医学临床研究
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医学临床研究  2025, Vol. 42 Issue (4): 612-614    DOI: 10.3969/j.issn.1671-7171.2025.04.015
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胎儿先天性肺囊腺瘤样畸形的产前超声特征及其对胎儿预后的影响
杨冬冬
商丘市妇幼保健院超声科,河南 商丘 476000
Prenatal Ultrasonic Features of Fetal Congenital Cystic Adenomatoid Malformation and their Impact on Fetal Prognosis
YANG Dongdong
Department of Ultrasound, Shangqiu Maternal and Child Health Care Hospital, Shangqiu Henan 476000
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摘要 【目的】探讨胎儿先天性肺囊腺瘤样畸形(congenital cystic adenomatoid malformation, CCAM)的产前超声特征及其对胎儿预后的影响。【方法】回顾性分析2021年1月至2023年12月在本院接受产前超声检查的52例CCAM胎儿,评估CCAM分型、超声特征、并发症发生情况及预后。【结果】52例CCAM胎儿中,大囊型(Ⅰ型)10例,中囊型(Ⅱ型)24例、微囊型(Ⅲ型)18例。产前超声特征:病变位于单侧48例,双侧4例;Ⅰ型~Ⅲ型CCAM体积比呈增大趋势(P<0.05),肺体积与胸廓体积比值呈降低趋势(P<0.05)。不同分型CCAM发生羊水过多及胎儿水肿、积液的情况比较,差异有统计学意义(P<0.05)。Ⅰ型~Ⅲ型CCAM引产率逐渐升高,不同分型CCAM引产率比较,差异有统计学意义(P<0.05)。CCAM胎儿随访发现,不同分型病灶体积变小占比比较,差异无统计学意义(P>0.05);Ⅰ型~Ⅲ型CCAM肺实变占比、有呼吸系统症状占比依次增大(P<0.05)。【结论】产前超声是鉴别胎儿CCAM的有效工具,对于预测疾病预后及改善新生儿的临床结局具有重要价值。
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杨冬冬
关键词 肺囊腺瘤样畸形 先天性胎儿超声检查 产前预后    
Abstract:【Objective】To explore the prenatal ultrasound characteristics of Congenital Cystic Adenomatoid Malformation (CCAM) in the fetus and its influence on the prognosis of the fetus. 【Methods】A retrospective analysis was conducted on 52 fetuses with CCAM who underwent prenatal ultrasound examinations in our hospital from January 2021 to December 2023. The classification of CCAM, ultrasound characteristics, occurrence of complications and prognosis were evaluated. 【Results】Among the 52 cases of CCAM, there were 10 cases of large cystic type (type Ⅰ), 24 cases of medium cystic type (type Ⅱ), and 18 cases of microcystic type (type Ⅲ). Prenatal ultrasound features: Lesions were located on one side in 48 cases and on both sides in 4 cases. The volume ratio of type Ⅰ to type Ⅲ CCAM showed an increasing trend (P<0.05), and the ratio of lung volume to thoracic volume showed a decreasing trend (P<0.05). There was a statistically significant difference in the occurrence of polyhydramnios and fetal edema and effusion among different types of CCAM (P<0.05). The induction rate of labor in type Ⅰ - Ⅲ CCAM gradually increased. The comparison of the induction rates of labor in different subtypes of CCAM showed statistically significant differences (P<0.05).The follow-up of CCAM fetuses revealed that there was no statistically significant difference in the proportion of lesion volume reduction among different subtypes (P>0.05). The proportion of pulmonary consolidation and the proportion of those with respiratory symptoms in type Ⅰ- Ⅲ CCAM increased successively (P<0.05). 【Conclusion】Prenatal ultrasound is an effective tool for differentiating fetal CCAM and is of great value in predicting disease prognosis and improving the clinical outcome of neonates.
Key wordsCystic Adenomatoid Malformation of Lung Congenital    Fetus    Ultrasonography Prenatal    Prognosis
收稿日期: 2024-12-19     
中图分类号:  R714.431  
引用本文:   
杨冬冬. 胎儿先天性肺囊腺瘤样畸形的产前超声特征及其对胎儿预后的影响[J]. 医学临床研究, 2025, 42(4): 612-614.
YANG Dongdong. Prenatal Ultrasonic Features of Fetal Congenital Cystic Adenomatoid Malformation and their Impact on Fetal Prognosis. JOURNAL OF CLINICAL RESEARCH, 2025, 42(4): 612-614.
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http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2025.04.015     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2025/V42/I4/612
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