Abstract：【Objective】To study the clinical effect of drug-eluting balloon (DEB) in the treatment of ISR after percutaneous coronary intervention (PCI) in patients with coronary heart disease.【Methods】The clinical data of 50 patients with coronary heart disease treated by ISR from January 2012 to May 2017 were analyzed retrospectively. According to the type of stent, it was divided into DES group and DEB group. The clinical features, coronary angiography features, and terminal events within 12 months after treatment were compared between the two groups.【Results】After 6 months of treatment, coronary angiography showed that the incidence of restenosis in the DEB group was significantly lower than that in the DES group (P<0.05).There was no significant difference in TIMI blood flow grade Ⅰ, Ⅱ, Ⅲ, stenosis degree, minimum lumen diameter and late lumen loss between the two groups (P>0.05). The incidence of secondary stent stenosis in the DES group was 24.00% (6 / 25), which was significantly higher than that in the DEB group (4.00%, 1 / 25). The difference was statistically significant(χ2=4.153,P=0.042<0.05). Kaplan-Meier survival analysis showed that there was no significant difference in MACE free survival rate between the two groups within 12 months after operation (χ2=0.467,P=0.494＞0.05). 【Conclusion】The clinical efficacy of DEB in the treatment of ISR is comparable to that of DES with high safety, and no serious complications such as artery laceration dissection have been caused.
邹永伟, 胡小恋. 药物洗脱球囊治疗冠心病患者PCI术后支架内再狭窄25例疗效观察[J]. 医学临床研究, 2018, 35(10): 1899-1901.
ZOU Yong-wei, HU Xiao-lian. Clinical Effect of Drug-Eluting Balloon in the Treatment of ISR after PCI in Patients with Coronary Heart Disease. JOURNAL OF CLINICAL RESEARCH, 2018, 35(10): 1899-1901.
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