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Quick Search     Adv Search 2025 Vol. 42, No. 11 Published: 2025-11-26   1845 Application Effect of Continuous Nursing Based on the Uses and Gratifications Theory in Patients with Chronic Rhinosinusitis after Endoscopic Sinus Surgery and its Impact on Patients' Quality of Life LIN Jin, LIN Jian DOI: 10.3969/j.issn.1671-7171.2025.11.002 【Objective】To explore the application effect of continuous nursing based on the Uses and Gratifications Theory in patients with chronic rhinosinusitis (CRS) after endoscopic sinus surgery (ESS) and its impact on patients' quality of life. 【Methods】A total of 84 CRS patients who underwent ESS in our hospital from May 2020 to February 2023 were selected. According to the random number table method, the postoperative patients were divided into the control group (receiving routine postoperative nursing) and the observation group (implementing continuous nursing based on the Uses and Gratifications Theory on the basis of the control group), with 42 cases in each group. The recovery of nasal sinus mucosa (Lund-Kennedy score), Connor-Davidson Resilience Scale (CD-RISC) score, quality of life [Sino-Nasal Outcome Test-20 (SNOT-20) score] and total incidence of complications were compared between the two groups. 【Results】After intervention, the scores of polyps, edema, rhinorrhea, scar and crusting in the observation group were lower than those in the control group (P<0.05). After intervention, the scores of each dimension of CD-RISC in the observation group were higher than those in the control group (P<0.05), and the scores of each dimension of SNOT-20 were lower than those in the control group (P<0.05). The total incidence of complications in the observation group was lower than that in the control group (P<0.05). 【Conclusion】The continuous nursing program based on the Uses and Gratifications Theory can significantly alleviate nasal symptoms, improve quality of life and reduce the total incidence of postoperative complications in CRS patients after ESS, which is worthy of clinical promotion and application. 2025 Vol. 42 (11): 1845-1848 [Abstract] ( 57 ) HTML (1 KB)  PDF (1209 KB)  ( 8 ) 1849 Mechanism of Nerve Growth Factor in Retinal Ganglion Cell Apoptosis in Diabetic Rats LI Donghui, YANG Zhuo, WANG Qichang DOI: 10.3969/j.issn.1671-7171.2025.11.003 【Objective】To explore the mechanism of nerve growth factor (NGF) in the apoptosis of retinal ganglion cells (RGCs) in diabetic rats. 【Methods】 Twenty-four rats were randomly divided into 4 groups, with 6 rats in each group. Normal control group (the NC group): Rats were not treated; Diabetic model group (the DM group): Rats were injected intraperitoneally with streptozotocin (STZ) to establish a DM model; Experimental control group [the DM + adeno-associated virus (AAV) group]: After successfully established DM modeling, AAV + green fluorescent protein (GFP) was injected into the vitreous cavity; Experimental intervention group (the DM + AAV-NGF group): After DM modeling successfully established, AAV + NGF was injected into the vitreous cavity. The b-wave amplitude of each group was measured by electroretinogram (ERG), and the fluorescence staining of retinal tissue sections was observed. The expression levels of NGF, TrkA, P75, AKT, PI3K, Bax, and Caspase3 proteins and mRNAs in each group were detected and compared. 【Results】 The b-wave amplitude in the DM group was lower than that in the NC group, and the b-wave amplitude in the DM + AAV-NGF group was higher than that in the DM group, with statistically significant differences (P<0.05). There were statistically significant differences in the expression levels of NGF, TrkA, P75, AKT, Bax, and Caspase3 proteins and mRNAs among the groups (P<0.05). However, there were no statistically significant differences in the expression levels of PI3K protein and mRNA among the groups (P>0.05). 【Conclusion】 Intravitreal injection of AAV + NGF can inhibit the apoptosis of RGCs in early diabetic rats and improve the retinal function of diabetic rats. The possible mechanism is that it activates the TrkA/P75 receptor, thereby activating the PI3K/Akt pathway and down-regulating the expression levels of Bax and Caspase3. 2025 Vol. 42 (11): 1849-1852 [Abstract] ( 43 ) HTML (1 KB)  PDF (1760 KB)  ( 5 ) 1853 Application of In-Depth and Detailed Intervention Based on Affirmative Effects in Patients with Chronic Obstructive Pulmonary Disease YANG Li, ZHANG Chunyan, ZHOU Shiyang DOI: 10.3969/j.issn.1671-7171.2025.11.004 【Objective】 To explore the application effect of in-depth and detailed intervention based on affirmative effects in health education for patients with chronic obstructive pulmonary disease (COPD).【Methods】 A total of 80 COPD patients were randomly divided into a control group and an observation group, with 40 patients in each group. The control group received conventional health education, while the observation group received in-depth and detailed intervention based on affirmative effects in addition to the conventional education. Pulmonary function, health knowledge acquisition, rehabilitation compliance, emotional status, and quality of life were compared between the two groups before and after two months of intervention.【Results】 After the intervention, the forced expiratory volume in one second (FEV1), forced vital capacity (FVC), and peak expiratory flow rate (PEFR) of patients in the observation group were significantly higher than those in the control group (P< 0.05). The knowledge, attitude, and practice (KAP) scores and all dimensions of rehabilitation compliance in the observation group were also higher than those in the control group(P<0.05). The Hamilton Anxiety Scale (HAMA) and Hamilton Depression Scale (HAMD) scores in the observation group were lower than those in the control group, while the quality of life score in the observation group was significantly higher than that in the control group (P< 0.05).【Conclusion】 In-depth and detailed intervention based on affirmative effects can effectively improve pulmonary function, enhance health knowledge acquisition and rehabilitation compliance, and improve emotional status and quality of life in COPD patients. It is worthy of clinical promotion and application. 2025 Vol. 42 (11): 1853-1856 [Abstract] ( 46 ) HTML (1 KB)  PDF (1208 KB)  ( 3 ) 1857 Therapeutic Efficacy of Roxadustat on Elderly Patients with Chronic Renal Failure Accompanied by Renal Anemia and its Effects on Iron Metabolism HAO Jianbo, HU Chunyu, WANG Lixin DOI: 10.3969/j.issn.1671-7171.2025.11.005 【Objective】To investigate the therapeutic efficacy of roxadustat on elderly patients with chronic renal failure (CRF) accompanied by renal anemia and its effects on iron metabolism.【Methods】Ninety elderly patients with CRF and renal anemia were randomly divided into a control group and an observation group, with 45 cases in each. The control group received recombinant human erythropoietin (rhEPO) injection therapy, while the observation group was treated with roxadustat capsules. The two groups were compared in terms of clinical efficacy, iron metabolism indicators [serum iron (Fe), ferritin (FER), transferrin (TRF)], anemia-related parameters [hemoglobin (Hb), erythropoietin (EPO), hematocrit (HCT)], inflammatory factors [tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and C-reactive protein (CRP)], and incidence of adverse reactions.【Results】After treatment, the total effective rate in the observation group was significantly higher than that in the control group (P<0.05). Serum Fe and TRF levels in the observation group were higher, while FER level was lower than that in the control group (P<0.05). Compared to the control group, the levels of Hb, EPO, and HCT were significantly higher in the observation group (P<0.05),while TNF-α, IL-6, and CRP levels were significantly lower in the observation group (P<0.05). The incidence of adverse reactions showed no significant difference between the two groups (P>0.05).【Conclusion】 Roxadustat can effectively improve iron metabolism and anemia in elderly patients with CRF accompanied by renal anemia and reduce inflammatory responses. 2025 Vol. 42 (11): 1857-1859 [Abstract] ( 60 ) HTML (1 KB)  PDF (1248 KB)  ( 9 ) 1860 Effect of Compex Electromyostimulation and Kinesiology Taping on Early Postoperative Pain and Swelling after Arthroscopic Shoulder Surgery HUANG Junjie, WU Jialong, WU Xiangjie, et al DOI: 10.3969/j.issn.1671-7171.2025.11.006 【Objective】To explore the effect of Compex electromyostimulation and kinesiology taping on early postoperative pain and swelling after arthroscopic shoulder surgery.【Methods】A total of 82 patients with early postoperative pain after arthroscopic shoulder surgery, recruited from Hunan Provincial People's Hospital (the First Affiliated Hospital of Hunan Normal University) from November 2022 to December 2024, were divided into three groups using the random number table method: the conventional rehabilitation group (Group N, n=27), the kinesiology taping group (Group K, n=27), and the Compex electromyostimulation group (Group C, n=28). The patients' pain status, limb swelling relief, insomnia, and rehabilitation satisfaction were evaluated before surgery and at multiple time points after surgery.【Results】At 24 h, 48 h, and 72 h after the first treatment, the effective rate of swelling reduction in Group K was higher than that in Group C and Group N, and that in Group C was higher than that in Group N, with statistically significant differences (P<0.05). On the first night after surgery, the Athens Insomnia Scale (AIS-8) scores of Group K and Group N were significantly higher than those before surgery, with statistically significant differences (P<0.05). On the second and third nights after surgery, the AIS-8 scores of Group C were significantly lower than those of Group K and Group N, with statistically significant differences (P<0.05). On the 1st and 2nd days after surgery, the rehabilitation satisfaction of Group K and Group N was significantly lower than that before surgery, while the rehabilitation satisfaction of Group C was significantly higher than that of Group K and Group N, with statistically significant differences (P<0.05). The analgesic effect of Group C was significantly better than that of Group K and Group N (P<0.05), and there was no statistically significant difference between Group K and Group N (P>0.05).【Conclusion】Compex electromyostimulation can effectively relieve early postoperative pain after arthroscopic shoulder surgery and significantly improve patients' sleep quality; kinesiology taping has a significant advantage in reducing swelling. Both can be used as targeted intervention measures for postoperative rehabilitation after arthroscopic shoulder surgery. 2025 Vol. 42 (11): 1860-1863 [Abstract] ( 38 ) HTML (1 KB)  PDF (1384 KB)  ( 2 ) 1864 Effect of Different Air Self-Cleaning Times between Consecutive Surgeries on Air Quality and Surgical Site Infection in Class Ⅲ Clean Operating Rooms ZHANG Guixiang, HE Cong, LIU Aihua, et al DOI: 10.3969/j.issn.1671-7171.2025.11.007 【Objective】To explore the effect of different air self-cleaning times between consecutive surgeries on air quality and surgical site infection (SSI) in Class Ⅲ clean operating rooms. 【Methods】A cluster randomized design was adopted. Twelve Class Ⅲ clean operating rooms were randomly divided into Groups A, B, C, and D, with the air self-cleaning time between consecutive surgeries set to 5 min, 10 min, 15 min, and 20 min, respectively. Finally, 100 patients (100 surgeries) were included in each group. Immediately after air self-cleaning, the total number of bacterial colonies and the number of 0.5 μm and 5.0 μm dust particles in the central and peripheral areas of the operating room were detected. Meanwhile, the occurrence of SSI within 30 days after surgery was tracked for all patients. 【Results】The qualification rates of bacterial colonies in the peripheral and central areas of Group A were 72.00% and 77.00%, respectively, while those of Groups B-D were all 100.00%. The qualification rates of bacterial colonies in the peripheral and central areas of Group A were significantly different from those of Groups B, C, and D (P<0.05), but there were no significant differences among Groups B, C, and D (P>0.05). The number of 0.5 μm dust particles in Groups A, B, C, and D was (1168.37±19.46) particles/m3, (500.97±12.40) particles/m3, (466.92±12.00) particles/m3, and (445.78±12.44) particles/3, respectively. Group A was significantly different from Groups B, C, and D (P<0.05); there was no significant difference between Group B and Group C (P>0.05), but there was a significant difference between Group B and Group D (P<0.05); no significant difference was found between Group C and Group D (P>0.05). The number of 5 μm dust particles in Groups A, B, C, and D was (314.24±2.18) particles/m3, (166.60±2.39) particles/m3, (148.10±2.24) particles/m3, and (137.92±2.33) particles/m3, respectively, with significant differences among all groups (P<0.05). There was no significant difference in the incidence of SSI among the four groups (P＝0.245). 【Conclusion】For Class Ⅲ clean operating rooms, when the number of medical staff is less than 10 and the surgical incisions are Class Ⅰ or Ⅱ, an air self-cleaning time of 10 min between consecutive surgeries can effectively improve the air quality of the operating room without increasing the risk of SSI, which is beneficial to improving the turnover efficiency of the operating room. 2025 Vol. 42 (11): 1864-1867 [Abstract] ( 38 ) HTML (1 KB)  PDF (1291 KB)  ( 4 ) 1868 Correlation between Serum cys C and BNP Levels and Cardiac Function and Prognosis in Elderly Hypertensive Patients LI Yaru, GUO Wanwan, YANG Yan DOI: 10.3969/j.issn.1671-7171.2025.11.008 【Objective】To explore the correlation between serum cystatin C (cys C) and brain natriuretic peptide (BNP) levels and cardiac function and prognosis in elderly hypertensive patients. 【Methods】A total of 120 elderly hypertensive patients admitted to our hospital from September 2020 to June 2023 were selected. All patients were followed up for 3 years and divided into a good prognosis group (n=74) and a poor prognosis group (n=46) according to whether major adverse cardiovascular events occurred during follow-up. Meanwhile, 57 healthy volunteers who underwent physical examination in our hospital during the same period were selected as the control group. Serum cys C and BNP levels, as well as cardiac function indexes [left ventricular ejection fraction(LVEF),left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), left ventricular ejection fraction (LVEF), 6-minute walk distance (6MWD)] were compared among the three groups. Pearson correlation coefficient was used to evaluate the correlation between serum cys C and BNP levels and prognosis; Spearman correlation analysis was used to analyze the correlation between serum cys C and BNP levels and cardiac function. 【Results】The serum cys C and BNP levels in the poor prognosis group were higher than those in the control group and the good prognosis group, with statistically significant differences (P<0.05). LVEDD and LVESD in the poor prognosis group were significantly higher than those in the control group and the good prognosis group, while LVEF and 6MWD were significantly lower than those in the control group and the good prognosis group, with statistically significant differences (mean P<0.05). Pearson correlation analysis showed that serum cys C and BNP levels were positively correlated with poor prognosis (r=0.464, 0.989; all P<0.05). Spearman correlation analysis showed that serum cys C and BNP levels were significantly correlated with cardiac function indexes (LVEDD, LVESD, LVEF, 6MWD) in elderly hypertensive patients (all P<0.05). 【Conclusion】Serum cys C and BNP levels are abnormally elevated in elderly hypertensive patients, and they can be used as important indicators to evaluate cardiac function and prognosis in elderly hypertensive patients. 2025 Vol. 42 (11): 1868-1871 [Abstract] ( 47 ) HTML (1 KB)  PDF (1210 KB)  ( 15 ) 1872 Application Effect of Continuous Health Management Guided by Self-Regulated Learning Theory in Patients with Diabetic Foot FAN Jinghua, REN Fenru, ZHANG Bang DOI: 10.3969/j.issn.1671-7171.2025.11.009 【Objective】To explore the application effect of continuous health management guided by self-regulated learning theory in patients with diabetic foot. 【Methods】A total of 90 patients with diabetic foot treated in our hospital from June 2022 to January 2025 were selected and divided into a control group and an observation group by stratified random sampling, with 45 cases in each group. The control group received routine health management, while the observation group received continuous health management guided by self-regulated learning theory on the basis of the control group. The stigma [Stigma Scale for Chronic Illness-8 (SSCI-8) score], foot clinical symptoms [Toronto Clinical Scoring System (TCSS) score], self-efficacy [Diabetes Self-Efficacy Scale (DSES) score], and quality of life [Diabetes-Specific Quality of Life Scale (DSQL) score] were compared between the two groups. 【Results】After intervention, the SSCI-8 score and all TCSS scores of the observation group were lower than those of the control group (P<0.05); all DSES scores and all DSQL scores of the observation group were higher than those of the control group (P<0.05). 【Conclusion】The application of continuous health management guided by self-regulated learning theory in patients with diabetic foot can effectively reduce patients' stigma, improve foot neurological symptoms, enhance self-efficacy, and improve quality of life. 2025 Vol. 42 (11): 1872-1875 [Abstract] ( 45 ) HTML (1 KB)  PDF (1259 KB)  ( 2 ) 1876 Effect of Health Education Combined with Psychological Nursing on Compliance Behavior and Mental State of Patients with AIDS Complicated by Tuberculosis ZHANG Ruizi, SU Shuang, JIN Yancai, et al DOI: 10.3969/j.issn.1671-7171.2025.11.010 【Objective】To explore the effect of health education combined with psychological nursing on compliance behavior and mental state of patients with acquired immunodeficiency syndrome (AIDS) complicated by tuberculosis. 【Methods】A total of 266 patients with AIDS complicated by tuberculosis admitted to our hospital from March 2024 to March 2025 were selected and divided into a control group and an observation group using a random number table, with 133 cases in each group. The control group received routine nursing intervention, while the observation group received health education combined with psychological nursing intervention on the basis of routine nursing. Self-efficacy, compliance behavior, Self-Rating Anxiety Scale (SAS) score, Self-Rating Depression Scale (SDS) score and nursing satisfaction were compared between the two groups before and after intervention. 【Results】After intervention, the scores of emotion management, medication management, symptom management, communication with medical staff, social support acquisition and fatigue symptom management in both groups were higher than those before intervention, and the observation group had higher scores than the control group, with statistically significant differences (P<0.05). After intervention, the excellent and good rate of compliance behavior in the observation group was 90.98% (121/133), which was higher than 77.44% (103/133) in the control group, with a statistically significant difference (χ2=9.161, P<0.05). After intervention, the SAS and SDS scores of both groups were lower than those before intervention, and the observation group had lower scores than the control group, with statistically significant differences (P<0.05). After intervention, the nursing satisfaction in the observation group was 89.47% (119/133), which was higher than 78.95% (105/133) in the control group, with a statistically significant difference (χ2=5.542, P<0.05). 【Conclusion】Health education combined with psychological nursing can effectively improve the compliance behavior of patients with AIDS complicated by tuberculosis, alleviate anxiety and depression, and enhance nursing satisfaction, which is worthy of promotion and application. 2025 Vol. 42 (11): 1876-1879 [Abstract] ( 40 ) HTML (1 KB)  PDF (1206 KB)  ( 2 ) 1883 Effects of Different Dual Antiplatelet Therapy Regimens on Blood Lipids, Coronary Artery Blood Flow Status, and Fibrinolytic and Coagulation System Stability in Patients with Acute Myocardial Infarction after PCI HU Yanan, HUA Pengduo, LIU Yang DOI: 10.3969/j.issn.1671-7171.2025.11.012 【Objective】To explore the effects of different dual antiplatelet therapy (DAPT) regimens on blood lipids, coronary artery blood flow status, and fibrinolytic and coagulation system stability in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI). 【Methods】The clinical data of 100 AMI patients who underwent PCI in our hospital from April 2022 to June 2024 were analyzed retrospectively. According to different treatment regimens, the patients were divided into an observation group (n=48, treated with aspirin + ticagrelor DAPT regimen after surgery) and a control group (n=52, treated with conventional aspirin + clopidogrel DAPT regimen after surgery). Both groups received continuous treatment for at least 24 weeks. Blood lipid indexes [triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C)], coronary artery blood flow status indexes [corrected TIMI frame count (CTFC), coronary flow velocity reserve (CFVR), peak systolic velocity (PSV)], and fibrinolytic and coagulation system indexes [platelet aggregation rate, fibrinogen (FIB), tissue-type plasminogen activator (t-PA), antithrombin Ⅲ (AT-Ⅲ)] were compared between the two groups. The incidence of bleeding events and major adverse cardiovascular events (MACE) during treatment was counted in both groups. 【Results】After 24 weeks of treatment, the serum levels of TG, TC, and LDL-C in both groups were lower than those before treatment, while HDL-C was higher than that before treatment; the serum HDL-C level in the observation group was higher than that in the control group, and LDL-C was lower than that in the control group, with statistically significant differences (P<0.05); there were no statistically significant differences in serum TG and TC between the two groups (P>0.05). After 24 weeks of treatment, CFVR and PSV in both groups were higher than those before treatment, and CTFC was lower than that before treatment, with statistically significant differences (P<0.05); there were no statistically significant differences in CFVR, PSV, and CTFC between the two groups (P>0.05). After 24 weeks of treatment, t-PA and AT-Ⅲ in both groups were higher than those before treatment, and platelet aggregation rate and FIB were lower than those before treatment; t-PA and AT-Ⅲ in the observation group were higher than those in the control group, and platelet aggregation rate and FIB were lower than those in the control group, with statistically significant differences (P<0.05). There were no statistically significant differences in the cumulative incidence of bleeding events and MACE between the two groups (all P>0.05). 【Conclusion】Both DAPT regimens can well improve the coronary artery blood flow status of AMI patients after PCI with high safety; however, the aspirin + ticagrelor DAPT regimen can better regulate the patients' blood lipid levels and is more conducive to the stability of the fibrinolytic and coagulation systems. 2025 Vol. 42 (11): 1883-1886 [Abstract] ( 44 ) HTML (1 KB)  PDF (1276 KB)  ( 2 ) 1887 Effect of Hemodialysis Combined with Hemoperfusion on Microinflammatory State and the Occurrence of Cardiac Valve Calcification in Patients with Chronic Renal Failure and Uremia MA Shijing, WEI Qichao, WU Wenli, et al DOI: 10.3969/j.issn.1671-7171.2025.11.013 【Objective】 To investigate the effect of hemodialysis (HD) combined with hemoperfusion on microinflammatory state–related markers and the risk of cardiac valve calcification (CVC) in patients with chronic renal failure and uremia.【Methods】 A total of 156 patients with chronic renal failure and uremia were randomly divided into a control group (the HD alone) and an observation group (the HD combined with hemoperfusion), with 78 cases in each group. Levels of microinflammatory markers [tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6),interleukin-10(IL-10), and high-sensitivity C-reactive protein (hs-CRP)], blood urea nitrogen (BUN), serum creatinine (SCr), β2-microglobulin (β2-MG), parathyroid hormone (PTH), serum potassium (K+), serum calcium (Ca2+), endothelin (ET), and angiotensin Ⅱ (AngⅡ) were compared between the two groups before treatment and 3 months after treatment. The incidence of CVC during blood purification was also compared.【Results】 After treatment, levels of IL-6, IL-10, TNF-α, hs-CRP, BUN, SCr, β2-MG, PTH, K+, ET, and AngⅡ decreased significantly in both groups compared with baseline of pre-treatment (P<0.05), with the observation group showing lower levels than the control group (P<0.05). Ca2+ levels increased significantly in both groups after treatment (P<0.05), and the Ca2+ level in the observation group was higher than that in the control group (P<0.05). There was no significant difference in the incidence of CVC between the two groups after treatment (P>0.05).【Conclusion】 HD combined with hemoperfusion can suppress microinflammatory responses, regulate calcium, phosphorus, and potassium metabolism abnormalities, and alleviate vascular endothelial dysfunction in patients with chronic renal failure and uremia. However, it has no significant effect on the occurrence of CVC. 2025 Vol. 42 (11): 1887-1890 [Abstract] ( 46 ) HTML (1 KB)  PDF (1212 KB)  ( 5 ) 1891 Application of Dyspnea-Graded Rehabilitation Training in Patients with Chronic Obstructive Pulmonary Disease CHEN Kajia, ZHANG Dan, MA Lan DOI: 10.3969/j.issn.1671-7171.2025.11.014 【Objective】To explore the application effect of dyspnea-graded rehabilitation (respiratory difficulty level rehabilitation) training in patients with chronic obstructive pulmonary disease (COPD). 【Methods】 A total of 113 COPD patients who were treated in our hospital from January 2022 to December 2024 were selected as the research subjects. They were divided into the control group (n=56, receiving routine care) and the observation group (n=57, receiving respiratory difficulty level rehabilitation care) according to the random number table method. The pulmonary function indicators [forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC], 6-minute walking test distance (6MWD), modified Medical Research Council respiratory difficulty grading (mMRC) score, negative emotions [Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD)], self-management behavior [Obstructive Sleep Apnea Syndrome Self-Management Behavior Questionnaire], and quality of life [Quality of Life Comprehensive Evaluation Questionnaire (GQOLI-74)] were compared between the two groups before and one month after nursing. 【Results】After nursing, the FVC, FEV1, and FEV1/FVC of the observation group were higher than those of the control group (P<0.05), and the 6MWD was longer than that of the control group (P<0.05). After nursing, the HAMA score, HAMD score, and mMRC score of the observation group were lower than those of the control group (P<0.05), while the scores of each dimension of the OSAS self-management behavior questionnaire and the scores of each dimension of quality of life were higher than those of the control group (P<0.05). 【Conclusion】Applying respiratory difficulty level rehabilitation care to COPD patients can effectively improve the pulmonary function indicators and respiratory conditions of patients, relieve negative emotions, thereby improving patients' self-management behavior and quality of life, and it is worthy of clinical promotion and application. 2025 Vol. 42 (11): 1891-1894 [Abstract] ( 49 ) HTML (1 KB)  PDF (1267 KB)  ( 3 ) 1895 Analysis of Influencing Factors for Potassium Chloride Tablet-Associated Gastric Mucosal Injury WANG Yanyan, LI Yingxiao, ZHU Zhenzhen DOI: 10.3969/j.issn.1671-7171.2025.11.015 【Objective】To explore the influencing factors for potassium chloride tablet-associated gastric mucosal injury. 【Methods】A total of 88 patients who received potassium chloride tablet treatment in our hospital from April 2022 to November 2023 were selected. The Modified Lanza Scale (MLS) for gastric mucosal injury was used to assess whether gastric mucosal injury occurred. According to the presence of gastric mucosal injury, the patients were divided into the occurrence group (n=34, MLS score 1–5) and the non-occurrence group (n=54, MLS score 0). Gender, age, body mass index (BMI), smoking, alcohol consumption, history of peptic ulcer, history of cardiovascular and cerebrovascular diseases, Helicobacter pylori (Hp) infection, levels of prostaglandin E2 (PGE2) and monocyte chemoattractant protein-1 (MCP-1), activated partial thromboplastin time (APTT), prothrombin time (PT), and thrombin time (TT) were compared between the two groups. Multivariate Logistic regression analysis was used to identify the risk factors for potassium chloride tablet-associated gastric mucosal injury, and receiver operating characteristic (ROC) curve was used to analyze the efficacy of each index in predicting this injury. 【Results】There were no statistically significant differences between the two groups in gender, age, BMI, smoking history, alcohol consumption history, history of peptic ulcer, history of cardiovascular and cerebrovascular diseases, or serum levels of PGE2 and MCP-1 (P>0.05); significant differences were found in the proportion of Hp infection, APTT, PT, and TT between the two groups (P<0.05). Multivariate Logistic regression analysis showed that Hp infection and prolonged APTT, PT, and TT were independent risk factors for potassium chloride tablet-associated gastric mucosal injury (P<0.05). Spearman correlation analysis revealed that ulcer diameter, area of thick coating at the ulcer base, area of surrounding mucosal congestion, and number of ulcers were positively correlated with MLS score (rs=0.477, 0.435, 0.492, 0.399; mean P<0.05). The sensitivity (85.29%), specificity (83.33%), accuracy (82.95%), and Kappa value (0.664) of the combined prediction using Hp infection status, APTT, PT, and TT for potassium chloride tablet-associated gastric mucosal injury were higher than those of single indexes (P<0.05).【Conclusion】Clinicians can comprehensively assess the risk of potassium chloride tablet-associated gastric mucosal injury in patients based on Hp infection status and coagulation function indexes. This helps to more accurately identify high-risk patients and take preventive measures in advance. 2025 Vol. 42 (11): 1895-1898 [Abstract] ( 40 ) HTML (1 KB)  PDF (1249 KB)  ( 4 ) 1899 Application Effect of Predictive Intervention Combined with Respiratory Function Exercise in Patients Undergoing Pleural Effusion Drainage XING Yanxin, WANG Qin, WU Xinqing DOI: 10.3969/j.issn.1671-7171.2025.11.016 【Objective】To explore the application effect of predictive intervention combined with respiratory function exercise in patients undergoing pleural effusion drainage. 【Methods】 A total of 82 patients with pleural effusion admitted to our hospital from June 2023 to December 2024 were selected. They were divided into a control group (receiving routine intervention) and an observation group (receiving predictive intervention combined with respiratory function exercise) using a random number table, with 41 cases in each group. Postoperative recovery, pulmonary function indexes, quality of life, and incidence of complications were compared between the two groups. 【Results】One month after intervention, the daily postoperative drainage volume and pain score of the observation group were lower than those of the control group, and the extubation time and hospital stay were shorter than those of the control group, with statistically significant differences (all P<0.05); the forced expiratory volume in 1 second (FEV1) and the ratio of forced expiratory volume in 1 second to forced vital capacity (FEV1/FVC) of the observation group were higher than those of the control group (all P<0.05). The scores of all dimensions of the Quality of Life Index (QOLI) in the observation group were higher than those in the control group (all P<0.05). The total incidence of complications in the observation group was 7.32%, which was significantly lower than 19.51% in the control group, with a statistically significant difference (P<0.05).【Conclusion】Predictive intervention combined with respiratory function exercise is helpful to promote postoperative recovery of patients undergoing pleural effusion drainage, improve pulmonary function and quality of life, and reduce the incidence of complications, which has high clinical application value. 2025 Vol. 42 (11): 1899-1901 [Abstract] ( 44 ) HTML (1 KB)  PDF (1244 KB)  ( 2 ) 1902 Effect of Metoprolol Combined with Early Reperfusion Therapy within 24 Hours after PCI on Cardiac Function and Prognosis of Acute Myocardial Infarction Patients HU Zhenhua, WANG Shouyang, LIU Xuerui DOI: 10.3969/j.issn.1671-7171.2025.11.017 【Objective】To investigate the effect of metoprolol combined with early reperfusion therapy within 24 hours after percutaneous coronary intervention (PCI) on the cardiac function and prognosis of patients with acute myocardial infarction (AMI). 【Methods】 A total of 168 AMI patients admitted to the Department of Cardiology, Huaxian People's Hospital from August 2022 to October 2024 were selected, all of whom received early reperfusion therapy after PCI. Based on treatment methods, the patients were divided into a control group (early reperfusion therapy) and an observation group (administration of metoprolol within 24 hours after PCI in addition to the control group's treatment), with 84 cases in each group. Myocardial injury markers [heart-type fatty acid-binding protein (h-FABP), procollagen type Ⅲ amino-terminal peptide (PⅢNP), galectin-3 (Gal-3)], autonomic nerve function [heart rate variability (HRV) time-domain SDNN, rMSSD, QT interval dispersion (QTd)], cardiac function indices [left ventricular ejection fraction (LVEF), left ventricular fractional shortening (FS), myocardial salvage index (MSI)], and the incidence of major adverse cardiovascular events (MACE) were compared between the two groups.【Results】At 7 days post-PCI (T1), serum h-FABP, PⅢNP, and Gal-3 levels were lower than preoperative levels (T0) in both groups, with the observation group showing significantly lower levels than the control group (P<0.05). At T1, both groups exhibited increased SDNN and rMSSD compared to T0, while QTd was lower than T0. The observation group had significantly higher SDNN and rMSSD and lower QTd than the control group, with statistically significant differences (P<0.05). At 30 days post-operation, LVEF, FS, and MSI in both control and observation groups were higher than those at 72 hours post-operation of corresponding groups, with the observation group showing significantly higher values than the control group (P<0.05). The MACE incidence rate in the observation group was 7.14% (6/84), which was lower than that in the control group's 14.29% (12/84), with a statistically significant difference (χ2=2.354, P<0.05).【Conclusion】Application of metoprolol combined with early reperfusion therapy within 24 hours after PCI can significantly reduce myocardial injury, improve autonomic nerve function and cardiac function, and decrease the incidence of MACE in AMI patients, contributing to improving their prognosis. 2025 Vol. 42 (11): 1902-1905 [Abstract] ( 47 ) HTML (1 KB)  PDF (1214 KB)  ( 3 ) 1906 Efficacy of URSL and PCNL in the Treatment of Upper Ureteral Impacted Calculi after Extracorporeal Shock Wave Lithotripsy Failure CHEN Ye DOI: 10.3969/j.issn.1671-7171.2025.11.018 【Objective】 To investigate the clinical efficacy of minimally invasive ureteroscopic lithotripsy with holmium laser (URSL) and percutaneous nephrolithotomy (PCNL) in the treatment of patients with upper ureteral impacted calculi (UC-UU) after failure of extracorporeal shock wave lithotripsy (ESWL).【Methods】 A total of 108 UC-UU patients who failed ESWL were randomly divided into the URSL group and the PCNL group (54 cases each) using the parity method. The two groups were compared in terms of operative indicators, renal function parameters, inflammatory factor levels, surgical success rate, stone clearance rate, and postoperative complications.【Results】 The operative time in the URSL group was shorter than that in the PCNL group (P<0.05). There were no significant differences between the two groups in intraoperative blood loss and postoperative hospital stay (P>0.05). Compared with preoperative values, both groups showed decreased blood urea nitrogen (BUN) and serum creatinine (SCr) levels, whileinterferon γ (IFN-γ), interleukin-6 (IL-6), and interleukin-12 (IL-12) levels increased significantly after surgery (P<0.05), with the URSL group showing lower inflammatory factor levels than the PCNL group (P<0.05). The surgical success rate and the 2-week postoperative stone clearance rate were higher in the PCNL group than in the URSL group (P<0.05). There was no significant difference in the overall incidence of postoperative complications between the two groups (P>0.05).【Conclusion】 Both URSL and PCNL are safe and effective for the treatment of UC-UU patients after ESWL failure. Compared to PCNL, URSL can shorten operative time, improve renal function, and reduce inflammatory responses, whereas PCNL demonstrates higher surgical success and stone clearance rates. 2025 Vol. 42 (11): 1906-1908 [Abstract] ( 36 ) HTML (1 KB)  PDF (1250 KB)  ( 9 ) 1909 Effect of Transcranial Direct Current Stimulation Combined with Cognitive Training on Motor Function and Cognitive Function in Patients with Traumatic Brain Injury LIU Xiao, LU Zhe DOI: 10.3969/j.issn.1671-7171.2025.11.019 【Objective】To explore the effect of transcranial direct current stimulation (tDCS) combined with cognitive training on motor function and cognitive function in patients with traumatic brain injury (TBI). 【Methods】The clinical data of 120 TBI patients admitted to our hospital from August 2023 to April 2025 were analyzed retrospectively. According to the rehabilitation treatment methods, the patients were divided into an observation group (treated with tDCS combined with cognitive training) and a control group (treated with tDCS alone), with 60 cases in each group. Motor function [Fugl-Meyer Assessment (FMA) score, Berg Balance Scale (BBS) score], cognitive function [Loewenstein Occupational Therapy Cognitive Assessment (LOTCA) score, Rivermead Behavioral Memory Test (RBMT) score], activities of daily living [Barthel Index (BI) score], and levels of neurofunctional markers [brain-derived neurotrophic factor (BDNF), S100β, neuropeptide Y (NPY)] were compared between the two groups. 【Results】After treatment, the FMA-upper limb score, FMA-lower limb score, and BBS score in both groups were higher than those before treatment, and the observation group had higher scores than the control group, with statistically significant differences (P<0.05). After treatment, the LOTCA, RBMT, and BI scores in both groups were higher than those before treatment, and the observation group had higher scores than the control group, with statistically significant differences (P<0.05). After treatment, the serum BDNF level in both groups was higher than that before treatment, while the serum S100β and NPY levels were lower than those before treatment; the observation group had a higher serum BDNF level and lower serum S100β and NPY levels than the control group, with statistically significant differences (P<0.05). 【Conclusion】tDCS combined with cognitive training can significantly improve the motor function, cognitive function, and activities of daily living of TBI patients, and plays a positive role in TBI rehabilitation. 2025 Vol. 42 (11): 1909-1912 [Abstract] ( 45 ) HTML (1 KB)  PDF (1212 KB)  ( 17 ) 1913 Application of PHOX2B Immunohistochemical Staining in Pathological Diagnosis of Hirschsprung's Disease TAN Zhiwen, ZHENG Taiqing, ZUO Guoyu, et al DOI: 10.3969/j.issn.1671-7171.2025.11.020 【Objective】To investigate the expression of PHOX2B (homeobox protein 2B) immunohistochemical staining in the pathological diagnosis of Hirschsprung's disease (HD).【Methods】Pathological specimens from 33 HD patients (the HD group) treated in our hospital from January 2021 to September 2022 were selected, along with intestinal wall pathological specimens from 10 patients diagnosed with intestinal necrosis or perforation (the control group). Both groups underwent PHOX2B and S100 immunohistochemical staining. Results were interpreted based on immunohistochemical reading methods. Microscopic photography of HD dilated segment resection margins after PHOX2B staining was performed, and statistical analysis of image parameters for mature and immature ganglion cells was conducted using image analysis techniques. 【Results】PHOX2B protein was specifically expressed in the nuclei of intestinal wall ganglion cells, while S100 staining was negative in ganglion cells but positive in nerve fibers, Schwann cells, and pericytes. Mature ganglion cell nuclei were large and round, with PHOX2B staining predominantly appearing as light brown; Immature ganglion cell nuclei were small, elongated, or polygonal, with PHOX2B staining mostly dark brown. The long-to-short diameter ratio of mature ganglion cell nuclei was significantly lower than that of immature nuclei (P<0.001), while the area of mature ganglion cell nuclei was significantly larger than that of immature nuclei (P<0.001). PHOX2B expression level was significantly lower in mature ganglion cell nuclei compared to immature ones (P<0.001). 【Conclusion】PHOX2B immunohistochemical staining effectively reflects the presence of ganglion cells in the intestinal wall tissue of HD patients and can synergize with S100 immunohistochemical staining, providing high accuracy and simplicity for the pathological diagnosis of congenital megacolon. 2025 Vol. 42 (11): 1913-1916 [Abstract] ( 38 ) HTML (1 KB)  PDF (2368 KB)  ( 9 ) 1917 Effects of Laparoscopic Hernia Repair and Tension-Free Hernia Repair on Postoperative Pain and Recurrence in Patients with Inguinal Hernia CHENG Gong, FENG Yaguang, CAO Yan DOI: 10.3969/j.issn.1671-7171.2025.11.021 【Objective】To explore the effects of laparoscopic hernia repair and tension-free hernia repair on postoperative pain and recurrence rate in patients with inguinal hernia. 【Methods】Sixty patients with inguinal hernia admitted to our hospital from January 2023 to January 2024 were selected and divided into the laparoscopic group (treated with laparoscopic hernia repair) and the tension-free group (treated with tension-free hernia repair) according to different surgical methods. The surgical time, bleeding volume, time to get out of bed, and length of hospital stay, the postoperative pain levels [Visual Analog Scale (VAS) score], and inflammatory factors [C-reactive protein (CRP), interleukin-6 (IL-6)], as well as the incidence of surgical complications and follow-up recurrence rates were compared between the two groups. 【Results】The laparoscopic group had significantly shorter surgical time, bed time, and hospital stay than the tension-free group, and the amount of bleeding was significantly lower than that of the tension-free group, with statistical significance (P<0.05). From 2 hours to 1 week after surgery, both groups showed a decreasing trend in VAS scores (P<0.05). The VAS scores of the laparoscopic group were significantly lower than those of the tension-free group at 6 and 24 hours after surgery (P<0.05). At 24 hours after surgery, the average levels of serum CRP and IL-6 in both groups were higher than those before surgery, however, serum CRP and IL-6 levels of the laparoscopic group were significantly lower than those of the tension-free group, with statistical significance (P<0.05). The incidence of postoperative complications in the laparoscopic group was 10.00% (3/30), which was significantly lower than that in the tension-free group [33.33% (10/30)], and the difference was statistically significant (χ2=4.812, P=0.028). There was no recurrence during the follow-up period in the laparoscopic group, while the recurrence rate during the follow-up period in the tension-free group was 6.67% (2/30). There was no statistically significant difference in recurrence rate between the two groups during follow-up (χ2=0.517, P=0.472). 【Conclusion】Compared to tension-free hernia repair, laparoscopic hernia repair has better clinical efficacy in treating inguinal hernia, which accelerates patient recovery process, effectively reduces pain and inflammatory reactions, decreases surgical related complications, and has a lower postoperative recurrence rate. 2025 Vol. 42 (11): 1917-1920 [Abstract] ( 43 ) HTML (1 KB)  PDF (1215 KB)  ( 2 ) 1921 Influence of Initiating the PPOS Protocol at Different Menstrual Cycles on Outcome of Assisted Reproduction in Patients with Diminished Ovarian Reserve XING Jingjing, MA Xinxiang, LIU Min, et al DOI: 10.3969/j.issn.1671-7171.2025.11.022 【Objective】To explore the impact of different menstrual cycle initiation of high progesterone state ovulation induction (progesterone primed ovarian stimulation, PPOS) on the pregnancy outcomes of patients with diminished ovarian reserve (DOR). 【Methods】A retrospective analysis was conducted on the clinical data of 216 DOR patients who underwent PPOS treatment in our hospital from January 2018 to December 2023. The patients were divided into the follicular phase initiation group (Group A, n=114) and the luteal phase initiation group (Group B, n=102) based on the initiation timing. The number of retrieved oocytes, the rate of metaphase Ⅱ(MⅡ) oocytes, the number of available embryos, the rate of high-quality embryos on day 3 (D3) of cleavage, clinical pregnancy rate, live birth rate, total dose of gonadotropin (Gn) drugs, the duration of Gn drug use, cycle cancellation rate, and the incidence of ovarian hyperstimulation syndrome (OHSS) were compared between the two groups. 【Results】The number of retrieved oocytes and the MⅡ oocyte rate in Group A were higher than those in the Group B, with statistically significant differences (P<0.05). There were no statistically significant differences in the number of available embryos, the rate of high-quality embryos on D3, clinical pregnancy rate, live birth rate, cycle cancellation rate, and the incidence of OHSS between the two groups (P>0.05). The total dose of Gn drugs and the duration of Gn drug use in Group A were less than those in Group B, with statistically significant differences (P<0.05). 【Conclusion】The follicular phase initiation PPOS protocol can increase the number of retrieved oocytes and the rate of mature oocytes in DOR patients, and can reduce the dose of ovulation induction drugs and the duration of ovulation induction, but it does not significantly improve the clinical pregnancy rate and live birth rate. 2025 Vol. 42 (11): 1921-1923 [Abstract] ( 36 ) HTML (1 KB)  PDF (1249 KB)  ( 8 ) 1924 Effect of Naoxueshu Oral Liquid on Hematoma Absorption and Neuroinflammation in Patients with Residual Hematoma during Recovery after Intracerebral Hemorrhage HAO Yingying, SONG Xiaozheng, LIU Jinhui, et al DOI: 10.3969/j.issn.1671-7171.2025.11.023 【Objective】 To investigate the effects of Naoxueshu Oral Liquid on hematoma absorption and neuroinflammation in patients with residual hematoma during the recovery stage of spontaneous intracerebral hemorrhage (ICH).【Methods】 A total of 78 patients with residual hematoma during ICH recovery were randomly divided into a control group and an observation group, with 39 cases in each. Both groups received standardized ICH treatment, while the observation group was additionally treated with Naoxueshu Oral Liquid. Hematoma absorption, absolute and relative perilesional edema (PHE) volume, edema resolution time, neutrophil-to-lymphocyte ratio (NLR), systemic inflammation response index (SIRI), tumor necrosis factor-α (TNF-α), malondialdehyde (MDA), superoxide dismutase (SOD), and reduced glutathione (GSH) levels were compared between the two groups before and after 30 days of treatment.【Results】After 30 days of treatment, hematoma volume was significantly reduced in both groups (P<0.05), with the observation group showing smaller hematoma volume, higher absorption rate, and shorter complete absorption time than the control group (all P<0.05). PHE volume decreased in both groups (P<0.05), however, the observation group had lower absolute and relative PHE volume and shorter edema resolution time than the control group (all P<0.05). After treatment, NLR, SIRI, and TNF-α levels decreased compared with pretreatment values (P<0.05), and their levels in the observation group were lower than those in the control group (P<0.05). MDA level decreased, while both SOD and GSH levels increased in both groups after treatment (all P<0.05); while the observation group exhibited lower MDA and higher levels of SOD and GSH compared to the control group (P<0.05).【Conclusion】 Naoxueshu Oral Liquid, when combined with conventional rehabilitation therapy, can significantly promote hematoma and perilesional edema absorption, alleviate neuroinflammatory responses, and improve oxidative stress status in patients during the recovery phase of ICH. 2025 Vol. 42 (11): 1924-1927 [Abstract] ( 37 ) HTML (1 KB)  PDF (1214 KB)  ( 2 ) 1928 Value of MRI in Assessing Ovarian Physiological Changes and Physiological Cysts in Women GU Yunze, HE Shunling, WANG Cunqiang DOI: 10.3969/j.issn.1671-7171.2025.11.024 【Objective】To explore the value of magnetic resonance imaging (MRI) in evaluating ovarian physiological changes and physiological cysts in women. 【Methods】A total of 98 women of childbearing age who underwent physical examinations in our hospital from January 2022 to December 2024 were selected, and they underwent both MRI and ultrasound examinations. The ovarian-related indicators in different menstrual cycles were compared. The diagnostic accuracy of ovarian physiological cysts with MRI and ultrasound was evaluated. The receiver operating characteristic (ROC) curve was constructed to analyze the assessment value of MRI and ultrasound in evaluating ovarian physiological changes and physiological cysts. 【Results】There were statistically significant differences in ovarian volume, maximum follicular diameter, and total number of follicles among different menstrual cycles (P<0.05). The diagnostic accuracy of MRI for physiological cysts was higher than that of ultrasound, and the difference was statistically significant (P<0.05). The ROC curve analysis showed that the area under the curve (AUC) value of MRI for diagnosing physiological cysts of the ovaries was significantly higher than that of ultrasound (P<0.05). 【Conclusion】MRI has a significant value in evaluating the physiological changes of ovaries and physiological cysts in women, which is of great clinical significance for guiding accurate clinical diagnosis, reducing unnecessary treatments, and improving the management level of reproductive health. 2025 Vol. 42 (11): 1928-1930 [Abstract] ( 39 ) HTML (1 KB)  PDF (1211 KB)  ( 2 ) 1931 Analysis of Risk Factors for Pulmonary Infection in Elderly Patients with Chronic Obstructive Pulmonary Disease and Nursing Intervention Countermeasures ZHANG Yanfang, HU Yinghui, LIU Xiuli DOI: 10.3969/j.issn.1671-7171.2025.11.025 【Objective】To explore the risk factors for pulmonary infection in elderly patients with chronic obstructive pulmonary disease (COPD) and corresponding nursing intervention countermeasures. 【Methods】A total of 150 elderly COPD patients with pulmonary infection treated in our hospital from January 2022 to July 2024 were selected as the observation group, and another 150 COPD patients without pulmonary infection treated in our hospital during the same period were selected as the control group. Clinical data of patients were collected to analyze the risk factors for pulmonary infection in COPD patients, and corresponding nursing interventions were proposed. 【Results】Univariate analysis showed that age, disease course, length of hospital stay, ventilator-related microbial infection, and history of diabetes mellitus were influencing factors for pulmonary infection in elderly COPD patients (P<0.05); Logistic multivariate regression analysis revealed that advanced age, long disease course, prolonged hospital stay, ventilator-related microbial infection, and history of diabetes mellitus were independent risk factors for pulmonary infection in elderly COPD patients (P<0.05). 【Conclusion】Advanced age, long disease course, prolonged hospital stay, ventilator-related microbial infection, and history of diabetes mellitus are independent risk factors for pulmonary infection in elderly COPD patients. Clinically, targeted nursing interventions should be implemented for elderly COPD patients based on the above-identified risk factors to reduce the incidence of pulmonary infection. 2025 Vol. 42 (11): 1931-1933 [Abstract] ( 37 ) HTML (1 KB)  PDF (1182 KB)  ( 4 ) 1934 Diagnostic Value of Combined Detection of Serum H-FABP and NT-proBNP in Congenital Heart Disease Complicated with Pulmonary Hypertension ZHOU Wei, SHI Lei DOI: 10.3969/j.issn.1671-7171.2025.11.026 【Objective】 To explore the diagnostic value of serum heart-type fatty acid-binding protein (H-FABP) and N-terminal pro-brain natriuretic peptide (NT-proBNP) in patients with congenital heart disease (CHD) complicated with pulmonary hypertension (PH). 【Methods】 A total of 86 patients with CHD were divided into the PH group (n=61) and the non-PH group (n=25) according to the presence or absence of complicated PH. The serum levels of H-FABP and NT-proBNP, as well as pulmonary artery diameter, pulmonary venous blood flow velocity, and pulmonary artery systolic pressure (PASP) were compared between the two groups. Pearson correlation analysis was used to explore the correlations of serum H-FABP and NT-proBNP with pulmonary artery diameter, pulmonary venous blood flow velocity, and PASP, and to evaluate the diagnostic efficacy of these indicators for PH in CHD patients. 【Results】The serum levels of H-FABP, NT-proBNP, blood flow velocity, and PASP in the PH group were significantly higher than those in the non-PH group, and the pulmonary artery diameter in the PH group was significantly larger than that in the non-PH group (all P<0.05). Serum H-FABP and NT-proBNP were positively correlated with pulmonary artery diameter, blood flow velocity, and PASP (all P<0.05). The accuracy of combined detection of H-FABP and NT-proBNP for predicting PH in CHD patients was 95.6%. 【Conclusion】 The serum levels of H-FABP and NT-proBNP are relatively high in CHD patients complicated with PH, and the combined detection of these two indicators has good efficacy for the diagnosis of CHD complicated with PH. 2025 Vol. 42 (11): 1934-1936 [Abstract] ( 47 ) HTML (1 KB)  PDF (1276 KB)  ( 3 ) 1937 Effects of Ultrasound-Guided Fascia Iliac Compartment Block Combined with Intraspinal Anesthesia on Postoperative Analgesia and Stress Response in Elderly Patients Undergoing Femoral Head Replacement WANG Congli, LI Huiyun, WANG Jianping DOI: 10.3969/j.issn.1671-7171.2025.11.027 【Objective】To investigate the effects of ultrasound-guided fascia iliac compartment block (FICB) combined with intraspinal anesthesia on postoperative analgesia and stress response in elderly patients undergoing femoral head replacement. 【Methods】Sixty elderly patients undergoing femoral head replacement were divided according to anesthesia methods into the control group (n=30, receiving intraspinal anesthesia) and the observation group (n=30, receiving ultrasound-guided FICB combined with intraspinal anesthesia). Postoperative pain intensity [visual analogue scale (VAS)] at rest and during movement at 4 h, 8 h, and 24 h, analgesic outcomes, stress response indicators [cortisol (COR), epinephrine (E), and adrenocorticotropic hormone (ACTH)] before surgery and 24 h after surgery, as well as postoperative complications, were compared between the two groups.【Results】At 4 h, 8 h, and 24 h after surgery, VAS scores at rest and during movement decreased gradually in both groups, with statistically significant differences between time points (P<0.05). The VAS scores at all time points were lower in the observation group compared with the control group (P<0.05). The time to first press of the analgesia pump was longer, sufentanil consumption within 24 h was lower, and the rate of rescue analgesia was reduced in the observation group compared with the control group (P<0.05). At 24 h after surgery, COR, E, and ACTH levels were significantly higher than preoperative levels in both groups, but the levels of COR, E, and ACTH in the observation group were lower than those in the control group (P<0.05). The overall incidence of complications in the observation group was also lower than that in the control group (P<0.05).【Conclusion】FICB combined with intraspinal anesthesia can improve postoperative analgesic effects, alleviate stress responses, and reduce the incidence of complications in elderly patients undergoing femoral head replacement. 2025 Vol. 42 (11): 1937-1940 [Abstract] ( 44 ) HTML (1 KB)  PDF (1216 KB)  ( 2 ) 1941 Efficacy of Tubal Compression Surgery in Treatment of Patients with Tubal Pregnancy and its Impact on Pregnancy after Surgery MA Ling, MA Ronghu, SHI Kai, et al DOI: 10.3969/j.issn.1671-7171.2025.11.028 【Objective】To explore the efficacy of tubal compression surgery in treating patients with tubal pregnancy and its impact on postoperative pregnancy. 【Methods】The clinical data of 60 patients with tubal pregnancy admitted to the People's Hospital of Ningxia Hui Autonomous Region from January 2019 to January 2023 were collected. According to the different surgical methods, they were divided into the observation group (undergoing laparoscopic tubal compression surgery) and the control group (undergoing laparoscopic tubal fenestration and embryo removal surgery), with 30 cases in each group. The perioperative related indicators and postoperative pregnancy conditions of the two groups were compared. 【Results】The operation time of the observation group was shorter than that of the control group, and the intraoperative blood loss was less than that of the control group, with statistically significant differences (P<0.05). The hemoglobin value of the observation group on the second day after surgery was higher than that of the control group, with a statistically significant difference (P<0.05). The postoperative exhaust time, postoperative ambulation time, postoperative menstrual recovery time, and hospital stay of the observation group were all shorter than those of the control group, with statistically significant differences (P<0.05). The postoperative tubal patency rate, intrauterine pregnancy rate at 6 months and 1 year of the observation group were higher than those of the control group, with statistically significant differences (P<0.05). 【Conclusion】Tubal compression surgery for treating patients with tubal pregnancy has a shorter operation time, less intraoperative blood loss, faster postoperative recovery, and less impact on subsequent pregnancy. 2025 Vol. 42 (11): 1941-1943 [Abstract] ( 45 ) HTML (1 KB)  PDF (1185 KB)  ( 2 ) 1944 Effects of Traditional Chinese Herbal Fumigation and Washing Treatment on Pruritus Severity and Renal Function in Patients with Uremic Pruritus ZHENG Huajuan, YOU Hua, ZHANG Qing DOI: 10.3969/j.issn.1671-7171.2025.11.029 【Objective】To investigate the effects of traditional Chinese medicine (TCM) fumigation and washing therapy on the severity of pruritus and renal function in patients with uremic pruritus (UP). 【Methods】 A total of 92 patients with UP were randomly divided into the control group and the observation group, with 46 patients in each group. The control group received routine hemodialysis combined with calamine lotion, while the observation group additionally received TCM fumigation and washing for 8 consecutive weeks. Clinical efficacy, pruritus symptom scores, TCM syndrome scores, renal function [blood urea nitrogen (BUN), serum creatinine (SCr)], and calcium-phosphorus metabolism indicators [parathyroid hormone (PTH), serum phosphorus, serum calcium] were compared between the two groups before and after treatment. 【Results】 The overall effective rate in the observation group was significantly higher than that in the control group (P<0.05). After treatment, pruritus severity, pruritus area, pruritus frequency, sleep disturbance scores, TCM syndrome scores, as well as BUN, SCr, PTH, and serum phosphorus levels decreased significantly in both groups, while serum calcium levels increased (P<0.05). Moreover, improvements in all parameters were more significant in the observation group compared to the control group (P<0.05). 【Conclusion】 TCM fumigation and washing treatment can effectively alleviate pruritus symptoms in UP patients and exert a positive effect on improving renal function and regulating calcium-phosphorus metabolism. 2025 Vol. 42 (11): 1944-1946 [Abstract] ( 40 ) HTML (1 KB)  PDF (1243 KB)  ( 2 ) 1947 Application Value of Childlike Intervention in Children with Oral Candidiasis CHEN Qingyun, HAN Xue, WU Shuiru, et al DOI: 10.3969/j.issn.1671-7171.2025.11.030 【Objective】 To explore the application value of childlike intervention in children with oral candidiasis. 【Methods】A total of 80 children with oral candidiasis were randomly divided into an observation group (receiving routine intervention + childlike intervention) and a control group (receiving routine intervention), with 40 cases in each group. The treatment compliance, improvement time of clinical symptoms, psychological status of children and family satisfaction were compared between the two groups. 【Results】 The time for body temperature and white blood cell count to return to normal in the observation group was significantly shorter than that in the control group (P<0.05). The anxiety level (SCAS score) and medical fear level (CMFS score) of the observation group were significantly lower than those before intervention and those of the control group (P<0.05). The excellent and good rate of treatment compliance and the family satisfaction score in the observation group were significantly higher than those in the control group (P<0.05). 【Conclusion】Childlike intervention in the treatment of oral candidiasis can significantly improve children's clinical symptoms, psychological status and treatment compliance, while enhancing family satisfaction, and has a good clinical application prospect. 2025 Vol. 42 (11): 1947-1950 [Abstract] ( 41 ) HTML (1 KB)  PDF (1202 KB)  ( 7 ) 1951 Clinical Efficacy of Fracture Reduction and Internal Fixation Combined with Primary Ligament Treatment in Patients with Tibial Plateau Fractures Complicated by Knee Ligament Injuries CHEN Qingzhi, XIE Huanglin, CHEN Kuo, et al DOI: 10.3969/j.issn.1671-7171.2025.11.031 【Objective】To explore the clinical efficacy of fracture reduction and internal fixation combined with primary ligament treatment in patients with tibial plateau fractures complicated by knee ligament injuries. 【Methods】A retrospective analysis was conducted on 41 patients with tibial plateau fractures complicated by knee ligament injuries admitted to Xiamen Third Hospital from January 2019 to April 2024. All patients underwent fracture reduction and internal fixation combined with primary ligament treatment. The surgical conditions of the patients were recorded, and the Lysholm Knee Scoring System and Tegner Knee Scoring System were used to evaluate the knee joint function of the patients before and after surgery. 【Results】All 41 patients with tibial plateau fractures and ligament injuries were followed up, with a follow-up period of 20.70 (12-29) months. The Lysholm knee score of the patients at 1 year after surgery was (86.20±0.50) points, which was significantly higher than the preoperative score of (28.34±7.12) points, and the difference was statistically significant (P<0.05); the Tegner knee score at 1 year after surgery was (7.43±0.20) points, which was significantly higher than the preoperative score of (3.60±0.90) points, and the difference was statistically significant (P<0.05). A total of 90.8% of the patients returned to the same or lower level of activity. 【Conclusion】Fracture reduction and internal fixation combined with primary ligament treatment for patients with tibial plateau fractures complicated by knee ligament injuries can significantly improve knee joint function and achieve satisfactory efficacy. 2025 Vol. 42 (11): 1951-1954 [Abstract] ( 40 ) HTML (1 KB)  PDF (1678 KB)  ( 3 ) 1955 Clinical Efficacy of Hayman Uterine Compression Suture Combined with Hemabate in the Treatment of Postpartum Hemorrhage after Cesarean Section for Placenta Previa YE Xinhong DOI: 10.3969/j.issn.1671-7171.2025.11.032 【Objective】To explore the clinical efficacy of Hayman uterine compression suture combined with Hemabate in the treatment of postpartum hemorrhage after cesarean section for placenta previa. 【Methods】A total of 76 patients with postpartum hemorrhage after cesarean section for placenta previa admitted to our hospital from February 2023 to February 2025 were selected. According to different treatment methods, they were divided into the control group and the observation group. The control group was treated with Hayman uterine compression suture, while the observation group was treated with Hayman uterine compression suture combined with Hemabate. Surgical-related indicators, clinical efficacy, blood loss at different time points, coagulation function indexes [prothrombin time (PT), thrombin time (TT), activated partial thromboplastin time (APTT)], and occurrence of adverse events were compared between the two groups. 【Results】The hemostasis time and hospital stay of the observation group were shorter than those of the control group (P<0.05); the total effective rate of treatment in the observation group was higher than that in the control group (P<0.05); the intraoperative blood loss, blood loss at 2 h and 24 h after surgery in the observation group were less than those in the control group (P<0.05); at 24 h after surgery, PT, TT and APTT in the observation group were shorter than those in the control group (P<0.05); there was no statistically significant difference in the total incidence of adverse events between the two groups (P>0.05). 【Conclusion】Hayman uterine compression suture combined with Hemabate can effectively control the postoperative blood loss of patients with postpartum hemorrhage after cesarean section for placenta previa, improve coagulation function indexes, promote postoperative recovery, and has good safety. 2025 Vol. 42 (11): 1955-1958 [Abstract] ( 37 ) HTML (1 KB)  PDF (1207 KB)  ( 8 )

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