中药熏洗法对尿毒症皮肤瘙痒症患者皮肤瘙痒程度及肾功能的影响

doi:10.3969/j.issn.1671-7171.2025.11.029

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Abstract 【Objective】To investigate the effects of traditional Chinese medicine (TCM) fumigation and washing therapy on the severity of pruritus and renal function in patients with uremic pruritus (UP). 【Methods】 A total of 92 patients with UP were randomly divided into the control group and the observation group, with 46 patients in each group. The control group received routine hemodialysis combined with calamine lotion, while the observation group additionally received TCM fumigation and washing for 8 consecutive weeks. Clinical efficacy, pruritus symptom scores, TCM syndrome scores, renal function [blood urea nitrogen (BUN), serum creatinine (SCr)], and calcium-phosphorus metabolism indicators [parathyroid hormone (PTH), serum phosphorus, serum calcium] were compared between the two groups before and after treatment. 【Results】 The overall effective rate in the observation group was significantly higher than that in the control group (P<0.05). After treatment, pruritus severity, pruritus area, pruritus frequency, sleep disturbance scores, TCM syndrome scores, as well as BUN, SCr, PTH, and serum phosphorus levels decreased significantly in both groups, while serum calcium levels increased (P<0.05). Moreover, improvements in all parameters were more significant in the observation group compared to the control group (P<0.05). 【Conclusion】 TCM fumigation and washing treatment can effectively alleviate pruritus symptoms in UP patients and exert a positive effect on improving renal function and regulating calcium-phosphorus metabolism.

Key words： remia Pruritus Traditional Chinese Medicine Therapy Kidney Function Tests

Received: 15 March 2024

PACS:

R692.5

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	ZHENG Huajuan
	YOU Hua
	ZHANG Qing

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ZHENG Huajuan,YOU Hua,ZHANG Qing. Effects of Traditional Chinese Herbal Fumigation and Washing Treatment on Pruritus Severity and Renal Function in Patients with Uremic Pruritus[J]. JOURNAL OF CLINICAL RESEARCH, 2025, 42(11): 1944-1946.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2025.11.029 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2025/V42/I11/1944

[1] 高爽,叶盛梅,佟瑞华. 血液灌流联合血液透析对尿毒症性皮肤瘙痒患者钙磷代谢、炎症指标及生活质量的影响[J].中国临床医生杂志,2023,51(7):820-823.
[2] 杨星,罗琰琨. 慢性肾脏病相关性皮肤瘙痒的治疗现状及未来展望[J].实用临床医药杂志,2023,27(6):141-144.
[3] 渠雅君,刘洋,李婉雯,等. 中医外治法治疗尿毒症瘙痒临床应用进展[J].国际中医中药杂志,2024,46(1):124-128.
[4] 王海燕.肾脏病学[M].3版.北京:人民卫生出版社,2008:1815.
[5] 赵辨.中国临床皮肤性病学[M].南京:江苏科学技术出版社,2010:32-33.
[6] 魏跃钢.现代中医皮肤性病学[M].南京:东南大学出版社,2007:6-8.
[7] 国家中医药管理局.中药新药临床研究指导原则[S].北京:中国医药科技出版社,2002.
[8] 王先锋. 中药熏洗联合血液透析与炉甘石洗剂治疗尿毒症伴皮肤瘙痒临床研究[J].新中医,2020,52(19):111-113.
[9] 王华,梁辑,詹元英,等. 硫代硫酸钠联合氯雷他定治疗尿毒症瘙痒症的疗效分析[J].中华保健医学杂志,2022,24(2):122-124.
[10] TRACHTENBERG A J, COLLISTER D, RIGATTO C. Recent advances in the treatment of uremic pruritus[J].Curr Opin Nephrol Hypertens,2020,29(5):465-470.
[11] LU P H, WANG J Y, CHUO H E,et al . Effects of uremic clearance granules in uremic pruritus: a meta-analysis[J].Toxins (Basel),2021,13(10):702.
[12] 张文钰,张琳. 从“风伏肾络”探讨尿毒症相关性皮肤瘙痒[J].山东中医药大学学报,2023,47(5):599-602.
[13] 邓彩春,曾翠青,黄日珍,等. 虎符铜砭刮痧治疗尿毒症皮肤瘙痒的效果及其对C反应蛋白和白细胞介素-6水平的影响[J].临床与病理杂志,2023,43(6):1213-1219.
[14] 丁同凤,姚兴梅,彭文,等. 耳穴贴压改善腹膜透析尿毒症瘙痒症患者的临床疗效观察及机制探讨[J].中国中西医结合肾病杂志,2019,20(3):243-245.
[15] 陈娟娟,刘素贞,杨义芳,等. 血液灌流联合高通量血液透析对尿毒症性皮肤瘙痒的疗效及其对患者钙磷代谢和肾功能的影响[J].中国医学前沿杂志(电子版),2021,13(2):89-92.