Effect of Ultrasound-guided Horizontal Abdominal Muscle Block on Preventive Analgesia and Inflammatory Factors in Patients Undergoing Gynecological Laparoscopic Surgery
ZHAO Wang-cheng, YAN Jun
Department of Anesthesiology, Shaanxi Province Hanzhong 321 Hospital,Hanzhong Shaanxi 723000
Abstract:【Objective】 To observe the effect of ultrasound-guided transverse abdominal muscle block on preventive analgesia and inflammatory factors in patients undergoing gynecological laparoscopic surgery. 【Methods】 From February 2016 to January 2018, 120 patients undergoing gynecological laparoscopic surgery were randomly divided into observation group (n=60) and control group (n=60).The observation group underwent ultrasound-guided abdominal transverse muscle plane block anesthesia before anesthesia, while the control group underwent ultrasound-guided abdominal transverse muscle plane block anesthesia after operation. The pain status (pain VAS score),analgesic recovery rate, comfort scale (BCS) score and inflammatory factors (tumor necrosis factor-α, IL-6, IL-2, IL-8 and postoperative infection) levels of the two groups at different time points were compared.【Results】 The rest and exercise VAS scores of the patients in the observation group were significantly lower than 1 h after operation (P<0.05); the VAS scores of the patients in the control group at different time points after operation were significantly lower than those in the control group (P<0.01). The postoperative remediation rate (1.67%) in the observation group was significantly lower than that in the control group (11.67%)(P<0.05); the BCS score in the observation group was significantly lower than that in the control group at different time points after operation (P<0.05); and the TNF-α、IL-6、IL-2、IL-8 level in the observation group was significantly lower than that in the control group at 24 h after operation (P<0.05). 【Conclusion】 The use of ultrasound-guided horizontal abdominal muscle block before anesthesia in gynecological laparoscopic surgery can effectively play a preventive analgesic role, reduce the level of postoperative inflammatory factors, and promote the postoperative rehabilitation of gynecological laparoscopic surgery patients.