Abstract：【Objective】 To explore the effects of nabocone hydrochloride on sedation, analgesia and negative emotions after cesarean section in women. 【Methods】 A total of 128 patients of full-term pregnant women who received cesarean section in our hospital were selected and randomly divided into two groups. There were 64 cases in the observation group who received intravenous injection of nabocone hydrochloride, while 64 cases in the control group received intravenous sufentanil analgesia. The sedative and analgesic effects of the two groups were observed and compared. The degree of postpartum depression of the two groups were measured and compared as well, while the total incidence of adverse reactions was calculated. 【Results】 The analgesic scores of 6h, 12h and 24h in the observation group were significantly lower than those in the control group; and the sedation score in the observation group was also lower than that in the control group. The difference between the two groups was significant (P<0.05). There was no significant difference in the antenatal depression score between the two groups (P>0.05). The postpartum depression score of the observation group 3 days after delivery in the observation group was significantly lower than that in the control group (P<0.05). The total postpartum depression rate in the observation group was7.81% which was significantly lower than that of the control group (23.44%, P<0.05). The incidence of adverse reactions in the observation group was 11.76% (8/64), which was significantly lower than that in the control group (59.38%, 38/64). The difference between the two groups was statistically significant (P<0.05). 【Conclusion】 Nabocone hydrochloride injection has a good effect on postoperative analgesia and sedation in cesarean parturients, the possibility of postpartum depression and the incidence of adverse reactions are low. It is suitable for clinical popularization.
李世红, 邓红燕, 牟俊杰. 盐酸纳布啡注射液对剖宫产手术后镇静镇痛效果及负性情绪的影响[J]. 医学临床研究, 2020, 37(4): 536-538.
LI Shi-hong, DENG Hong-yan, MOU Jun-jie. Effects of Nabocone Injection on Sedation, Analgesia and Negative Emotions after Cesarean Section. JOURNAL OF CLINICAL RESEARCH, 2020, 37(4): 536-538.
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2020, Vol. 37 
