Abstract：【Objective】To investigate the changes and correlation of serum homocysteine (Hcy) levels,blood pressure,and myocardial injury markers in patients with gestational hypertension. 【Methods】A total of 68 patients with gestational hypertension admitted to our hospital from October 2018 to October 2021 (observation group) were selected,and 68 normal pregnant women who underwent regular prenatal examinations in our hospital were also selected. We compared the general information and levels of Hcy,daytime systolic blood pressure (SBP),daytime diastolic blood pressure (DBP),nighttime SBP,nighttime DBP,and troponin I(cTnI),creatine kinase isoenzyme (CK-MB),N-terminal B-type brain natriuretic peptide precursor(NT-proBNP),and lactate dehydrogenase (LDH) between two groups of pregnant women,and analyzed the correlation between Hcy levels,blood pressure,and myocardial injury markers. 【Results】 There was no statistically significant difference in general information between the two groups of pregnant women (P>0.05); The Hcy levels,daytime SBP,daytime DBP,nighttime SBP,and nighttime DBP in the observation group were significantly higher than those in the control group (P<0.05); The levels of cTnI, NT-proBNP,CK-MB,and LDH in the observation group were significantly higher than those in the control group (P<0.05); Correlation analysis showed that Hcy,SBP,DBP were positively correlated with cTnI,CK-MB,NT-proBNP,and LDH (P<0.05). 【Conclusion】 The levels of serum Hcy and blood pressure are correlated with myocardial injury in patients with gestational hypertension,and have certain reference value in the diagnosis of myocardial injury in patients with gestational hypertension. Clinicians should pay more attention.
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2023, Vol. 40 
