Abstract：【Objective】To explore the risk factors of placental abruption in pregnant women with hypertensive disorder complicating pregnancy (HDCP). 【Methods】 A total of 80 HDCP pregnant women admitted to the Obstetrics and Gynecology Department of the Lantian County People's Hospital from July 2018 to July 2021 were selected and divided into early exfoliation group (n=12) and non early exfoliation group (n=68) based on the examination results after admission. The age,pre pregnancy body mass index (BMI),weight gain during pregnancy,history of diabetes,number of pregnant fetuses,history of cesarean section,history of abortion,family history of hypertension,educational level and renal function index [serum urea nitrogen,serum creatinine,uric acid level,glomerular filtration rate] of the two groups were compared,Multiple regression analysis was used to identify the risk factors for placental abruption in HDCP pregnant women. 【Results】There was no significant difference in age,diabetes,multiple pregnancy,cesarean section,abortion,smoking,education,and serum urea nitrogen between the two groups (P>0.05); The pre pregnancy BMI,gestational weight gain,and glomerular filtration rate of the early exfoliation group were lower than those of the non early exfoliation group,while the proportion of individuals with a family history of hypertension,serum creatinine,and uric acid levels were higher than those of the non early exfoliation group (P<0.05). The ROC curve analysis results show that pre pregnancy BMI,gestational weight gain,serum creatinine,uric acid,and glomerular filtration rate can all predict the occurrence of placental abruption in HDCP pregnant women,with areas under the curves of 0.713,0.879,0.849,0.686,and 0.846,respectively. The results of multivariate analysis showed that pre pregnancy BMI<23.51 kg/m2,pregnancy weight gain<14.10 kg,family history of hypertension,and serum creatinine ≥ 66.13 μmol/L,uric acid ≥361.34 μmol/L and glomerular filtration rate<111.86 mL/min were risk factors for placental abruption in HDCP pregnant women (P<0.05). 【Conclusions】The impact of pre pregnancy BMI,gestational weight gain,family history of hypertension,serum creatinine,uric acid,and glomerular filtration rate on placental abruption in HDCP pregnant women needs to be strengthened in clinical practice to prevent the occurrence of placental abruption.
王薇, 贾宝玲. 妊娠期高血压疾病孕妇发生胎盘早剥的危险因素分析[J]. 医学临床研究, 2023, 40(8): 1218-1220.
WANG Wei, JIA Bao-ling. Analysis of Risk Factors for Placental Abruption in Pregnant Women with Gestational Hypertension. JOURNAL OF CLINICAL RESEARCH, 2023, 40(8): 1218-1220.
2023, Vol. 40 
