Abstract:【Objective】To explore the predictive power of platelet distribution width (PDW) combined with stress blood glucose increase ratio (SHR) for heart failure after acute myocardial infarction. 【Methods】Seventy six patients with acute myocardial infarction admitted to the hospital from January 2018 to January 2020 were selected, and 68 healthy patients who came to the hospital for physical examination during the same period were selected. The PDW and SHR of patients with acute myocardial infarction and healthy people were compared, follow-up for 1 year after treatment, the incidence of heart failure in patients with acute myocardial infarction was counted. The clinical characteristics of patients with acute myocardial infarction with heart failure and without heart failure, Logistic multiple regression analysis was used to determine the factors affecting heart failure in patients with acute myocardial infarction, the receiver operator characteristic (ROC) curve was used to analyze the efficacy of PDW combined with SHR in predicting heart failure in patients with acute myocardial infarction.【Results】The PDW and SHR of patients with acute myocardial infarction were higher than those of healthy people (P<0.05). After 1 year of follow-up, the incidence of heart failure in patients with acute myocardial infarction was 28.38%. Compared with patients without heart failure, the composition ratio of multivessel disease and left ventricular ejection fraction, PDW, SHR of patients with heart failure were significantly different (P<0.05). Logistic multivariate regression analysis showed that PDW, SHR, and left ventricular ejection fraction were all independent risk factors for heart failure in patients with acute myocardial infarction (P<0.05). ROC curve analysis showed that the best cutoff points for PDW and SHR to predict the occurrence of heart failure in patients with acute myocardial infarction were 20.086% and 1.250, respectively. The specificity and AUC of the combination of PDW and SHR were 98.11% and 0.889, respectively, which were higher than those predicted by PDW and SHR alone.【Conclusion】 PDW and SHR are abnormally elevated in patients with acute myocardial infarction. PDW and SHR are independent risk factors for heart failure in patients with acute myocardial infarction. The combination of PDW and SHR is of high value in predicting heart failure in patients with acute myocardial infarction.
黄佳雯, 张美娟, 周煜. 血小板分布宽度联合应激性血糖升高比值对急性心肌梗死后心力衰竭的预测效能[J]. 医学临床研究, 2022, 39(9): 1291-1294.
HUANG Jia-wen, ZHANG Mei-juan, ZHOU Yu. Value of Platelet Distribution Width Combined with Stress Hyperglycemia Ratio in Predicting Heart Failure in Patients with Acute Myocardial Infarction. JOURNAL OF CLINICAL RESEARCH, 2022, 39(9): 1291-1294.
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