医学临床研究
  2025年7月20日 星期日           首 页    |    期刊简介    |    编委会    |    投稿指南    |    期刊订阅    |    广告合作    |    留言板    |    联系我们    |    English
医学临床研究  2020, Vol. 37 Issue (5): 708-711    DOI: 10.3969/j.issn.1671-7171.2020.05.022
  论著 本期目录 | 过刊浏览 | 高级检索 |
腹腔镜子宫肌瘤切除术术后行舒芬太尼靶控镇痛的效果及对患者应激反应、免疫功能的影响
廖海明1, 余凡2, 邓庆珊2, 廖家齐1
1.南方医科大学第三附属医院麻醉科,广东 广州 510000;
2.广东省妇幼保健院妇科,广东 广州 510000
Effect of Sufentanil Target-Controlled Infusion on Postoperative Analgesia, Stress Response and Immune Function after Laparoscopic Surgery
LIAO Hai-ming, YU Fan, DENG Qing-shan, et al
Department of Anesthesiology, Southern Medical University,Guangzhou 510000
全文: PDF (0 KB)   HTML (1 KB) 
输出: BibTeX | EndNote (RIS)      
摘要 【目的】 探讨腹腔镜子宫肌瘤切除术术后患者行舒芬太尼靶控镇痛的效果及对术后应激反应、免疫功能的影响。【方法】 本院行腹腔镜手术患者82例,随机分为对照组(n=42)和观察组(n=40),对照组术后使用静脉途径镇痛,观察组使用枸橼酸舒芬太尼靶控镇痛。比较术后两组患者镇静、镇痛评分情况以及治疗前后P物质和β内啡肽浓度和CD4+、CD8+、CD4+/CD8+水平差异。【结果】 术后两组患者镇痛和镇静评分相比较差异均有显著性(P<0.05)。 治疗后观察组的P物质浓度水平显著低于,内啡肽浓度水平显著高于治疗前和同期对照组,且差异具有显著性(P<0.05)。治疗后观察组的CD4+ 水平显著低于治疗前和同期对照组(P<0.05),治疗后两组间的CD8+ 和CD4+/CD8+水平相比较差异无显著性(P>0.05)。【结论】 腹腔镜子宫肌瘤切除术术后患者行舒芬太尼靶控镇痛,其镇痛和镇静效果好于静脉输注组,且可降低患者的术后应激反应和调节免疫功能,值得临床上进一步推广。
服务
把本文推荐给朋友
加入我的书架
加入引用管理器
E-mail Alert
RSS
作者相关文章
廖海明
余凡
邓庆珊
廖家齐
关键词 腹腔镜检查舒芬太尼/治疗应用镇痛    
Abstract【Objective】 To investigate the effect of sufentanil target-controlled infusion on postoperative analgesia, stress response and immune function after laparoscopic surgery. 【Methods】 A total of 82 patients with laparoscopic surgeries in our hospital were collected in the study. The randomized digital table was used to divide these cases into the control group (n=42) and the observation group (n=40). Patients in the control group received intravenous analgesia after operation, while patients in the observation group received the target-controlled analgesic of citrate sufentanil after operation. The postoperative sedation and analgesia scores of the two groups were compared, meanwhile, the concentrations of substance P and β endorphin and levels of CD4+, CD8+, CD4+/CD8+ were measured before and after treatment.【Results】 The analgesia and sedation scores between the two groups had significant difference (P<0.05). After treatment, the level of substance P in the observation group was significantly lower, while the level of β-endorphin in the observation group was higher than that in the control group and before treatment (P<0.05). The level of CD4+ in observation group after treatment was lower than that before treatment, and the CD4+ level in the observation group was also lower than that in the control group (P<0.05). The levels of CD8+ and CD4+/CD8+ had no significant difference between the two groups (P>0.05). 【Conclusion】 The application of the sufentanil target-controlled infusion shows good postoperative analgesia effect, which reduces the postoperative stress response and immune function regulation for patients after laparoscopic surgery. It is worthy of further clinical promotion.
Key wordsLapa-roscopy    Sufentanil/TU    Analgesia
收稿日期: 2018-10-25     
PACS:  R61  
引用本文:   
廖海明, 余凡, 邓庆珊, 廖家齐. 腹腔镜子宫肌瘤切除术术后行舒芬太尼靶控镇痛的效果及对患者应激反应、免疫功能的影响[J]. 医学临床研究, 2020, 37(5): 708-711.
LIAO Hai-ming, YU Fan, DENG Qing-shan, et al. Effect of Sufentanil Target-Controlled Infusion on Postoperative Analgesia, Stress Response and Immune Function after Laparoscopic Surgery. JOURNAL OF CLINICAL RESEARCH, 2020, 37(5): 708-711.
链接本文:  
http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2020.05.022     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2020/V37/I5/708
版权所有 © 2013 医学临床研究杂志社  湘ICP备13012052号-1
办公地址:湖南省长沙市芙蓉区新军路43号煤炭大院主办公楼6楼621、623、632、636室 邮编:410011 电话(传真):0731-84824007 E-mail:jcr_cs.hn@vip.163.com
技术支持:北京玛格泰克科技发展有限公司 技术支持:support@magtech.com.cn