(4):380-384.
[9] 娄慧全,王卫红,许彪,等.单段腓骨肌皮瓣在修复Ⅱ型上颌骨缺损中的应用[J].国际口腔医学杂志,2017,44(5):576-579.
[10] 艾清秀, 张自雄, 向华. 邻近微型皮瓣在头面部皮肤缺损修复中的运用[J].临床耳鼻咽喉头颈外科杂志,2017,31(14):1100-1102.
[11] Santamaria MP , Neves FLDS , Silveira CA,et al.Connective tissue graft and tunnel or trapezoidal flap for the treatment of single maxillary gingival recessions: a randomized clinical trial[J].J Clin Periodontol,2017,6(5):174-177.
[12] Henriques PG , Okajima LS , Sérgio Siqueira. Surgical reconstruction of the interdental papilla 2 case reports [J].Gen Dent,2018, 37(5):673.
[13] Mardelli PG , Mardelli ME , Bakkour Z . A novel hinged scleral patch graft for the repair of overfiltration and bleb leaks[J].J Glaucoma,2018,4(3):127-129.
[14] Leslie E, Liu H, Carlson J,et al.A Genome-wide association study of nonsyndromic cleft palate identifies an etiologic missense variant in GRHL3[J].Am J Hum Genet, 2016, 98(4):744-754.
[15] 杨汉林, 何希凡, 刘丰,等. 上唇改良梯形黏膜肌皮瓣修复双侧唇裂的临床研究[J].医学临床研究, 2016, 33(11):2104-2106.