CT冠状动脉造影血流储备分数在心脏病变中的诊断价值

doi:10.3969/j.issn.1671-7171.2022.12.010

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摘要【目的】探讨CT冠状动脉造影血流储备分数(FFRCT)在心脏病变中的诊断价值。【方法】选择两院收治的75例心脏病患者为研究对象,通过冠状动脉CT造影检查(CCTA),冠状动脉造影检查(CAG)以及有创血流储备分数(FFR)检查获得患者相应的图像以及数据,建立FFRCT模型,分析FFRCT技术在冠心病患者中分别以患者为单位和以血管支数为单位检测中的敏感性、特异性以及准确性等,同时探讨FFRCT测定值与有创FFR测定值的相关性。【结果】本组75例患者共发现病变血管100支,其中左前降支病变58例,左回旋支病变16例,右冠状动脉26例。以有创FFR为标准,以患者为单位FFRCT检测结果的特异性、敏感性、阳性预测值、阴性预测值、准确性以及κ值分别为100.0%、87.6%、100.0%、50.0%、89.7%、0.62;以血管支数为单位FFRCT检测结果的特异性、敏感性、阳性预测值、阴性预测值、准确性以及κ值分别为100.0%、65.3%、100.0%、50.0%、76.4%、0.51;以患者为单位、以血管支数为单位,FFR与FFRCT均呈正相关,具有良好的一致性(r=0.794、0.725,P<0.05)。【结论】FFRCT技术在CAD患者冠状动脉检测中具有较高的应用价值,临床可以推广FFRCT技术,为患者合理选择诊疗策略提供参考。

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	杨帆
	袁海军

关键词 ：心脏病/诊断, 体层摄影术,X线计算机, 血流储备分数,心肌

Abstract：【Objective】To investigate the diagnostic value of CT coronary angiography blood flow reserve fraction (FFRCT) in heart disease. 【Methods】A total of 75 patients with heart disease in our Hospital were selected as the research objects. The corresponding images and data were obtained by coronary CT angiography (CCTA),coronary angiography (CAG) and invasive blood flow reserve fraction (FFR). The FFRCT model was established to analyze the sensitivity,specificity and accuracy of FFRCT in the detection of blood vessel as the unit and the number of vessels in coronary heart disease. The correlation between FFRCT and invasive FFR was also investigated. 【Results】A total of 100 lesions were found in 75 patients,including 58 left anterior descending lesions,16 left circumflex lesions,and 26 right coronary arteries. Based on the invasive FFR,the specificity,sensitivity,positive predictive value,negative predictive value,accuracy and κ of the FFRCT test results were 100.0%,87.6%,100.0%,50.0%,89.7% and 0.62,respectively. The specificity,sensitivity,positive predictive value,negative predictive value,accuracy and κ of the FFRCT test results in terms of vessel count were 100.0%,65.3%,100.0%,50.0%,76.4% and 0.51,respectively. In units of patients and blood vessels,FFR and FFRCT were positively correlated with good consistency(r=0.794、0.725,P<0.05). 【Conclusion】FFRCT technology has a high value in the detection of coronary artery disease in patients with coronary heart disease. The clinical application of FFRCT technology should be used to rationally select the diagnosis and treatment strategy for patients.

Key words： Heart Diseases/DI Tomography, X-Ray Computed Fractional Flow Reserve, Myocardial

收稿日期: 2022-02-20

中图分类号:

R541

通讯作者: * E-mail:714794827@qq.com

引用本文:

杨帆, 袁海军. CT冠状动脉造影血流储备分数在心脏病变中的诊断价值[J]. 医学临床研究, 2022, 39(12): 1792-1795.
YANG Fan, YUAN Hai-jun. Diagnostic Value of CT Coronary Flow Reserve Fraction in Heart Disease. JOURNAL OF CLINICAL RESEARCH, 2022, 39(12): 1792-1795.

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http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2022.12.010 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2022/V39/I12/1792

[1] 何继强,陈方. 冠状动脉CT造影的无创血流储备分数(FFRCT)在冠心病诊治中的研究进展[J].心肺血管病杂志,2015,34(3):232-235.
[2] KOLLI K K,ARIF I,PEELUKHANA S V,et al. Diagnostic performance of pressure drop coefficient in relation to fractional flow reserve and coronary flow reserve[J].J Invasive Cardiol,2016,87(2):273-282.
[3] KAWATA T,DAIMON M,HASEGAWA R,et al. Prognostic value of coronary flow reserve assessed by transthoracic Doppler echocardiography on long-term outcome in asymptomatic patients with type 2 diabetes without overt coronary artery disease[J].Cardiovasc Diabetol,2013,12(1):121.
[4] 赵冠棋,刘广忠,李为民. 从冠状动脉CT血管成像获得的无创血流储备分数研究新进展[J].中国医学影像学杂志,2015,22(5):83-86.
[5] BANOVIC M,VUJISI-TESIC B,BOJIC S,et al. Diagnostic value of NT-proBNP in identifying impaired coronary flow reserve in asymptomatic moderate or severe aortic stenosis[J].Biomark Med,2013,7(2):221-227.
[6] PARKER M W. Comparison of the diagnostic accuracy of PET and SPECT for coronary artery disease[J].Curr Cardiovasc Imaging Rep,2015,8(1):9302.
[7] 范国鑫,骆家晨,祁小龙,等. 基于CT的血流储备分数研究进展[J].中华实用诊断与治疗杂志,2014,28(8):729-731.
[8] 张晓娇,侯爱洁,罗德锋,等. 基于血流储备分数标准评估冠状动脉CT、血管内超声、冠状动脉造影定量分析在中重度病变的诊断价值[J].中国循证心血管医学杂志,2018,10(9):52-55.
[9] KOLLI K K,HOEF T P V D,EFFAT M A,et al. Diagnostic cutoff for pressure drop coefficient in relation to fractional flow reserve and coronary flow reserve:a patient-level analysis[J].Catheter Cardiovasc Interv,2016,87(2):273-282.
[10] 刘鹏,孙昊洋,姜顺. 血流储备分数CT成像预测冠状动脉临界病变患者功能性心肌缺血的临床价值[J].临床误诊误治,2019,32(5):73-78.
[11] 窦冠华,杨俊杰,单冬凯,等. 冠状动脉CT血管成像定量分析在诊断冠状动脉血流动力学异常中的价值[J].中华放射学杂志,2018,52(9):660-667.
[12] 王丽. 心肌血流储备分数在冠状动脉病变中应用的意义[J].中国中西医结合急救杂志,2017,23(2):223-224.