支架辅助弹簧圈栓塞治疗颅内大型或巨大型动脉瘤36例疗效观察

doi:10.3969/j.issn.1671-7171.2019.07.006

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摘要 【目的】探讨支架辅助弹簧圈栓塞在颅内大型或巨大型颅内动脉瘤治疗中的效果。【方法】回顾性研究本院收治的65例颅内大型或巨大型动脉瘤患者临床资料,根据治疗方法的不同将其分为观察组(支架辅助弹簧圈栓塞,n=36)和对照组(单纯弹簧圈栓塞,n=29)。比较两组术后栓塞程度,预后情况及术中并发症发生情况。【结果】观察组术后即刻栓塞程度Ⅰ级为61.11%,优于对照组的34.48%,差异有统计学意义(Z=-2.212,P=0.027＜0.05)。观察组mRS评分0～1分者23例(63.89%),对照组预后良好18例(62.07%),差异无统计学意义(χ²=0.023,P=0.88＞0.05)。应用Fisher检验分析,观察组术中动脉瘤再破裂,弹簧圈移位、脱出、解旋,动脉瘤缺血事件和脑血管痉挛发生率与对照组比较,差异无统计学意义(P>0.05)。【结论】支架辅助弹簧圈栓塞在颅内大型或巨大型颅内动脉瘤治疗中有较好的临床效果,安全性较好,值得临床推广应用。

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	马传钰
	刘建仁

关键词 ：颅内动脉瘤/外科学, 栓塞, 治疗性

Abstract：【Objective】To investigate the effect of stent-assisted coil embolization in the treatment of large or giant intracranial aneurysms. 【Methods】The clinical data of 65 patients with large or giant intracranial aneurysms treated in our hospital were retrospectively studied. They were divided into observation group (stent-assisted coil embolization,n=36) and control group (simple coil embolization, n=29). The degree of embolism, prognosis and intraoperative complications were compared between the two groups.【Results】The degree of immediate embolization in the observation group was 61.11%, which was better than 34.48% in the control group (Z=2.212,P=0.027<0.05). There were 23 cases (63.89%) with mRS score of 0-1 in the observation group and 18 cases (62.07%) with good prognosis in the control group. There was no significant difference between the two groups (χ²=0.023,P=0.88>0.05). Fisher test analysis showed that there was no significant difference in aneurysm re-rupture, coil displacement, detachment and rotation, aneurysm ischemia and cerebral vasospasm between the observation group and the control group (P>0.05).【Conclusion】Stent-assisted coil embolization has good clinical effect and safety in the treatment of large or giant intracranial aneurysms, which is worthy of clinical application.

Key words： Intracranial Aneurysm/SU Embolization,Therapeutic

收稿日期: 2018-10-10

PACS:

R651.122

通讯作者: E-mail:liujianren999@163.com

引用本文:

马传钰, 刘建仁. 支架辅助弹簧圈栓塞治疗颅内大型或巨大型动脉瘤36例疗效观察[J]. 医学临床研究, 2019, 36(7): 1264-1266.
MA Chuan-yu, LIU Jian-ren. Effect of Stent-assisted Coil Embolization in the Treatment of Large or Giant Intracranial Aneurysms:36 Case Report. JOURNAL OF CLINICAL RESEARCH, 2019, 36(7): 1264-1266.

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http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2019.07.006 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2019/V36/I7/1264