Abstract：【Objective】 To study the effect of different treatments of Liliequist membrane on the risk of complications in patients with aneurysmal subarachnoid hemorrhage.【Methods】A total of 70 patients with aneurysmal subarachnoid hemorrhage admitted to our hospital from January 2020 to January 2022 were selected as the study subjects. They were randomly divided into the observation group (35 cases) and the control group (35 cases). Both groups underwent intracranial aneurysm clipping. In the observation group, the Liliequist membrane was opened during the operation, while in the control group, the Liliequist membrane was not opened during the operation. The clinical effects of the two groups were compared; The scores of Glasgow Coma Scale (GCS), Modified Rankin Scale (mRS) and Montreal Cognitive Assessment Scale (MoCA) were compared between the two groups before operation and one month after operation; Serum levels of matrix metalloproteinase-9 (MMP-9), high mobility group protein 1 (HMGB1), vascular endothelial growth factor (VEGF) and postoperative complications were compared before and one month after surgery.【Results】Compared with the control group (60.00%), the total effective rate of the observation group (82.86%) was higher (P<0.05); After operation, GCS and MoCA scores were improved, while mRS scores were decreased in both groups (P<0.05); After operation, compared with the control group, the GCS and MoCA scores of the observation group were higher, while the mRS scores were lower (P<0.05); After operation, the level of MMP-9 increased, while the levels of HMGB1 and VEGF decreased in both groups (P<0.05); After operation, the levels of MMP-9, HMGB1 and VEGF in the observation group were lower than those in the control group (P<0.05); Compared with the control group (37.14%), the incidence of postoperative complications in the observation group (14.29%) was lower (P<0.05). 【Conclusion】In the treatment of aneurysmal subarachnoid hemorrhage with aneurysm clipping, opening the Liliequist membrane during the operation can improve the therapeutic efficiency, improve the cognitive function and prognosis of patients, and reduce the incidence of hydrocephalus and other complications.
陈斌, 张冬子. Liliequist膜不同处理方式对动脉瘤性蛛网膜下腔出血患者并发症发生风险的影响[J]. 医学临床研究, 2022, 39(10): 1471-1473.
CHEN Bin, ZHANG Dong-zi. Effects of Different Treatments of Liliequist Membrane on the Risk of Complications in Patients with Aneurysmal Subarachnoid Hemorrhage. JOURNAL OF CLINICAL RESEARCH, 2022, 39(10): 1471-1473.
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2022, Vol. 39 
