Abstract：【Objective】 To investigate the clinical effect of craniotomy clipping and interventional embolization in the treatment of cerebral aneurysmal subarachnoid hemorrhage (aSAH).【Methods】 The clinical data of 96 patients with aSAH admitted to our hospital from February 2014 to may 2018 were retrospectively analyzed. According to the different treatment methods, they were divided into clipping group (n=41) and interventional group (n=55). The interventional group was treated with interventional embolization, and the clipping group was treated with craniotomy and clipping. The prognosis, incidence of complications, immune function and cytokine levels were compared between the two groups. 【Results】 At 7 days after operation, CD3+ and CD8+ in the interventional group were lower than those in the clipping group, while CD4+, CD4+/CD8+ in the intervention group were higher than those in the clipping group (P<0.05). Before operation, there was no significant difference in serum IL-6 and TNF-α levels between the two groups (P>0.05); 7 days after operation, the serum levels of IL-6 and TNF -α in the interventional group were lower than those in the clipping group (P<0.05). 3 months after operation, the prognosis of the interventional group was better than that of the clipping group,but there was no significant difference(P>0.05). 3 months after operation, the complication rate of the interventional group was 20.0% (11 / 55), which was lower than that of the clipping group 56.1% (23/41), the difference was statistically significant (P<0.05).【Conclusion】 The clinical effect of interventional embolization in the treatment of aSAH patients is better, and it has less impact on the immune function of patients, which helps to reduce the incidence of complications, which is worthy of clinical application.
2020, Vol. 37 
