DCE-MRI参数对不同病理结果子宫肌瘤患者的鉴别价值

doi:10.3969/j.issn.1671-7171.2023.06.016

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摘要【目的】探讨动态对比增强磁共振成像(DCE-MRI)参数对不同病理结果子宫肌瘤患者的鉴别价值。【方法】选取2017年2月至2022年2月安康职业技术学院附属医院安康市中心医院收治的164例子宫肌瘤患者,按照病理诊断结果分为A组(普通型,n=77)、B组(富于细胞型,n=49)、C组(退变型,n=38)。所有患者均使用磁共振诊断仪进行扫描,比较三组血管外细胞外间隙容积分数(V_e)、血管间隙容积分数(V_p)、毛细血管表面通透性(PS)、血浆灌注量(F_p);采用受试者工作特征(ROC)曲线分析V_e、V_p、F_p对富于细胞型子宫肌瘤的诊断价值;以病理诊断结果为金标准,分析V_e、V_p、F_p联合诊断富于细胞型子宫肌瘤的效能。【结果】 B组、A组、C组V_e、V_p、F_p依次减少,且组间比较差异有统计学意义(P<0.05); B组PS显著高于A组、C组,差异有统计学意义(P<0.05)。ROC曲线分析证实:V_e、V_p、F_p可用于诊断富于细胞型子宫肌瘤,曲线下面积分别为0.779、0.836、0.808。一致性分析结果显示:V_e、V_p、F_p联合诊断富于细胞型子宫肌瘤的敏感度为83.67%,特异度为92.17%,准确率为89.63%。【结论】 DCE-MRI参数可用于鉴别不同病理分型的子宫肌瘤,且V_e、V_p、F_p联合诊断富于细胞型子宫肌瘤的效能更高。

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	吴宗妍
	吴宗霞

关键词 ：平滑肌瘤/影像诊断, 平滑肌瘤/病理学, 磁共振成像

Abstract：【Objective】 To explore the differentially diagnostic value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) parameters in patients with uterine fibroids with different pathological results. 【Methods】 A total of 164 patients with uterine fibroids admitted to Ankang Central Hospital Affiliated Hospital of Ankang Vocational and Technical College from February 2017 to February 2022 were divided into group A (77 cases of ordinary type),group B (49 cases of cellular type),and group C (38 cases of degenerative type) based on pathological diagnosis. Using a magnetic resonance diagnostic instrument for scanning,the volume fraction of extracellular space (V_e),volume fraction of vascular space (V_p),capillary surface permeability (PS),and plasma perfusion volume (F_p) among three groups were recorded. The values of V_e,V_p,and F_p in diagnosing cellular uterine fibroids through ROC analysis were evaluated. We also used pathological diagnosis results as the gold standard to analyze the efficacy of V_e,V_p,and F_p combined in diagnosing cellular uterine fibroids. 【Results】 There were significant differences in V_e,V_p,and F_p among the three groups,with values of V_e,V_p,and F_p showing in Group B>Group A>Group C (P<0.05). PS in Group B was higher than that in Group A and C (P<0.05). ROC analysis confirmed that V_e,V_p,and F_p could be used for the diagnosis of cellular uterine fibroids,with areas under the curve of 0.779,0.836,and 0.808,respectively. The results of consistency analysis showed that the sensitivity,specificity,and accuracy of the combined diagnosis of V_e,V_p,and F_p for cellular uterine fibroids were 83.67%,92.17% and 89.63%,respectively. 【Conclusion】 DCE-MRI parameters can be used to distinguish uterine fibroids of different pathological types,and the combination of V_e,V_p,and F_p has a more prominent diagnostic efficacy for cellular uterine fibroids,which can be used for clinical diagnosis.

Key words： Leiomyoma/DG Leiomyoma/PA Magnetic Resonance Imagin

收稿日期: 2022-08-29

中图分类号:

R711.74

通讯作者: *E-mail:137930922@qq.com

引用本文:

吴宗妍, 吴宗霞. DCE-MRI参数对不同病理结果子宫肌瘤患者的鉴别价值[J]. 医学临床研究, 2023, 40(6): 855-858.
WU Zong-yan, WU Zong-xia. Differentially Diagnostic Value of DCE-MRI Parameters in Patients with Uterine Fibroids with Different Pathological Results. JOURNAL OF CLINICAL RESEARCH, 2023, 40(6): 855-858.

链接本文:

http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2023.06.016 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2023/V40/I6/855

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