GLS评估高血压患者左室舒张功能的应用价值

doi:10.3969/j.issn.1671-7171.2023.06.028

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摘要【目的】探讨左室纵向长轴应变(GLS) 评估高血压患者左室舒张功能的应用价值。【方法】选择2017年6月至2019年11月于本院门诊就诊并进行随访的55例原发性高血压患者,根据患者初始血压水平选用合适的降压药物,治疗前及治疗1个月后进行超声心动图检查,记录患者舒张早期血流峰速度/舒张早期二尖瓣环运动峰速度(E/e') 、E/舒张晚期血流峰速度(A)、e'、GLS、平均动脉压(MAP)、脉压(PP)、左房容积指数(LAVI)、左心室重量指数(LVMI),心导管检测左室舒张末压(LVEDP),采用Pearson相关性分析LVEDP与其他超声心动图指标的相关性。【结果】治疗1个月,高血压患者SBP、DBP、PP、MAP、E/e'、GLS均低于治疗前,e'高于治疗前,差异有统计学意义(P<0.05)。降压治疗1个月后,心脏超声心动图各指标变化幅度采用配对秩和检验,结果显示,GLS的变化幅度均显著高于 LAVI、e'、E/e'的变化幅度,差异有统计学意义(P<0.05)。 Pearson相关性分析显示,LVEDP与GLS 及E/e'呈显著正相关(P<0.05),LVEDP与e'呈负相关(P<0.05),LVEDP与LAVI、E/A无显著相关性(P>0.05)。【结论】 GLS在评估高血压患者降压治疗后左室舒张功能的价值较高。

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关键词 ：高血压, 心室功能,左

Abstract：【Objective】 To explore the application value of left ventricular longitudinal long axis strain (GLS) in evaluating left ventricular diastolic function in hypertensive patients. 【Methods】 A total of 55 patients with primary hypertension who visited our outpatient department from June 2017 to November 2019 and were followed up were selected,and appropriate antihypertensive drugs were selected based on their initial blood pressure levels. Before treatment and one month after treatment,echocardiography was performed to record the patients' early diastolic peak velocity/early diastolic mitral annulus peak velocity (E/e '),early diastolic peak velocity/late diastolic peak velocity (E/A),e',GLS,Mean arterial pressure (MAP),pulse pressure (PP),left atrial volume index (LAVI),left ventricular mass index (LVMI),and left ventricular end diastolic pressure (LVEDP) through cardiac catheters,Pearson correlation analysis was used to analyze the correlation between LVEDP and other echocardiographic indicators.【Results】 After one month of treatment,SBP,DBP,PP,MAP,E/e ',GLS of hypertensive patients were lower than those before treatment,and e' was higher than those before treatment,with a statistically significant difference (P<0.05). After one month of antihypertensive treatment,the amplitude of changes in various indicators of cardiac echocardiography was tested using paired rank sum test. The results showed that the amplitude of changes in GLS was significantly higher than that in LAVI,e ',E/e',and the difference was statistically significant (P<0.05). Pearson correlation analysis showed that LVEDP was significantly positively correlated with GLS and E/e '(P<0.05),while LVEDP was negatively correlated with e' (P<0.05). LVEDP was not significantly correlated with LAVI and E/A (P>0.05). 【Conclusion】 GLS has a high value in evaluating left ventricular diastolic function in hypertensive patients after antihypertensive treatment.

Key words： Hypertension Ventricular Function,Left

收稿日期: 2023-02-27

中图分类号:

R544.1

通讯作者: *E-mail: huihui667013@sina.com

引用本文:

段岚, 罗辉, 彭汉武, 刘斌, 左骑, 肖宝, 李曾. GLS评估高血压患者左室舒张功能的应用价值[J]. 医学临床研究, 2023, 40(6): 899-901.
DUAN Lan, LUO Hui, PENG Han-wu, et al. The Application Value of GLS in Evaluating Left Ventricular Diastolic Function in Hypertensive Patients. JOURNAL OF CLINICAL RESEARCH, 2023, 40(6): 899-901.

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http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2023.06.028 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2023/V40/I6/899