Abstract：【Objective】 To explore effects of remifentanil on anesthesia, sedation score (Ramsay score) and visual analogue score (VAS score) in pregnant women undergoing caesarean section.【Methods】 A total of 100 cases of caesarean section pregnant women were randomly divided into two groups. Remifentanil anesthesia was used in the observation group and the conventional anesthesia was used in the control group. The anesthesia effect, Ramsay score, VAS score and postoperative recovery of the two methods were compared between the two groups. 【Results】 The excellent and good rate of the observation group was 98% (49/50), which was higher than that of the control group 86% (43/50).The difference was statistically significant (P<0.05). There was no significant difference between the two groups in the immediate postoperative Ramsay score and VAS score (P>0.05). However, both Ramsay score and VAS score at 24 hours after operation in the observation group were significantly better than those in the control group (P<0.05). The neonatal arterial blood gas indicators did not show any significant difference between the two groups. Three women in the observation group had nausea and vomiting, the incidence rate was 6% (3/50), and two patients in the control group had nausea and vomiting, the incidence rate was 4% (2/50). There was no significant difference between the two groups (P>0.05).【Conclusion】 Remifentanil has better anesthetic effect on caesarean section patients, which can effectively reduce the pain of patients and has no significant effect on the blood gas of newborns. Thus it is worthy of further clinical promotion.
谢景连. 瑞芬太尼对剖腹产孕妇的麻醉效果及镇静评分和 VAS评分的影响[J]. 医学临床研究, 2020, 37(7): 1033-1035.
XIE Jing-lian. Effects of Remifentanil on Anesthesia, Ramsay score and VAS score in Pregnant Women undergoing Caesarean Section. JOURNAL OF CLINICAL RESEARCH, 2020, 37(7): 1033-1035.
[1] 杨静,张丽,刘丽,等.瑞芬太尼自控镇痛联合导乐仪用于产妇分娩镇痛的效果[J].中国临床研究,2017,30(11):1539-1541. [2] 赵俊莺,王武涛,舒雅,等.不同麻醉方案用于剖宫产对产妇炎症因子和应激反应的影响[J].基因组学与应用生物学,2018,37(4):1792-1798. [3] Choi EK,Seo Y,Dong GL,et al.Postoperative nausea and vomiting after thyroidectomy: a comparison between dexmedetomidine and remifentanil as part of balanced anesthesia[J].Korean J Anesth,2017,70(3):299-304. [4] 陈莹莹,夏晓琼,陶志国,等.超声引导下腹部神经阻滞联合瑞芬太尼输注在血小板减少产妇剖宫产手术中的应用[J].临床麻醉学杂志,2017,33(10):980-983. [5] Mita K,Tsugita K,Yasuda Y,et al.A successfully treated case of cardiac arrest after Caesarean section complicated by pheochromocytoma crisis and amniotic fluid embolism[J].J Anesth,2017,31(1):140-143. [6] Mahajan L,Mittal V,Gupta R,et al.Study to compare the effect of oral,rectal,and intravenous infusion of paracetamol for postoperative analgesia in women undergoing cesarean section under spinal anesthesia[J].Anesth Essays Res,2017,11(3):594-598. [7] 徐光红,李珺.小剂量瑞芬太尼复合丙泊酚联合喉罩通气在剖宫产术中的应用[J].实用医学杂志,2018,34(5):824-827. [9] 张平.瑞芬太尼靶控输注用于剖宫产全麻诱导及维持对产妇及新生儿的影响[J].陕西医学杂志,2017,46(2):252-254. [10] Kart K,Hanci A.Effects of remifentanil and dexmedetomidine on the mother's awareness and neonatal Apgar scores in caesarean section under general anaesthesia[J].J Int Med Res,2018,46(5):1846-1854. [11] 曾渊,杭博,蒯建科,等.再次剖宫产术产妇硬膜外麻醉中应用右美托咪定静脉输注与硬膜外注射麻醉效果对比研究[J].陕西医学杂志,2018,47(12):1544-1547.
2020, Vol. 37 
