Abstract：【Objective】 To compare the effect of enteral nutrition at different time on severe acute pancreatitis (SAP).【Methods】 One hundred and three patients with SAP in our hospital were randomly divided into early enteral nutrition group (EEN group,n=53) and delayed enteral nutrition group (DEN group,n=50). Enteral nutrition was started at 48 hours in the EEN group and 96 hours in the DEN group. The hospitalization time, abdominal pain relief time and spontaneous defecation time, mortality and complications of the EEN group and the DEN group were compared. The changes of nutritional indexes (albumin, prealbumin) and inflammatory indexes (C-reactive protein and procalcitonin) in peripheral blood of the two groups on the day 14th were compared.【Results】 The time of abdominal pain relief, the time of spontaneous defecation and the mortality rate during hospitalization in the EEN group were lower than those in the DEN group (P<0.05). The incidence of systemic inflammatory response syndrome (SIRS), intra-abdominal hypertension and pancreatic abscess complications in the EEN group was lower than that in the DEN group (P<0.05). Ten days after admission, the levels of albumin and prealbumin in the EEN group were lower than those in the DEN group, the difference was statistically significant (P<0.05); there was no significant difference in peripheral blood inflammatory indexes (C-reactive protein, procalcitonin) between the two groups (P>0.05).【Conclusion】 Early enteral nutrition support is conducive to the recovery of SAP patients, and can reduce the mortality and some complications.
毕宁, 王菁, 陈会. 不同时机肠内营养对重症急性胰腺炎治疗效果分析[J]. 医学临床研究, 2020, 37(7): 1030-1032.
BI Ning, WANG Jing, CHEN Hui. Effect of Different Time Enteral Nutrition on Severe Acute Pancreatitis. JOURNAL OF CLINICAL RESEARCH, 2020, 37(7): 1030-1032.
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2020, Vol. 37 
