穴位注射联合红外线照射对顽固性带状疱疹后神经痛患者SF-MPQ评分及血清P物质、IL-1β水平的影响

doi:10.3969/j.issn.1671-7171.2026.05.017

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摘要 【目的】探讨穴位注射联合红外线照射对顽固性带状疱疹后神经痛(PHN)患者简版麦吉尔疼痛问卷(SF-MPQ)评分及血清P物质、白细胞介素-1β(IL-1β)水平的影响。【方法】选取2022年10月至2024年12月本院收治的90例顽固性PHN患者,按照随机数字表法分为观察组和对照组,每组45例。观察组接受穴位注射联合红外线照射治疗,对照组接受常规红外线照射治疗,两组均持续治疗4周。比较两组患者治疗前后的疼痛程度[SF-MPQ评分中的疼痛分级指数(PRI)评分、视觉模拟评分法(VAS)评分、现时疼痛强度(PPI)评分]、不良情绪[患者健康问卷(PHQ-9)评分、广泛性焦虑量表(DAG-7)评分]、生活质量[生活质量综合评定问卷(GQOL-74)评分]及血清P物质、IL-1β水平。【结果】治疗后,观察组患者PRI、VAS、PPI、PHQ-9、DAG-7评分均低于对照组(P<0.05),血清P物质、IL-1β水平低于对照组(P<0.05),GQOL-74评分高于对照组(P<0.05)。【结论】穴位注射联合红外线照射治疗顽固性PHN的疗效显著,可有效缓解疼痛、不良情绪,提升生活质量,值得临床推广应用。

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	冯冰
	李轲

关键词 ：神经痛,带状疱疹后, 水针疗法, 红外线, P物质, 白细胞介素-1β

Abstract：【Objective】 To explore the effects of acupoint injection combined with infrared irradiation on the Short-Form McGill Pain Questionnaire (SF-MPQ) score and serum levels of substance P and interleukin-1β (IL-1β) in patients with intractable postherpetic neuralgia (PHN). 【Methods】 A total of 90 patients with intractable PHN admitted to our hospital from October 2022 to December 2024 were selected and divided into the observation group and the control group by random number table method, with 45 cases in each group. The observation group was treated with acupoint injection combined with infrared irradiation, while the control group received conventional infrared irradiation alone. Both groups were treated continuously for 4 weeks. Before and after treatment, the two groups were compared in pain degree [Pain Rating Index (PRI), Visual Analogue Scale (VAS) and Present Pain Intensity (PPI) in SF-MPQ], negative emotions [Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7)], quality of life [Generic Quality of Life Inventory-74 (GQOL-74)], as well as serum levels of substance P and IL-1β. 【Results】 After treatment, the scores of PRI, VAS, PPI, PHQ-9 and GAD-7 in the observation group were significantly lower than those in the control group (P<0.05); serum substance P and IL-1β levels were lower than those in the control group (P<0.05); while the GQOL-74 score was higher than that in the control group (P<0.05). 【Conclusion】 Acupoint injection combined with infrared irradiation has a remarkable curative effect on intractable PHN. It can effectively relieve pain and negative emotions, and improve patients' quality of life, which is worthy of clinical promotion and application.

Key words： Neuralgia, Postherpetic Hydro Acupuncture Therapy Infrared Rays Substance P Interleukin-1beta

收稿日期: 2025-04-11

中图分类号:

R752.12

引用本文:

冯冰, 李轲. 穴位注射联合红外线照射对顽固性带状疱疹后神经痛患者SF-MPQ评分及血清P物质、IL-1β水平的影响[J]. 医学临床研究, 2026, 43(5): 766-768.
FENG Bing, LI Ke. Effects of Acupoint Injection Combined with Infrared Irradiation on SF-MPQ Score and Serum Substance P, IL-1β Levels in Patients with Intractable Postherpetic Neuralgia. JOURNAL OF CLINICAL RESEARCH, 2026, 43(5): 766-768.

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http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2026.05.017 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2026/V43/I5/766

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