Efficacy of Transcranial Magnetic Stimulation Combined with Whole-Body Vibration Training in the Treatment of Swallowing, Cognitive, and Lower Limb Function in Stroke Patients
LI Aijing, WANG Jingmin, JIN Fang
Department of Rehabilitation Medicine, Hebi People's Hospital, Hebi Henan 458030
Abstract：【Objective】 To explore the effects of transcranial magnetic stimulation (TMS) combined with whole-body vibration training (WBVT) on swallowing, cognitive, and lower limb function in stroke patients.【Methods】 A total of 126 stroke patients were randomly divided into two groups: the control group (63 patients) and the observation group (63 patients). Patients in the control group received conventional treatment, while those in the observation group received TMS combined with WBVT on top of conventional therapy. After 4 weeks of treatment, the differences in swallowing function [Standardized Swallowing Assessment (SSA), Penetration-Aspiration Scale (PAS)], cognitive function [Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA)], and lower limb function [Berg Balance Scale (BBS), Holden Ambulation Index (FAC)] and levels of serum albumin (ALB), hemoglobin (Hb), homocysteine (Hcy), and VILIP-1 were compared between the two groups.【Results】After treatment, swallowing function, cognitive function, and lower limb function significantly improved in both groups (P<0.05). The observation group showed significantly lower SSA and PAS scores and significantly higher scores of MMSE, MoCA, BBS, and FAC compared to the control group (P<0.05). Serum ALB and Hb levels in the observation group were significantly higher than those in the control group, while Hcy and VILIP-1 levels in the observation group were significantly lower than those in the control group (P<0.05).【Conclusion】TMS combined with WBVT can effectively improve swallowing function, cognitive function, and lower limb function in stroke patients, thereby enhancing their quality of life.
栗爱静, 王静敏, 靳芳. 经颅磁刺激联合全身振动训练对脑卒中患者吞咽、认知及下肢功能的影响[J]. 医学临床研究, 2025, 42(1): 60-63.
LI Aijing, WANG Jingmin, JIN Fang. Efficacy of Transcranial Magnetic Stimulation Combined with Whole-Body Vibration Training in the Treatment of Swallowing, Cognitive, and Lower Limb Function in Stroke Patients. JOURNAL OF CLINICAL RESEARCH, 2025, 42(1): 60-63.
[1] ZHOU L, JIN Y J, WU D L, et al. Current evidence, clinical applications, and future directions of transcranial magnetic stimulation as a treatment for ischemic stroke[J].Front Neurosci,2023, 17(11): 1177-1183. [2] 毛璐熙,张安琪,黄昆,等. 全身振动训练对脑卒中偏瘫患者平衡功能及运动功能的影响[J].中国康复,2023,38(8):480. [3] 郑海农,林益芳,蒋爱敏. 新版中国脑血管疾病分类中关于缺血性脑血管病及出血性脑血管病修订的疾病名介绍[J].心脑血管病防治,2018,18(2):91. [4] 赵锦颖,韩宇洲. 标准吞咽功能评估量表联合标准饮食护理在脑血管病吞咽障碍患者中的应用价值[J].河北医药,2019,41(13):2066-2069. [5] 颜维,董庭瑄,崔亚,等. 揿针联合开窍利咽按摩法对缺血性卒中吞咽障碍患者吞咽功能评价量表和功能性经口摄食量表评分的影响[J].河北中医,2023,45(9):1521-1525. [6] 连士英. 简易智能精神状态检查量表在评价血管性痴呆护理效果中的应用[J].齐鲁护理杂志,2014(11):49-50. [7] 杨谦,第五永长,王威,等. 蒙特利尔认知评估量表用于社区轻度认知障碍筛查的初步研究[J].中风与神经疾病杂志,2022,39(2):139-142. [8] 赵春艳,周嫣,赵慧华,等. 静态平衡仪与Berg平衡量表对老年住院患者跌倒风险预测价值差异的研究[J].中华现代护理杂志,2017,23(29):3717-3721. [9] 王海波,陶媛媛,李静,等. 经颅直流电刺激协同患侧下肢强制性负重训练对脑卒中Pusher综合征的效果[J].中国康复理论与实践,2023,29(3):269-274. [10] 刘伟,陆悦,张社卿,等. 左心房黏液瘤并发脑卒中的临床表现及影像学特征分析[J].安徽医药,2021,25(6):1147-1150. [11] 李海宁,陈英道,黄敏,等. 重复经颅磁刺激对脑卒中后认知功能障碍患者认知功能、中枢运动传导时间及平衡能力的影响[J].中国康复,2023,38(3):140-143. [12] 赖丽婷,林润,彭志华,等. 针刺联合经颅磁刺激治疗脑卒中后认知障碍的系统评价与Meta分析[J].广州中医药大学学报,2023,40(7):1838-1846. [13] LIU Q Q, LI W B, ZHAO Z G, et al. Low-frequency repetitive transcranial magnetic stimulation to the right Broca mirror area for improving auditory comprehension in a sensory aphasia after stroke: a case report[J].Folia Neuropathol,2022, 60(2): 257-260. [14] 姜恒蔚,于丽瑛,由健,等. 全身振动训练在脑卒中偏瘫患者中的应用效果[J].国际医药卫生导报,2023,29(11):1578-1582. [15] 曲志芳,李明亮,陈晓茹,等. 孕晚期营养指标血红蛋白和白蛋白对产后外感发热患者治疗效果的影响[J].河北医科大学学报,2016,37(12):1445. [16] 宋春丽,默瑞兴. Hcy、BNP纳入老年冠心病慢性心衰无胸痛症状患者心血管事件预测模型的可行性分析[J].河北医药,2019,41(10):1469-1472. [17] 杜波,李海亮,丁红梅,等. 急性脑梗死患者血清Cav-1、VILIP-1、UCH-L1与神经功能损伤程度、脑梗死面积和预后的关系研究[J].现代生物医学进展,2023,23(22):4294-4298.
2025, Vol. 42 
