Abstract:【Objective】 To investigate the effect of radiofrequency ablation (RFA) on cardiac function and quality of life in patients with atrial fibrillation. 【Methods】 A total of 112 patients with atrial fibrillation in our hospital from December 2016 to March 2018 was selected and divided into drug group and RFA group according to different treatment methods. Patients in the control group were treated with drugs, while patients in the observation group were treated with RFA. The cardiac function indexes before and 3 months after treatment were compared between the two groups, and the quality of life of the two groups before and after 3 months of treatment was analyzed. 【Results】 After treatment, the maximum value of left atrial volume index (LAVImax) and minimum left atrial volume index(LAVImin)of the observation group were lower than those of the control group, and the left ventricular ejection fraction (LVEF) was higher than that of the control group, the difference was statistically significant (P<0.05); but there was no significant difference in the level of left ventricular diameter (LVD) between the observation group and the control group (P>0.05). Before treatment, there was no significant difference in quality of life scores between the two groups (P>0.05). After treatment, the scores of general health and quality of life in the observation group were higher than those in the control group, the difference was statistically significant (P<0.05), but there was no significant difference in the scores of mental health, social function and independent living ability between the two groups (P>0.05).【Conclusion】 RFA in the treatment of atrial fibrillation can improve the cardiac function, improve the general health and quality of life of patients, which is worthy of clinical reference.
董国政, 马鹏飞. 射频消融治疗房颤对患者心功能及生活质量的影响[J]. 医学临床研究, 2020, 37(7): 1036-1038.
DONG Guo-zheng, MA Peng-fei. Effect of Radiofrequency Ablation on Cardiac Function and Quality of Life in Patients with Atrial Fibrillation. JOURNAL OF CLINICAL RESEARCH, 2020, 37(7): 1036-1038.
[1] 龙汉春,彭国光,陈映,等.心房颤动对不同治疗时机下脑梗死患者静脉溶栓效果影响的研究[J].中国现代医学杂志,2016,26(4):104-107. [2] Sandhu RK,Smigorowsky M,Lockwood E,et al.Impact of electrical cardioversion on quality of life for the treatment of atrial fibrillation[J].Can J Cardiol,2017,33(4):450-455. [3] 张源,王君,汪智全,等.心房颤动患者射频消融术后3个月生活质量及影响因素分析[J].中国介入心脏病学杂志,2017,25(8):447-451. [4] 袁鹏,毕齐.心房颤动射频消融术术后并发急性缺血性脑卒中临床研究[J].心肺血管病杂志,2016,35(5):357-361. [5] Allan KS,Henry S,Aves T,et al.Comparison of health-related quality of life in patients with atrial fibrillation treated with catheter ablation or antiarrhythmic drug therapy: a systematic review and meta-analysis protocol[J].BMJ Open,2017,14(1):65. [6] 蔡谦谦,李天成,周蓉,等.冷冻球囊消融与射频消融治疗阵发性心房颤动效果Meta分析[J].介入放射学杂志,2017,26(2):109-113. [7] Lopes MRS,Lucas B,Enia C,et al.Reproducibility and reliability of the quality of life questionnaire in patients with atrial fibrillation[J].Arq Bras Cardiol,2016,106(3):171-181. [8] 白英,吴佳慧,刘心遥,等.EHRA症状分层对低CHADS2评分心房颤动患者射频消融术后生活质量改善中的预测价值[J].中华心律失常学杂志,2016,20(2):135-139. [9] Cherian TS,Shrader P,Fonarow GC,et al.Effect of atrial fibrillation on mortality,stroke risk,and quality-of-life scores in patients with heart failure (from the outcomes registry for better informed treatment of atrial fibrillation [ORBIT-AF])[J].Am J Cardiol,2017,119(11):1763. [10] 白英,刘念,白融,等.心房颤动射频消融术对低CHA2DS2-VASc评分心房颤动患者生活质量的影响[J].中华内科杂志,2016,55(4):278-282. [11] 周小明,夏小艳.环肺静脉隔离联合左心房顶部线性的疗效观察消融术治疗阵发性房颤的疗效观察[J].医学临床研究,2019,36(11):2232-2234.