Abstract：【Objective】 To investigate the clinical effect and survival rate of TPCE combined with CT guided percutaneous microwave ablation in the treatment of advanced non-small cell lung cancer (NSCLC).【Methods】 The clinical data of 116 patients with advanced lung cancer in our hospital were analyzed retrospectively. According to different treatment methods, they were divided into observation group and control group, 58 cases in each group. TPCE was given to the patients in the control group, and tpce combined with percutaneous microwave ablation (PMAT) was used in the observation group. Three months after treatment, contrast-enhanced CT was performed to compare the therapeutic effect of the two groups. Serum CEA, CA125 and VEGF levels were compared before and after treatment. The survival rates of 1,2,3 years were recorded.【Results】 The disease control rate of the observation group was 84.5% (49 / 58), higher than that of the control group (67.2%) (39 / 58), the difference was statistically significant (χ2=4.708,P<0.05). Three months after treatment, the serum CEA, CA125 and VEGF levels of the two groups decreased, and the difference was statistically significant (P<0.05). The 1,2,3-year survival rate in the observation group was significantly higher than that in the control group (P<0.05).【Conclusion】 TPCET combined with PMAT sequential treatment can significantly improve the therapeutic effect of NSCLC and improve the survival rate of patients.
2020, Vol. 37 
