医学临床研究
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医学临床研究  2020, Vol. 37 Issue (6): 895-897    DOI: 10.3969/j.issn.1671-7171.2020.06.029
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子宫动脉栓塞联合甲氨蝶呤、依沙吖啶和米非司酮在晚期完全性前置胎盘引产中的应用
王静, 卢英, 杨雪琴
凉山州中西医结合医院妇产科,四川 凉山 615000
Application of Uterine Artery Embolization Combined with Methotrexate, Ethacridine and Mifepristone in Induction of Labor in Late Complete Placenta Previa
WANG Jing, LU Ying, YANG Xue-qin
Department of Obstetrics and Gynecology,Liangshan Prefecture Integrated Traditional Chinese and Western Medicine Hospital,Liangshan, Sichuan,615000
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摘要 目的】 探讨子宫动脉栓塞联合甲氨蝶呤、依沙吖啶和米非司酮在完全性前置胎盘妊妇引产中的应用效果。【方法】 回顾性分析2014年3月至2018年3月在本院接受诊治的93例完全性前置胎盘引产晚期妊妇的临床资料。根据治疗方法的不同分为对照组和观察组。对照组采用双侧子宫动脉栓塞联合依沙吖啶和米非司酮引产;观察组在对照组基础上加用甲氨蝶呤引产。比较两组妊妇临产时间、产时出血量、产后出血量、住院时间、恶露时间、月经恢复时间、引产成功率、子宫切除率、清宫率及术后并发症。【结果】 观察组产时出血量、产后出血量及住院时间显著低于对照组(P<0.05);而两组的临产时间、恶露持续时间、月经恢复时间、引产成功率、子宫切除率及清宫率比较差异均无统计学意义(P>0.05)。观察组术后并发症总发生率为23.33%,与对照组的24.24%比较差异无统计学意义(P>0.05)。【结论】 子宫动脉栓塞术联合甲氨蝶呤、依沙吖啶和米非司酮应用于晚期完全性前置胎盘引产,能减少患者产时、产后出血量,缩短住院时间,且不增加不良反应并发症发生率,值得临床推广应用。
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王静
卢英
杨雪琴
关键词 前置胎盘引产栓塞,治疗性甲氨蝶呤/治疗应用    
Abstract:【Objective】To investigate the effect of uterine artery embolization combined with methotrexate, ethacridine and mifepristone in induced labor of pregnant women with complete placenta previa. 【Methods】The clinical data of 93 pregnant women with complete placenta previa induced labor in our hospital from March 2014 to March 2018 were retrospectively analyzed. According to the different treatment methods, they were divided into control group and observation group. The control group was induced by bilateral uterine artery embolization combined with ethacridine and mifepristone; the observation group was induced by methotrexate on the basis of the control group. The time of labor, the amount of bleeding during labor, the amount of postpartum hemorrhage, hospitalization time, lochia time, menstrual recovery time, success rate of induced labor, hysterectomy rate, curettage rate and postoperative complications were compared between the two groups. 【Results】The amount of intrapartum hemorrhage, postpartum hemorrhage and hospitalization time in the observation group were significantly lower than those in the control group (P<0.05); however, there was no significant difference in the labor time, lochia duration, menstrual recovery time, induced labor success rate, hysterectomy rate and uterine curettage rate between the two groups (P>0.05). The total incidence of postoperative complications in the observation group was 23.33%, which was not significantly different from 24.24% in the control group (P>0.05). 【Conclusion】Uterine artery embolization combined with methotrexate, ethacridine and mifepristone in the induction of labor of late complete placenta previa can reduce the amount of bleeding during labor and postpartum, shorten the hospitalization time, and does not increase the incidence of adverse reactions and complications, which is worthy of clinical application.
Key wordsPlacenta Previa    Labor,In-duced    Embolization,therapeutic    Methotrexate/TU
收稿日期: 2019-01-27     
PACS:  R714.56  
引用本文:   
王静, 卢英, 杨雪琴. 子宫动脉栓塞联合甲氨蝶呤、依沙吖啶和米非司酮在晚期完全性前置胎盘引产中的应用[J]. 医学临床研究, 2020, 37(6): 895-897.
WANG Jing, LU Ying, YANG Xue-qin. Application of Uterine Artery Embolization Combined with Methotrexate, Ethacridine and Mifepristone in Induction of Labor in Late Complete Placenta Previa. JOURNAL OF CLINICAL RESEARCH, 2020, 37(6): 895-897.
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http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2020.06.029     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2020/V37/I6/895
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