Therapeutic Effect of Meglumine Adenosine Cyclophosphat Combined with Musk Baoxin Pill on the Treatment of Chronic Pulmonary Heart Disease with Heart Failure
Abstract：【Objective】To observe the efficacy of meglumine adenosine cyclophosphat combined with musk Baoxin pill on the treatment of chronic pulmonary heart disease with heart failure. 【Methods】A total of 110 patients with chronic pulmonary heart disease and heart failure were enrolled. According to the random number table method, the patients were divided into the observation group (55 cases, with treatment of meglumine adenosine cyclophosphat combined with musk Baoxin pill) and the control group (55 cases, with meglumine adenosine cyclophosphat treatment only). Lung function indexes (FEV1, FEV1/FVC), blood gas analysis indexes (SaO2, PaO2), cardiac function indicators (LVEF, LVD, CO, LVS) before and after treatment were analyzed. The efficacy, occurrence of adverse drug reactions, and the mortality within 14 days were observed. 【Results】The total effective rate of the observation group at the end of treatment was 96.36%, which was higher than that of the control group (83.64%), the difference was statistically significant (χ2=4.946,P=0.026). After treatment, the parameters of SaO2, PaO2, FEV1 and FEV1/FVC in the two groups were higher than those before treatment. Of which, the SaO2, PaO2 in the control group were higher than those in the observation group; and the difference was statistically significant (P<0.05). However, there were no significant differences in FEV1 and FEV1/FVC between the two groups after treatment (P>0.05). The LVEF of the control group after the treatment was higher than that before treatment, while both LVD and LVS of the observation group were lower than those of the control group, the differences were statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions and mortality rate between the control group and the observation group (P>0.05). 【Conclusion】Meglumine adenosine cyclophosphat combined with musk Baoxin pill has good clinical effect on the treatment of chronic pulmonary heart disease with heart failure, which improves the cardiac function and blood gas analysis indicators and reduces pulmonary artery pressure safely.
刘雪娇. 环磷腺苷葡胺联合麝香保心丸治疗慢性肺源性心脏病合并心衰的疗效观察[J]. 医学临床研究, 2020, 37(6): 898-900.
LIU Xue-jiao. Therapeutic Effect of Meglumine Adenosine Cyclophosphat Combined with Musk Baoxin Pill on the Treatment of Chronic Pulmonary Heart Disease with Heart Failure. JOURNAL OF CLINICAL RESEARCH, 2020, 37(6): 898-900.
2020, Vol. 37 
