Abstract：【Objective】To explore the value of invasive Intracranial pressure monitoring in decompressive craniectomy for severe traumatic brain injury (sTBI). 【Methods】A total of 78 sTBI patients who underwent decompressive craniectomy in our hospital from July 2018 to July 2021 were selected and randomly divided into an observation group and a control group, with 39 patients in each group. The control group received decompressive craniectomy, and the observation group used invasive Intracranial pressure monitoring while decompressive craniectomy. The clinical efficacy and postoperative complications of the two groups were compared, including the length of stay in the NICU, the amount of Mannitol, the use time of Mannitol, Intracranial pressure at different time points before and after surgery, and biochemical indicators before and after surgery [interleukin-6 (IL-6), high-sensitivity C-reactive protein (hs-CRP), tumor necrosis factor-α(TNF-α), neuron specific Enolase (NSE)].【Results】The good prognosis rate of the observation group was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). The NICU hospitalization time, Mannitol dosage and Mannitol use time in the observation group were significantly shorter than those in the control group (P<0.05). The intracranial pressure of patients in the two groups was lower than that before operation on the 1st, 3rd and 7th days after operation, with a statistically significant difference (P<0.05); The intracranial pressure of the observation group was lower than that of the control group 3 days and 7 days after operation, with a statistically significant difference (P<0.05). After surgery, two groups of serum IL-6, hs-CRP, TNF-α,the NSE level was lower than those before surgery, and the observation group was lower than the control group, with a statistically significant difference (P<0.05). The total incidence of postoperative complications in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). 【Conclusions】 The use of invasive Intracranial pressure monitoring in decompressive craniectomy for sTBI patients can effectively shorten the hospital stay of NICU, reduce the dosage of Mannitol, restore Intracranial pressure, and significantly improve the neurological function and prognosis of patients.
赵振义, 闵小彬, 樊学海, 郭志刚. 有创颅内压监测用于重型颅脑创伤去骨瓣减压术中的价值[J]. 医学临床研究, 2023, 40(7): 1047-1049.
ZHAO Zhen-yi, MIN Xiao-bin, FAN Xue-hai, et al. The Value of Invasive Intracranial Pressure Monitoring in Decompressive Craniectomy for Severe Traumatic Brain Injury. JOURNAL OF CLINICAL RESEARCH, 2023, 40(7): 1047-1049.
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2023, Vol. 40 
