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Quick Search     Adv Search 2015 Vol. 32, No. 9 Published: 2015-09-26   1665 Efficacy Comparison of Different MiniInvasive Lung Resections for Early NonSmall Cell Lung Cancer Hot! ZHANG Jin,SHI Zixia,ZHOU Renjie 【Objective】To compare the efficacies of lung resection and pulmonary wedge resection for early nonsmall cell lung cancer (NSCLC). 【Methods】 A total of 100 hospitalized NSCLC patients were recruited for lung resection between January 2008 and July 2014. They were divided randomly into two groups of lung resection and pulmonary wedge resection (n=50 each). And two groups were compared with regards to postoperative complications, followup recurrence and death. 【Results】 The hospitalization and operative durations of pulmonary wedge resection group were shorter than those of pulmonary resection group. And the differences had statistical significance (P<0.05). Indwelling drainage tube time, bleeding amount, complications, local recurrence, distant metastasis and death showed no intergroup statistical significance (P>0.05). 【Conclusion】 The efficacies of pulmonary resection and pulmonary wedge resection are similar for early NSCLC. 2015 Vol. 32 (9): 1665-1667 [Abstract] ( 37 ) HTML (1 KB)  PDF  (0 KB)  ( 32 ) 1668 A Comparative Study of Hepatic Arterial Chemoembolization and Chemotherapy Infusion in the Treatment of Hepatic Metastasis Hot! LU Guilong REN Qingyun 【Objective】To compare the efficiency and the longterm survival rate of patients with liver metastasis treated by hepatic arterial chemoembolization and hepatic arterial chemotherapy infusion. 【Methods】89 patients with liver metastasis were divided into the observation group and the control group for a retrospective study . The control group of patients had 41 cases, and the observation group 48 cases. The control group was treated with hepatic arterial infusion, and the observation group with hepatic arterial chemoembolization. The effects of two kinds of treatment on liver function, tumor volume, adverse reactions and complications were observed and compared.【Results】The longest diameter of the tumor of the observation group was decreased to (3.06±0.75)cm post operation from (5.17±1.03)cm. and that of the control group was decreased to (4.51±0.61)cm from (5.33±1.15)cm, the effect of the observation group was better than that of the control group; 6 months after operation, the efficacy of the observation group was 64.6%, higher than that of the control group 36.6%, There was no significant difference in the incidence of complications among the two groups, and the survival rate of 12 months after operation of the observation group was significantly higher than that of the control group; And the survival rate of 6 months of the two groups had no obvious difference.【Conclusion】Hepatic arterial chemoembolization and chemotherapy infusion can effectively control and reduce the liver metastasis, but the efficacy ,the relaxing rate and survival rate of patients underwent hepatic arterial chemoembolization are much better than those treated by chemotherapy infusion, thus it is worthy of clinical promotion. 2015 Vol. 32 (9): 1668-1673 [Abstract] ( 45 ) HTML (1 KB)  PDF  (0 KB)  ( 49 ) 1670 Effect of Different Head Position in Endotracheal Intubation Assisted with Macintosh Laryngoscope ZHAO Hongxia LIU Hongtao WANG Tenghuan et al 【Objective】 To discuss the difference of the pharyngeal stimulation at endotracheal intubation assisted with the Macintosh laryngoscope through a simple head hypsokinesis , or modifying the position of laryngeal lens,.【Methods】864 patients aged between 15~72 at ASAⅠ~Ⅱ were chosen, who would take endotracheal intubation under general anesthetic and have non laryngeal operation. Patients were randomly divided into the head back group (group S) and the laryngeal lens modification group( group C). The Cormack and Lehane glottal exposure classification and successful intubation time were recorded and compared, which performed by formally trained anesthesiologists who used the same specifications of the Macintosh laryngoscope with a simple head hypsokinesis or modification of laryngoscope lens.【 Results】1 .The time of successful intubation in group S was shorter than that in group C, and the difference between the two groups was significant (P<0.05); 2. The Cormack and Lehane level in group S is higher than that in group C , and the difference was significant (P<0.05); 3. In the next day's pharyngoscope testing, the pharyngeal injuries in group S were serious and mainly concentrated in the lingual surface of epiglottis , while those in group C were mild and mainly concentrated in pharyngeal arch ; 4. The incidence of pharyngeal hemorrhage and tooth loss in the group S were higher than those in group C (P<0.05); The two groups had no sequelae of spinal cord injury.【Conclusion】 With the assistance of the Macintosh laryngoscope, a simple head hypsokinesis at endotracheal intubation takes less time than laryngeal lens modification, but pharyngeal stimulation is heavier and the incidence of complications are higher. 2015 Vol. 32 (9): 1670-1673 [Abstract] ( 76 ) HTML (1 KB)  PDF  (0 KB)  ( 41 ) 1674 Prediction Value of HBsAg and HBeAg in the Therapeutic Effect of Interferon on HBeAg Positive Chronic Hepatitis B XIAO Hong SUN Hongqing YANG Fei et al 【Objective】To investigate the dynamic changes of serum hepatitis B surface antigen (HBsAg) and hepatitis B virus e antigen (HBeAg) levels for the prediction of the therapeutic effect of interferon on HBeAg positive chronic hepatitis B. 【Methods】The clinical data of 47 patients with chronic hepatitis B treated by(PEGIFNα2a in the Public Health Center of Shanghai were analyzed retrospectively. Treatment:48～72 weeks, once/week,180μg,24 weeks of followup after treatment. According to the criteria for sustained viral response (SVR), patients were divided into the SVR group and the non SVR group. The levels of serum HBsAg and HBeAg of pretreatment, 12 weeks and 24 weeks post treatment were detected respectively, and the dynamic changes of the related indexes of the two groups were observed.【Results】In the twelfth week of treatment and 24week followup ,the level of serum HBeAg in patients of the SVR group was significantly lower than that in the non SVR group, the difference was statistically significant(P<0.05); In twentyfourth week of followup, the level of serum HBsAg of the SVR group was significantly lower than that in the non SVR group, the difference was statistically significant(P<0.05). The decreasing rate of serum HBeAg and HBsAg levels in the SVR group were significantly higher than those in the non SVR group, the difference was statistically significant (P<0.05). ROC curve analysis showed that the HBeAg level had the best predictive value at 24th week.【Conclusion】Both HBsAg and HBeAg have good predictive value on the efficacy of interferon, while HBeAg is better than HBsAg. 2015 Vol. 32 (9): 1674-1676 [Abstract] ( 106 ) HTML (1 KB)  PDF  (0 KB)  ( 39 ) 1677 Cardiovascular Rehabilitation Effect on Clinical Prognosis in Elderly Patients with Coronary Heart Disease Hot! YE Rongju WANG Kai 【Objective】To explore the effects of cardiovascular rehabilitation on clinical prognosis in elderly patients with coronary heart disease. 【Methods】60 cases of coronary heart disease aged patients were Selected and randomly divided into two groups the recovery group(with rehabilitation), and the control group (without rehabilitation treatment), 6 min after treatment, walking distance, BNP, LEFT, LVDd and ADL were compared betwent two groups . 【Results】After rehabilitation treatment, the treated group was significantly better than control group(P<0.05). 【Conclusion】Cardiovascular rehabilitation treatment for the clinical prognosis of elderly patients with coronary heart disease have a positive impact. 2015 Vol. 32 (9): 1677-1679 [Abstract] ( 66 ) HTML (1 KB)  PDF  (0 KB)  ( 32 ) 1679 Effect of Health Education on Metabolic Parameters in Patients with PreDiabetes Mellitus Hot! LI Wanju WANG Nana LI Min et al 【Objective】To observe the effect of the special education on the metabolic indexes of the patients with prediabetes in the early stage and the compliance by intervention.【Methods】On the base of health examination and diabetic clinic for the community residents, we screened a total of 138 cases of patients of prediabetes in accordance with standards whom were randomly assigned to the observation group (70 cases) and the control group (68 cases). After the implementation of health education in the observation group, we regularly followed up for 1 years. 【Results】The metabolic parameters, the incidence of prediabetes and the intervention compliance of the two groups were compared. The intervention compliance and prediabetes incidence of the observation group were significantly better than those in the control group (P<0.05). 【Conclusion】Health education can effectively improve the compliance of patients with prediabetes, reduce the incidence of prediabetes and metabolic index control. It is an effective method to prevent the development of prediabetes into diabetic mellitus. 2015 Vol. 32 (9): 1679-1681 [Abstract] ( 106 ) HTML (1 KB)  PDF  (0 KB)  ( 42 ) 1682 Clinical Significance of the Combined Detection of MG7Ag and TK1 in Gastric Cancer ZHANG Yuefan ZHANG Qiang YANG Youpeng et al 【Objective】To investigate the serum of gastric cancer associated antigen MG7Ag and thymidine kinase TK1 diagnostic value of combined detection of patients with gastric cancer.【Methods】Serum MG7Ag and TK1 levels were detected in 60 cases patients with gastric cancer (gastric cancer group), 35 cases of benign disease patients （benign disease group) and 30 healthy control subjects (healthy controls group).【Results】The serum of MG7Ag and TK1 levels in gastric cancer patients were higher than the healthy control subjects and benign gastric disease patients (both P<0.05); The positive detection rate of MG7Ag and TK1 in gastric cancer group were significantly higher than benign gastric disease group and the healthy control group (both P<0.05); Serum MG7Ag and TK1 joint detection sensitivity and accuracy were higher than the two separate detection indicator (both P<0.05).【Conclusion】Serum MG7Ag、TK1 has a high diagnostic value of gastric cancer, combined detection helps to improve the sensitivity and accuracy of diagnosis of gastric cancer. 2015 Vol. 32 (9): 1682-1684 [Abstract] ( 88 ) HTML (1 KB)  PDF  (0 KB)  ( 35 ) 1685 Protective Role of Ulinastatin Plus Shenfu Injection on Myocardial Injury in Severe Sepsis Patients LIU Dan LIU Hanzhe ZHOU Xiuhua 【Objective】 To explore the protective role of ulinastatin plus Shenfu Injection on myocardial injury in severe septic patients. 【Methods】 A total of 70 patients with sepsis and myocardial injury whose APACHEⅡscores ≥15 were randomly divided into ulinastatin treatment group (control) and ulinastatin plus Shenfu Injection treatment group (observation). The control group received ulinastatin treatment for 7 days while ulinastatin plus Shenfu Injection for 7 days in the observation group. Plasma NTproBNP level, serum troponin I (cTnI) level, cardiac index (CI) and APACHEⅡscores of patients were detected and evaluated at Day 1, 3 & 7 posttreatment. 【Results】 No significant intergroup differences existed in plasma NTproBNP level, serum cTnI level, CI and APACHEⅡscores at Day 1 after treatment (P>0.05). The levels of plasma NTproBNP and serum cTnI were significantly lower and the level of cardiac index was significantly higher than control group at Days 3 and 7 posttreatment (P<0.05). 【Conclusion】 Ulinastatin plus Shenfu Injection offers more benefits by energizing impaired myocardial cell directly. 2015 Vol. 32 (9): 1685-1687 [Abstract] ( 96 ) HTML (1 KB)  PDF  (0 KB)  ( 32 ) 1688 Advantages and Disadvantages of Two Nutrition Passages and Nursing Strategy in Severe Head Injury Patients LIU Fei HE Yuni XIAO Yicai et al 【Objective】To compare the advantages and disadvantages between nasogastric tube and gastrojejunostomy tube which was placed by percutaneous endoscopic gastrostomy (PEG) in severe head injury patients and to discuss the importance of appropriate nursing in patients with these two nutrition tubes.【Methods】Through detail analysis of the nutrient intake in 84 patients with severe head injury, the daily actual enteral nutrition value, complications, and accept index were compared between nasogastric tube and gastrojejunostomy tube.【Results】Actual enteral nutrition value is better in gastrojejunostomy tube group than nasogastric tube group. The gastrojejunostomy tube group has some surgical complications. The incidence of diarrhea is higher, while the incidence of gastric Dyskinesia is lower in Gastrojejunostomy tube group than nasogastric tube group. Nasogastric tube group has a better accept index than gastrojejunostomy tube group. 【Conclusion】The nutrition effects by gastrojejunostomy tube is better than nasogastric tube. Both methods have disadvantages and advantages. Appropriate nursing may overcome their shortcomings. 2015 Vol. 32 (9): 1688-1690 [Abstract] ( 93 ) HTML (1 KB)  PDF  (0 KB)  ( 38 ) 1691 Correlation Between Homocysteine, Uric Acid Level and Different Gender Patients with Unstable Angina Pectoris Hot! WU Lin CHEN Suxin XUE Zheng et al 【Objective】To investigate the correlation between homocysteine (Hcy), uric acid (UA) level and different gender patients with unstable angina pectoris (UAP). 【Methods】276 cases of patients with UAP in our hospital were divided into male UAP group (154 cases) and female UAP group (122 cases). Another 160 cases of people who received coronary angiogram inspection and were diagnosed without coronary heart disease were used as control group, including male control group (82 cases) and female control group (78 cases). The general data were analyzed. 【Results】There were significant difference in smoking, high density lipoprotein cholesterol (HDL), Hcy, vitamin B12 (Vit B12) and folic acid (FA) between male UAP group and male control group (P<0.05 or P<0.01). There were significant difference in high blood pressure, diabetes, UA, Hcy, Vit B12 and FA between female UAP group and female control group (P<0.05 or P<0.01). Logistic regression analysis showed that smoking, high blood pressure, HDL, Hcy and Vit B12 were independent risk factors of male UAP (P<0.05 or P<0.01); high blood pressure, UA, Hcy and Vit B12were independent risk factors of female UAP (P<0.05 or P<0.01). 【Conclusion】UA and Hcy are independent risk factors of female UAP; Hcy is independent risk factor of male UAP, not for UA.  2015 Vol. 32 (9): 1691-1698 [Abstract] ( 108 ) HTML (1 KB)  PDF  (0 KB)  ( 42 ) 1694 Clinical Application of Independently and Individually Designed Cutting Template in Primary Total Knee Arthroplasty Hot! LIU Wenqian LEI Qing CHEN Song et al 【Objective】To explore the feasibility and efficacy of independently designed individualized cutting template in primary total knee arthroplasty provide a novel reference for the bonecutting of total knee arthroplasty.【Methods】From September 2013 to December 2014, patients with initial knee osteoarthritis underwent total knee arthroplasty were randomly divided into Group A (the template group)and Group B(the control group). The individualized 3D printing osteotomy template which was independently designed was adopted by Group A .Group B (the control group) used the conventional cutting tools for surgery. The knee HSS(Hospital for Special Surgery) score( 3 months after surgery), the operation time, preoperative blood loss and postoperative lower limb force line of the two groups were recorded and compared .【Results】The preoperative blood loss in the group A was lower than that in the B group, but the difference was not statistically significant. Compared with group A, the operation time was longer in group B, and the mechanical axis of the lower limb force line was more than that of the neutral position, and the HSS score in group B was higher than in group A in 3month followup. 【Conclusion】 Although the postoperative longterm results are not yet known, the individual use of osteotomy template can simplify operation steps, shorten the operation time and get more satisfied lower limb force line. It is recommended as a new method in total knee arthroplasty. 2015 Vol. 32 (9): 1694-1698 [Abstract] ( 108 ) HTML (1 KB)  PDF  (0 KB)  ( 30 ) 1699 Ultrasound Findings and Clinical Significance of Fetal Hydronephrosis Hot! 【Objective】 To preliminarily explore the ultrasound (US) findings and clinical significance of fetal hydronephrosis. 【Methods】 Between January 2013 and February 2014, the imaging findings and clinical presentations were retrospectively reviewed for 49 USdiagnosed cases of feta lhydronephrosis. 【Results】 Among 5 cases with pelvis anteroposterior diameter (PAPD) ≥ 15 mm, 4 were diagnosed as congenital stricture of ureter after delivery; among 8 cases with PAPD between 10~14 mm, one was diagnosed as congenital stricture of ureter after delivery; among 36 cases with PAPD between 4~9 mm, only one was diagnosed as ureterectasia. 【Conclusion】 Ultrasonic examination may detect feta lhydronephrosis readily and has important clinical prognostic significance. 2015 Vol. 32 (9): 1699-1700 [Abstract] ( 87 ) HTML (1 KB)  PDF  (0 KB)  ( 38 ) 1701 Effect of Felodipine Combined with Heparin on Vascular Crisis Prevention After Finger Replantation as well as on Angiogenesis and Rheology Hot! DING Junjie ZHOU Lina GAO Hui,et al 【Objective】To explore the effect of Felodipine combined with Heparin on vascular crisis prevention after finger replantation as well as on angiogenesis and rheology【Methods】A total of 70 cases of finger replantation patients treated in our hospital from July 2014 to July 2012 were randomly divided into the observation group 35 cases and the control group 35 cases.The control group was treated with the conventional theraoy, and the observation group was given felodipine combined with low molecular weight heparin based on those of the control group; Operation information in general ,the incidence of vascular crisis and blood rheological indexes before and after the treatment were observed and compared between the two groups..Flow cytometry was used to detected the expression levels of bFGF and VEGF in the peripheral blood of the two groups before(T0) and after 6h (T1), 12h (T2),24h (T3), 48h (T4), 72h (T5), 120h (T6) surgery. 【Results】 There was no statistical difference in operation time between the two groups (P>0.05), the incidence of vascular crisis of the observation group 8.6% (8 / 35) was significantly lower than that of control group 28.6% (10 / 35), the difference was statistically significant (P<0.05). 1 week after treatment, the whole blood viscosity (WBV), plasma viscosity (PV), red blood cell settlement rate (ESR), blood cell hematocrit (HCT) of the two groups were significantly decreased , and the WBV, PV, ESR, HCT of the observation group after operation were significantly lower than those of the control group (P<0.05). The expression levels of bFGF and VEGF in the two groups began to increase after operation , and the expression of 48h VEGF and 72 h bFGF reached their peaks , then decreased gradually to the levels of 120h VEGF and 120h bFGF which were significantly higher than those before operation (P<0.05); and the expression level of bFGF and VEGF was significantly higher than that of the control group. The expression level of bFGF and VEGF in the observation group were significantly higher than those in the control group at the same time points, the difference was statistically significant (P<0.05).【Conclusion】Felodipine combined with heparin can effectively prevent the occurrence of vascular crisis after digital replantation, promote the angiogenesis, improve blood rheology and the success rate of replantation of amputated finger. 2015 Vol. 32 (9): 1701-1704 [Abstract] ( 85 ) HTML (1 KB)  PDF  (0 KB)  ( 34 )

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